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List of works by David G Drubin

4D cell biology: big data image analytics and lattice light-sheet imaging reveal dynamics of clathrin-mediated endocytosis in stem cell-derived intestinal organoids.

scientific article published on 06 September 2018

A Hip1R-cortactin complex negatively regulates actin assembly associated with endocytosis

scientific article

A Pan1/End3/Sla1 complex links Arp2/3-mediated actin assembly to sites of clathrin-mediated endocytosis

scientific article

A computable cellular stress network model for non-diseased pulmonary and cardiovascular tissue

scientific article

A modular design for the clathrin- and actin-mediated endocytosis machinery

scientific article

A neurotoxic phospholipase A2 impairs yeast amphiphysin activity and reduces endocytosis

scientific article published on 23 July 2012

A protein interaction map of the mitotic spindle

scientific article

A role for cortactin in Listeria monocytogenes invasion of NIH 3T3 cells, but not in its intracellular motility

scientific article published on April 2006

A yeast killer toxin screen provides insights into a/b toxin entry, trafficking, and killing mechanisms

scientific article published on October 2009

Actin and dynamin2 dynamics and interplay during clathrin-mediated endocytosis

scientific article

Actin and septin ultrastructures at the budding yeast cell cortex

scientific article

Actin dynamics coupled to clathrin-coated vesicle formation at the trans-Golgi network

scientific article

Actin filament elongation in Arp2/3-derived networks is controlled by three distinct mechanisms

scientific article

Actin lessons from pathogens

scientific article published on February 2004

All together now: how and why scientific communities should develop best practice guidelines

scientific article published on June 2016

An Engineered Minimal WASP-Myosin Fusion Protein Reveals Essential Functions for Endocytosis

scientific article

An MBoC Favorite: Creativity and graduate education.

scientific article published in April 2012

Analysis of yeast endocytic site formation and maturation through a regulatory transition point

scientific article published in February 2012

Any jackass can trash a manuscript, but it takes good scholarship to create one (how MBoC promotes civil and constructive peer review) ⬇️

scientific article published on March 1, 2011

Architecture and flexibility of the yeast Ndc80 kinetochore complex

scientific article published on 05 September 2008

Architecture of the Dam1 kinetochore ring complex and implications for microtubule-driven assembly and force-coupling mechanisms

scientific article published on 22 July 2007

Architecture of the budding yeast kinetochore reveals a conserved molecular core

scientific article

Are you being served?

scientific article published on January 2010

Arp2/3 ATP hydrolysis-catalysed branch dissociation is critical for endocytic force generation

scientific article

Bayesian modeling of the yeast SH3 domain interactome predicts spatiotemporal dynamics of endocytosis proteins

scientific article

Branched actin networks are organized for asymmetric force production during clathrin-mediated endocytosis in mammalian cells

scientific article published in 2022

Building Distinct Actin Filament Networks in a Common Cytoplasm ⬇️

scientific article published on July 26, 2011

Casein kinase 1 promotes initiation of clathrin-mediated endocytosis

scientific article

Clathrin-mediated endocytosis in budding yeast ⬇️

scientific article published on October 20, 2011

Clathrin-mediated endocytosis in budding yeast at a glance

scientific article

Clathrin: an amazing multifunctional dreamcoat?

scientific article

Cofilin promotes rapid actin filament turnover in vivo

scientific article published in Nature

Cofilin recruitment and function during actin-mediated endocytosis dictated by actin nucleotide state

scientific article

Control of lipid organization and actin assembly during clathrin-mediated endocytosis by the cytoplasmic tail of the rhomboid protein Rbd2

scientific article

Control of the spindle checkpoint by lateral kinetochore attachment and limited Mad1 recruitment

scientific article

Design principles for robust vesiculation in clathrin-mediated endocytosis

scientific article published on 26 January 2017

Direct comparison of clathrin-mediated endocytosis in budding and fission yeast reveals conserved and evolvable features

scientific article published on 12 December 2019

Direct regulation of Arp2/3 complex activity and function by the actin binding protein coronin

scientific article

Dissecting principles governing actin assembly using yeast extracts

scientific article published in January 2014

Dynamic phosphoregulation of the cortical actin cytoskeleton and endocytic machinery revealed by real-time chemical genetic analysis

scientific article

Dynein-driven mitotic spindle positioning restricted to anaphase by She1p inhibition of dynactin recruitment

scientific article

Early-arriving Syp1p and Ede1p function in endocytic site placement and formation in budding yeast

scientific article

Effects of Arp2 and Arp3 nucleotide-binding pocket mutations on Arp2/3 complex function

scientific article

Endocytic internalization in budding yeast requires coordinated actin nucleation and myosin motor activity

scientific article

Endocytic vesicle scission by lipid phase boundary forces

scholarly article

English as the universal language of science: opportunities and challenges ⬇️

scientific article (publication date: April 2012)

Experimentalist meets theoretician: a tale of two scientific cultures

scientific article published on 05 May 2010

Formation of a dynamic kinetochore- microtubule interface through assembly of the Dam1 ring complex

scientific article

Genome-edited human stem cells expressing fluorescently labeled endocytic markers allow quantitative analysis of clathrin-mediated endocytosis during differentiation

scientific article published on 06 July 2018

Great science inspires us to tackle the issue of data reproducibility

scientific article published in November 2015

Impact of genome-wide functional analyses on cell biology research

scientific article

Inspiration from inspirational cell biologists

scientific article published on November 2014

Interaction of CK1δ with γTuSC ensures proper microtubule assembly and spindle positioning

scientific article

Interaction of Sla2p's ANTH domain with PtdIns(4,5)P2 is important for actin-dependent endocytic internalization

scientific article

Interaction of the endocytic scaffold protein Pan1 with the type I myosins contributes to the late stages of endocytosis

scientific article

Ipl1/Aurora-dependent phosphorylation of Sli15/INCENP regulates CPC–spindle interaction to ensure proper microtubule dynamics ⬇️

scientific article published on July 4, 2011

Isolation and partial purification of the Saccharomyces cerevisiae cytokinetic apparatus

scientific article published on January 2010

Kinesins relocalize the chromosomal passenger complex to the midzone for spindle disassembly

scientific article published on 21 March 2018

Kinetochore protein interactions and their regulation by the Aurora kinase Ipl1p

scientific article

Learning a prior on regulatory potential from eQTL data

scientific article

Loss of Aip1 reveals a role in maintaining the actin monomer pool and an in vivo oligomer assembly pathway

scientific article

Lsb1 is a negative regulator of las17 dependent actin polymerization involved in endocytosis

scientific article (publication date: 2013)

MBoC 2011: same values, improved feng shui ⬇️

scientific article published on November 1, 2011

MBoC celebrates its first 20 years ⬇️

scientific article published on November 1, 2012

MBoC improves recognition of co-first authors

scientific article published on July 2014

Machine-Learning-Based Analysis in Genome-Edited Cells Reveals the Efficiency of Clathrin-Mediated Endocytosis

scientific article

Mammalian Abp1, a Signal-Responsive F-Actin–Binding Protein, Links the Actin Cytoskeleton to Endocytosis via the Gtpase Dynamin

article published in 2001

Mechanochemical crosstalk during endocytic vesicle formation

scientific article

Microtubule dynamics regulation reconstituted in budding yeast lysates

scientific article published on 24 September 2018

Mitotic spindle disassembly occurs via distinct subprocesses driven by the anaphase-promoting complex, Aurora B kinase, and kinesin-8 ⬇️

scientific article (publication date: 15 November 2010)

Modeling Vesicle Traffic Reveals Unexpected Consequences for Cdc42p-Mediated Polarity Establishment ⬇️

scientific article published on February 8, 2011

Multiple pathways regulate endocytic coat disassembly in Saccharomyces cerevisiae for optimal downstream trafficking

scientific article

Multiple roles for cyclin G-associated kinase in clathrin-mediated sorting events

scientific article published in December 2005

Myosin 1E coordinates actin assembly and cargo trafficking during clathrin-mediated endocytosis ⬇️

scientific article published on June 6, 2012

Negative regulation of yeast WASp by two SH3 domain-containing proteins

scientific article

No shortcuts for research assessment

scientific article

Observing the cell in its native state: Imaging subcellular dynamics in multicellular organisms

scientific article published in April 2018

Orm protein phosphoregulation mediates transient sphingolipid biosynthesis response to heat stress via the Pkh-Ypk and Cdc55-PP2A pathways ⬇️

scientific article published on April 25, 2012

Overlapping kinetochore targets of CK2 and Aurora B kinases in mitotic regulation ⬇️

scientific article published on August 1, 2011

PALM reading: Seeing the future of cell biology at higher resolution

scientific article

Phospho-regulation of kinetochore-microtubule attachments by the Aurora kinase Ipl1p

scientific article

Phosphoregulation of Arp2/3-dependent actin assembly during receptor-mediated endocytosis

scientific article

Phosphorylation regulates kinase and microtubule binding activities of the budding yeast chromosomal passenger complex in vitro

scientific article published on 27 June 2013

Pik1-ing clathrin adaptors ⬇️

scientific article published on February 19, 2012

Principles of self-organization and load adaptation by the actin cytoskeleton during clathrin-mediated endocytosis

scientific article published on 17 January 2020

Purification of glutathione S-transferase fusion proteins from yeast.

scientific article

Quantitative analysis of yeast internal architecture using soft X‐ray tomography ⬇️

scientific article published on December 22, 2010

RNAi-mediated Hip1R silencing results in stable association between the endocytic machinery and the actin assembly machinery

scientific article

Rapid and efficient clathrin-mediated endocytosis revealed in genome-edited mammalian cells ⬇️

scientific article published on February 6, 2011

Reconstitution and Protein Composition Analysis of Endocytic Actin Patches ⬇️

scientific article published on October 28, 2010

Regulation of clathrin-mediated endocytosis by dynamic ubiquitination and deubiquitination

scientific article

Regulation of mitotic spindle disassembly by an environmental stress-sensing pathway in budding yeast

scientific article

Requirements for recruitment of a G protein-coupled receptor to clathrin-coated pits in budding yeast

scientific article published on December 2009

Selection and stabilization of endocytic sites by Ede1, a yeast functional homologue of human Eps15.

scientific article

Setting the bar for cell biology best practices

scientific article published on September 2016

Simple centromere, complex kinetochore: linking spindle microtubules and centromeric DNA in budding yeast

scientific article

Spatial dynamics of receptor-mediated endocytic trafficking in budding yeast revealed by using fluorescent alpha-factor derivatives

scientific article

Spindle assembly requires complete disassembly of spindle remnants from the previous cell cycle ⬇️

scientific article published on November 16, 2011

Spontaneous receptor-independent heterotrimeric G-protein signalling in an RGS mutant.

scientific article

Stem cells: the new "model organism".

scientific article published on June 2017

Structures and functions of yeast kinetochore complexes

scientific article published on January 2007

Switch-like Arp2/3 activation upon WASP and WIP recruitment to an apparent threshold level by multivalent linker proteins in vivo

scientific article published on 16 August 2017

The 50th anniversary of the ASCB: celebrating by looking forward

scientific article published on November 2010

The Dam1 kinetochore ring complex moves processively on depolymerizing microtubule ends.

scientific article published on 15 January 2006

The Dam1 ring binds microtubules strongly enough to be a processive as well as energy-efficient coupler for chromosome motion

scientific article

The Dam1 ring binds to the E-hook of tubulin and diffuses along the microtubule ⬇️

scientific article published on December 17, 2010

The FEAR protein Slk19 restricts Cdc14 phosphatase to the nucleus until the end of anaphase, regulating its participation in mitotic exit in Saccharomyces cerevisiae

scientific article

The Saccharomyces cerevisiae Mob2p-Cbk1p kinase complex promotes polarized growth and acts with the mitotic exit network to facilitate daughter cell-specific localization of Ace2p transcription factor

scientific article

The Scientific Society Publisher Alliance delivers an important message

scientific article published in December 2017

The actin-regulating kinase Prk1p negatively regulates Scd5p, a suppressor of clathrin deficiency, in actin organization and endocytosis.

scientific article

The budding yeast endocytic pathway

scientific article published on November 2006

The functions of anionic phospholipids during clathrin-mediated endocytosis site initiation and vesicle formation ⬇️

scientific article published on October 24, 2012

The mechanochemistry of endocytosis

scientific article

The mismeasure of scientific research articles and why MBoC quickly embraced preprints

scientific article published on November 2016

Toxicopanomics: Applications of Genomics, Transcriptomics, Proteomics, and Lipidomics in Predictive Mechanistic Toxicology

Type I myosins anchor actin assembly to the plasma membrane during clathrin-mediated endocytosis

scientific article published on 18 January 2019

Ultrastructural imaging of endocytic sites in Saccharomyces cerevisiae by transmission electron microscopy and immunolabeling

scientific article

Unusual binding properties of the SH3 domain of the yeast actin-binding protein Abp1: structural and functional analysis

scientific article

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