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List of works by Gianluigi Forloni

A New Face for Old Antibiotics: Tetracyclines in Treatment of Amyloidoses

scientific article published on May 8, 2013

A Rational Structured Epitope Defines a Distinct Subclass of Toxic Amyloid-beta Oligomers

scientific article published on 16 April 2018

A consensus protocol for functional connectivity analysis in the rat brain

scientific article published on 27 March 2023

A new fluorogenic peptide determines proteasome activity in single cells.

scientific article published on October 2010

A new three dimensional biomimetic hydrogel to deliver factors secreted by human mesenchymal stem cells in spinal cord injury.

scientific article published on 21 October 2015

Activation of olivocerebellar fibers induces an increase in CGRP cerebellar binding sites

scientific article published on June 30, 1992

Alpha-synuclein oligomers impair memory through glial cell activation and via Toll-like receptor 2.

scientific article published on 16 February 2018

Alzheimer's Disease and Neurotransmission Gene Variants: Focus on Their Effects on Psychiatric Comorbidities and Inflammatory Parameters

scientific article published on 16 May 2019

Alzheimer's Disease, Oligomers, and Inflammation.

scientific article published in January 2018

An N-terminal fragment of the prion protein binds to amyloid-β oligomers and inhibits their neurotoxicity in vivo

scientific article published on 28 January 2013

Antibody-functionalized polymer nanoparticle leading to memory recovery in Alzheimer's disease-like transgenic mouse model.

scientific article published on 14 December 2017

Applicability of [11C]PIB micro-PET imaging for in vivo follow-up of anti-amyloid treatment effects in APP23 mouse model

scientific article published on 15 May 2017

Association between CSF biomarkers, hippocampal volume and cognitive function in patients with amnestic mild cognitive impairment (MCI).

scientific article published on 18 January 2017

Association between Sirtuin 1 Gene rs10997870 Polymorphism and Suicide Behaviors in Bipolar Disorder.

scientific article published on 16 July 2016

Association between Sirtuin 2 gene rs10410544 polymorphism and depression in Alzheimer's disease in two independent European samples.

scientific article published on 28 May 2013

Asymptomatic carriers of presenilin-1 E318G variant show no cerebrospinal fluid biochemical signs suggestive of Alzheimer's disease in a family with late-onset dementia

scientific article published on 01 January 2019

Biomarker Matrix to Track Short Term Disease Progression in Amnestic Mild Cognitive Impairment Patients with Prodromal Alzheimer's Disease

scientific article published on 01 January 2019

Biophysical and in Vivo Studies Identify a New Natural-Based Polyphenol, Counteracting Aβ Oligomerization in Vitro and Aβ Oligomer-Mediated Memory Impairment and Neuroinflammation in an Acute Mouse Model of Alzheimer's Disease

scientific article published on 28 October 2019

Body mass index, cognition, disability, APOE genotype, and mortality: the "Treviso Longeva" Study.

scientific article

Brain aging and dementia during the transition from late adulthood to old age: design and methodology of the "Invece.Ab" population-based study.

scientific article

C9ORF72 Hexanucleotide Repeat Number in Frontotemporal Lobar Degeneration: A Genotype-Phenotype Correlation Study

scientific article published on 01 January 2015

C9ORF72 hexanucleotide repeat number in frontotemporal lobar degeneration: a genotype-phenotype correlation study

scientific article published in January 2014

CHRNA7 Gene and Response to Cholinesterase Inhibitors in an Italian Cohort of Alzheimer's Disease Patients.

scientific article

Cellular prion protein neither binds to alpha-synuclein oligomers nor mediates their detrimental effects

scientific article published on 01 February 2019

Chemical exchange saturation transfer MRI shows low cerebral 2-deoxy-D-glucose uptake in a model of Alzheimer's Disease.

scientific article

Chronic infusion of quinolinic acid in rat striatum: effects on discrete neuronal populations

scientific article published on April 1, 1992

Clinical and biomarker profiling of prodromal Alzheimer's disease in workpackage 5 of the Innovative Medicines Initiative PharmaCog project: a 'European ADNI study'.

scientific article

Clinical trials of prion disease therapeutics

scientific article published on 01 February 2019

Cognitive Deficits Associated with Alteration of Synaptic Metaplasticity Precede Plaque Deposition in AβPP23 Transgenic Mice

scientific article published on January 1, 2010

Comparative Magnetic Resonance Imaging and Histopathological Correlates in Two SOD1 Transgenic Mouse Models of Amyotrophic Lateral Sclerosis

scientific article

Comparison of the effects of the stereoisomers of fenfluramine on the acetylcholine content of rat striatum, hippocampus and nucleus accumbens

scientific article published on March 1, 1980

Corrected QT Interval Prolongation in Psychopharmacological Treatment and Its Modulation by Genetic Variation

scientific article published on 13 December 2018

Culture of dorsal root ganglion neurons from aged rats: effects of acetyl-L-carnitine and NGF

scientific article published on August 1, 1992

Current Options for Cell Therapy in Spinal Cord Injury

scientific article published on 12 August 2017

Decreased [3H]hemicholinium binding to high-affinity choline uptake sites in aged rat brain

scientific article published on January 20, 1992

Densitometric Quantification of Neuronal Viability by Computerized Image Analysis

scientific article published on November 1, 1997

Detection of prion seeding activity in the olfactory mucosa of patients with Fatal Familial Insomnia

scientific article

Development and analysis of semi-interpenetrating polymer networks for brain injection in neurodegenerative disorders.

scientific article published on 27 November 2013

Differential transgene expression patterns in Alzheimer mouse models revealed by novel human amyloid precursor protein-specific antibodies

scientific article published on 29 July 2016

Disease tracking markers for Alzheimer's disease at the prodromal (MCI) stage.

scientific article

Doxycycline counteracts neuroinflammation restoring memory in Alzheimer's disease mouse models

scientific article published on 12 June 2018

Doxycycline in Creutzfeldt-Jakob disease: a phase 2, randomised, double-blind, placebo-controlled trial.

scientific article published on 8 January 2014

Early modulation of pro-inflammatory microglia by minocycline loaded nanoparticles confers long lasting protection after spinal cord injury

article

Effects of SORL1 gene on Alzheimer's disease. Focus on gender, neuropsychiatric symptoms and pro-inflammatory cytokines.

scientific article published in February 2013

Effects of pharmacological agents, sleep deprivation, hypoxia and transcranial magnetic stimulation on electroencephalographic rhythms in rodents: towards translational challenge models for drug discovery in Alzheimer's disease.

scientific article published on 04 October 2012

Electrocardiogram Alterations Associated With Psychotropic Drug Use and CACNA1C Gene Variants in Three Independent Samples.

scientific article published on 28 November 2016

Environmental enrichment lessens cognitive decline in APP23 mice without affecting brain sirtuin expression

scientific article

Exome sequencing in an Italian family with Alzheimer's disease points to a role for seizure-related gene 6 (SEZ6) rare variant R615H

article

Exploring Alzheimer's disease mouse brain through X-ray phase contrast tomography: From the cell to the organ

scientific article published on 18 September 2018

Expression of CGRP binding sites in the developing rat cerebellum

scientific article published on June 30, 1992

Expression of GAL mRNA in rat hypothalamus: effect of frontal deafferentation and colchicine treatment

scientific article published on July 1, 1992

Frontotemporal Lobar Degeneration and MicroRNAs

scientific article

Genetic Variants Within Key Nodes of the Cascade of Antipsychotic Mechanisms: Effects on Antipsychotic Response and Schizophrenia Psychopathology in a Naturalistic Treatment Setting in Two Independent Korean and Italian Samples

scientific article published on 16 May 2017

Genetic Variants Within Molecular Targets of Antipsychotic Treatment: Effects on Treatment Response, Schizophrenia Risk, and Psychopathological Features.

scientific article

Genetics of psychotropic medication induced side effects in two independent samples of bipolar patients

scientific article published on 17 August 2014

Hydrogel-based nanocomposites and mesenchymal stem cells: a promising synergistic strategy for neurodegenerative disorders therapy

scientific article

Impact of 5-HTTLPR polymorphism on alexithymia in alcoholic patients after detoxification treatment

scientific article published in September 2013

In Vivo Application of beta Amyloid Oligomers: A Simple Tool to Evaluate Mechanisms of Action and New Therapeutic Approaches

scientific article published on January 1, 2014

In vivo PET imaging of beta-amyloid deposition in mouse models of Alzheimer's disease with a high specific activity PET imaging agent [(18)F]flutemetamol

scientific article published on August 2014

Influence of cell culture conditions on the protective effect of antioxidants against β-amyloid toxicity: studies with lazaroids

scientific article published on August 1, 1997

Influence of socio-demographic features and apolipoprotein E epsilon 4 expression on the prevalence of dementia and cognitive impairment in a population of 70-74-year olds: the InveCe.Ab study.

scientific article published on 25 November 2014

Interferon-γ Potentiates Interleukin (IL)-6 and Tumor Necrosis Factor-α But Not IL-1β Induced by Endotoxin in the Brain

scientific article published on December 1, 1997

Longitudinal amyloid imaging in mouse brain with 11C-PIB: comparison of APP23, Tg2576, and APPswe-PS1dE9 mouse models of Alzheimer disease.

scientific article

Loss of exosomes in progranulin-associated frontotemporal dementia

scientific article published on 7 January 2016

Macroautophagy and the proteasome are differently involved in the degradation of alpha-synuclein wild type and mutated A30P in an in vitro inducible model (PC12/TetOn).

scientific article

Melatonin and the Charlson Comorbidity Index (CCI): the Treviso Longeva (Trelong) study

scientific article published in July 2014

Mesenchymal stem cells encapsulated into biomimetic hydrogel scaffold gradually release CCL2 chemokine in situ preserving cytoarchitecture and promoting functional recovery in spinal cord injury.

scientific article published on 2 April 2018

Modifications in recognition sites for neurotransmitters in rat hippocampus by kainic acid lesion

scientific article published on September 5, 1983

Modulation of cortical in vivo acetylcholine release by the basal nuclear complex: role of the pontomesencephalic tegmental area

scientific article published on November 1, 1991

Modulation of human longevity by SIRT3 single nucleotide polymorphisms in the prospective study “Treviso Longeva (TRELONG)”

scientific article published on July 10, 2013

Modulation of the hippocampal α-adrenoceptor population by lesion of the serotonergic raphe-hippocampal pathway in rats

scientific article published on March 29, 1982

Multifunctional liposomes delay phenotype progression and prevent memory impairment in a presymptomatic stage mouse model of Alzheimer disease

scientific article published on 10 May 2017

Multifunctional liposomes reduce brain β-amyloid burden and ameliorate memory impairment in Alzheimer's disease mouse models.

scientific article

Nanocomposites for Neurodegenerative Diseases: Hydrogel-Nanoparticle Combinations for a Challenging Drug Delivery

scientific article published on December 1, 2011

Nanovector-Mediated Drug Delivery in Spinal Cord Injury: A Multitarget Approach

scientific article published on 25 February 2019

Nanovector-mediated drug delivery for spinal cord injury treatment.

scientific article published on 21 May 2014

Nephrin expression in adult rodent central nervous system and its interaction with glutamate receptors.

scientific article

Neuroinflammation and the Gut Microbiota: Possible Alternative Therapeutic Targets to Counteract Alzheimer's Disease?

scientific article published on 18 October 2019

Neuroplasticity and second messenger pathways in antidepressant efficacy: pharmacogenetic results from a prospective trial investigating treatment resistance.

scientific article published on 4 March 2017

Neuroprotective Effects of Doxycycline in the R6/2 Mouse Model of Huntington's Disease

scientific article published on 26 December 2019

Neuroprotective properties of resveratrol in different neurodegenerative disorders.

scientific article published on September 2010

Novel targets in Alzheimer's disease: a special focus on microglia.

scientific article published on 30 January 2018

ONGOING ELECTROENCEPHALOGRAPHIC ACTIVITY ASSOCIATED WITH CORTICAL AROUSAL IN TRANSGENIC PDAPP MICE (hAPP V717F).

scientific article

Oligomeropathies and pathogenesis of Alzheimer and Parkinson's diseases.

scientific article published on 31 March 2016

On-Going Frontal Alpha Rhythms Are Dominant in Passive State and Desynchronize in Active State in Adult Gray Mouse Lemurs

scientific article published on 30 November 2015

On-going electroencephalographic rhythms related to cortical arousal in wild-type mice: the effect of aging.

scientific article published on 15 September 2016

Peripheral inflammation exacerbates α-synuclein toxicity and neuropathology in Parkinson's models

scientific article published on 22 July 2020

Pharmacogenomics in Alzheimer's disease: a genome-wide association study of response to cholinesterase inhibitors.

scientific article published on 29 January 2013

Plasma Aβ42 as a Biomarker of Prodromal Alzheimer's Disease Progression in Patients with Amnestic Mild Cognitive Impairment: Evidence from the PharmaCog/E-ADNI Study

scientific article published on 01 January 2019

Plasma and brain concentrations of doxycycline after single and repeated doses in wild-type and APP23 mice

scientific article published on 05 November 2018

Plasmatic Hippuric Acid as a Hallmark of Frailty in an Italian Cohort: The Mediation Effect of Fruit–Vegetable Intake

scientific article published in 2021

Pleiotropic genes in psychiatry: Calcium channels and the stress-related FKBP5 gene in antidepressant resistance.

scientific article published on 5 October 2017

Polymeric nanoparticle system to target activated microglia/macrophages in spinal cord injury

scientific article published on 10 November 2013

Predicting and Tracking Short Term Disease Progression in Amnestic Mild Cognitive Impairment Patients with Prodromal Alzheimer’s Disease: Structural Brain Biomarkers

scientific article published on 01 January 2019

Preventive study in subjects at risk of fatal familial insomnia: Innovative approach to rare diseases

scientific article

Quantitation of N-acetyl-aspartyl-glutamate in microdissected rat brain nuclei and peripheral tissues: findings with a novel liquid phase radioimmunoassay

scientific article published on 01 June 1988

Retro-inverso peptide inhibitor nanoparticles as potent inhibitors of aggregation of the Alzheimer's Aβ peptide

scientific article published on 18 October 2016

Review: PrP 106-126 - 25 years after

scientific article published on 03 February 2019

Role of Glycogen Synthase Kinase-3β in APP Hyperphosphorylation Induced by NMDA Stimulation in Cortical Neurons.

scientific article published on 7 January 2010

Role of neurodevelopment involved genes in psychiatric comorbidities and modulation of inflammatory processes in Alzheimer's disease.

scientific article published on 28 September 2016

Secretome released from hydrogel-embedded adipose mesenchymal stem cells protects against the Parkinson's disease related toxin 6-hydroxydopamine

scientific article

Selective nanovector mediated treatment of activated proinflammatory microglia/macrophages in spinal cord injury.

scientific article published on 18 October 2013

Single severe traumatic brain injury produces progressive pathology with ongoing contralateral white matter damage one year after injury.

scientific article published on 7 November 2017

Sirtuin 2 Inhibition Improves Cognitive Performance and Acts on Amyloid-β Protein Precursor Processing in Two Alzheimer's Disease Mouse Models

scientific article published on 30 June 2016

Somatostatin expression in TS16 mouse brain cultures

scientific article published on April 1, 1998

Sporadic human prion diseases: molecular insights and diagnosis

scientific article published on July 1, 2012

Stem cell paracrine effect and delivery strategies for spinal cord injury regeneration

scientific article published on 06 March 2019

Stress impairs synaptic plasticity in triple-transgenic Alzheimer's disease mice: rescue by ryanodine

scientific article

Striatum and entorhinal cortex atrophy in AD mouse models: MRI comprehensive analysis.

scientific article published on 25 October 2014

Studies on the indirect feedback inhibition of cholinergic neurons triggered by oxotremorine in striatum

scientific article published on November 23, 1981

Synthesis and evaluation of a (18)F-curcumin derivate for β-amyloid plaque imaging.

scientific article published on 18 March 2014

The Anti-Prion Antibody 15B3 Detects Toxic Amyloid-β Oligomers

scientific article published on 06 July 2016

The Continuing Failure of Bexarotene in Alzheimer's Disease Mice.

scientific article

The Parkinson's disease-related protein DJ-1 protects dopaminergic neurons in vivo and cultured cells from alpha-synuclein and 6-hydroxydopamine toxicity.

scientific article published on 11 December 2014

The neurodegeneration in Alzheimer disease and the prion protein

scientific article published on January 2013

The role of single-nucleotide variants of the energy metabolism-linked genes SIRT3, PPARGC1A and APOE in amyotrophic lateral sclerosis risk.

scientific article

The serotonin transporter and the activity regulated cytoskeleton-associated protein genes in antidepressant response and resistance: 5-HTTLPR and other variants

scientific article published on 13 November 2018

Toll-like receptor 4-dependent glial cell activation mediates the impairment in memory establishment induced by β-amyloid oligomers in an acute mouse model of Alzheimer's disease.

scientific article published on 14 October 2016

Tunable hydrogel-nanoparticles release system for sustained combination therapies in the spinal cord.

scientific article

Two-Year Longitudinal Monitoring of Amnestic Mild Cognitive Impairment Patients with Prodromal Alzheimer's Disease Using Topographical Biomarkers Derived from Functional Magnetic Resonance Imaging and Electroencephalographic Activity

scientific article published on 01 January 2019

c-Jun N-terminal Kinase Regulates Soluble Aβ Oligomers and Cognitive Impairment in AD Mouse Model

scientific article published on October 27, 2011

miR-146a and miR-181a are involved in the progression of mild cognitive impairment to Alzheimer's disease

scientific article published on 21 June 2019