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List of works by Wado Akamatsu

A Cell-Based High-Throughput Screening Identified Two Compounds that Enhance PINK1-Parkin Signaling

scientific article published on 11 April 2020

A human Dravet syndrome model from patient induced pluripotent stem cells

scientific article published on 2 May 2013

A progressive and cell non-autonomous increase in striatal neural stem cells in the Huntington's disease R6/2 mouse.

scientific article

Assessment of Mitophagy in iPS Cell-Derived Neurons

scientific article published on 01 January 2018

Astrocytes Protect Human Dopaminergic Neurons from α-Synuclein Accumulation and Propagation

scientific article published on 12 October 2020

BRUP-1, an intracellular bilirubin modulator, exerts neuroprotective activity in a cellular Parkinson's disease model

scientific article published on 03 March 2020

Brief exposure to small molecules allows induction of mouse embryonic fibroblasts into neural crest-like precursors

scientific article

CHARGE syndrome modeling using patient-iPSCs reveals defective migration of neural crest cells harboring CHD7 mutations.

scientific article published on 28 November 2017

Cell-specific overexpression of COMT in dopaminergic neurons of Parkinson's disease

scientific article published on 01 June 2019

Changeability of the fully methylated status of the 15q11.2 region in induced pluripotent stem cells derived from a patient with Prader-Willi syndrome

scientific article published on 21 December 2016

Chemical decontamination of iPS cell-derived neural cell mixtures.

scientific article published on 19 January 2018

Cochlear Cell Modeling Using Disease-Specific iPSCs Unveils a Degenerative Phenotype and Suggests Treatments for Congenital Progressive Hearing Loss.

scientific article published in January 2017

Controlling the Regional Identity of hPSC-Derived Neurons to Uncover Neuronal Subtype Specificity of Neurological Disease Phenotypes

scientific article published on 4 November 2015

Correction: The RNA-binding protein HuD regulates autophagosome formation in pancreatic β cells by promoting autophagy-related gene 5 expression

scientific article published on 01 September 2020

Derivation of Induced Pluripotent Stem Cells by Retroviral Gene Transduction in Mammalian Species ⬇️

scientific article published on January 1, 2012

Differential X Chromosome Inactivation Patterns during the Propagation of Human Induced Pluripotent Stem Cells

scientific article published on 20 January 2017

Differential gene expression profiles in neurons generated from lymphoblastoid B-cell line-derived iPS cells from monozygotic twin cases with treatment-resistant schizophrenia and discordant responses to clozapine.

scientific article published on 27 October 2016

Differentiation of multipotent neural stem cells derived from Rett syndrome patients is biased toward the astrocytic lineage

scientific article published on 27 May 2015

Direct reprogramming of somatic cells into neural cell lineages

scientific article published on 01 June 2015

Down-regulation of ghrelin receptors on dopaminergic neurons in the substantia nigra contributes to Parkinson's disease-like motor dysfunction

scientific article published on 20 February 2018

Efficient induction of dopaminergic neuron differentiation from induced pluripotent stem cells reveals impaired mitophagy in PARK2 neurons

scientific article published on 2 January 2017

Enhanced aggregation of androgen receptor in induced pluripotent stem cell-derived neurons from spinal and bulbar muscular atrophy

scientific article published on 30 January 2013

Erratum: Investigation of the fatty acid transporter-encoding genes SLC27A3 and SLC27A4 in autism.

scientific article published on 29 January 2016

Escape from Pluripotency via Inhibition of TGF-β/BMP and Activation of Wnt Signaling Accelerates Differentiation and Aging in hPSC Progeny Cells

scientific article published on 24 October 2017

Establishment of In Vitro FUS-Associated Familial Amyotrophic Lateral Sclerosis Model Using Human Induced Pluripotent Stem Cells.

scientific article published on 16 March 2016

Establishment of induced pluripotent stem cells from centenarians for neurodegenerative disease research

scientific article

Evidence that phosphorylated ubiquitin signaling is involved in the etiology of Parkinson's disease.

scientific article published on 25 May 2017

Exploring the neural diseases using stem cell technology ⬇️

scientific article published on 01 January 2012

Functional Neurons Generated from T Cell-Derived Induced Pluripotent Stem Cells for Neurological Disease Modeling

scientific article published on 9 February 2016

Generation of human melanocytes from induced pluripotent stem cells

scientific article

Generation of human melanocytes from induced pluripotent stem cells

scientific article published in January 2013

Generation of neural cells using iPSCs from sleep bruxism patients with 5-HT2A polymorphism.

scientific article published in December 2016

Generation of the induced pluripotent stem cell (hiPSC) line (JUFMDOi004-A) from a patient with hearing loss carrying GJB2 (p.V37I) mutation

scientific article published on 04 December 2019

Generation of two induced pluripotent stem cell lines from PBMCs of siblings carrying c.235delC mutation in the GJB2 gene associated with sensorineural hearing loss

scientific article published on 19 July 2020

Human Decidua-Derived Mesenchymal Cells Are a Promising Source for the Generation and Cell Banking of Human Induced Pluripotent Stem Cells

scientific article published on November 2012

Human induced pluripotent stem cell-derived ectodermal precursor cells contribute to hair follicle morphogenesis in vivo

scientific article published on 15 January 2013

I2020T mutant LRRK2 iPSC-derived neurons in the Sagamihara family exhibit increased Tau phosphorylation through the AKT/GSK-3β signaling pathway

scientific article published on 8 June 2015

Identifying Therapeutic Agents for Amelioration of Mitochondrial Clearance Disorder in Neurons of Familial Parkinson Disease

scientific article published on 14 May 2020

In vitro characterization of neurite extension using induced pluripotent stem cells derived from lissencephaly patients with TUBA1A missense mutations

scientific article

Increased Lysosomal Exocytosis Induced by Lysosomal Ca2+ Channel Agonists Protects Human Dopaminergic Neurons from α-Synuclein Toxicity

scientific article published on 16 May 2019

Increased l1 retrotransposition in the neuronal genome in schizophrenia

scientific article

Induced Pluripotent Stem Cells Reprogrammed with Three Inhibitors Show Accelerated Differentiation Potentials with High Levels of 2-Cell Stage Marker Expression

Investigation of the fatty acid transporter-encoding genes SLC27A3 and SLC27A4 in autism

scientific article

Involvement of ER Stress in Dysmyelination of Pelizaeus-Merzbacher Disease with PLP1 Missense Mutations Shown by iPSC-Derived Oligodendrocytes.

scientific article

Involvement of ER stress in dysmyelination of Pelizaeus-Merzbacher Disease with PLP1 missense mutations shown by iPSC-derived oligodendrocytes

scientific article

LNGFR+THY-1+ human pluripotent stem cell-derived neural crest-like cells have the potential to develop into mesenchymal stem cells

scientific article published on 10 May 2016

Mitochondrial dysfunction associated with increased oxidative stress and α-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue

scientific article published on 6 October 2012

Modeling Rett Syndrome Using Human Induced Pluripotent Stem Cells

scientific article published on 13 April 2016

Modeling familial Alzheimer's disease with induced pluripotent stem cells

scientific article published on 7 September 2011

Modeling familial Alzheimer's disease with induced pluripotent stem cells

scientific article published in January 2012

Modeling neurological diseases with induced pluripotent cells reprogrammed from immortalized lymphoblastoid cell lines

scientific article published on 03 October 2016

Mutations in CHCHD2 cause α-synuclein aggregation

scientific article published on 01 December 2019

Neural differentiation from induced pluripotent stem cells for disease modelling and drug discovery

scientific article published in January 2017

Neural stem cells directly differentiated from partially reprogrammed fibroblasts rapidly acquire gliogenic competency

scientific article published on 01 June 2012

Neuroprotective effects of memantine via enhancement of autophagy

scientific article published on 17 August 2019

PM492. Schizophrenia patient-derived induced pluripotent stem cells exhibit changes in neurogenic and gliogenic competences.

scientific article published on 27 May 2016

Pathophysiological analysis of Parkinson's disease using iPS cells

scientific article published on 01 June 2015

Pathophysiological analysis of Parkinson's disease using iPS cells

scientific article published in June 2015

Prenatal deletion of the RNA-binding protein HuD disrupts postnatal cortical circuit maturation and behavior

scientific journal article

RNA-Binding Protein HuD Controls Insulin Translation

scientific article published on 01 December 2020

RNA-binding protein HuD controls insulin translation

scientific article published in March 2012

Regeneration of the damaged central nervous system through reprogramming technology: basic concepts and potential application for cell replacement therapy

scientific article published on October 2012

Reprogramming non-human primate somatic cells into functional neuronal cells by defined factors

scientific article published on 3 April 2014

Rostrocaudal Areal Patterning of Human PSC-Derived Cortical Neurons by FGF8 Signaling.

scientific article

Soluble epoxide hydrolase plays a key role in the pathogenesis of Parkinson's disease

scientific article published on 07 May 2018

Suppression of Oct4 by germ cell nuclear factor restricts pluripotency and promotes neural stem cell development in the early neural lineage.

scientific article published in February 2009

The RNA-binding protein HuD regulates autophagosome formation in pancreatic β cells by promoting autophagy-related gene 5 expression

scientific article

The RNA-binding protein HuD regulates neuronal cell identity and maturation.

scientific article

The use of induced pluripotent stem cells to reveal pathogenic gene mutations and explore treatments for retinitis pigmentosa.

scientific article

Translational derepression of Elavl4 isoforms at their alternative 5' UTRs determines neuronal development

scientific article published on 03 April 2020

Utility of Scalp Hair Follicles as a Novel Source of Biomarker Genes for Psychiatric Illnesses.

scientific article published on 11 September 2014

Variants in saposin D domain of prosaposin gene linked to Parkinson's disease

scientific article published on 23 March 2020

Zonisamide Administration Improves Fatty Acid β-Oxidation in Parkinson's Disease

scientific article published on 29 December 2018

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