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List of works by Piotr Hadaczek

Adeno-associated viral vector serotype 9-based gene therapy for Niemann-Pick disease type A

scientific article published on 01 August 2019

Anterograde axonal transport of AAV2-GDNF in rat basal ganglia

scientific article published on 23 November 2010

Basic fibroblast growth factor enhances transduction, distribution, and axonal transport of adeno-associated virus type 2 vector in rat brain

scientific article

Cerebral infusion of AAV9 vector-encoding non-self proteins can elicit cell-mediated immune responses

scientific article

Clinically relevant effects of convection-enhanced delivery of AAV2-GDNF on the dopaminergic nigrostriatal pathway in aged rhesus monkeys

scientific article published on May 2009

Controlled dissemination of AAV vectors in the primate brain

scientific article

Convection-enhanced delivery of adeno-associated virus type 2 (AAV2) into the striatum and transport of AAV2 within monkey brain

scientific article published in March 2006

Cytogenetic and molecular findings in 75 clear cell renal cell carcinomas

scientific article published on 01 May 2005

DIPG-23. EFFICACY OF THE SOLUBLE PANOBINOSTAT (MTX110) IN PRECLINICAL DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) MODELS

scientific article published on 23 April 2019

Distribution of acid sphingomyelinase in rodent and non-human primate brain after intracerebroventricular infusion.

scientific article published on 14 July 2011

Distribution of nanoparticles throughout the cerebral cortex of rodents and non-human primates: Implications for gene and drug therapy

scientific article published on 17 March 2014

Efficient gene therapy-based method for the delivery of therapeutics to primate cortex

scholarly article

Eight years of clinical improvement in MPTP-lesioned primates after gene therapy with AAV2-hAADC.

scientific article

Evaluation of an AAV2-Based Rapamycin-Regulated Glial Cell Line-Derived Neurotrophic Factor (GDNF) Expression Vector System ⬇️

scientific article published on November 21, 2011

Extensive Transduction and Enhanced Spread of a Modified AAV2 Capsid in the Non-human Primate CNS

scientific article published on 12 July 2018

Extensive distribution of liposomes in rodent brains and brain tumors following convection-enhanced delivery.

scientific article

GDNF signaling implemented by GM1 ganglioside; failure in Parkinson's disease and GM1-deficient murine model

scientific article

Ganglioside Metabolism and Parkinson's Disease

scientific article published on 5 February 2018

Human interleukin-10 gene transfer is protective in a rat model of Parkinson's disease

scientific article published on 10 June 2008

Image-guided convection-enhanced delivery of GDNF protein into monkey putamen

scientific article

Kinetics and MR-Based Monitoring of AAV9 Vector Delivery into Cerebrospinal Fluid of Nonhuman Primates

scientific article published on 08 December 2018

Limited efficacy of gene transfer in herpes simplex virus-thymidine kinase/ganciclovir gene therapy for brain tumors.

scientific article published on February 2005

Non-PEGylated liposomes for convection-enhanced delivery of topotecan and gadodiamide in malignant glioma: initial experience.

scientific article published on 24 May 2009

Pharmacokinetics and bioactivity of glial cell line-derived factor (GDNF) and neurturin (NTN) infused into the rat brain

scientific article

Pharmacokinetics, tumor accumulation and antitumor activity of nanoliposomal irinotecan following systemic treatment of intracranial tumors.

scientific article

Real-time MR imaging of adeno-associated viral vector delivery to the primate brain

scientific article

Real-time MR imaging with Gadoteridol predicts distribution of transgenes after convection-enhanced delivery of AAV2 vectors

scientific article

Regeneration of the MPTP-lesioned dopaminergic system after convection-enhanced delivery of AAV2-GDNF.

scientific article

SAFETY AND TOLERABILITY OF MRI-GUIDED INFUSION OF AAV2-hAADC INTO THE MID-BRAIN OF NON-HUMAN PRIMATE.

scientific article

Safety evaluation of AAV2-GDNF gene transfer into the dopaminergic nigrostriatal pathway in aged and parkinsonian rhesus monkeys

scientific article

Systemic rapamycin alone may not be a treatment option for malignant glioma: evidence from an in vivo study ⬇️

scientific article published on February 17, 2012

The "perivascular pump" driven by arterial pulsation is a powerful mechanism for the distribution of therapeutic molecules within the brain

scientific article published on 02 May 2006

The influence of AAV2-mediated gene transfer of human IL-10 on neurodegeneration and immune response in a murine model of Parkinson's disease

scientific article published on 8 April 2014

Transduction of nonhuman primate brain with adeno-associated virus serotype 1: vector trafficking and immune response

scientific article published on March 2009

Validation of antibodies for neuroanatomical localization of the P2Y11 receptor in macaque brain.

scientific article published on 8 August 2016

Widespread AAV1- and AAV2-mediated transgene expression in the nonhuman primate brain: implications for Huntington's disease

scientific article published on 29 June 2016

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