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List of works by John B. Harley

46,X,del(X)(q13) Turner's syndrome women with systemic lupus erythematosus in a pedigree multiplex for SLE.

scientific article published on 21 May 2009

60 kD Ro and nRNP A frequently initiate human lupus autoimmunity.

scientific article

A GWAS Study on Liver Function Test Using eMERGE Network Participants

scientific article published on 28 September 2015

A Limited Lupus Anti-Spliceosomal Response Targets a Cross-Reactive, Proline-Rich Motif ⬇️

scientific article published on 01 October 1998

A candidate region on 11p13 for systemic lupus erythematosus: a linkage identified in African-American families

scientific article

A common autoepitope near the carboxyl terminus of the 60-kD Ro ribonucleoprotein: Sequence similarity with a viral protein ⬇️

scientific article published on November 1, 1991

A comprehensive analysis of shared loci between systemic lupus erythematosus (SLE) and sixteen autoimmune diseases reveals limited genetic overlap

scientific article

A distinctive autoantibody profile in black female patients with lupus nephritis

scientific article published on 01 November 1993

A functional haplotype of UBE2L3 confers risk for systemic lupus erythematosus

scientific article

A functional variant in FCRL3, encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities

scientific article

A genetic marker within the CD44 gene confirms linkage at 11p13 in African-American families with lupus stratified by thrombocytopenia, but genetic association with CD44 is not present

scientific article

A genome screen of systemic lupus erythematosus using affected-relative-pair linkage analysis with covariates demonstrates genetic heterogeneity

article

A genome-wide integrative genomic study localizes genetic factors influencing antibodies against Epstein-Barr virus nuclear antigen 1 (EBNA-1).

scientific article

A hypothesis for the HLA-B27 immune dysregulation in spondyloarthropathy: contributions from enteric organisms, B27 structure, peptides bound by B27, and convergent evolution

scientific article published on October 1993

A model for disease heterogeneity in systemic lupus erythematosus. Relationships between histocompatibility antigens, autoantibodies, and lymphopenia or renal disease

scientific article published on 01 July 1989

A nonsynonymous functional variant in integrin-αM (encoded by ITGAM) is associated with systemic lupus erythematosus

article

A plausibly causal functional lupus-associated risk variant in the STAT1-STAT4 locus

scholarly article by Zubin Patel published in April 2018

A polymorphism within IL21R confers risk for systemic lupus erythematosus

scientific article published on August 2009

A regulatory polymorphism in PDCD1 is associated with susceptibility to systemic lupus erythematosus in humans

scientific article (publication date: December 2002)

A shared idiotype among human anti-Ro/SSA autoantibodies

scientific article

A subset of hY RNAs is associated with erythrocyte Ro ribonucleoproteins ⬇️

scientific article published on November 1, 1990

ABIN1 dysfunction as a genetic basis for lupus nephritis

scientific article published on 22 August 2013

Aberrant Epstein-Barr viral infection in systemic lupus erythematosus

scientific article

Addressing genetic heterogeneity in complex disease: finding seizure genes in systemic lupus erythematosus

scientific article published on 6 December 2007

Admixture in Hispanic Americans: its impact on ITGAM association and implications for admixture mapping in SLE.

scientific article published on 23 April 2009

Admixture mapping in lupus identifies multiple functional variants within IFIH1 associated with apoptosis, inflammation, and autoantibody production

scientific article

Age- and sex-related patterns of serum interferon-alpha activity in lupus families

scientific article published on July 2008

Allelic heterogeneity in NCF2 associated with systemic lupus erythematosus (SLE) susceptibility across four ethnic populations

scientific article published on 26 October 2013

Altered type II interferon precedes autoantibody accrual and elevated type I interferon activity prior to systemic lupus erythematosus classification

scientific article

Amino acid signatures of HLA Class-I and II molecules are strongly associated with SLE susceptibility and autoantibody production in Eastern Asians

article

An altered immune response to Epstein-Barr nuclear antigen 1 in pediatric systemic lupus erythematosus

scientific article published in January 2006

An increased prevalence of Epstein-Barr virus infection in young patients suggests a possible etiology for systemic lupus erythematosus ⬇️

scientific article published on December 15, 1997

Analysis of autosomal genes reveals gene-sex interactions and higher total genetic risk in men with systemic lupus erythematosus

scientific article published on 21 November 2011

Analysis of maternal-offspring HLA compatibility, parent-of-origin effects, and noninherited maternal antigen effects for HLA-DRB1 in systemic lupus erythematosus

scientific article

Anthrax vaccination induced anti-lethal factor IgG: Fine specificity and neutralizing capacity ⬇️

scientific article published on March 21, 2011

Anti-La/SSB antibody is present in some normal sera and is coincident with anti-Ro/SSA precipitins in systemic lupus erythematosus

scientific article published on 01 June 1984

Anti-Ro (SS-A) and anti-La (SS-B) in patients with Sjögren's syndrome

scientific article published on 01 February 1986

Anti-Ro (SS-A) antibodies from Ro (SS-A)-immunized mice

scientific article published on 01 February 1988

Anti-Ro and anti-nRNP response in unaffected family members of SLE patients

scientific article published on 01 January 2003

Anti-Ro autoantibody with cross-reactive binding to the heavy chain of immunoglobulin G ⬇️

scientific article published on July 1, 1992

Anti-Ro fine specificity defined by multiple antigenic peptides identifies components of tertiary epitopes ⬇️

scientific article published on September 1, 1997

Anti-Ro in Sjögren's syndrome and systemic lupus erythematosus

scientific article published on May 1, 1992

Anti-Ro(SS-A) autoantibodies in central nervous system disease associated with Sjögren's syndrome (CNS-SS): clinical, neuroimaging, and angiographic correlates

scientific article published in May 1994

Anti-Ro(SSA) autoantibodies are associated with T cell receptor beta genes in systemic lupus erythematosus patients

scientific article

Anti-Ro/SS-a positivity and heat shock protein antibodies in patients with normal-pressure glaucoma ⬇️

scientific article published on 01 February 1998

Anti-centromere autoantibody in a patient evolving from a lupus/Sjögren's overlap to the CREST variant of scleroderma

scientific article published on July 1, 1998

Anti-neutrophil cytoplasmic antibodies target sequential functional proteinase 3 epitopes in the sera of patients with Wegener's granulomatosis ⬇️

scientific article published on November 1, 2010

Antibodies to Ro(SSA) and the heterogeneity of systemic lupus erythematosus

scientific article published on 01 June 1987

Antibodies to vesicular stomatitis virus proteins in patients with systemic lupus erythematosus and in normal subjects

scientific article published in July 1993

Antigenicity of a recombinant Ro (SS-A) fusion protein ⬇️

scientific article published on January 1, 1990

Antinuclear autoantibodies in systemic lupus erythematosus

scientific article published in September 2004

Association of PPP2CA polymorphisms with systemic lupus erythematosus susceptibility in multiple ethnic groups

scientific article

Association of a functional IRF7 variant with systemic lupus erythematosus

scientific article

Association of a functional variant downstream of TNFAIP3 with systemic lupus erythematosus

scientific article

Association of anti-Ro/SS-A autoantibodies with glutamine in position 34 of DQA1 and leucine in position 26 of DQB1

scientific article published on 01 June 1994

Association of common variants in the human eyes shut ortholog (EYS) with statin‐induced myopathy: Evidence for additional functions of EYS ⬇️

scientific article published on August 8, 2011

Association of dry eyes and dry mouth with anti-Ro/SS-A and anti-La/SS-B autoantibodies in normal adults

scientific article published on December 1, 1992

Association of genetic variants in complement factor H and factor H-related genes with systemic lupus erythematosus susceptibility

scientific article

Association of hY4 pseudogenes with Alu repeats and abundance of hY RNA-like sequences in the human genome

scientific article published on July 15, 1992

Association of systemic lupus erythematosus with uranium exposure in a community living near a uranium-processing plant: a nested case-control study

scientific article

Association of the G-463A myeloperoxidase gene polymorphism with renal disease in African Americans with systemic lupus erythematosus.

scientific article

Association of the IRF5 risk haplotype with high serum interferon-alpha activity in systemic lupus erythematosus patients

scientific article published on August 2008

Association of two independent functional risk haplotypes in TNIP1 with systemic lupus erythematosus

scientific article

Autoantibodies

scientific article

Autoantibodies are central to the diagnosis and clinical manifestations of lupus

scientific article published on 01 July 1994

Autoantibodies in Sjögren's syndrome

scientific article

Autoantibodies targeting glomerular annexin A2 identify patients with proliferative lupus nephritis

scientific article

Autoantibody prevalence and lupus characteristics in a unique African American population

scientific article published in May 2008

Autoantigenicity of Ro/SSA antigen is related to a nucleocapsid protein of vesicular stomatitis virus ⬇️

scientific article published on April 15, 1991

Autoepitopes in lupus.

scientific article published on December 1995

Autoimmune response to the Ro/SSA particle is directed to the human antigen

article

Autoimmune thyroid disease is associated with a diagnosis of secondary Sjögren's syndrome in familial systemic lupus

scientific article published on 19 September 2006

Autoimmunity and Klinefelter's syndrome: when men have two X chromosomes

scientific article

Autoimmunity as a result of escape from RNA surveillance

scientific article

Basic amino acids predominate in the sequential autoantigenic determinants of the small nuclear 70K ribonucleoprotein

scientific article published on 01 June 1994

Biology-Driven Gene-Gene Interaction Analysis of Age-Related Cataract in the eMERGE Network

scientific article

CTLA-4 polymorphisms and systemic lupus erythematosus (SLE): a meta-analysis

article

Cerebral vasculopathy associated with collateralization resembling moya moya phenomenon and with anti-Ro/SS-A and anti-La/SS-B antibodies

scientific article published in August 1991

Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus

scientific article

Characterization and classification of lupus patients based on plasma thermograms

scientific article published on 17 November 2017

Characterization and genomic sequence of the murine 60 kD Ro gene

scientific article

Characterization of human telomerase complex.

scientific article published on September 1997

Characterization of human-human hybridoma monoclonal anti-Ro(SS-A) autoantibodies derived from normal tonsil lymphoid cells

scientific article published on December 1992

Clinical and serological features distinguish patients with incomplete lupus classification from systemic lupus erythematosus patients and controls

scientific article published on 24 January 2017

Clinical criteria for systemic lupus erythematosus precede diagnosis, and associated autoantibodies are present before clinical symptoms

scientific article published on July 2007

Combined protein- and nucleic acid-level effects of rs1143679 (R77H), a lupus-predisposing variant within ITGAM

scientific article

Combined role of vitamin D status and CYP24A1 in the transition to systemic lupus erythematosus

scientific article published on 9 June 2016

Common variants within MECP2 confer risk of systemic lupus erythematosus

scientific article

Comparison of autoantibody specificities between traditional and bead-based assays in a large, diverse collection of patients with systemic lupus erythematosus and family members

scientific article

Comparison of the American-European Consensus Group Sjogren's syndrome classification criteria to newly proposed American College of Rheumatology criteria in a large, carefully characterised sicca cohort

scientific article

Complement C4 fixation by the anti-La(SSB) found in normal donors and in patients with systemic lupus erythematosus

scientific article published on 01 February 1986

Complement receptor 2 polymorphisms associated with systemic lupus erythematosus modulate alternative splicing

scientific article published on 23 April 2009

Complete congenital heart block followed by anti-Ro/SSA in adult life. Studies of an informative family

scientific article published on 01 February 1988

Confirmation of genetic linkage between human systemic lupus erythematosus and chromosome 1q41.

scientific article published on September 1999

Conserved features of Y RNAs revealed by automated phylogenetic secondary structure analysis

scientific article published on February 1999

Conserved features of Y RNAs: a comparison of experimentally derived secondary structures

scientific article

Cooperative association of T cell beta receptor and HLA-DQ alleles in the production of anti-Ro in systemic lupus erythematosus

scientific article published on September 1994

Corrigendum to "Klinefelter's syndrome (47,XXY) is in excess among men with Sjögren's syndrome" [Clin. Immunol. 168 (2016) 25-29].

scientific article published on 28 November 2017

Current status of lupus genetics

scientific article

DNA repair in lupus

scientific article published on 18 September 2014

Decreased SMG7 expression associates with lupus-risk variants and elevated antinuclear antibody production

scientific article published on 18 January 2016

Delineation of the human systemic lupus erythematosus anti-Smith antibody response using phage-display combinatorial libraries

scientific article

Detection by ELISA of antibodies to small RNA protein particles in systemic lupus erythematosus patients whose sera lack precipitins

scientific article published on 01 January 1986

Developing an Algorithm to Detect Early Childhood Obesity in Two Tertiary Pediatric Medical Centers

scientific article published on 20 July 2016

Development of anti-dsDNA autoantibodies prior to clinical diagnosis of systemic lupus erythematosus

scientific article published on 01 July 2001

Development of the anti-Ro autoantibody response in a patient with systemic lupus erythematosus

scientific article published on 01 October 1996

Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production

scientific article

Discerning Risk of Disease Transition in Relatives of Systemic Lupus Erythematosus Patients Utilizing Soluble Mediators and Clinical Features.

scientific article published on 18 November 2016

Dual effect of the macrophage migration inhibitory factor gene on the development and severity of human systemic lupus erythematosus

scientific article published on December 2011

Dysregulation of innate and adaptive serum mediators precedes systemic lupus erythematosus classification and improves prognostic accuracy of autoantibodies

scientific article published on 20 June 2016

EMR-linked GWAS study: investigation of variation landscape of loci for body mass index in children

scientific article published on 03 December 2013

Early disease onset is predicted by a higher genetic risk for lupus and is associated with a more severe phenotype in lupus patients

scientific article

Early events in lupus humoral autoimmunity suggest initiation through molecular mimicry

scientific article

Early targets of nuclear RNP humoral autoimmunity in human systemic lupus erythematosus

scientific article

Editorial for Lindop et al. “Long-term Ro60 humoral autoimmunity in primary Sjögren's syndrome is maintained by rapid clonal turnover” ⬇️

scientific article published on April 30, 2013

Editorial: What caused all these troubles, anyway? Epstein-Barr virus in Sjögren's syndrome reevaluated

scientific article published on September 2014

Effects of IRF5 lupus risk haplotype on pathways predicted to influence B cell functions

scientific article published on 22 February 2012

Electronic Health Record Based Algorithm to Identify Patients with Autism Spectrum Disorder

scientific article published on 29 July 2016

End-stage renal disease in African Americans with lupus nephritis is associated with APOL1

scientific article published on February 2014

Epstein-Barr virus and molecular mimicry in systemic lupus erythematosus

scientific article

Epstein-Barr virus and systemic lupus erythematosus

scientific article

Epstein-Barr virus infection induces lupus autoimmunity.

scientific article published on January 2006

Epstein-Barr virus infection may be an environmental risk factor for systemic lupus erythematosus in children and teenagers

scientific article published in August 1999

Erratum: Complement receptor 2 polymorphisms associated with systemic lupus erythematosus modulate alternative splicing

article

Erratum: Genetic associations of LYN with systemic lupus erythematosus

article

European population substructure is associated with mucocutaneous manifestations and autoantibody production in systemic lupus erythematosus

scientific article published on August 2009

Evaluation of C1q genomic region in minority racial groups of lupus

scientific article published on 14 May 2009

Evaluation of TRAF6 in a large multiancestral lupus cohort

scientific article

Evaluation of genetic association between an ITGAM non-synonymous SNP (rs1143679) and multiple autoimmune diseases

scientific article published on 05 August 2011

Evaluation of imputation-based association in and around the integrin-alpha-M (ITGAM) gene and replication of robust association between a non-synonymous functional variant within ITGAM and systemic lupus erythematosus (SLE).

scientific article

Evaluation of the TREX1 gene in a large multi-ancestral lupus cohort

scientific article

Evaluation of the genetic association of thePTPN22 R620W polymorphism in familial and sporadic systemic lupus erythematosus

article

Everyone comes from somewhere: systemic lupus erythematosus and Epstein-Barr virus induction of host interferon and humoral anti-Epstein-Barr nuclear antigen 1 immunity

scientific article published on June 2010

Evidence for a susceptibility gene (SLEH1) on chromosome 11q14 for systemic lupus erythematosus (SLE) families with hemolytic anemia

scientific article

Evidence for a susceptibility gene, SLEV1, on chromosome 17p13 in families with vitiligo-related systemic lupus erythematosus

scientific article

Evidence for gene-gene epistatic interactions among susceptibility loci for systemic lupus erythematosus

scientific article published on February 2012

Evidence of dynamically dysregulated gene expression pathways in hyperresponsive B cells from African American lupus patients

scientific article

Excess female siblings and male fetal loss in families with systemic lupus erythematosus

scientific article published on February 2013

F.20. Delineating SLE Susceptibility Polymorphisms at the OX40L Locus

Familial aggregation and linkage analysis of autoantibody traits in pedigrees multiplex for systemic lupus erythematosus

article

Familial aggregation of high tumor necrosis factor alpha levels in systemic lupus erythematosus

scientific article published on 25 September 2013

Familial aggregation of lupus and autoimmunity in an unusual multiplex pedigree

scientific article published on 01 July 1999

Familial systemic lupus erythematosus: a comparison of clinical manifestations and antibody presentation in three ethnic groups

scientific article

Familiality and co-occurrence of clinical features of systemic lupus erythematosus

scientific article

Fine mapping of Xq28: both MECP2 and IRAK1 contribute to risk for systemic lupus erythematosus in multiple ancestral groups

scientific article published on 17 August 2012

Fine specificity of the autoimmune response to the Ro/SSA and La/SSB ribonucleoproteins

scientific article

Fine-mapping and transethnic genotyping establish IL2/IL21 genetic association with lupus and localize this genetic effect to IL21

scientific article

Focused transcription from the human CR2/CD21 core promoter is regulated by synergistic activity of TATA and Initiator elements in mature B cells

scientific article

Gene interaction at HLA-DQ enhances autoantibody production in primary Sjögren's syndrome

scientific article published in May 1986

Genes and Sjögren's syndrome

scientific article

Genes for murine Y1 and Y3 Ro RNAs have class 3 RNA polymerase III promoter structures and are unlinked on mouse chromosome 6.

scientific article published in September 1996

Genetic analyses of interferon pathway-related genes reveal multiple new loci associated with systemic lupus erythematosus

scientific article

Genetic ancestry, serum interferon-α activity, and autoantibodies in systemic lupus erythematosus

scientific article

Genetic and physical interaction of the B-cell systemic lupus erythematosus-associated genes BANK1 and BLK.

scientific article published on 6 October 2011

Genetic association between methyl-CpG binding protein 2 (MECP2) and primary Sjogren's syndrome

scientific article

Genetic association of CD247 (CD3ζ) with SLE in a large-scale multiethnic study.

scientific article

Genetic association of interleukin-21 polymorphisms with systemic lupus erythematosus

scholarly article by A H Sawalha et al published 2 August 2007 in Annals of the Rheumatic Diseases

Genetic associations of LYN with systemic lupus erythematosus

scientific article published on 16 April 2009

Genetic associations of leptin-related polymorphisms with systemic lupus erythematosus

scientific article

Genetic basis of systemic lupus erythematosus: a review of the unique genetic contributions in African Americans

scientific article

Genetic determinants of risk and survival in pulmonary arterial hypertension

article

Genetic fine mapping of systemic lupus erythematosus MHC associations in Europeans and African Americans

scholarly article by Ken B Hanscombe published in November 2018

Genetic linkage and association of Fc? receptor IIIA (CD16A) on chromosome 1q23 with human systemic lupus erythematosus

article

Genetic linkage of systemic lupus erythematosus to 13q32 in African American families with affected male members

scientific article published on 28 September 2005

Genetic linkage of systemic lupus erythematosus with chromosome 11q14 (SLEH1) in African-American families stratified by a nucleolar antinuclear antibody pattern

article

Genetic risk for malignant hyperthermia in non-anesthesia-induced myopathies ⬇️

scientific article published on July 12, 2011

Genetic studies of Ro (SS-A) and La (SS-B) autoantibodies in families with systemic lupus erythematosus and primary Sjögren's syndrome

scientific article

Genetic susceptibility to SLE: new insights from fine mapping and genome-wide association studies

scientific article published on May 2009

Genetic variation among 82 pharmacogenes: The PGRNseq data from the eMERGE network

scientific article

Genetic variation in the CRP promoter: association with systemic lupus erythematosus

scientific article

Genetically determined Amerindian ancestry correlates with increased frequency of risk alleles for systemic lupus erythematosus

scientific article

Genetics of clinical expression in SLE.

scientific article published on December 2007

Genetics of human systemic lupus erythematosus: the emerging picture

scientific article

Genetics of systemic lupus erythematosus: how far have we come?

scientific article

Genome scan of human systemic lupus erythematosus by regression modeling: evidence of linkage and epistasis at 4p16-15.2.

scientific article

Genome scan of human systemic lupus erythematosus: evidence for linkage on chromosome 1q in African-American pedigrees

scientific article (publication date: 8 December 1998)

Genome scan stratified by the presence of anti-double-stranded DNA (dsDNA) autoantibody in pedigrees multiplex for systemic lupus erythematosus (SLE) establishes linkages at 19p13.2 (SLED1) and 18q21.1 (SLED2)

article

Genome-Wide Association Study in an Amerindian Ancestry Population Reveals Novel Systemic Lupus Erythematosus Risk Loci and the Role of European Admixture

scientific article published on 25 November 2015

Genome-wide association analysis of eosinophilic esophagitis provides insight into the tissue specificity of this allergic disease

scientific article

Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci

scientific article

Genome-wide association scan of Dupuytren's disease

scientific article

Genome-wide association study identifies novel loci associated with diisocyanate-induced occupational asthma

journal article published in 2015

Genome-wide association study of African and European Americans implicates multiple shared and ethnic specific loci in sarcoidosis susceptibility

scientific article

Genome-wide linkage screen for stature and body mass index in 3.032 families: evidence for sex- and population-specific genetic effects

scientific article published on 10 September 2008

Genomic organization and polymorphisms of the human C3d/Epstein-Barr virus receptor

scientific article

HLA-B27 binding of peptide from its own sequence and similar peptides from bacteria: implications for spondyloarthropathies

scientific article published in June 1995

HLA-DQ gene complementation and other histocompatibility relationships in man with the anti-Ro/SSA autoantibody response of systemic lupus erythematosus

scientific article

Haemolytic anaemia in a multi-ethnic cohort of lupus patients: a clinical and serological perspective

scientific article

Heredity and systemic lupus erythematosus: dissecting a complex genetic disease

scientific article published on January 1, 1997

Heterogeneity of the Ro/SSA antigen. Different molecular forms in lymphocytes and red blood cells

scientific article

High serum IFN-alpha activity is a heritable risk factor for systemic lupus erythematosus

scientific article

High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions

scientific article published in October 2009

High-density genotyping of STAT4 reveals multiple haplotypic associations with systemic lupus erythematosus in different racial groups

scientific article published on April 2009

High-density genotyping of immune-related loci identifies new SLE risk variants in individuals with Asian ancestry

scientific article

Horizons in Sjögren's syndrome genetics

scientific article published on June 2007

Human anti-Ro autoantibodies bind multiple conformational epitopes of 60-kD Ro autoantigen

scientific article published on 01 May 1997

Human anti-Ro autoantibodies bind peptides accessible to the surface of the native Ro autoantigen

scientific article published on March 1995

Human autoantibody production in the severe combined immunodeficiency (scid) mouse

scientific article published on 01 March 1994

Human lupus anti-spliceosome A protein autoantibodies bind contiguous surface structures and segregate into two sequential epitope binding patterns.

scientific article published on May 1996

Human monoclonal antibodies reactive with antigens of the group A Streptococcus and human heart

scientific article

Humoral responses to independent vaccinations are correlated in healthy boosted adults

scientific article

Hydroxychloroquine sulfate treatment is associated with later onset of systemic lupus erythematosus

scientific article published on January 2007

IRF5 haplotypes demonstrate diverse serological associations which predict serum interferon alpha activity and explain the majority of the genetic association with systemic lupus erythematosus

scientific article

ITGAM coding variant (rs1143679) influences the risk of renal disease, discoid rash and immunological manifestations in patients with systemic lupus erythematosus with European ancestry

scientific article

Identification of ATPAF1 as a novel candidate gene for asthma in children

scientific article

Identification of Four Novel Loci in Asthma in European American and African American Populations

scientific article published on 9 September 2016

Identification of IFRD1 as a modifier gene for cystic fibrosis lung disease

scientific article

Identification of IRAK1 as a risk gene with critical role in the pathogenesis of systemic lupus erythematosus

scholarly article

Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as susceptibility loci for systemic lupus erythematosus in a large-scale multiracial replication study

scientific article published on 29 March 2012

Identification of a Systemic Lupus Erythematosus Risk Locus Spanning ATG16L2, FCHSD2, and P2RY2 in Koreans

scientific article published on 14 December 2015

Identification of a systemic lupus erythematosus susceptibility locus at 11p13 between PDHX and CD44 in a multiethnic study

scientific article

Identification of candidate loci at 6p21 and 21q22 in a genome-wide association study of cardiac manifestations of neonatal lupus

scientific article published on November 2010

Identification of microRNA-31 as a novel regulator contributing to impaired interleukin-2 production in T cells from patients with systemic lupus erythematosus.

scientific article

Identification of novel genetic susceptibility loci in African American lupus patients in a candidate gene association study

scientific article

Identification of unique microRNA signature associated with lupus nephritis

scientific article

Immune response to the RNA protein particles in systemic lupus erythematosus. A distinctive dichotomy

scientific article published on December 1988

Immunization of mice with human 60-kd Ro peptides results in epitope spreading if the peptides are highly homologous between human and mouse

scientific article published on 01 May 1999

Immunization with short peptides from the sequence of the systemic lupus erythematosus-associated 60-kDa Ro autoantigen results in anti-Ro ribonucleoprotein autoimmunity

scientific article published on 01 May 1996

Immunization with vesicular stomatitis virus nucleocapsid protein induces autoantibodies to the 60 kD Ro ribonucleoprotein particle

scientific article published on April 1995

Immunogenetics of epitopes of the carboxyl terminus of the human 60-kD Ro autoantigen

scientific article published on 01 February 1995

Immunoglobulin epitope spreading and autoimmune disease after peptide immunization: Sm B/B'-derived PPPGMRPP and PPPGIRGP induce spliceosome autoimmunity

scientific article

Immunologic and structural studies of the lupus/Sjögren's syndrome autoantigen, La/SSB, with a monoclonal antibody

scientific article

Impact of genetic ancestry and sociodemographic status on the clinical expression of systemic lupus erythematosus in American Indian-European populations

scientific article

Implications of anti-Ro/Sjögren's syndrome A antigen autoantibody in normal sera for autoimmunity

scientific article

Increased frequencies of Sm and nRNP autoantibodies in American blacks compared to whites with systemic lupus erythematosus

scientific article published on 01 December 1988

Increased prevalence of renal disease in systemic lupus erythematosus families with affected male relatives

scientific article published in February 2002

Induction of autoimmunity by multivalent immunodominant and subdominant T cell determinants of La (SS-B)

scientific article published on 01 March 1999

Infectious mononucleosis patients temporarily recognize a unique, cross‐reactive epitope of Epstein‐Barr virus nuclear antigen‐1 ⬇️

scientific article published on June 1, 2003

Interferon regulatory factor-5 is genetically associated with systemic lupus erythematosus in African Americans

article

Kallikrein genes are associated with lupus and glomerular basement membrane-specific antibody-induced nephritis in mice and humans

scientific article published on April 2009

Klinefelter's syndrome (47,XXY) in male systemic lupus erythematosus patients: support for the notion of a gene-dose effect from the X chromosome

scientific article

Klinefelter's syndrome (47,XXY) is in excess among men with Sjögren's syndrome

scientific article published on 21 April 2016

Klinefelter’s syndrome (47,XXY) among men with systemic lupus erythematosus ⬇️

scientific article published on March 7, 2011

Large-scale analysis of tumor necrosis factor α levels in systemic lupus erythematosus

scientific article

Latent autoimmunity across disease-specific boundaries in at-risk first-degree relatives of SLE and RA patients

Less than 7 hours of sleep per night is associated with transitioning to systemic lupus erythematosus

article by K A Young et al published August 2018 in Lupus

Linear epitope mapping of an Sm B/B' polypeptide ⬇️

scientific article published on 01 April 1992

Linkage analysis of SLE susceptibility: confirmation of SLER1 at 5p15.3.

scientific article published on May 2004

Linkage analysis of angiotensin-converting enzyme (ACE) insertion/deletion polymorphism and systemic lupus erythematosus

article

Linkage analysis of human systemic lupus erythematosus-related traits: A principal component approach ⬇️

scientific article published on 01 December 2001

Linkage at 12q24 with systemic lupus erythematosus (SLE) is established and confirmed in Hispanic and European American families

scientific article

Linkage at 5q14.3-15 in multiplex systemic lupus erythematosus pedigrees stratified by autoimmune thyroid disease

article

Localization and replication of the systemic lupus erythematosus linkage signal at 4p16: interaction with 2p11, 12q24 and 19q13 in European Americans

article

Logistic transmission modeling for the simulated data of GAW10 problem 2 ⬇️

scientific article published on January 1, 1997

Logistic transmission modeling of simulated data

scientific article published on January 1995

Lupus Risk Variant Increases pSTAT1 Binding and Decreases ETS1 Expression

scientific article

Lupus and interleukin 10

scientific article published on 01 December 1997

Lupus autoantibodies recognize the product of an alternative open reading frame of SmB/B'.

scientific article published on August 2001

Lupus humoral autoimmunity after short peptide immunization

scientific article published on 01 April 1997

Lupus humoral autoimmunity induced in a primate model by short peptide immunization

scientific article published on 01 February 1998

Lupus nephritis susceptibility loci in women with systemic lupus erythematosus

scientific article

Lupus risk variants in the PXK locus alter B-cell receptor internalization

scientific article

Lupus-associated causal mutation in neutrophil cytosolic factor 2 (NCF2) brings unique insights to the structure and function of NADPH oxidase

scientific article published on 27 December 2011

Lupus-like autoantibody development in rabbits and mice after immunization with EBNA-1 fragments

scientific article

Lupus/Sjögren's autoantibody specificities in sera with paraproteins

scientific article published on July 1987

MHC associations with clinical and autoantibody manifestations in European SLE.

scientific article

Mapping the systematic lupus erythematosus susceptibility genes

scientific article published in January 2004

Maternal antibodies to Ro (SS-A) are associated with both early onset of disease and male sex among children with systemic lupus erythematosus

scientific article published on 01 November 1989

Meta-analysis and imputation identifies a 109 kb risk haplotype spanning TNFAIP3 associated with lupus nephritis and hematologic manifestations

scientific article published on 23 April 2009

Meta-analysis of genome-wide linkage studies of systemic lupus erythematosus

scientific article published on 14 September 2006

MiR-125a targets effector programs to stabilize Treg-mediated immune homeostasis

scientific article published on 12 May 2015

MicroRNA-130b Ameliorates Murine Lupus Nephritis Through Targeting the Type I Interferon Pathway on Renal Mesangial Cells

scientific article published in September 2016

MicroRNA-3148 modulates allelic expression of toll-like receptor 7 variant associated with systemic lupus erythematosus

scientific article

Molecular analysis of the 60-kDa human Ro ribonucleoprotein

scientific article

Molecular properties of the Ro/SSA antigen and enzyme-linked immunosorbent assay for quantitation of antibody

scientific article published on August 1984

Monocyte MicroRNA Expression in Active Systemic Juvenile Idiopathic Arthritis Implicates MicroRNA-125a-5p in Polarized Monocyte Phenotypes

scientific article published on 25 March 2016

Multiple Autoantibodies Display Association with Lymphopenia, Proteinuria, and Cellular Casts in a Large, Ethnically Diverse SLE Patient Cohort

scientific article

Network analysis of associations between serum interferon-α activity, autoantibodies, and clinical features in systemic lupus erythematosus

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Noodling andMycobacterium marinuminfection mimicking seronegative rheumatoid arthritis complicated by anti–tumor necrosis factor α therapy ⬇️

scientific article published on January 1, 2011

OP0020 Identification of Multiple Sjögren’s Syndrome Susceptibility Loci

Oklahoma Choctaw and systemic sclerosis: the founder effect and genetic susceptibility

scientific article published on 01 October 1998

Osteopontin and systemic lupus erythematosus association: a probable gene-gender interaction

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PARP alleles and SLE: failure to confirm association with disease susceptibility

scientific article published on 01 June 2000

PTPN22 association in systemic lupus erythematosus (SLE) with respect to individual ancestry and clinical sub-phenotypes

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Pattern of cutaneous immunoglobulin G deposition in subacute cutaneous lupus erythematosus is reproduced by infusing purified anti-Ro (SSA) autoantibodies into human skin-grafted mice

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Pellet pestle homogenization of agarose gel slices at 45 degrees C for deoxyribonucleic acid extraction

scientific article published on 01 September 2001

Peptide Mimics of a Major Lupus Epitope of SmB/B′ ⬇️

scientific article published on April 1, 2003

Peptide autoantigenicity of the small nuclear ribonucleoprotein C

scientific article published on 01 May 1995

Phenome-wide association study (PheWAS) in EMR-linked pediatric cohorts, genetically links PLCL1 to speech language development and IL5-IL13 to Eosinophilic Esophagitis

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Phenotypic associations of genetic susceptibility loci in systemic lupus erythematosus

scientific article published on 30 June 2011

Polymorphisms in the Hsp70 gene locus are genetically associated with systemic lupus erythematosus

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Polymorphisms of complement receptor 1 and interleukin-10 genes and systemic lupus erythematosus: a meta-analysis

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Poststreptococcal anti-myosin antibody idiotype associated with systemic lupus erythematosus and Sjögren's syndrome

scientific article published on October 1993

Preferential association of a functional variant in complement receptor 2 with antibodies to double-stranded DNA.

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Preferential binding to Elk-1 by SLE-associated IL10 risk allele upregulates IL10 expression

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Presence of anti-La autoantibody is associated with a lower risk of nephritis and seizures in lupus patients

scientific article published in January 2007

Presence of anti-La(SS-B) is associated with binding to the 13-kD carboxyl terminus of 60-kD Ro(SS-A) in systemic lupus erythematosus

scientific article published on 01 April 1993

Protein-protein interaction of the Ro-ribonucleoprotein particle using multiple antigenic peptides

scientific article published on 01 October 1999

Rapid clinical progression to diagnosis among African-American men with systemic lupus erythematosus

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Rare X chromosome abnormalities in systemic lupus erythematosus and Sjögren's syndrome

scientific article published on 10 July 2017

Recent insights into the genetic basis of systemic lupus erythematosus

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Replication of the BANK1 genetic association with systemic lupus erythematosus in a European-derived population

scientific article published on 02 April 2009

Rheumatoid arthritis in a United States Public Health Service Hospital in Oklahoma: serologic manifestations in rheumatoid arthritis vary among tribal groups

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Rheumatoid factors from patients with rheumatoid arthritis react with tryptophan 60 and 95, lysine 58, and arginine 97, on human β2‐microglobulin ⬇️

scientific article published on 01 July 1993

Rheumatoid hyperviscosity: analysis of a patient with intermediate complexes that block other autoantibodies and a review of the literature ⬇️

scientific article published on June 1, 1998

Ribosomal P autoantibodies are present before SLE onset and are directed against non-C-terminal peptides

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Risk alleles for systemic lupus erythematosus in a large case-control collection and associations with clinical subphenotypes

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Ro (SS-A) antibody and antigen in a patient with congenital complete heart block

scientific article published on December 1985

Ro(SS-A) positive Sjogren's/lupus erythematosus (SC/LE) overlap patients are associated with the HLA-DR3 and/or DRw6 phenotypes

scientific article published in October 1988

Role of MYH9 and APOL1 in African and non-African populations with lupus nephritis

scientific article published on 22 December 2011

Role of viruses in systemic lupus erythematosus and Sjögren syndrome

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SLEB3 in systemic lupus erythematosus (SLE) is strongly related to SLE families ascertained through neuropsychiatric manifestations

scholarly article by Swapan K. Nath et al published July 2002 in Human Genetics

SLEN2 (2q34-35) and SLEN1 (10q22.3) replication in systemic lupus erythematosus stratified by nephritis

scientific article published on August 2004

Sa.54. Positional Identification of Integrin- αMβ2 (ITGAM) as a Susceptibility Gene for Systematic Lupus Erythematosus (SLE)

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Select human anthrax protective antigen epitope-specific antibodies provide protection from lethal toxin challenge

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Sequential autoantigenic determinants of the small nuclear ribonucleoprotein Sm D shared by human lupus autoantibodies and MRL lpr/lpr antibodies

scientific article published on December 1994

Serologic studies of monozygotic twins with systemic lupus erythematosus

scientific article published on April 1, 1992

Sex chromosome aneuploidies among men with systemic lupus erythematosus

scientific article published on 6 December 2011

Sex-specific association of X-linked Toll-like receptor 7 (TLR7) with male systemic lupus erythematosus

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Shared early autoantibody recognition events in the development of anti-Sm B/B' in human lupus

scientific article published on November 1999

Side-chain specificities and molecular modelling of peptide determinants for two anti-Sm B/B' autoantibodies

scientific article published on February 1999

Sjögren's syndrome

scientific article published on 01 January 1991

Smoking is not associated with autoantibody production in systemic lupus erythematosus patients, unaffected first-degree relatives, nor healthy controls

scientific article published on 21 January 2014

Stratification of pedigrees multiplex for systemic lupus erythematosus and for self-reported rheumatoid arthritis detects a systemic lupus erythematosus susceptibility gene (SLER1) at 5p15.3

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Strong viral associations with SLE among Filipinos

scientific article published on 28 July 2017

Suboptimal Clinical Documentation in Young Children with Severe Obesity at Tertiary Care Centers

scientific article published on 06 September 2016

Subphenotype mapping in systemic lupus erythematosus identifies multiple novel loci associated with circulating interferon alpha

scientific article published on 18 September 2014

Systemic lupus erythematosus in adults is associated with previous Epstein-Barr virus exposure

scientific article published in May 2001

Systemic lupus erythematosus: RNA-protein autoantigens, models of disease heterogeneity, and theories of etiology ⬇️

scientific article published on November 1, 1991

Systemic lupus erythematosus: considerations for a genetic approach

scientific article published on 01 November 1994

T-bet+CD11c+ B cells are critical for antichromatin immunoglobulin G production in the development of lupus

scientific article published on 5 October 2017

The Electronic Medical Records and Genomics (eMERGE) Network: past, present, and future ⬇️

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The IRF5-TNPO3 association with systemic lupus erythematosus has two components that other autoimmune disorders variably share

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The PTPN22 C1858T functional polymorphism and autoimmune diseases--a meta-analysis

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The Ro ribonucleoprotein particle: induction of autoantibodies and the detection of Ro RNAs among species

scientific article published in September 1989

The Ro/SSA autoantigen as an immunogen. Some anti-Ro/SSA antibody binds IgG.

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The curiously suspicious: a role for Epstein-Barr virus in lupus

scientific article published on January 2006

The effect of inversion at 8p23 on BLK association with lupus in Caucasian population

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The effects of previous hysterectomy on lupus

scientific article published on October 2009

The genetics of human systemic lupus erythematosus

scientific article published on 01 December 1998

The genetics of primary Sjögren’s syndrome ⬇️

scientific article published on August 1, 2003

The genetics of systemic lupus erythematosus and implications for targeted therapy ⬇️

scientific article published on March 1, 2011

The genetics of systemic lupus erythematosus stratified by renal disease: linkage at 10q22.3 (SLEN1), 2q34-35 (SLEN2), and 11p15.6 (SLEN3).

scientific article published in October 2002

The genetics of systemic lupus erythematosus: putting the pieces together

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The lupus family registry and repository

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The mannose-binding lectin gene polymorphisms and systemic lupus erythematosus: two case-control studies and a meta-analysis

scientific article published in December 2005

The neonatal lupus erythematosus syndrome

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The neonatal lupus syndrome associated with U1RNP (nRNP) antibodies

scientific article published on 01 April 1987

The prevalence, onset, and clinical significance of antiphospholipid antibodies prior to diagnosis of systemic lupus erythematosus

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The recognition of human 60-kDa Ro ribonucleoprotein particles by antibodies associated with cutaneous lupus and neonatal lupus

scientific article published on 01 August 1996

The relationship between anti-Ro (SS-A) antibody-positive Sjögren's syndrome and anti-Ro (SS-A) antibody-positive lupus erythematosus

scientific article published on 01 January 1988

The role of Epstein-Barr virus in systemic lupus erythematosus

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The role of genetic variation near interferon-kappa in systemic lupus erythematosus

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The struggle to find reliable results in exome sequencing data: filtering out Mendelian errors

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The ultrastructural localization of 60-kDa Ro protein and human cytoplasmic RNAs: association with novel electron-dense bodies

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Thrombocytopenia identifies a severe familial phenotype of systemic lupus erythematosus and reveals genetic linkages at 1q22 and 11p13.

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Trans-Ethnic Mapping of Identifies Two Independent SLE-Risk Linkage Groups Enriched for Co-Transcriptional Splicing Marks

scholarly article by Manuel Martínez-Bueno published in August 2018

Trans-ancestral studies fine map the SLE-susceptibility locus TNFSF4.

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Transancestral mapping and genetic load in systemic lupus erythematosus

scientific article published on 17 July 2017

Two Ro (SS-A) autoantibody responses in systemic lupus erythematosus. Correlation of HLA-DR/DQ specificities with quantitative expression of Ro (SS-A) autoantibody

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Two functional lupus-associated BLK promoter variants control cell-type- and developmental-stage-specific transcription

scientific article published on April 2014

Unique clinical characteristics, autoantibodies and medication use in Native American patients with systemic lupus erythematosus

scientific article published on 27 February 2018

Unraveling multiple MHC gene associations with systemic lupus erythematosus: model choice indicates a role for HLA alleles and non-HLA genes in Europeans

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Unraveling the genetics of systemic lupus erythematosus

scientific article published on 22 September 2006

Use of SLICC criteria in a large, diverse lupus registry enables SLE classification of a subset of ACR-designated subjects with incomplete lupus

scientific article published on 17 March 2017

Variable association of reactive intermediate genes with systemic lupus erythematosus in populations with different African ancestry

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Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren's syndrome

scientific article published on 6 October 2013

Variants within MECP2, a key transcription regulator, are associated with increased susceptibility to lupus and differential gene expression in patients with systemic lupus erythematosus

scientific article published on April 2009

Variation in the ICAM1-ICAM4-ICAM5 locus is associated with systemic lupus erythematosus susceptibility in multiple ancestries

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Vitamin D deficiency is associated with an increased autoimmune response in healthy individuals and in patients with systemic lupus erythematosus

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Whole-exome sequencing reveals overlap between macrophage activation syndrome in systemic juvenile idiopathic arthritis and familial hemophagocytic lymphohistiocytosis

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Whole-exome sequencing uncovers oxidoreductases DHTKD1 and OGDHL as linkers between mitochondrial dysfunction and eosinophilic esophagitis

scientific article published on 19 April 2018

X Chromosome Dose and Sex Bias in Autoimmune Diseases: Increased Prevalence of 47,XXX in Systemic Lupus Erythematosus and Sjögren's Syndrome

scientific article published on 29 December 2015

Y3 is the most conserved small RNA component of Ro ribonucleoprotein complexes in vertebrate species

scientific article published on 01 March 1995

ePhenotyping for Abdominal Aortic Aneurysm in the Electronic Medical Records and Genomics (eMERGE) Network: Algorithm Development and Konstanz Information Miner Workflow

scientific article published on 30 July 2015

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