List of works - Yukinori Okada

A Mendelian randomization study identified obesity as a causal risk factor of uterine endometrial cancer in Japanese

scientific article published on 27 September 2020

A catalog of genetic loci associated with kidney function from analyses of a million individuals

scientific article published on 31 May 2019

Amino acid signatures of HLA Class-I and II molecules are strongly associated with SLE susceptibility and autoantibody production in Eastern Asians

article

Association of the RPA3-UMAD1 locus with interstitial lung diseases complicated with rheumatoid arthritis in Japanese

scientific article published on 31 July 2020

Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use

scientific article published on 14 January 2019

Associations of autozygosity with a broad range of human phenotypes

scientific article published on 31 October 2019

Author Correction: Characterizing rare and low-frequency height-associated variants in the Japanese population

scientific article published on 09 March 2020

Biological characterization of expression quantitative trait loci (eQTLs) showing tissue-specific opposite directional effects

scientific article published on 11 July 2019

Cerebral small vessel disease genomics and its implications across the lifespan

scientific article published on 08 December 2020

Characterizing rare and low-frequency height-associated variants in the Japanese population

scientific article published on 27 September 2019

Clinical use of current polygenic risk scores may exacerbate health disparities

scientific article published on 29 March 2019

Confirmation of five novel susceptibility loci for systemic lupus erythematosus (SLE) and integrated network analysis of 82 SLE susceptibility loci

scientific article published on 20 January 2017

Deep whole-genome sequencing reveals recent selection signatures linked to evolution and disease risk of Japanese.

scientific article published on 24 April 2018

Determining the immune environment of cutaneous T-cell lymphoma lesions through the assessment of lesional blood drops

scientific article published on 04 October 2021

Dimensionality reduction reveals fine-scale structure in the Japanese population with consequences for polygenic risk prediction

scientific article published on 26 March 2020

Empirical evaluation of variant calling accuracy using ultra-deep whole-genome sequencing data

scientific article published in Scientific Reports

Functional variants in ADH1B and ALDH2 are non-additively associated with all-cause mortality in Japanese population

scientific article published on 26 September 2019

GWAS of 165,084 Japanese individuals identified nine loci associated with dietary habits

scientific article published on 20 January 2020

GWAS of five gynecologic diseases and cross-trait analysis in Japanese

scientific article published on 05 September 2019

GWAS of smoking behaviour in 165,436 Japanese people reveals seven new loci and shared genetic architecture

scientific article published on 25 March 2019

Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases

scientific article

Genetic and phenotypic landscape of the major histocompatibilty complex region in the Japanese population

scientific article published on 28 January 2019

Genetic and phenotypic landscape of the mitochondrial genome in the Japanese population

scientific article published on 05 March 2020

Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation

scientific article published in Nature Communications

Genome-wide analysis of dental caries and periodontitis combining clinical and self-reported data.

scientific article published on 24 June 2019

Genome-wide association meta-analysis identifies GP2 gene risk variants for pancreatic cancer

scientific article published on 24 June 2020

Genome-wide association study revealed novel loci which aggravate asymptomatic hyperuricaemia into gout

scientific article published on 8 July 2019

Genome-wide meta-analysis identifies multiple novel loci associated with serum uric acid levels in Japanese individuals

scientific article published on 08 April 2019

High-density genotyping of immune-related loci identifies new SLE risk variants in individuals with Asian ancestry

scientific article

Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population

scientific article published on 04 February 2019

Identification of type 2 diabetes loci in 433,540 East Asian individuals

scientific article published on 06 May 2020

LC3 lipidation is essential for TFEB activation during the lysosomal damage response to kidney injury

scientific article published on 28 September 2020

Lysophosphatidylserines derived from microbiota in Crohn's disease elicit pathological Th1 response

scientific article published on 24 May 2022

Meta-analysis of 208370 East Asians identifies 113 susceptibility loci for systemic lupus erythematosus

scientific article published on 03 December 2020

Metagenome-wide association study of gut microbiome revealed novel aetiology of rheumatoid arthritis in the Japanese population

scientific article published on 07 November 2019

OMARU: a robust and multifaceted pipeline for metagenome-wide association study

scientific article published on 07 March 2022

Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

scientific article published on 01 July 2019

Response to: 'Can sexual dimorphism in rheumatoid arthritis be attributed to the different abundance of Gardnerella?' by Liu et al

scientific article published on 25 March 2020

Subtype-specific gout susceptibility loci and enrichment of selection pressure on ABCG2 and ALDH2 identified by subtype genome-wide meta-analyses of clinically defined gout patients

scientific article published on 1 April 2020

Suppression of autophagic activity by Rubicon is a signature of aging

scientific article published on 19 February 2019

Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels

scientific article published on 02 October 2019

The positive correlation between Porphyromonas gingivalis and Prevotella spp. Response to: 'Comment on 'Metagenome-wide association study of gut microbiome revealed novel aetiology of rheumatoid arthritis in the Japanese population' by Kishikawa et

scientific article published on 29 May 2020

The power of genetic diversity in genome-wide association studies of lipids

Trans-biobank analysis with 676,000 individuals elucidates the association of polygenic risk scores of complex traits with human lifespan

scientific article published on 23 March 2020

Two decades after Human Genome Project: do large-genetic studies lead to path of the genomic medicine of complex diseases?

scientific article published on 11 December 2020

Whole gut virome analysis of 476 Japanese revealed a link between phage and autoimmune disease

scientific article published on 08 December 2021

eLD: entropy-based linkage disequilibrium index between multiallelic sites

scientific article published on 22 October 2018

List of works by Yukinori Okada