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List of works by Kenneth Marek

123I-FP-CIT SPECT [(123) I-2β-carbomethoxy-3β-(4-iodophenyl)-N-(3-fluoropropyl) nortropane single photon emission computed tomography] Imaging in a p.A53T α-synuclein Parkinson's disease cohort versus Parkinson's disease

scientific article published on 04 October 2018

A Bayesian mathematical model of motor and cognitive outcomes in Parkinson's disease

scientific article

A longitudinal program for biomarker development in Parkinson's disease: a feasibility study

scientific article published in October 2009

A practical approach to remote longitudinal follow-up of Parkinson's disease: the FOUND study

scientific article published on 11 February 2014

A randomized, controlled trial of remacemide for motor fluctuations in Parkinson's disease

scientific article

Abolishing the 1-year rule: How much evidence will be enough?

scientific article published on 26 September 2016

Association of cerebrospinal fluid β-amyloid 1-42, T-tau, P-tau181, and α-synuclein levels with clinical features of drug-naive patients with early Parkinson disease

scientific article

Author Response

Baseline prevalence and longitudinal evolution of non-motor symptoms in early Parkinson's disease: the PPMI cohort

scientific article published on 6 October 2017

Biomarkers for Parkinson's [corrected] disease: tools to assess Parkinson's disease onset and progression

scientific article published on 01 December 2008

CSF biomarkers associated with disease heterogeneity in early Parkinson's disease: the Parkinson's Progression Markers Initiative study

scientific article published on 28 March 2016

Can we image premotor Parkinson disease?

scientific article published on February 2009

Candidate inflammatory biomarkers display unique relationships with alpha-synuclein and correlate with measures of disease severity in subjects with Parkinson's disease

scientific article published on 18 August 2017

Change in PDE10 across early Huntington disease assessed by [18F]MNI-659 and PET imaging

scientific article

Clinical and Dopamine Transporter Imaging Characteristics of Leucine- Rich Repeat Kinase 2 (LRRK2) and Glucosylceramidase Beta (GBA) Parkinson's Disease Participants in the Parkinson's Progression Markers Initiative: A Cross-Sectional Study

scientific article published on 19 February 2020

Clinical and Imaging Progression in the PARS Cohort: Long-Term Follow-up

scientific article published on 13 July 2020

Clinical and dopamine transporter imaging characteristics of non-manifest LRRK2 and GBA mutation carriers in the Parkinson's Progression Markers Initiative (PPMI): a cross-sectional study

scientific article published on 31 October 2019

Clinical correlates of raphe serotonergic dysfunction in early Parkinson's disease.

scientific article published on 23 July 2015

Clinical utility of DaTscan™ imaging in the evaluation of patients with parkinsonism: a US perspective

scientific article published on 4 November 2016

Cognition and the course of prodromal Parkinson's disease.

scientific article published on 24 October 2017

Cognition in individuals at risk for Parkinson's: Parkinson associated risk syndrome (PARS) study findings

scientific article published on 21 August 2015

Comparison of an Online-Only Parkinson's Disease Research Cohort to Cohorts Assessed In Person

scientific article published on 01 January 2020

Concordance for Parkinson's disease in twins: A 20-year update

scientific article published on 11 March 2019

Conversion to Parkinson Disease in the PARS Hyposmic and Dopamine Transporter-Deficit Prodromal Cohort

scientific article published on 8 June 2017

Decreased single-photon emission computed tomographic [123I]beta-CIT striatal uptake correlates with symptom severity in Parkinson's disease

scientific article published in October 1995

Development and In Vivo Preclinical Imaging of Fluorine-18-Labeled Synaptic Vesicle Protein 2A (SV2A) PET Tracers

scientific article published on 01 June 2019

Development of a Disease Progression Model for Leucine-Rich Repeat Kinase 2 in Parkinson's Disease to Inform Clinical Trial Designs

scientific article published on 05 December 2019

Diffusion imaging of nigral alterations in early Parkinson's disease with dopaminergic deficits

scientific article

Displacement of serotonin and dopamine transporters by venlafaxine extended release capsule at steady state: a [123I]2beta-carbomethoxy-3beta-(4-iodophenyl)-tropane single photon emission computed tomography imaging study

scientific article

Do dopamine agonists or levodopa modify Parkinson's disease progression?

scientific article

Dopamine Transporter Neuroimaging as an Enrichment Biomarker in Early Parkinson's Disease Clinical Trials: A Disease Progression Modeling Analysis.

scientific article

Dopamine agonists and Parkinson's disease progression: what can we learn from neuroimaging studies

scientific article

Dopamine transporter imaging is associated with long-term outcomes in Parkinson's disease

scientific article

Dopamine transporter imaging predicts clinically-defined α-synucleinopathy in REM sleep behavior disorder

scientific article published on 15 December 2020

Double-blind, randomized, controlled trial of rasagiline as monotherapy in early Parkinson's disease patients

scientific article

Early Clinical Predictors of Treatment-Resistant and Functional Outcomes in Parkinson's Disease

scientific article published on 14 December 2015

Effect of treatment with L-dopa/carbidopa or L-selegiline on striatal dopamine transporter SPECT imaging with [123I]beta-CIT.

scientific article

Estimating the half-lives of PCB congeners in former capacitor workers measured over a 28-year interval

scientific article published on 10 March 2010

Evaluation of dosimetry, quantitative methods and test-retest variability of 18F-PI-2620 PET for the assessment of tau deposits in the human brain

scientific article published on 11 November 2019

Evolution of Alzheimer's Disease Cerebrospinal Fluid Biomarkers in Early Parkinson's Disease

scientific article published on 16 June 2020

FMR1 gene expansion and scans without evidence of dopaminergic deficits in parkinsonism patients

scientific article

Fatigue in levodopa-naive subjects with Parkinson disease

scientific article

Finding useful biomarkers for Parkinson's disease

article

Imaging prodromal Parkinson disease: the Parkinson Associated Risk Syndrome Study

scientific article

Imaging the dopamine system to assess disease-modifying drugs: studies comparing dopamine agonists and levodopa

scientific article published on September 2003

Impaired olfaction and other prodromal features in the Parkinson At-Risk Syndrome Study.

scientific article published on 11 January 2012

Individual-reader diagnostic performance and between-reader agreement in assessment of subjects with Parkinsonian syndrome or dementia using 123I-ioflupane injection (DaTscan) imaging

scientific article published on 12 June 2014

Innovative Recruitment Strategies to Increase Diversity of Participation in Parkinson's Disease Research: The Fox Insight Cohort Experience

scientific article published on 01 January 2020

Kinetic modeling, test-retest, and dosimetry of 123I-MNI-420 in humans

scientific article published on 22 August 2013

Levodopa and the progression of Parkinson's disease

scientific article

Longitudinal CSF biomarkers in patients with early Parkinson disease and healthy controls.

scientific article published on 13 October 2017

Longitudinal analyses of cerebrospinal fluid α-Synuclein in prodromal and early Parkinson's disease

scientific article published on 30 July 2019

Longitudinal change of clinical and biological measures in early Parkinson's disease: Parkinson's progression markers initiative cohort

scientific article published on 23 March 2018

Longitudinal follow-up of SWEDD subjects in the PRECEPT Study

scientific article

Looking Backward to Move Forward: Early Detection of Neurodegenerative Disorders ⬇️

scientific article published on October 31, 2003

MDS clinical diagnostic criteria for Parkinson's disease

scientific article

MDS research criteria for prodromal Parkinson's disease

scientific article

Molecular Neuroimaging of the Dopamine Transporter as a Patient Enrichment Biomarker for Clinical Trials for Early Parkinson's Disease

scholarly article by Klaus Romero et al published May 2019 in Clinical and Translational Science

Molecular PET imaging in multicenter Alzheimer's therapeutic trials: current trends and implementation strategies

scientific article published on December 2011

Movement disorder society criteria for clinically established early Parkinson's disease

scholarly article by Daniela Berg et al published 25 August 2018 in Movement Disorders

Neuroimaging over the course of Parkinson's disease: from early detection of the at-risk patient to improving pharmacotherapy of later-stage disease

scientific article

Novel recruitment strategy to enrich for LRRK2 mutation carriers

scientific article

Observations on a 2-Step Approach to Screening for Parkinson Disease-Reply

scientific article published on 6 November 2017

Occupational exposure to PCBs reduces striatal dopamine transporter densities only in women: a beta-CIT imaging study

scientific article

Optimized, automated striatal uptake analysis applied to SPECT brain scans of Parkinson's disease patients

scientific article

Plasma α-synuclein and cognitive impairment in the Parkinson's Associated Risk Syndrome: A pilot study

scientific article published on 27 April 2018

Portable objective assessment of upper extremity motor function in Parkinson's disease

scientific article published on 19 July 2017

Pramipexole in patients with early Parkinson's disease (PROUD): a randomised delayed-start trial

scientific article published on 31 May 2013

Pramipexole vs levodopa as initial treatment for Parkinson disease: a 4-year randomized controlled trial

scientific article

Preclinical properties and human in vivo assessment of 123I-ABC577 as a novel SPECT agent for imaging amyloid-β.

scientific article published on 21 October 2015

Predicting Progression in Parkinson's Disease Using Baseline and 1-Year Change Measures

scientific article published on 01 January 2019

Predictors of time to initiation of symptomatic therapy in early Parkinson's disease

scientific article published on 17 May 2016

Rationale for delayed-start study of pramipexole in Parkinson's disease: the PROUD study

scientific article published in August 2010

Reply: Unusual DAT scan results

scientific article published on 4 April 2013

Risk factors for Parkinson's disease and impaired olfaction in relatives of patients with Parkinson's disease

scientific article published on 01 November 2007

Role of DAT-SPECT in the diagnostic work up of parkinsonism

scientific article published on July 2007

Serotonergic dysfunction in depression associated with Parkinson's disease

scientific article published on September 1, 1992

Serum urate and probability of dopaminergic deficit in early "Parkinson's disease".

scientific article

Serum urate as a predictor of clinical and radiographic progression in Parkinson disease

scientific article

Single-photon emission tomography and dopamine transporter imaging in Parkinson's disease

scientific article

Striatal dopamine transporters correlate with simple reaction time in elderly subjects

scientific article

Supplement neuroimaging movement disorders

scientific article published in January 2009

T156. IN VIVO CHARACTERIZATION OF THE FIRST AGONIST DOPAMINE D1 RECEPTORS PET IMAGING TRACER [18F]MNI-968 IN HUMAN.

scientific article

Tau PET imaging with 18F-PI-2620 in patients with Alzheimer's disease and healthy controls: a first-in-human study

scientific article published on 11 November 2019

Tauopathy PET and amyloid PET in the diagnosis of chronic traumatic encephalopathies: studies of a retired NFL player and of a man with FTD and a severe head injury.

scientific article

TechSight. Imaging. A molecular map for neurodegeneration

scientific article

The Effect of the COVID-19 Pandemic on People with Parkinson's Disease

scientific article published on 10 September 2020

The Parkinson's progression markers initiative (PPMI) - establishing a PD biomarker cohort

scientific article published on 31 October 2018

The Qualification of an Enrichment Biomarker for Clinical Trials Targeting Early Stages of Parkinson's Disease

article published in 2019

The molecular basis of dopaminergic brain imaging in Parkinson's disease

scientific article published on February 1, 2012

The natural history of the syndrome of primary progressive freezing gait

scientific article

The new definition and diagnostic criteria of Parkinson's disease

scientific article published on 11 April 2016

The phosphodiesterase 10 positron emission tomography tracer, [18F]MNI-659, as a novel biomarker for early Huntington disease

scientific article published in December 2014

The prodromal phase of leucine-rich repeat kinase 2-associated Parkinson disease: Clinical and imaging Studies

scientific article

The role of neuroimaging in the early diagnosis and evaluation of Parkinson's disease.

scientific article

The role of radiotracer imaging in Parkinson disease

scientific article

The role of the core imaging laboratory in multicenter trials

scientific article published in September 2010

The specificity and sensitivity of transcranial ultrasound in the differential diagnosis of Parkinson's disease: a prospective blinded study

scientific article published on 3 April 2008

Time to redefine PD? Introductory statement of the MDS Task Force on the definition of Parkinson's disease

scientific article

Traditional neuropsychological correlates and reliability of the automated neuropsychological assessment metrics-4 battery for Parkinson's disease

scientific article

Unique roles of SPET brain imaging in clinical and research studies. Lessons from Parkinson's disease research

scientific article

Use of white matter reference regions for detection of change in florbetapir positron emission tomography from completed phase 3 solanezumab trials

scientific article

Validation of Serum Neurofilament Light Chain as a Biomarker of Parkinson's Disease Progression

scientific article published on 15 August 2020

[(123)I]beta-CIT SPECT imaging demonstrates reduced density of striatal dopamine transporters in Parkinson's disease and multiple system atrophy

scientific article published in November 2001

[123I] beta-CIT/SPECT imaging demonstrates bilateral loss of dopamine transporters in hemi-Parkinson's disease

scientific article published in January 1996

[123I]beta-CIT SPECT imaging assessment of the rate of Parkinson's disease progression

scientific article published in December 2001

[18F]GTP1 (Genentech Tau Probe 1), a radioligand for detecting neurofibrillary tangle tau pathology in Alzheimer's disease

scientific article published on 28 June 2019

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