List of works - Thomas Uwe Schwartz

3D ultrastructure of the nuclear pore complex ⬇️

scientific article published on January 11, 2012

A general amphipathic alpha-helical motif for sensing membrane curvature.

scientific article

A nanobody suite for yeast scaffold nucleoporins provides details of the nuclear pore complex structure

scientific article published on 02 December 2020

Allosteric activation of apicomplexan calcium-dependent protein kinases.

scientific article published on 24 August 2015

Alternate rRNA secondary structures as regulators of translation

scientific article

Architectural nucleoporins Nup157/170 and Nup133 are structurally related and descend from a second ancestral element.

scientific article

Atomic structure of the Y complex of the nuclear pore.

scientific article published on 30 March 2015

Correction: Exponential Megapriming PCR (EMP) Cloning—Seamless DNA Insertion into Any Target Plasmid without Sequence Constraints.

scientific article published on 20 September 2013

Crystal structure of nucleoporin Nic96 reveals a novel, intricate helical domain architecture

scientific article

Crystal structure of the Zalpha domain of the human editing enzyme ADAR1 bound to left-handed Z-DNA

scientific article

Crystallization and preliminary studies of the DNA-binding domain Za from ADAR1 complexed to left-handed DNA

scientific article published on 01 July 1999

Crystallographic and Biochemical Analysis of the Ran-binding Zinc Finger Domain

scientific article

Exponential megapriming PCR (EMP) cloning--seamless DNA insertion into any target plasmid without sequence constraints.

scientific article

Finding the missing link

scientific article

Homodimerization of the G protein SRbeta in the nucleotide-free state involves proline cis/trans isomerization in the switch II region.

scientific article

How lamina-associated polypeptide 1 (LAP1) activates Torsin.

scientific article

LINC Complexes Form by Binding of Three KASH Peptides to Domain Interfaces of Trimeric SUN Proteins ⬇️

scientific article published on May 25, 2012

LINC complexes promote homologous recombination in part through inhibition of nonhomologous end joining

scientific article published on 12 December 2016

Membrane-coating lattice scaffolds in the nuclear pore and vesicle coats: commonalities, differences, challenges.

scientific article

Modularity within the architecture of the nuclear pore complex.

scientific article

Molecular architecture of the Nup84–Nup145C–Sec13 edge element in the nuclear pore complex lattice

scientific article

Molecular basis for Nup37 and ELY5/ELYS recruitment to the nuclear pore complex

scientific article

Optimized E. coli expression strain LOBSTR eliminates common contaminants from His-tag purification

scientific article

Origins and evolution of cotranslational transport to the ER.

scientific article published on January 2007

Proteolytic dissection of Zab, the Z-DNA-binding domain of human ADAR1.

scientific article published on January 1999

Purification, crystallization and preliminary X-ray analysis of a Nup107-Nup133 heterodimeric nucleoporin complex

scientific article

Quantifying the heterogeneity of macromolecular machines by mass photometry

scientific article published on 14 April 2020

Regulated Formation of an Amyloid-like Translational Repressor Governs Gametogenesis

scientific article

Scaffold nucleoporins Nup188 and Nup192 share structural and functional properties with nuclear transport receptors

scientific article

Spectroscopic Characterization of a DNA-Binding Domain, Zα, from the Editing Enzyme, dsRNA Adenosine Deaminase: Evidence for Left-Handed Z-DNA in the Zα−DNA Complex ⬇️

scientific article published on September 22, 1998

Structural Characterization of Bardet-Biedl Syndrome 9 Protein (BBS9).

scientific article published on 17 June 2015

Structural and Functional Studies of Nup107/Nup133 Interaction and Its Implications for the Architecture of the Nuclear Pore Complex

scientific article

Structural and Functional Studies of the 252 kDa Nucleoporin ELYS Reveal Distinct Roles for Its Three Tethered Domains

scientific article

Structural basis for leucine sensing by the Sestrin2-mTORC1 pathway

scientific article

Structural basis for the function of the beta subunit of the eukaryotic signal recognition particle receptor

scientific article (publication date: 21 March 2003)

Structural insights into LINC complexes ⬇️

scientific article published on April 15, 2013

Structure of the DLM-1-Z-DNA complex reveals a conserved family of Z-DNA-binding proteins

scientific article

Structures of TorsinA and its disease-mutant complexed with an activator reveal the molecular basis for primary dystonia.

scientific article published on 04 August 2016

The AAA + ATPase TorsinA polymerizes into hollow helical tubes with 8.5 subunits per turn

scientific article published on 22 July 2019

The Antiviral Mechanism of an Influenza A Virus Nucleoprotein-Specific Single-Domain Antibody Fragment

scientific article published on 13 December 2016

The Caenorhabditis elegans Protein FIC-1 Is an AMPylase That Covalently Modifies Heat-Shock 70 Family Proteins, Translation Elongation Factors and Histones

scientific article

The Structure of the Scaffold Nucleoporin Nup120 Reveals a New and Unexpected Domain Architecture

scientific article

The Zalpha domain from human ADAR1 binds to the Z-DNA conformer of many different sequences

scientific article

The interaction between Z-DNA and the Zab domain of double-stranded RNA adenosine deaminase characterized using fusion nucleases.

scientific article

The nuclear pore complex has entered the atomic age.

scientific article published on September 2009

The nuclear pore complex--structure and function at a glance.

scientific article

The stoichiometry of the nucleoporin 62 subcomplex of the nuclear pore in solution.

scientific article

The transition between the B and Z conformations of DNA investigated by targeted molecular dynamics simulations with explicit solvation.

scientific article published in October 2006

The zab domain of the human RNA editing enzyme ADAR1 recognizes Z-DNA when surrounded by B-DNA

scientific article (publication date: September 2000)

Yeast Nup84-Nup133 complex structure details flexibility and reveals conservation of the membrane anchoring ALPS motif

scientific article published on 27 November 2020

List of works by Thomas Uwe Schwartz

3D ultrastructure of the nuclear pore complex ⬇️

A general amphipathic alpha-helical motif for sensing membrane curvature.

A nanobody suite for yeast scaffold nucleoporins provides details of the nuclear pore complex structure

Allosteric activation of apicomplexan calcium-dependent protein kinases.

Alternate rRNA secondary structures as regulators of translation

Architectural nucleoporins Nup157/170 and Nup133 are structurally related and descend from a second ancestral element.

Atomic structure of the Y complex of the nuclear pore.

Correction: Exponential Megapriming PCR (EMP) Cloning—Seamless DNA Insertion into Any Target Plasmid without Sequence Constraints.

Crystal structure of nucleoporin Nic96 reveals a novel, intricate helical domain architecture

Crystal structure of the Zalpha domain of the human editing enzyme ADAR1 bound to left-handed Z-DNA

Crystallization and preliminary studies of the DNA-binding domain Za from ADAR1 complexed to left-handed DNA

Crystallographic and Biochemical Analysis of the Ran-binding Zinc Finger Domain

Exponential megapriming PCR (EMP) cloning--seamless DNA insertion into any target plasmid without sequence constraints.

Finding the missing link

Homodimerization of the G protein SRbeta in the nucleotide-free state involves proline cis/trans isomerization in the switch II region.

How lamina-associated polypeptide 1 (LAP1) activates Torsin.

LINC Complexes Form by Binding of Three KASH Peptides to Domain Interfaces of Trimeric SUN Proteins ⬇️

LINC complexes promote homologous recombination in part through inhibition of nonhomologous end joining

Membrane-coating lattice scaffolds in the nuclear pore and vesicle coats: commonalities, differences, challenges.

Modularity within the architecture of the nuclear pore complex.

Molecular architecture of the Nup84–Nup145C–Sec13 edge element in the nuclear pore complex lattice

Molecular basis for Nup37 and ELY5/ELYS recruitment to the nuclear pore complex

Optimized E. coli expression strain LOBSTR eliminates common contaminants from His-tag purification

Origins and evolution of cotranslational transport to the ER.

Proteolytic dissection of Zab, the Z-DNA-binding domain of human ADAR1.

Purification, crystallization and preliminary X-ray analysis of a Nup107-Nup133 heterodimeric nucleoporin complex

Quantifying the heterogeneity of macromolecular machines by mass photometry

Regulated Formation of an Amyloid-like Translational Repressor Governs Gametogenesis

Scaffold nucleoporins Nup188 and Nup192 share structural and functional properties with nuclear transport receptors

Spectroscopic Characterization of a DNA-Binding Domain, Zα, from the Editing Enzyme, dsRNA Adenosine Deaminase: Evidence for Left-Handed Z-DNA in the Zα−DNA Complex ⬇️

Structural Characterization of Bardet-Biedl Syndrome 9 Protein (BBS9).

Structural and Functional Studies of Nup107/Nup133 Interaction and Its Implications for the Architecture of the Nuclear Pore Complex

Structural and Functional Studies of the 252 kDa Nucleoporin ELYS Reveal Distinct Roles for Its Three Tethered Domains

Structural basis for leucine sensing by the Sestrin2-mTORC1 pathway

Structural basis for the function of the beta subunit of the eukaryotic signal recognition particle receptor

Structural insights into LINC complexes ⬇️

Structure of the DLM-1-Z-DNA complex reveals a conserved family of Z-DNA-binding proteins

Structures of TorsinA and its disease-mutant complexed with an activator reveal the molecular basis for primary dystonia.

The AAA + ATPase TorsinA polymerizes into hollow helical tubes with 8.5 subunits per turn

The Antiviral Mechanism of an Influenza A Virus Nucleoprotein-Specific Single-Domain Antibody Fragment

The Caenorhabditis elegans Protein FIC-1 Is an AMPylase That Covalently Modifies Heat-Shock 70 Family Proteins, Translation Elongation Factors and Histones

The Structure of the Scaffold Nucleoporin Nup120 Reveals a New and Unexpected Domain Architecture

The Zalpha domain from human ADAR1 binds to the Z-DNA conformer of many different sequences

The interaction between Z-DNA and the Zab domain of double-stranded RNA adenosine deaminase characterized using fusion nucleases.

The nuclear pore complex has entered the atomic age.

The nuclear pore complex--structure and function at a glance.

The stoichiometry of the nucleoporin 62 subcomplex of the nuclear pore in solution.

The transition between the B and Z conformations of DNA investigated by targeted molecular dynamics simulations with explicit solvation.

The zab domain of the human RNA editing enzyme ADAR1 recognizes Z-DNA when surrounded by B-DNA

Yeast Nup84-Nup133 complex structure details flexibility and reveals conservation of the membrane anchoring ALPS motif