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List of works by J Christopher Fromme

A Steric Gating Mechanism Dictates the Substrate Specificity of a Rab-GEF

scientific article published on 06 December 2018

A rapid and quantitative coat protein complex II vesicle formation assay using luciferase reporters.

scientific article published on 24 December 2011

Analysis of Arf1 GTPase-Dependent Membrane Binding and Remodeling Using the Exomer Secretory Vesicle Cargo Adaptor

scientific article

Base excision repair.

scientific article

Biochemical methods for studying kinetic regulation of Arf1 activation by Sec7.

scientific article published on 11 June 2015

Capturing endosomal vesicles at the Golgi.

scientific article published in November 2017

Cargo adaptors: structures illuminate mechanisms regulating vesicle biogenesis.

scientific article

Correction: The Sec7 N-terminal regulatory domains facilitate membrane-proximal activation of the Arf1 GTPase.

scientific article published on 9 June 2016

DNA glycosylase recognition and catalysis

scientific article

DNA lesion recognition by the bacterial repair enzyme MutM

scientific article

Data publication with the structural biology data grid supports live analysis

scientific article

Distinct N-terminal regions of the exomer secretory vesicle cargo Chs3 regulate its trafficking itinerary.

scientific article

Four GTPases differentially regulate the Sec7 Arf-GEF to direct traffic at the trans-golgi network.

scientific article published on 11 September 2014

GTPase cross talk regulates TRAPPII activation of Rab11 homologues during vesicle biogenesis

scientific article

Membrane trafficking: licensing a cargo receptor for ER export

scientific article published on 01 January 2015

NMT1 and NMT2 are lysine myristoyltransferases regulating the ARF6 GTPase cycle

scientific article published on 26 February 2020

Regulation of Arf activation occurs via distinct mechanisms at early and late Golgi compartments

scientific article published on 4 October 2017

Regulation of vesicle trafficking: GTPases and friends.

scientific article

Structural and mechanistic studies on repair of 8-oxoguanine in mammalian cells.

scientific article

Structural basis for activation, assembly and membrane binding of ESCRT-III Snf7 filaments

scientific article

Structural basis for membrane binding and remodeling by the exomer secretory vesicle cargo adaptor.

scientific article published on September 2014

Structural basis for removal of adenine mispaired with 8-oxoguanine by MutY adenine DNA glycosylase

scientific article

Structural basis of TRAPPIII-mediated Rab1 activation

scientific article published on 21 May 2021

Structural insights into lesion recognition and repair by the bacterial 8-oxoguanine DNA glycosylase MutM

scientific article

Structure of human cytidine deaminase bound to a potent inhibitor

scientific article

The HUS-box is required for allosteric regulation of the Sec7 Arf-GEF.

scientific article published on 7 March 2018

The Sec7 Arf-GEF is recruited to the trans-Golgi network by positive feedback.

scientific article published on April 2012

The Sec7 N-terminal regulatory domains facilitate membrane-proximal activation of the Arf1 GTPase

scientific article published on 14 January 2016

The TRAPPIII complex activates the GTPase Ypt1 (Rab1) in the secretory pathway.

scientific article published on 6 November 2017

The exomer cargo adaptor features a flexible hinge domain.

scientific article

The exomer cargo adaptor structure reveals a novel GTPase-binding domain ⬇️

scientific article published on September 21, 2012

The genetic basis of a craniofacial disease provides insight into COPII coat assembly.

scientific article

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