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List of works by Marie-Françoise Chesselet

3,4-dihydroxyphenylalanine reverses the motor deficits in Pitx3-deficient aphakia mice: behavioral characterization of a novel genetic model of Parkinson's disease.

scientific article

A GCase chaperone improves motor function in a mouse model of synucleinopathy

scientific article

A Molecular Tweezer Ameliorates Motor Deficits in Mice Overexpressing α-Synuclein

scientific article published on 05 June 2017

A Progressive Mouse Model of Parkinson's Disease: The Thy1-aSyn (“Line 61”) Mice ⬇️

scientific article published on April 1, 2012

A de novo compound targeting α-synuclein improves deficits in models of Parkinson's disease

scientific article published on 27 September 2016

A pilot trial of the microtubule-interacting peptide (NAP) in mice overexpressing alpha-synuclein shows improvement in motor function and reduction of alpha-synuclein inclusions

scientific article

Abnormal colonic motility in mice overexpressing human wild-type alpha-synuclein

scientific article

Adult reserve stem cells and their potential for tissue engineering

scientific article published on January 2004

Alpha-synuclein and transgenic mouse models

scientific article published in November 2004

Analysis of striatal transcriptome in mice overexpressing human wild-type alpha-synuclein supports synaptic dysfunction and suggests mechanisms of neuroprotection for striatal neurons ⬇️

scientific article published on December 13, 2011

Animal Models of Neurological Disorders ⬇️

scientific article published on April 1, 2012

Animal models of Parkinson's disease progression

scientific article published on 14 February 2008

Animal models of neurological disorders

scientific article published on July 2005

Animal models of the non-motor features of Parkinson's disease ⬇️

scientific article published on January 3, 2012

Apoptosis in Huntington's disease.

scientific article

Bacterial artificial chromosome transgenic mice expressing a truncated mutant parkin exhibit age-dependent hypokinetic motor deficits, dopaminergic neuron degeneration, and accumulation of proteinase K-resistant alpha-synuclein

scientific article

Behavioral and immunohistochemical effects of chronic intravenous and subcutaneous infusions of varying doses of rotenone

scientific article

Behavioral phenotypes and pharmacology in genetic mouse models of Parkinsonism

scientific article published on September 2006

Chronic administration of cholesterol oximes in mice increases transcription of cytoprotective genes and improves transcriptome alterations induced by alpha-synuclein overexpression in nigrostriatal dopaminergic neurons

scientific article

Cognitive deficits in a mouse model of pre‐manifest Parkinson’s disease ⬇️

scientific article published on February 22, 2012

Comparison of huntingtin proteolytic fragments in human lymphoblast cell lines and human brain

scientific article published on July 2002

Context dependent neuroprotective properties of prion protein (PrP).

scientific article

Development and anatomic localization of torsinA

scientific article published on January 1, 2004

Development of striatal fast-spiking GABAergic interneurons

scientific article published on January 2007

Direct regulation of adult brain function by the male-specific factor SRY

scientific article

Early behavioral deficits in R6/2 mice suitable for use in preclinical drug testing

scientific article published in October 2005

Early motor dysfunction and striosomal distribution of huntingtin microaggregates in Huntington's disease knock-in mice

scientific journal article

Effect of GABA(A) receptor stimulation in the subthalamic nucleus on motor deficits induced by nigrostriatal lesions in the rat.

scientific article published in May 2005

Effects of antioxidants on cancer prevention and neuromotor performance in Atm deficient mice

scientific article

Effects of decreased dopamine transporter levels on nigrostriatal neurons and paraquat/maneb toxicity in mice

scientific article published in December 2016

Elevated tonic extracellular dopamine concentration and altered dopamine modulation of synaptic activity precede dopamine loss in the striatum of mice overexpressing human α‐synuclein ⬇️

scientific article published on April 12, 2011

Evidence for behavioral benefits of early dietary supplementation with CoEnzymeQ10 in a slowly progressing mouse model of Huntington's disease ⬇️

scientific article published on October 20, 2011

Functional and molecular development of striatal fast-spiking GABAergic interneurons and their cortical inputs

scientific article published in September 2005

Genetic mouse models of Huntington's and Parkinson's diseases: illuminating but imperfect

scientific article published in November 2004

Genetic mouse models of Parkinson's disease The state of the art.

scientific article published on January 2010

Genetic mouse models of parkinsonism: strengths and limitations

scientific article

Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson's Disease

scientific article

Human Neural Stem Cell Transplantation Rescues Functional Deficits in R6/2 and Q140 Huntington's Disease Mice

scientific article published on 6 December 2017

Impaired Baroreflex Function in Mice Overexpressing Alpha-Synuclein ⬇️

scientific article published on July 23, 2013

In vivo alpha-synuclein overexpression in rodents: a useful model of Parkinson's disease?

scientific article published on 23 August 2007

Intranasal NAP (davunetide) decreases tau hyperphosphorylation and moderately improves behavioral deficits in mice overexpressing α-synuclein

scientific article

Mechanisms of subventricular zone expansion after focal cortical ischemic injury.

scientific article published in July 2005

Metabolic correlates of lesion-specific plasticity: an in vivo imaging study.

scientific article published in March 2004

Migration and fate of newly born cells after focal cortical ischemia in adult rats

scientific article

Mitochondria-Targeted Cholesterol Oximes Increase Dopamine-Related Gene Expression and Behavior in Mice Over-Expressing Alpha-Synuclein, a Model of Pre-Manifest Parkinson’s Disease

article

Mitochondrial dysfunction and oxidative stress in Parkinson's disease ⬇️

scientific article published on April 30, 2013

Modelling of Parkinson's disease in mice ⬇️

scientific article published on December 1, 2011

Mouse Models of Cognitive Deficits Due to Alpha-Synuclein Pathology ⬇️

scientific article published on January 1, 2011

Mouse models of Huntington's disease

scientific article

Neuronal NOS and cyclooxygenase-2 contribute to DNA damage in a mouse model of Parkinson disease

scientific article published on 17 July 2009

Neuronal differentiation of stem cells isolated from adult muscle.

scientific article published in September 2002

Neurons express hemoglobin alpha- and beta-chains in rat and human brains

scientific article

Olfactory deficits in mice overexpressing human wildtype alpha-synuclein

scientific article

Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons

scientific journal article

Region specific mitochondrial impairment in mice with widespread overexpression of alpha-synuclein

scientific article

Region-specific sprouting of crossed corticofugal fibers after unilateral cortical lesions in adult mice

scientific article published in February 2006

Regionally-specific microglial activation in young mice over-expressing human wildtype alpha-synuclein

scientific article published on 27 June 2012

Selective blockade of serotonin 2C receptor enhances Fos expression specifically in the striatum and the subthalamic nucleus within the basal ganglia

scientific article

Serotonin2C ligands exhibiting full negative and positive intrinsic activity elicit purposeless oral movements in rats: distinct effects of agonists and inverse agonists in a rat model of Parkinson's disease

scientific article published on 3 May 2012

Sleep dysfunction and EEG alterations in mice overexpressing alpha-synuclein

scientific article

Social Cognition Impairments in Mice Overexpressing Alpha-Synuclein Under the Thy1 Promoter, a Model of Pre-manifest Parkinson's Disease

scientific article published on 13 January 2015

Strengths and limitations of genetic mouse models of Parkinson's disease

scientific article

Striatal atrophy and dendritic alterations in a knock-in mouse model of Huntington's disease ⬇️

scientific article published on February 4, 2012

Synchronous neuronal activity is a signal for axonal sprouting after cortical lesions in the adult.

scientific article

The biological sciences section program at the 60th Annual Meeting of the Gerontological Society of America

scientific article published in April 2008

The etiopathogenesis of Parkinson disease and suggestions for future research. Part I.

scientific article published on April 2007

The etiopathogenesis of Parkinson disease and suggestions for future research. Part II.

scientific article published on May 2007

Time course of early motor and neuropathological anomalies in a knock-in mouse model of Huntington's disease with 140 CAG repeats

scientific journal article

Transgenic rodent models to study alpha-synuclein pathogenesis, with a focus on cognitive deficits

scientific article published on January 2015

Traumatic brain injury in adult rats causes progressive nigrostriatal dopaminergic cell loss and enhanced vulnerability to the pesticide paraquat

scientific article

Variable effects of chronic subcutaneous administration of rotenone on striatal histology

scientific article published in October 2004

Vocalization deficits in mice over-expressing alpha-synuclein, a model of pre-manifest Parkinson's disease

scientific article

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