List of works by Thomas J Montine

4-Hydroxy-2(E)-nonenal inhibits CNS mitochondrial respiration at multiple sites

scientific article published in April 1999

4-Hydroxy-2-Nonenal Pyrrole Adducts in Human Neurodegenerative Disease ⬇️

scientific article published on August 1, 1997

4-Hydroxy-trans-2-nonenoic acid is a gamma-hydroxybutyrate receptor ligand in the cerebral cortex and hippocampus

scientific article

70-year-old man with enlarged pineal gland

scientific article published in October 2008

A combined dataset of human cerebrospinal fluid proteins identified by multi-dimensional chromatography and tandem mass spectrometry

scientific article published on February 2007

A nonhuman primate model of early Alzheimer's disease pathologic change: Implications for disease pathogenesis.

scientific article published on 19 November 2018

A novel Alzheimer disease locus located near the gene encoding tau protein.

scientific article

A novel progranulin mutation associated with variable clinical presentation and tau, TDP43 and alpha-synuclein pathology

scientific article published on 17 April 2007

A patient with Huntington's disease and long-surviving fetal neural transplants that developed mass lesions

scientific article published on 05 December 2008

A randomized placebo-controlled pilot trial of omega-3 fatty acids and alpha lipoic acid in Alzheimer's disease

scientific article published on January 2014

ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology

scientific article

ADAM10 expression and promoter haplotype in Alzheimer's disease

scientific article

AI-enabled <i>in silico</i> immunohistochemical characterization for Alzheimer's disease

scientific article published on 28 March 2022

APOE genotype-dependent modulation of astrocyte chemokine CCL3 production.

scientific article published on 4 August 2014

APOE mRNA and protein expression in postmortem brain are modulated by an extended haplotype structure

scientific article

APOE ε4 increases risk for dementia in pure synucleinopathies

scientific article published on February 2013

APOE, MAPT, and SNCA genes and cognitive performance in Parkinson disease

scientific article

APOE3, but not APOE4, bone marrow transplantation mitigates behavioral and pathological changes in a mouse model of Alzheimer disease

scientific article published on 4 July 2013

Aberrant detergent-insoluble excitatory amino acid transporter 2 accumulates in Alzheimer disease.

scientific article

Ablation of the microglial protein DOCK2 reduces amyloid burden in a mouse model of Alzheimer's disease.

scientific article published on 11 January 2013

Abnormal gephyrin immunoreactivity associated with Alzheimer disease pathologic changes

scientific article

Absence of C9ORF72 expanded or intermediate repeats in autopsy-confirmed Parkinson's disease

scientific article

Adult Changes in Thought study: dementia is an individually varying convergent syndrome with prevalent clinically silent diseases that may be modified by some commonly used therapeutics

scientific article

Advanced glycation endproduct precursor alters intracellular amyloid-beta/A beta PP carboxy-terminal fragment aggregation and cytotoxicity

scientific article published on December 2003

Age-dependent changes in the cerebrospinal fluid proteome by slow off-rate modified aptamer array

scientific article

Aggregates of small nuclear ribonucleic acids (snRNAs) in Alzheimer's disease.

scientific article

Aging, gender and APOE isotype modulate metabolism of Alzheimer's Abeta peptides and F-isoprostanes in the absence of detectable amyloid deposits.

scientific article published in August 2004

Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy

scientific article published on 10 December 2015

Alternative processing of γ-secretase substrates in common forms of mild cognitive impairment and Alzheimer's disease: evidence for γ-secretase dysfunction

scientific article

Alzheimer's Disease Sequencing Project discovery and replication criteria for cases and controls: Data from a community-based prospective cohort study with autopsy follow-up

scientific article

An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues

An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues.

scientific article published on 28 August 2017

Analysis of alpha-synuclein-associated proteins by quantitative proteomics

scientific article published in July 2004

Anatomic and clinical pathology of cognitive impairment and dementia

scientific article published on January 2013

Antagonism of neuronal prostaglandin E(2) receptor subtype 1 mitigates amyloid β neurotoxicity in vitro

scientific article

Antioxidants for Alzheimer disease: a randomized clinical trial with cerebrospinal fluid biomarker measures

scientific article published on July 2012

Antioxidants significantly affect the formation of different classes of isoprostanes and neuroprostanes in rat cerebral synaptosomes

scientific article

Apolipoprotein C-I is an APOE genotype-dependent suppressor of glial activation

scientific article

Apolipoprotein E allelic influence on human cerebrospinal fluid apolipoproteins.

scientific article published in December 1998

Apolipoprotein E isoform-dependent dendritic recovery of hippocampal neurons following activation of innate immunity

scientific article

Apolipoprotein E isoform-dependent microglia migration

scientific article

Apolipoprotein E isoforms and apolipoprotein AI protect from amyloid precursor protein carboxy terminal fragment-associated cytotoxicity

scientific article

Apolipoprotein E isoforms and regulation of the innate immune response in brain of patients with Alzheimer's disease

scientific article

Apolipoprotein E-specific innate immune response in astrocytes from targeted replacement mice

scientific article published on 7 April 2006

Apolipoprotein E-ε4 increases the risk for dementia in the ‘pure’ synucleopathies

scholarly article by Debby Tsuang et al published July 2012 in Alzheimer's and Dementia

Application of targeted quantitative proteomics analysis in human cerebrospinal fluid using a liquid chromatography matrix-assisted laser desorption/ionization time-of-flight tandem mass spectrometer (LC MALDI TOF/TOF) platform

scientific article

Application of the condensed protocol for the NIA-AA guidelines for the neuropathological assessment of Alzheimer's disease in an academic clinical practice

scientific article

Arterial spin labeling detects perfusion patterns related to motor symptoms in Parkinson's disease

scientific article published on 11 May 2020

Association Between Sepsis and Microvascular Brain Injury

scientific article published on 01 November 2019

Association between Cholesterol Exposure and Neuropathological Findings: The ACT Study

scientific article published on 19 July 2017

Association between lifetime cigarette smoking and lewy body accumulation

scientific article

Association of GBA Mutations and the E326K Polymorphism With Motor and Cognitive Progression in Parkinson Disease

scientific article published on 29 August 2016

Association of HFE mutations with neurodegeneration and oxidative stress in Alzheimer's disease and correlation with APOE ⬇️

scientific article published on May 15, 2003

Association of Traumatic Brain Injury With Late-Life Neurodegenerative Conditions and Neuropathologic Findings

scientific article published on 11 July 2016

Association of cognitive domains with postural instability/gait disturbance in Parkinson's disease.

scientific article published on 14 April 2015

Associations between Use of Specific Analgesics and Concentrations of Amyloid-β 42 or Phospho-Tau in Regions of Human Cerebral Cortex.

scientific article published on 8 December 2017

Associations between microinfarcts and other macroscopic vascular findings on neuropathologic examination in 2 databases

scientific article

Attention Network Test fMRI data for participants with Parkinson's disease and healthy elderly

scientific article published on 04 June 2019

Attenuated progression of diet-induced steatohepatitis in glutathione-deficient mice

scientific article published on 14 June 2010

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 01 September 2019

Aβ Imaging: feasible, pertinent, and vital to progress in Alzheimer's disease

scientific article published in February 2012

Biomarkers for Alzheimer’s disease

scientific article published on 01 August 2007

Biomarkers for cognitive impairment and dementia in elderly people.

scientific article

Biomarkers of oxidative damage and inflammation in Alzheimer's disease

scientific article

Blood pressure and brain injury in older adults: findings from a community-based autopsy study.

scientific article

CNS tau efflux via exosomes is likely increased in Parkinson's disease but not in Alzheimer's disease

scientific article published on 24 May 2016

COllaborative Neuropathology NEtwork Characterizing ouTcomes of TBI (CONNECT-TBI)

scientific article published in March 2021

CSF Aβ(42) and tau in Parkinson's disease with cognitive impairment.

scientific article

CSF lipoproteins and Alzheimer's disease

scientific article

CSF multianalyte profile distinguishes Alzheimer and Parkinson diseases

scientific article published on April 2008

CSF tau/Abeta42 ratio for increased risk of mild cognitive impairment: a follow-up study

scientific article published on 14 August 2007

Carbofuran-induced oxidative stress in slow and fast skeletal muscles: prevention by memantine and atropine

scientific article published in March 2005

Carbonyl toxicology and Alzheimer's disease

scientific article

Catalysis of catechol oxidation by metal-dithiocarbamate complexes in pesticides

scientific article

Central nervous system lipoproteins in Alzheimer's disease

scientific article published on December 1997

Cerebral cortical Aβ42 and PHF-τ in 325 consecutive brain autopsies stratified by diagnosis, location, and APOE.

scientific article

Cerebrospinal Fluid Particles in Alzheimer Disease and Parkinson Disease

scientific article

Cerebrospinal Fluid Total Tau is Increased in Normal Pressure Hydrocephalus Patients who Undergo Successful Lumbar Drain Trials

scientific article

Cerebrospinal fluid Aβ42 levels and APP processing pathway genes in Parkinson's disease

scientific article published on 24 March 2015

Cerebrospinal fluid F2-isoprostane levels are increased in Alzheimer's disease

scientific article published in September 1998

Cerebrospinal fluid F2-isoprostanes are elevated in Huntington's disease

scientific article published in March 1999

Cerebrospinal fluid abeta42, tau, and f2-isoprostane concentrations in patients with Alzheimer disease, other dementias, and in age-matched controls

scientific article published in April 2001

Cerebrospinal fluid biomarkers and cognitive performance in non-demented patients with Parkinson's disease.

scientific article

Cerebrospinal fluid biomarkers for Alzheimer's and vascular disease vary by age, gender, and APOE genotype in cognitively normal adults

scientific article

Cerebrospinal fluid biomarkers for Parkinson disease diagnosis and progression

scientific article

Cerebrospinal fluid biomarkers in mild cognitive impairment and dementia

scientific article

Cerebrospinal fluid concentration of brain-derived neurotrophic factor and cognitive function in non-demented subjects

scientific article

Cerebrospinal fluid lipoprotein delivery to human neuronal cells is increased in Alzheimer's disease and is dependent on apoE monomer concentration

scientific article

Cerebrospinal fluid lipoproteins are more vulnerable to oxidation in Alzheimer's disease and are neurotoxic when oxidized ex vivo

scientific article

Cerebrospinal fluid lipoproteins in Alzheimer's disease

scientific article

Characterization of cognitive impairments and neurotransmitter changes in a novel transgenic mouse lacking Slc10a4

scientific article published on 18 March 2016

Characterization of proteome of human cerebrospinal fluid

scientific article

Characterizing Apolipoprotein E ε4 Carriers and Noncarriers With the Clinical Diagnosis of Mild to Moderate Alzheimer Dementia and Minimal β-Amyloid Peptide Plaques

scientific article published on 24 August 2015

Chronic dietary alpha-lipoic acid reduces deficits in hippocampal memory of aged Tg2576 mice

scientific article published on 31 January 2006

Clinical-pathologic correlations in vascular cognitive impairment and dementia

scientific article published on 28 August 2015

Co-morbidity of TDP-43 proteinopathy in Lewy body related diseases

scientific article

Cognitive Correlates of MRI-defined Cerebral Vascular Injury and Atrophy in Elderly American Indians: The Strong Heart Study

scientific article published on 03 December 2019

Cognitive Impairment in Older Adults and Therapeutic Strategies

scientific article published on 01 January 2021

Cognitive Performance in Parkinson's Disease in the Brain Health Registry

article

Cognitive associations with comprehensive gait and static balance measures in Parkinson's disease

scientific article published on 04 July 2019

Cognitive impairment and dementia in patients with Parkinson disease.

scientific article published on January 2009

Cognitive impairment in older adults without dementia: clinical and pathologic outcomes in a community-based sample

scientific article published on 11 May 2009

Cognitive profile of LRRK2-related Parkinson's disease

scientific article

Common variant rs356182 near SNCA defines a Parkinson's disease endophenotype

scientific article

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

scientific article

Comparative sensitivity of the MoCA and Mattis Dementia Rating Scale-2 in Parkinson's disease

scientific article published on 10 December 2018

Comparison of regional flortaucipir PET with quantitative tau immunohistochemistry in three subjects with Alzheimer's disease pathology: a clinicopathological study

scientific article published on 15 June 2020

Complement 3 and factor h in human cerebrospinal fluid in Parkinson's disease, Alzheimer's disease, and multiple-system atrophy

scientific article

Concepts for brain aging: resistance, resilience, reserve, and compensation

scientific article published on 11 March 2019

Correlation of Alzheimer disease neuropathologic changes with cognitive status: a review of the literature

scientific article published on May 2012

Cortical serotonin and norepinephrine denervation in parkinsonism: preferential loss of the beaded serotonin innervation.

scientific article published on July 2009

Covalent crosslinking of neurofilament proteins by oxidized catechols as a potential mechanism of Lewy body formation

scientific article published on 01 May 1995

Cross-sectional and longitudinal relationships between cerebrospinal fluid biomarkers and cognitive function in people without cognitive impairment from across the adult life span

scientific article

Crosslinking of apolipoprotein E by products of lipid peroxidation.

scientific article published in February 1996

Cysteine and mercapturate conjugates of oxidized dopamine are in human striatum but only the cysteine conjugate impedes dopamine trafficking in vitro and in vivo

scientific article published in November 2001

DJ-1 and alpha-synuclein in human cerebrospinal fluid as biomarkers of Parkinson's disease

scientific article

DJ-1 isoforms in whole blood as potential biomarkers of Parkinson disease

scientific article

DOCK2 is a microglial specific regulator of central nervous system innate immunity found in normal and Alzheimer's disease brain.

scientific article published on 03 September 2009

Deletion of the prostaglandin E2 EP2 receptor reduces oxidative damage and amyloid burden in a model of Alzheimer's disease.

scientific article published in November 2005

Dendritic degeneration in neostriatal medium spiny neurons in Parkinson disease

scientific article

Detection of biomarkers with a multiplex quantitative proteomic platform in cerebrospinal fluid of patients with neurodegenerative disorders.

scientific article

Detergent-insoluble EAAC1/EAAT3 aberrantly accumulates in hippocampal neurons of Alzheimer's disease patients

scientific article published on 02 July 2008

Diagnosis and management of dementia with Lewy bodies: Fourth consensus report of the DLB Consortium

scientific article

Diagnostic Values of Cerebrospinal Fluid T-Tau and Aβ₄₂ using Meso Scale Discovery Assays for Alzheimer's Disease

scientific article

Dialkyldithiocarbamates inhibit tyrosine hydroxylase activity in PC12 cells and in fibroblasts that express tyrosine hydroxylase

scientific article published on 01 September 1995

Diet intervention and cerebrospinal fluid biomarkers in amnestic mild cognitive impairment

scientific article published in June 2011

Different mechanisms of apolipoprotein E isoform-dependent modulation of prostaglandin E2 production and triggering receptor expressed on myeloid cells 2 (TREM2) expression after innate immune activation of microglia

scientific article published on 15 January 2015

Different patterns of cerebral injury in dementia with or without diabetes

scientific article published on 12 January 2009

Digestion products of the PH20 hyaluronidase inhibit remyelination

scientific article published on February 2013

Diminished taxol/GTP-stimulated tubulin polymerization in diseased region of brain from patients with late-onset or inherited Alzheimer's disease or frontotemporal dementia with parkinsonism linked to chromosome-17 but not individuals with mild cogn

scientific article

Distribution of reducible 4-hydroxynonenal adduct immunoreactivity in Alzheimer disease is associated with APOE genotype

scientific article published on May 1998

Does Data-Independent Acquisition Data Contain Hidden Gems? A Case Study Related to Alzheimer's Disease

scientific article published on 24 November 2021

Dopamine mercapturate can augment dopaminergic neurodegeneration

scientific article

Dopamine thioethers in neurodegeneration

scientific article

Dopamine thioethers: Formation in brain and neurotoxicity ⬇️

scientific article published on November 1, 2002

E-4-hydroxy-2-nonenal is cytotoxic and cross-links cytoskeletal proteins in P19 neuroglial cultures

scientific article published on January 1996

Ecology of the aging human brain

scientific article published on August 2011

Effect of Dopaminergic Medications on Blood Oxygen Level-Dependent Variability and Functional Connectivity in Parkinson's Disease and Healthy Aging

scientific article published on 01 September 2019

Effect of apolipoprotein E genotype and diet on apolipoprotein E lipidation and amyloid peptides: randomized clinical trial

scientific article

Effect of statins on Alzheimer's disease biomarkers in cerebrospinal fluid.

scientific article published in December 2006

Effects of Regular and Long-Acting Insulin on Cognition and Alzheimer's Disease Biomarkers: A Pilot Clinical Trial

scientific article

Effects of chemical chaperones on oxidative stress and detergent-insoluble species formation following conditional expression of amyloid precursor protein carboxy-terminal fragment

scientific article published on 30 November 2006

Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study

scientific article

Effects of reactive gamma-ketoaldehydes formed by the isoprostane pathway (isoketals) and cyclooxygenase pathway (levuglandins) on proteasome function

scientific article

Eicosanoid receptor subtype-mediated opposing regulation of TLR-stimulated expression of astrocyte glial-derived neurotrophic factor

scientific article

Electrophilic cyclopentenone neuroprostanes are anti-inflammatory mediators formed from the peroxidation of the omega-3 polyunsaturated fatty acid docosahexaenoic acid

scientific article

Elevated CSF prostaglandin E2 levels in patients with probable AD

scientific article published on 01 October 1999

Elevated CSF prostaglandin E2 levels in patients with probable AD.

scientific article published in July 2000

Elevated ratio of urinary metabolites of thromboxane and prostacyclin is associated with adverse cardiovascular events in ADAPT

scientific article

Elevation of AKR7A2 (succinic semialdehyde reductase) in neurodegenerative disease

scientific article

Empiric refinement of the pathologic assessment of Lewy-related pathology in the dementia patient

scientific article published on 29 January 2008

Endogenous catechol thioethers may be pro-oxidant or antioxidant.

scientific article published on 01 August 1999

Enhancement of dopaminergic neurotoxicity by the mercapturate of dopamine: relevance to Parkinson's disease

scientific article

Epigenetic signature and enhancer activity of the human APOE gene.

scientific article

Evaluation of mild cognitive impairment subtypes in Parkinson's disease.

scientific article

Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study

scientific article published on 03 February 2020

Exposure to Strong Anticholinergic Medications and Dementia-Related Neuropathology in a Community-Based Autopsy Cohort

scientific article published on 01 January 2018

Extended results of the Alzheimer's disease anti-inflammatory prevention trial

scientific article

F(2)-isoprostanes as biomarkers of late-onset Alzheimer's disease.

scientific article published on September 2007

F2-dihomo-isoprostanes arise from free radical attack on adrenic acid

scientific article published on 4 February 2008

F2-isoprostanes in Alzheimer and other neurodegenerative diseases

scientific article

Familial prion disease with Alzheimer disease-like tau pathology and clinical phenotype

scientific article

Fatty acid oxidation in the pathogenesis of Alzheimer's disease

scientific article

Fibroblasts that express aromatic amino acid decarboxylase have increased sensitivity to the synergistic cytotoxicity of L-dopa and manganese

scientific article published on September 1994

Flow cytometric evaluation of crude synaptosome preparation as a way to study synaptic alteration in neurodegenerative diseases

scientific article published on 22 September 2018

Flow cytometry analysis of synaptosomes from post-mortem human brain reveals changes specific to Lewy body and Alzheimer's disease.

scientific article

Formation of highly reactive A-ring and J-ring isoprostane-like compounds (A4/J4-neuroprostanes) in vivo from docosahexaenoic acid

scientific article

Formation of isoprostane-like compounds (neuroprostanes) in vivo from docosahexaenoic acid

scientific article published in May 1998

Formation of novel D-ring and E-ring isoprostane-like compounds (D4/E4-neuroprostanes) in vivo from docosahexaenoic acid

scientific article published on March 2000

Formation of novel D-ring and E-ring isoprostane-like compounds (D4/E4-neuroprostanes) in vivo from docosahexaenoic acid

scientific article published in January 2002

Formation of novel isoprostane-like compounds from docosahexaenoic acid

scientific article published on 01 January 1999

Fragile X gene premutation in multiple system atrophy.

scientific article published in December 2004

Free radical damage to cerebral cortex in Alzheimer's disease, microvascular brain injury, and smoking

scientific article published on February 2009

Free radical-mediated damage to brain in Alzheimer's disease and its transgenic mouse models

scientific article published on 24 April 2008

GBA Variants are associated with a distinct pattern of cognitive deficits in Parkinson's disease

scientific article

GBA mutations increase risk for Lewy body disease with and without Alzheimer disease pathology

scientific article

Gene-based GWAS and biological pathway analysis of the resilience of executive functioning

scientific article published on March 2014

Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease

scientific article

Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting

Genetic architecture of resilience of executive functioning

scientific article published on December 2012

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 28 February 2019

Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias

scientific article

Genome-wide association study and functional validation implicates JADE1 in tauopathy

scientific article published on 01 November 2021

Genome-wide brain DNA methylation analysis suggests epigenetic reprogramming in Parkinson disease

scientific article published on 24 June 2019

Genome-wide pleiotropy analysis of neuropathological traits related to Alzheimer's disease

scientific article published on 20 February 2018

Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries, 1990-2013: quantifying the epidemiological transition

journal article published in 2015

Glucocerebrosidase Deficiency in Drosophila Results in α-Synuclein-Independent Protein Aggregation and Neurodegeneration

scientific article

Glucose levels and risk of dementia

scientific article

Glucose levels during life and neuropathologic findings at autopsy among people never treated for diabetes.

scientific article published in August 2016

Glycoproteomics in neurodegenerative diseases

scientific article

Group comparison of spatiotemporal dynamics of intrinsic networks in Parkinson's disease

scientific article

Guidelines for the standardization of preanalytic variables for blood-based biomarker studies in Alzheimer's disease research

scientific article

HIV associated neurodegeneration requires p53 in neurons and microglia

scientific article published on 20 May 2004

Hallucinations and Development of Dementia in Parkinson's Disease

scientific article published on 27 July 2020

Herpes simplex virus type 1 encephalitis is associated with elevated levels of F2-isoprostanes and F4-neuroprostanes

scientific article

High-intensity physical activity modulates diet effects on cerebrospinal amyloid-β levels in normal aging and mild cognitive impairment.

scientific article published on January 2012

High-pressure liquid chromatography quantitation of cytochrome c using 393 nm detection

scientific article

Homocysteine and cognitive function in Parkinson's disease.

scientific article

Human Striatal Dopaminergic and Regional Serotonergic Synaptic Degeneration with Lewy Body Disease and Inheritance of APOE ε4.

scientific article

Human, but not bovine, oxidized cerebral spinal fluid lipoproteins disrupt neuronal microtubules

scientific article published in November 2000

Hydroxynonenal adducts indicate a role for lipid peroxidation in neocortical and brainstem Lewy bodies in humans

scientific article published in February 2002

Hyperinsulinemia provokes synchronous increases in central inflammation and beta-amyloid in normal adults

scientific article

Identification of glutathione S-transferase pi as a protein involved in Parkinson disease progression

scientific article

Immunohistochemical and biochemical studies demonstrate a distinct profile of alpha-synuclein permutations in multiple system atrophy

scientific article

Immunohistochemical detection of 4-hydroxy-2-nonenal adducts in Alzheimer's disease is associated with inheritance of APOE4.

scientific article published on February 1997

Importance of home study visit capacity in dementia studies

scientific article published on 18 November 2015

Improved assay for the quantification of the major urinary metabolite of the isoprostane 15-F(2t)-Isoprostane (8-iso-PGF(2alpha)) by a stable isotope dilution mass spectrometric assay

scientific article published in December 2001

In vivo assessment of lipid peroxidation products associated with age-related neurodegenerative diseases

scientific article

Increased CSF E-Selectin in Clinical Alzheimer's Disease without Altered CSF Aβ42 and Tau.

scientific article published in August 2015

Increased CSF F2-isoprostane concentration in probable AD.

scientific article published in February 1999

Increased cerebral cortical lipid peroxidation and abnormal phospholipids in aged homozygous apoE-deficient C57BL/6J mice

scientific article published in July 1999

Increased cerebrospinal fluid F2-isoprostanes are associated with aging and latent Alzheimer's disease as identified by biomarkers

scientific article published on 15 July 2010

Inflammation and cerebral amyloidosis are disconnected in an animal model of Alzheimer's disease

scientific article published in April 2003

Inflammatory prostaglandin E2 signaling in a mouse model of Alzheimer disease.

scientific article

Influence of lifestyle modifications on age-related free radical injury to brain

scientific article

Interactions between apolipoprotein E gene and dietary alpha-tocopherol influence cerebral oxidative damage in aged mice.

scientific article published in August 2001

Intranasal insulin therapy for Alzheimer disease and amnestic mild cognitive impairment: a pilot clinical trial

scientific article published on 12 September 2011

Isoprostanes and related products of lipid peroxidation in neurodegenerative diseases.

scientific article published on March 2004

LR11/SorLA expression is reduced in sporadic Alzheimer disease but not in familial Alzheimer disease

scientific article published on September 2006

Lack of beta-methylamino-l-alanine in brain from controls, AD, or Chamorros with PDC.

scientific article

Large-scale exploratory genetic analysis of cognitive impairment in Parkinson's disease

scientific article published on 20 April 2017

Large-scale proteomic analysis of Alzheimer's disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation

scientific article published on 13 April 2020

Lewy body pathology in familial Alzheimer disease: evidence for disease- and mutation-specific pathologic phenotype

scientific article published in March 2006

Lewy body pathology in late-onset familial Alzheimer's disease: a clinicopathological case series.

scientific article published in August 2006

Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report.

scientific article published in June 2019

Lipid peroxidation in aging brain and Alzheimer's disease

scientific article

Lipoproteins and lipid peroxidation in Alzheimer's disease

scientific article

Liquid chromatography with tandem mass spectrometry-based proteomic discovery in aging and Alzheimer's disease

scientific article published on July 2006

Low plasma leptin in cognitively impaired ADNI subjects: gender differences and diagnostic and therapeutic potential

scientific article

MIBI-TOF: A multiplexed imaging platform relates cellular phenotypes and tissue structure

scientific article published on 09 October 2019

Male microchimerism in the human female brain

scientific article published in 2012

Manganese ethylene-bis-dithiocarbamate and selective dopaminergic neurodegeneration in rat: a link through mitochondrial dysfunction

scientific article

Mass synaptometry: High-dimensional multi parametric assay for single synapses

scientific article published on 20 November 2018

Measurement of isoprostanes as markers of oxidative stress

scientific article published on January 2011

Mechanisms of 4-hydroxynonenal-induced neuronal microtubule dysfunction

scientific article

Memory, mood, and vitamin D in persons with Parkinson's disease

scientific article published on January 2013

Mercapturate metabolism of 4-hydroxy-2-nonenal in rat and human cerebrum

scientific article

Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes

scientific article

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

scientific article

MicroRNA in Alzheimer's disease: an exploratory study in brain, cerebrospinal fluid and plasma

scientific article published on 03 July 2013

Microglia lacking E Prostanoid Receptor subtype 2 have enhanced Abeta phagocytosis yet lack Abeta-activated neurotoxicity

scientific article

Microglial EP2 as a new target to increase amyloid beta phagocytosis and decrease amyloid beta-induced damage to neurons

scientific article

Microglial EP2 is critical to neurotoxicity from activated cerebral innate immunity

scientific article published in October 2005

Mitochondrial DNA deletions/rearrangements in parkinson disease and related neurodegenerative disorders

scientific article

Mitochondrial DNA mutations increase in early stage Alzheimer disease and are inconsistent with oxidative damage

scientific article published on 17 June 2016

Mitochondrial effects of lipid-derived neurotoxins.

scientific article published on September 2007

Mitochondrial therapeutics in Alzheimer's disease and Parkinson's disease

scientific article published on 29 June 2011

Modulation of microglial innate immunity in Alzheimer's disease by activation of peroxisome proliferator-activated receptor gamma

scientific article

Morphometric analysis in neurodegenerative disorders

scientific article

Mouse cerebral prostaglandins, but not oxidative damage, change with age and are responsive to indomethacin treatment

scientific article published in March 2002

Multiplex immunoassay analysis of cytokines in idiopathic inflammatory myopathy

scientific article published on February 2008

Multiplexed In-cell Immunoassay for Same-sample Protein Expression Profiling.

scientific article

Multisite assessment of NIA-AA guidelines for the neuropathologic evaluation of Alzheimer's disease

scientific article

Multivariate prediction of dementia in Parkinson's disease

scientific article published on 25 August 2020

NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease.

scientific article published in April 2018

National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease

scientific article

National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease: a practical approach

scientific article published on 20 November 2011

Network Analysis of a Membrane-Enriched Brain Proteome across Stages of Alzheimer's Disease

scientific article published on 27 August 2019

Neuronal oxidative damage and dendritic degeneration following activation of CD14-dependent innate immune response in vivo

scientific article

Neuronal oxidative damage from activated innate immunity is EP2 receptor-dependent

scientific article published in October 2002

Neuropathologic changes associated with atrial fibrillation in a population-based autopsy cohort

scientific article published on 28 September 2013

Neuropathologic comorbidity and cognitive impairment in the Nun and Honolulu-Asia Aging Studies

scientific article published on 17 February 2016

Neuropathologic correlates of cognition in a population-based sample

scientific article

Neuropathologic substrates of Parkinson disease dementia

scientific article

Neuropathological Comparison of Adult Onset and Juvenile Huntington's Disease with Cerebellar Atrophy: A Report of a Father and Son.

scientific article published on 11 October 2017

Neuropathological and genetic correlates of survival and dementia onset in synucleinopathies: a retrospective analysis

scientific article

Neuropathological and transcriptomic characteristics of the aged brain.

scientific article

Neuropathology in the adult changes in thought study: a review

scientific article

Neuropathology-based risk scoring for dementia diagnosis in the elderly.

scientific article

Neuropsychologic assessment in collaborative Parkinson's disease research: a proposal from the National Institute of Neurological Disorders and Stroke Morris K. Udall Centers of Excellence for Parkinson's Disease Research at the University of Pennsy

scientific article

Neurotoxicity from innate immune response is greatest with targeted replacement of E4 allele of apolipoprotein E gene and is mediated by microglial p38MAPK.

scientific article published on 15 February 2006

Neurotoxicity of endogenous cysteinylcatechols

scientific article

No difference in plasma or urinary F2-isoprostanes among patients with Huntington's disease or Alzheimer's disease and controls

scientific article published in December 2000

Nonsteroidal anti-inflammatory drugs are associated with increased neuritic plaques

scientific article

Novel antibody capture assay for paraffin-embedded tissue detects wide-ranging amyloid beta and paired helical filament-tau accumulation in cognitively normal older adults.

scientific article

Novel late-onset Alzheimer disease loci variants associate with brain gene expression

scientific article

Oral curcumin for Alzheimer's disease: tolerability and efficacy in a 24-week randomized, double blind, placebo-controlled study

scientific article published on 29 October 2012

Oxidized low-density lipoprotein is present in astrocytes surrounding cerebral infarcts and stimulates astrocyte interleukin-6 secretion

scientific article

PARK10 is a major locus for sporadic neuropathologically confirmed Parkinson disease

scientific article

PART, a distinct tauopathy, different from classical sporadic Alzheimer disease

scientific article

PGH2-derived levuglandin adducts increase the neurotoxicity of amyloid beta1-42

scientific article

Pacific Northwest Udall Center of excellence clinical consortium: study design and baseline cohort characteristics

scientific article published on January 2013

Parkinson's disease is associated with oxidative damage to cytoplasmic DNA and RNA in substantia nigra neurons

scientific article published on May 1999

Parkinson-dementia complex and development of a new stable isotope dilution assay for BMAA detection in tissue

scientific article

Partial depletion of striatal dopamine enhances penetrance of cognitive deficits in a transgenic mouse model of Alzheimer's disease

scientific article published on 30 March 2015

Participant and Study Partner Reported Impact of Cognition on Functional Activities in Parkinson's Disease

scientific article published on 14 December 2019

Pathologic correlates of dementia in individuals with Lewy body disease

scientific article

Pathological correlates of dementia in a longitudinal, population-based sample of aging.

scientific article published in October 2007

People with Parkinson's disease and normal MMSE score have a broad range of cognitive performance

scientific article

Performance of a Condensed Protocol That Reduces Effort and Cost of NIA-AA Guidelines for Neuropathologic Assessment of Alzheimer Disease.

scientific article published on 6 January 2017

Peripheral F2-isoprostanes and F4-neuroprostanes are not increased in Alzheimer's disease

scientific article published in August 2002

Perivascular, but not parenchymal, cerebral engraftment of donor cells after non-myeloablative bone marrow transplantation

scientific article published on 06 April 2013

Pharmacologic inhibition of ROCK2 suppresses amyloid-β production in an Alzheimer's disease mouse model

scientific article published on December 2013

Pharmacologic suppression of neuronal oxidative damage and dendritic degeneration following direct activation of glial innate immunity in mouse cerebrum

scientific article

Pharmacologic suppression of oxidative damage and dendritic degeneration following kainic acid-induced excitotoxicity in mouse cerebrum

scientific article published on 29 April 2008

Plasma apolipoprotein A1 as a biomarker for Parkinson disease

scientific article

Positron Emission Tomography Imaging With [18F]flortaucipir and Postmortem Assessment of Alzheimer Disease Neuropathologic Changes

scientific article published on 27 April 2020

Precision Medicine: Clarity for the Complexity of Dementia.

scientific article published on 24 December 2015

Precision medicine: Clarity for the clinical and biological complexity of Alzheimer's and Parkinson's diseases

scientific article published on May 2015

Predicting lewy body pathology in a community-based sample with clinical diagnosis of Alzheimer's disease

scientific article published in December 2006

Prediction of cognitive progression in Parkinson's disease using three cognitive screening measures

scientific article published on 20 October 2019

Primary age-related tauopathy (PART): a common pathology associated with human aging

scientific article

Primum non nocere: a call for balance when reporting on CTE

scientific article published on 12 February 2019

Prioritized research recommendations from the National Institute of Neurological Disorders and Stroke Parkinson's Disease 2014 conference

scientific article published on 23 September 2014

Prostaglandin E2 receptor subtype 2 (EP2) regulates microglial activation and associated neurotoxicity induced by aggregated alpha-synuclein

scientific article published on 4 January 2007

Prostaglandin E2 receptor subtype 2 regulation of scavenger receptor CD36 modulates microglial Aβ42 phagocytosis

scientific article

Prostaglandin H(2)-derived adducts of proteins correlate with Alzheimer's disease severity

scientific article published on 30 June 2005

Prostaglandin H2 (PGH2) accelerates formation of amyloid beta1-42 oligomers

scientific article

Prostanoid signaling: dual role for prostaglandin E2 in neurotoxicity

scientific article

Proteasomal inhibition induced by manganese ethylene-bis-dithiocarbamate: relevance to Parkinson's disease

scientific article published on January 2004

Protection of hippocampal neurogenesis from toll-like receptor 4-dependent innate immune activation by ablation of prostaglandin E2 receptor subtype EP1 or EP2.

scientific article published on 23 April 2009

Proteomic analysis of neurofibrillary tangles in Alzheimer disease identifies GAPDH as a detergent-insoluble paired helical filament tau binding protein

scientific article

Proteomic biomarker discovery in cerebrospinal fluid for neurodegenerative diseases.

scientific article

Proteomic determination of widespread detergent-insolubility including Abeta but not tau early in the pathogenesis of Alzheimer's disease

scientific article published on 29 August 2005

Proteomic discovery of CSF biomarkers for Alzheimer's disease.

scientific article published in May 2007

Proteomic identification of novel proteins in cortical lewy bodies

scientific article published in April 2007

Proteomic identification of proteins in the human brain: Towards a more comprehensive understanding of neurodegenerative disease

scientific article

Proteomics of human neurodegenerative diseases

scientific article published on October 2008

Quantification of F-ring and D-/E-ring isoprostanes and neuroprostanes in Alzheimer's disease

scientific article published in January 2001

Quantification of F-ring isoprostane-like compounds (F4-neuroprostanes) derived from docosahexaenoic acid in vivo in humans by a stable isotope dilution mass spectrometric assay

scientific article

Quantitation and mapping of cerebral detergent-insoluble proteins in the elderly

scientific article published on 22 July 2008

Quantitative in vivo biomarkers of oxidative damage and their application to the diagnosis and management of Alzheimer's disease.

scientific article

Quantitative proteomic analysis of age-related changes in human cerebrospinal fluid

scientific article published in February 2005

Quantitative proteomic analysis of oligodendrogliomas with and without 1p/19q deletion

scientific article

Quantitative proteomics identifies surfactant-resistant alpha-synuclein in cerebral cortex of Parkinsonism-dementia complex of Guam but not Alzheimer's disease or progressive supranuclear palsy

scientific article

Quantitative proteomics of cerebrospinal fluid from patients with Alzheimer disease.

scientific article published in April 2005

RNA Oxidation in Alzheimer and Parkinson Diseases

scholarly article by AKIHIKO NUNOMURA et al published January 1999 in Rejuvenation Research

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

scientific article

Rarity of the Alzheimer disease-protective APP A673T variant in the United States

scientific article

Reactions of 4-hydroxy-2(E)-nonenal and related aldehydes with proteins studied by carbon-13 nuclear magnetic resonance spectroscopy

scientific article published on 01 April 1998

Recommendations of the Alzheimer's disease-related dementias conference

scientific article

Regulatory region genetic variation is associated with FYN expression in Alzheimer's disease.

scientific article published on 15 November 2016

Relationship between Sensorimotor Inhibition and Mobility in Older Adults with and without Parkinson's Disease

scientific article published on 30 November 2020

Relative contributions of severe dopaminergic neuron ablation and dopamine depletion to cognitive impairment.

scientific article

Reply: LATE to the PART-y

scientific article published on 01 September 2019

Resistance to Alzheimer Disease Neuropathologic Changes and Apparent Cognitive Resilience in the Nun and Honolulu-Asia Aging Studies.

scientific article published on 11 May 2017

Rho-associated protein kinase 1 (ROCK1) is increased in Alzheimer's disease and ROCK1 depletion reduces amyloid-β levels in brain

scientific article published on June 2016

Risk of Transmissibility From Neurodegenerative Disease-Associated Proteins: Experimental Knowns and Unknowns

scientific article published on 01 October 2020

Role of cerebrospinal fluid and plasma biomarkers in the diagnosis of neurodegenerative disorders and mild cognitive impairment

scientific article published on October 2011

Role of glutathione in intracellular amyloid-alpha precursor protein/carboxy-terminal fragment aggregation and associated cytotoxicity

scientific article

Secondary excitotoxicity contributes to dopamine-induced apoptosis of dopaminergic neuronal cultures

scientific article published on July 1998

Seed-competent high-molecular-weight tau species accumulates in the cerebrospinal fluid of Alzheimer's disease mouse model and human patients

scientific article published on 28 June 2016

Selective dendritic degeneration of medium spiny neurons in dementia with Lewy bodies.

scientific article published in May 2006

Selective vulnerability of preterm white matter to oxidative damage defined by F2-isoprostanes

scientific article published in July 2005

Selectively increased oxidative modifications mapped to detergent-insoluble forms of Abeta and beta-III tubulin in Alzheimer's disease

scientific article published in July 2006

Sensorimotor Inhibition and Mobility in Genetic Subgroups of Parkinson's Disease

scientific article published on 04 September 2020

Severely impaired learning and altered neuronal morphology in mice lacking NMDA receptors in medium spiny neurons.

scientific article

Sex differences in progression to mild cognitive impairment and dementia in Parkinson's disease

scientific article published on 9 February 2018

Sex differences in the genetic predictors of Alzheimer's pathology

scientific article published on 01 September 2019

Sex-Specific Association of Apolipoprotein E With Cerebrospinal Fluid Levels of Tau

scientific article published on 01 August 2018

Sex-specific genetic predictors of Alzheimer's disease biomarkers

scientific article published on 02 July 2018

Single-cell epigenomic analyses implicate candidate causal variants at inherited risk loci for Alzheimer's and Parkinson's diseases

scientific article published on 26 October 2020

Single-cell peripheral immunoprofiling of Alzheimer's and Parkinson's diseases

scientific article published on 25 November 2020

Soluble TREM2 is elevated in Parkinson's disease subgroups with increased CSF tau

scientific article published on 01 March 2020

Statin therapy is associated with reduced neuropathologic changes of Alzheimer disease

scientific article

Statin therapy is associated with reduced neuropathologic changes of Alzheimer disease

scientific article published on 01 July 2008

Subjective Cognitive Decline Is Associated With Altered Default Mode Network Connectivity in Individuals With a Family History of Alzheimer's Disease

scholarly article by Sander C.J. Verfaillie et al published May 2018 in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging

Suppressed accumulation of cerebral amyloid {beta} peptides in aged transgenic Alzheimer's disease mice by transplantation with wild-type or prostaglandin E2 receptor subtype 2-null bone marrow

scientific article

Suppressed microglial E prostanoid receptor 1 signaling selectively reduces tumor necrosis factor alpha and interleukin 6 secretion from toll-like receptor 3 activation.

scientific article published on 6 January 2011

Suppression of longitudinal increase in CSF F2-isoprostanes in Alzheimer's disease.

scientific article published in February 2004

Suppression of murine cerebral F2-isoprostanes and F4-neuroprostanes from excitotoxicity and innate immune response in vivo by alpha- or gamma-tocopherol

scientific article published on 19 April 2005

Surgical neuropathology update: a review of changes introduced by the WHO classification of tumours of the central nervous system, 4th edition

scientific article published on June 2008

Susceptibility to neurofibrillary tangles: role of the PTPRD locus and limited pleiotropy with other neuropathologies

scientific article

Synthesis and cellular effects of an intracellularly activated analogue of 4-hydroxynonenal

scientific article published in January 2002

Systems biology approach to late-onset Alzheimer's disease genome-wide association study identifies novel candidate genes validated using brain expression data and Caenorhabditis elegans experiments

scientific article

TARDBP mutations in amyotrophic lateral sclerosis with TDP-43 neuropathology: a genetic and histopathological analysis

scientific article published on 7 April 2008

TDP-43 Neuropathologic Associations in the Nun Study and the Honolulu-Asia Aging Study

scientific article published on 01 January 2018

Tau and 14-3-3 in glial cytoplasmic inclusions of multiple system atrophy

scientific article

Thal Amyloid Stages Do Not Significantly Impact the Correlation Between Neuropathological Change and Cognition in the Alzheimer Disease Continuum.

scientific article

The Alzheimer's Association external quality control program for cerebrospinal fluid biomarkers

scientific article published on July 2011

The Delayed Neuropathological Consequences of Traumatic Brain Injury in a Community-Based Sample

scientific article published on 16 March 2021

The National Institute on Aging and the Alzheimer's Association Research Framework for Alzheimer's disease: Perspectives from the Research Roundtable.

scientific article published in April 2018

The Revised National Alzheimer's Coordinating Center's Neuropathology Form-Available Data and New Analyses

scientific article published on 01 August 2018

The associations among sociocultural factors and neuropsychological functioning in older American Indians: The Strong Heart Study

scientific article published on 25 July 2019

The basis of cellular and regional vulnerability in Alzheimer's disease

scientific article published on 07 August 2019

The future of blood-based biomarkers for Alzheimer's disease

scientific article

The inherent challenges of classifying senescence-Response

scientific article

The lipid peroxidation product 4-hydroxynonenal inhibits neurite outgrowth, disrupts neuronal microtubules, and modifies cellular tubulin.

scientific article published in June 1999

The mitochondrial common deletion in Parkinson's disease and related movement disorders

scientific article published in January 2002

The phosphatase calcineurin regulates pathological TDP-43 phosphorylation.

scientific article published on 29 July 2016

The prostaglandin E2 E-prostanoid 4 receptor exerts anti-inflammatory effects in brain innate immunity

scientific article

The prostaglandin E2 EP2 receptor accelerates disease progression and inflammation in a model of amyotrophic lateral sclerosis

scientific article published on September 2008

The spectrum of mutations in progranulin: a collaborative study screening 545 cases of neurodegeneration

scientific article

The tau tubulin kinases TTBK1/2 promote accumulation of pathological TDP-43

scientific article (publication date: December 2014)

Therapeutic implications of the prostaglandin pathway in Alzheimer's disease

scientific article published on 13 January 2014

Therapeutic targets in prostaglandin E2 signaling for neurologic disease.

scientific article published on January 2008

To help aging populations, classify organismal senescence

scientific article

Total Brain and Hippocampal Volumes and Cognition in Older American Indians: The Strong Heart Study

scientific article published on April 2017

Toward defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

scientific article

Transethnic genome-wide scan identifies novel Alzheimer's disease loci

scientific article published on 6 February 2017

Translational gene mapping of cognitive decline

scientific article published on 14 December 2006

Traumatic brain injury may not increase the risk of Alzheimer disease

scientific article published on 4 October 2017

Treatment of latent stage Alzheimer’s disease with statins?

Treatment with a γ-ketoaldehyde scavenger prevents working memory deficits in hApoE4 mice

scientific article

Type 2 Diabetes, Cognition, and Dementia in Older Adults: Toward a Precision Health Approach

scientific article

Type 2 diabetes and later cognitive function in older American Indians: The Strong Heart Study

scientific article published on 15 April 2019

U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer's disease

scientific article published on 10 September 2013

Unbiased Stereological Analysis of Reactive Astrogliosis to Estimate Age-Associated Cerebral White Matter Injury.

scientific article

Use of Analgesics (Opioids and Nonsteroidal Anti-Inflammatory Drugs) and Dementia-Related Neuropathology in a Community-Based Autopsy Cohort

scientific article published on 25 April 2017

Vasodilator Dysfunction and Oligodendrocyte Dysmaturation in Aging White Matter.

scientific article published on 28 December 2017

Visual hallucinations in dementia: a prospective community-based study with autopsy

scientific article published on April 2009

Visuospatial functioning is associated with sleep disturbance and hallucinations in nondemented patients with Parkinson's disease

scientific article published on 10 June 2019

Washington statewide pathology surveillance for prion disease

scientific article published on 01 April 2007

White matter lesions defined by diffusion tensor imaging in older adults

scientific article

Wild-type bone marrow transplant partially reverses neuroinflammation in progranulin-deficient mice

scientific article published on 8 September 2014

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