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List of works by Ed S Lein

A community-based transcriptomics classification and nomenclature of neocortical cell types

scientific article published on 24 August 2020

A comparative atlas of single-cell chromatin accessibility in the human brain

scientific article published on 12 October 2023

A comprehensive transcriptional map of primate brain development.

scientific article published on 13 July 2016

A machine learning method for the discovery of minimum marker gene combinations for cell type identification from single-cell RNA sequencing

scientific article published on 04 June 2021

A robust ex vivo experimental platform for molecular-genetic dissection of adult human neocortical cell types and circuits.

scientific article

An anatomic gene expression atlas of the adult mouse brain

scientific article published on 15 February 2009

An anatomic transcriptional atlas of human glioblastoma.

scientific article

An anatomically comprehensive atlas of the adult human brain transcriptome

scientific article (publication date: 20 September 2012)

Areal and laminar differentiation in the mouse neocortex using large scale gene expression data

scientific article

Author Correction: Human neocortical expansion involves glutamatergic neuron diversification

scientific article published in 2022

Biallelic mutations in human DCC cause developmental split-brain syndrome.

scientific article

Canonical genetic signatures of the adult human brain

scientific article

Cell type discovery and representation in the era of high-content single cell phenotyping.

scientific article published on 21 December 2017

Cell type discovery using single-cell transcriptomics: implications for ontological representation.

scientific article published on 24 March 2018

Cell types and ontologies of the Human Cell Atlas ⬇️

journal article published in 2021

Cell-type-specific consequences of Reelin deficiency in the mouse neocortex, hippocampus, and amygdala

scientific journal article

Classification of electrophysiological and morphological neuron types in the mouse visual cortex

scientific article published on 17 June 2019

Coexpression networks implicate human midfetal deep cortical projection neurons in the pathogenesis of autism

scientific article

Comments and General Discussion on "The Anatomical Problem Posed by Brain Complexity and Size: A Potential Solution".

scientific article published on 10 June 2016

Common Cell type Nomenclature for the mammalian brain: A systematic, extensible convention ⬇️

journal article from 'arXiv:2006.05406 [q-bio]' published in 2020

Common cell type nomenclature for the mammalian brain

scientific article published on 29 December 2020

Comparative cellular analysis of motor cortex in human, marmoset and mouse

scientific article published on 06 October 2021

Comparative transcriptomics reveals human-specific cortical features

scientific article published on 12 October 2023

Comprehensive cellular-resolution atlas of the adult human brain

scientific article published on 15 July 2016

Comprehensive cellular-resolution atlas of the adult human brain

Comprehensive in situ mapping of human cortical transcriptomic cell types

scientific article published on 24 August 2021

Conserved cell types with divergent features in human versus mouse cortex

scientific article published in 2019 in Nature

Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates

scientific article

Convergent transcriptional specializations in the brains of humans and song-learning birds

scientific article

Correlated gene expression and target specificity demonstrate excitatory projection neuron diversity

scientific article

Cortical fast-spiking parvalbumin interneurons enwrapped in the perineuronal net express the metallopeptidases Adamts8, Adamts15 and Neprilysin

scientific article

Defining a molecular atlas of the hippocampus using DNA microarrays and high-throughput in situ hybridization.

scientific article

Differential connectivity and response dynamics of excitatory and inhibitory neurons in visual cortex.

scientific article published on 17 July 2011

Disruptive CHD8 mutations define a subtype of autism early in development

scientific article

Distinct Transcriptomic Cell Types and Neural Circuits of the Subiculum and Prosubiculum along the Dorsal-Ventral Axis

scientific article published on 01 May 2020

Distinctive Structural and Molecular Features of Myelinated Inhibitory Axons in Human Neocortex

article

Divergent and nonuniform gene expression patterns in mouse brain

scientific article

Evolution and development of the mammalian cerebral cortex

scientific article

Evolution of cellular diversity in primary motor cortex of human, marmoset monkey, and mouse

scientific article published in April 2020

FR-Match: robust matching of cell type clusters from single cell RNA sequencing data using the Friedman-Rafsky non-parametric test

scientific article published on 30 November 2020

Fast assembling of neuron fragments in serial 3D sections.

scientific article published on April 2017

Functional organization of the hippocampal longitudinal axis

scientific article

GENO-32AN ANATOMIC TRANSCRIPTIONAL ATLAS OF GLIOBLASTOMA.

scientific article

Genetic identification of brain cell types underlying schizophrenia

scientific article published on 21 May 2018

Genome-wide atlas of gene expression in the adult mouse brain

scientific article

Genomic anatomy of the hippocampus.

scientific article published in December 2008

Human neocortical expansion involves glutamatergic neuron diversification

scientific article

Hybridization-based in situ sequencing (HybISS) for spatially resolved transcriptomics in human and mouse brain tissue

scientific article published on 29 September 2020

Improving reliability and absolute quantification of human brain microarray data by filtering and scaling probes using RNA-Seq

scientific article

Integrated Morphoelectric and Transcriptomic Classification of Cortical GABAergic Cells ⬇️

scientific article published on 01 November 2020

Integrative functional genomic analysis of human brain development and neuropsychiatric risks

scientific article published on 01 December 2018

Interindividual variation in human cortical cell type abundance and expression

scientific article published on 12 October 2023

Joint registration and synthesis using a probabilistic model for alignment of MRI and histological sections

Large-scale cellular-resolution gene profiling in human neocortex reveals species-specific molecular signatures

scientific article published in April 2012

Molecular and cellular reorganization of neural circuits in the human lineage.

scientific article published in November 2017

Morphoelectric and transcriptomic divergence of the layer 1 interneuron repertoire in human versus mouse neocortex

scientific article published on 12 October 2023

Myelinated inhibitory axons in human neocortex

article

Neurodevelopmental disease genes implicated by de novo mutation and copy number variation morbidity

scientific article published on 17 December 2018

Neuroinformatics for genome-wide 3D gene expression mapping in the mouse brain

scientific article published in July 2007

Neuropathological and transcriptomic characteristics of the aged brain.

scientific article

New developments in sleep research: molecular genetics, gene expression, and systems neurobiology

scientific article

Parallel RNA and DNA analysis after deep sequencing (PRDD-seq) reveals cell type-specific lineage patterns in human brain

scientific article published on 10 June 2020

Patches of disorganization in the neocortex of children with autism

scientific article

Preparation of Acute Brain Slices Using an Optimized N-Methyl-D-glucamine Protective Recovery Method.

scientific article published on 26 February 2018

Publisher Correction: A community-based transcriptomics classification and nomenclature of neocortical cell types

scientific article published on 04 December 2020

Quantitative methods for genome-scale analysis of in situ hybridization and correlation with microarray data

scientific article

STRT-seq-2i: dual-index 5' single cell and nucleus RNA-seq on an addressable microwell array

scientific article published on 27 November 2017

Scaled, high fidelity electrophysiological, morphological, and transcriptomic cell characterization

Shifting the paradigm: new approaches for characterizing and classifying neurons

scientific article published on October 2009

Signature morphoelectric properties of diverse GABAergic interneurons in the human neocortex

scientific article published on 12 October 2023

Single nucleus multi-omics identifies human cortical cell regulatory genome diversity

scientific article published in 2022

Single-Cell Profiling of an In Vitro Model of Human Interneuron Development Reveals Temporal Dynamics of Cell Type Production and Maturation.

scientific article published on March 2017

Single-Cell Profiling of an In Vitro Model of Human Interneuron Development Reveals Temporal Dynamics of Cell Type Production and Maturation.

scientific article published in November 2017

Single-cell DNA methylation and 3D genome architecture in the human brain

scientific article published on 12 October 2023

Single-cell transcriptomic evidence for dense intracortical neuropeptide networks

scientific article published on 11 November 2019

Single-nucleus and single-cell transcriptomes compared in matched cortical cell types

scientific article published in PLoS ONE

Sleep deprivation effects on circadian clock gene expression in the cerebral cortex parallel electroencephalographic differences among mouse strains

scientific article published on July 2008

SmartScope2: Simultaneous Imaging and Reconstruction of Neuronal Morphology.

scientific article published on 24 August 2017

Sparse recurrent excitatory connectivity in the microcircuit of the adult mouse and human cortex

scientific article published on 26 September 2018

Spatial mapping of structural and connectional imaging data for the developing human brain with diffusion tensor imaging

scientific article

Spatiotemporal dynamics of the postnatal developing primate brain transcriptome

scientific article published on 7 May 2015

Surface-based mapping of gene expression and probabilistic expression maps in the mouse cortex

scientific article published on 8 October 2009

The Human Cell Atlas

scientific article

The Human Cell Atlas

The Human Cell Atlas White Paper ⬇️

journal article from 'arXiv:1810.05192 [q-bio]' published in 2018

The complete genome sequence of a Neanderthal from the Altai Mountains

scientific article

The genetic geography of the brain

scientific article published on 01 April 2014

The promise of spatial transcriptomics for neuroscience in the era of molecular cell typing.

scientific article

Transcriptional architecture of the primate neocortex

scientific article published on 21 March 2012

Transcriptional landscape of the prenatal human brain

scientific article

Transcriptomic Perspectives on Neocortical Structure, Development, Evolution, and Disease

scientific article published on 29 June 2017

Transcriptomic and morphophysiological evidence for a specialized human cortical GABAergic cell type

scientific article published on 27 August 2018

Transcriptomic cytoarchitecture reveals principles of human neocortex organization

scientific article published on 12 October 2023

Transcriptomic diversity of cell types across the adult human brain

scientific article published on 12 October 2023

Transcriptomic evidence for dense peptidergic neuromodulation networks in mouse cortex

Transcriptomic evidence that von Economo neurons are regionally specialized extratelencephalic-projecting excitatory neurons

scientific article published on 03 March 2020

Using single nuclei for RNA-seq to capture the transcriptome of postmortem neurons

scientific article

h-Channels Contribute to Divergent Intrinsic Membrane Properties of Supragranular Pyramidal Neurons in Human versus Mouse Cerebral Cortex

scientific article published on 01 November 2018

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