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List of works by Zbigniew Leśnikowski

"Chemical ligation": a versatile method for nucleoside modification with boron clusters

scientific article

2'-deoxyadenosine bearing hydrophobic carborane pharmacophore

scientific article published in January 2007

A nucleoside conjugate containing a metallacarborane group and its incorporation into a DNA oligonucleotide

scientific article published on December 2003

Adenosine and 2'-deoxyadenosine modified with boron cluster pharmacophores as new classes of human blood platelet function modulators

scientific article published in May 2010

Aggregation behavior of nucleoside-boron cluster conjugates in aqueous solutions

scientific article published on 08 February 2008

Anti-mycobacterial activity of thymine derivatives bearing boron clusters

scientific article

Association of TLR3 L412F Polymorphism with Cytomegalovirus Infection in Children

scientific article

Boron Clusters as a Platform for New Materials: Synthesis of Functionalized o-Carborane (C2 B10 H12 ) Derivatives Incorporating DNA Fragments

scientific article published on 8 September 2015

Boron clusters as a platform for new materials: composites of nucleic acids and oligofunctionalized carboranes (C2B10H12) and their assembly into functional nanoparticles

scientific article published on 25 November 2019

Carborane-linked 2'-deoxyuridine 5'-O-triphosphate as building block for polymerase synthesis of carborane-modified DNA.

scientific article published on 30 September 2017

Carboranyl oligonucleotides: 4. synthesis and physicochemical studies of oligonucleotides containing 2'-O-(o-carboran-1-yl)methyl group

scientific article

Challenges and Opportunities for the Application of Boron Clusters in Drug Design

scientific article published on 28 April 2016

Comparative Study of Carborane- and Phenyl-Modified Adenosine Derivatives as Ligands for the A2A and A3 Adenosine Receptors Based on a Rigid in Silico Docking and Radioligand Replacement Assay.

scientific article

Comparative kinetic analyses of interaction of inhibitors with Rauscher murine leukemia virus and human immunodeficiency virus reverse transcriptases

scientific article published on May 1996

Comparative study of inorganic, boron-rich cluster and organic, phenyl adenosine modifications: synthesis and properties

scientific article published on 10 June 2019

Comparative study of the effects of ortho-, meta- and para-carboranes (C2B10H12) on the physicochemical properties, cytotoxicity and antiviral activity of uridine and 2'-deoxyuridine boron cluster conjugates

scientific article published on 29 November 2019

Cytomegalovirus DNA is highly prevalent in the blood of patients with asthma and is associated with age and asthma traits

scientific article published on 22 June 2017

Cytomegalovirus alpha-chemokine genotypes are associated with clinical manifestations in children with congenital or postnatal infections

scientific article published on 5 July 2014

Cytomegalovirus glycoprotein H genotype distribution and the relationship with hearing loss in children

scientific article published on 21 February 2014

DNA Modified with Boron⁻Metal Cluster Complexes [M(C₂B₉H)₂]-Synthesis, Properties, and Applications ⬇️

scientific article published on 07 November 2018

DNA probe modified with 3-iron bis(dicarbollide) for electrochemical determination of DNA sequence of Avian Influenza Virus H5N1.

scientific article published on 21 July 2013

Decrease in 3-nitrotyrosine in the amniotic fluid of women with cytomegalovirus infection

scientific article published on 31 January 2014

Detection of cytomegalovirus in human placental cells by polymerase chain reaction.

scientific article

Diastereomers of thymidine 3'-O-(methanephosphonothioate): synthesis, absolute configuration and reaction with 3'-methoxyacetylthymidine under conditions of triester approach to oligonucleotide synthesis

scientific article published on January 1987

Distribution of UL144, US28 and UL55 genotypes in Polish newborns with congenital cytomegalovirus infections

scientific article

Distribution of cytomegalovirus gN variants and associated clinical sequelae in infants

scientific article published on 25 June 2013

Drugs against human cytomegalovirus

scientific article published in September 2002

EU-OPENSCREEN: A Novel Collaborative Approach to Facilitate Chemical Biology

scientific article published on 07 January 2019

Effect of adenosine modified with a boron cluster pharmacophore on reactive oxygen species production by human neutrophils

scientific article published on 25 September 2012

Electrochemical DNA detection based on the polyhedral boron cluster label

scientific article

Electrochemical detection of DNA hybridization using metallacarborane unit

scientific article published on 04 November 2011

High Boron-loaded DNA-Oligomers as Potential Boron Neutron Capture Therapy and Antisense Oligonucleotide Dual-Action Anticancer Agents

scientific article published on 23 August 2017

Human parainfluenza virus type 3 (HPIV3) induces production of IFNγ and RANTES in human nasal epithelial cells (HNECs).

scientific article

In vitro antileukemic activity of novel adenosine derivatives bearing boron cluster modification

scientific article published on 20 August 2016

Insight into the expression of RIG-I-like receptors in human third trimester placentas following ex vivo cytomegalovirus or vesicular stomatitis virus infection

scientific article published on 20 August 2020

Interactions of Boron Clusters and their Derivatives with Serum Albumin.

scientific article

Metallacarborane Complex Boosts the Rate of DNA Oligonucleotide Hydrolysis in the Reaction Catalyzed by Snake Venom Phosphodiesterase

scientific article published on 05 May 2020

Mixed infections with distinct cytomegalovirus glycoprotein B genotypes in Polish pregnant women, fetuses, and newborns

scientific article

Modification of selected anti-HCMV drugs with lipophilic boron cluster modulator

scientific article published on May 1, 2013

Modulation of human neutrophil activity by adenosine modified with a carborane pharmacophore

scientific article published on 16 May 2014

Nucleoside modification with boron clusters and their metal complexes

scientific article published in September 2009

Nucleoside-metallacarborane conjugates for base-specific metal labeling of DNA

scientific article published on 01 January 2007

Octa(thymidine methanephosphonates) of partially defined stereochemistry: synthesis and effect of chirality at phosphorus on binding to pentadecadeoxyriboadenylic acid

scientific article

Oseltamivir analog with boron cluster modulator

scientific article published on November 1, 2012

P-chiral oligonucleotides. 2D Roesy NMR assignment of absolute configuration at phosphorus and conformational analysis of 5'-O-monomethoxytrityl-(2'-O-deoxyribonucleoside) 3'-O-[O-(4-nitrophenyl)]methanephosphonates

scientific article

Phosphorylation of nucleoside-metallacarborane and carborane conjugates by nucleoside kinases

scientific article

Recent developments with boron as a platform for novel drug design

scientific article published on 15 April 2016

Relationship between toll-like receptor 2 Arg677Trp and Arg753Gln and toll-like receptor 4 Asp299Gly polymorphisms and cytomegalovirus infection

scientific article published on 9 May 2014

Solid state, thermal synthesis of site-specific protein-boron cluster conjugates and their physicochemical and biochemical properties

scientific article published on 20 November 2014

Stereoselective synthesis of P-homochiral oligo(thymidine methanephosphonates).

scientific article published on December 1988

Synthesis and in vitro evaluation of antiviral and cytostatic properties of novel 8-triazolyl acyclovir derivatives

scientific article published on 17 November 2018

Synthesis and the structure of 8-tetrahydrofuronium and 8-tetrahydropyronium derivatives of iron bis(dicarbollide)(-I) and their cleavage reactions

scientific article

Synthesis of lysozyme-metallacarborane conjugates and the effect of boron cluster modification on protein structure and function.

scientific article

TLR9 -1486T/C and 2848C/T SNPs Are Associated with Human Cytomegalovirus Infection in Infants

scientific article

TLR9 2848 GA heterozygotic status possibly predisposes fetuses and newborns to congenital infection with human cytomegalovirus

scientific article

Towards new boron carriers for boron neutron capture therapy: metallacarboranes and their nucleoside conjugates

scientific article published in July 2005

Towards new boron carriers for boron neutron capture therapy: metallacarboranes bearing cobalt, iron and chromium and their cholesterol conjugates

scientific article published on 5 January 2013

Versatile Method for the Site-Specific Modification of DNA with Boron Clusters: Anti-Epidermal Growth Factor Receptor (EGFR) Antisense Oligonucleotide Case.

scientific article published on 7 September 2017

What are the current challenges with the application of boron clusters to drug design?

scientific article published on 28 December 2020

siRNAs modified with boron cluster and their physicochemical and biological characterization

scientific article published on 29 May 2013

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