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List of works by Eng-King Tan

A longitudinal study of non-motor symptom burden in Parkinson's disease after a transition to expert care

scientific article published on 16 May 2015

A multi-centre clinico-genetic analysis of the VPS35 gene in Parkinson disease indicates reduced penetrance for disease-associated variants

scientific article

A sensitive two-photon probe to selectively detect monoamine oxidase B activity in Parkinson's disease models

scientific article published in January 2014

Alpha synuclein promoter and risk of Parkinson's disease: microsatellite and allelic size variability

scientific article published in January 2003

Alpha-synuclein and Parkinson's disease: Implications from the screening of more than 1,900 patients

scholarly article by Daniela Berg et al published 2005 in Movement Disorders

Alpha-synuclein repeat variants and survival in Parkinson's disease

scientific article

An urge to move with L-thyroxine: clinical, biochemical, and polysomnographic correlation

scientific article published in November 2004

Analysis of LINGO1 (rs9652490) polymorphism in sporadic Parkinson's disease in a Polish population, and a meta-analysis

scientific article published in February 2010

Analysis of Lrrk2 R1628P as a risk factor for Parkinson's disease

scientific article

Analysis of non-synonymous-coding variants of Parkinson's disease-related pathogenic and susceptibility genes in East Asian populations

scientific article published on 23 February 2014

Antioxidants inhibit neuronal toxicity in Parkinson's disease-linked LRRK2

scientific article

Association between caffeine intake and risk of Parkinson's disease among fast and slow metabolizers

scientific article published in November 2007

Association of GWAS loci with PD in China ⬇️

scientific article published on January 25, 2011

Association of LRRK2 Haplotype With Age at Onset in Parkinson Disease

scientific article published on 13 November 2017

Botulinum toxin improves quality of life in hemifacial spasm: validation of a questionnaire (HFS-30).

scientific article

COQ2 gene variants associate with cerebellar subtype of multiple system atrophy in Chinese

scientific article published on 16 January 2015

Case Control Polysomnographic Studies of Sleep Disorders in Parkinson's Disease ⬇️

scientific article published on July 22, 2011

Case control MR-CISS and 3D TOF MRA imaging study of medullary compression and hypertension in hemifacial spasm

scientific article published in October 2008

Case-control analysis of LRRK2 protective variants in Essential Tremor

scientific article

Case-control analysis of leucine-rich repeat kinase 2 protective variants in Alzheimer's disease

scientific article

Case-control study of anxiety symptoms in hemifacial spasm

scientific article published in December 2006

Case-control study of restless legs syndrome and quality of sleep in Parkinson's disease

scientific article published on 17 October 2007

Characteristics of Chinese-English bilingual dyslexia in right occipito-temporal lesion

scientific article

Chromosomal deletion at 22q11.2 and Parkinson's disease

scientific article published on 24 March 2016

Clinical characteristics of leg restlessness in Parkinson's disease compared with idiopathic Restless Legs Syndrome

scientific article published on 9 July 2015

Clinically reported heterozygous mutations in the PINK1 kinase domain exert a gene dosage effect

scientific article published on November 2009

Clinicopathological correlation of psychosis and brain vascular changes in Alzheimer's disease

scientific article published on 12 February 2016

Comparing knowledge and attitudes towards genetic testing in Parkinson's disease in an American and Asian population.

scientific article published on 14 December 2006

Comprehensive evaluation of common genetic variation within LRRK2 reveals evidence for association with sporadic Parkinson's disease

scientific article

Considerations of Long-term Pain Evaluation Post-Deep Brain Stimulation Surgery

scientific article published in September 2015

DNAJ mutations are rare in Chinese Parkinson's disease patients and controls.

scientific article

DTI Profiles for Rapid Description of Cohorts at the Clinical-Research Interface

DYT1 mutations amongst adult primary dystonia patients in Singapore with review of literature comparing East and West

scientific article

Deterministic Tractography of the Nigrostriatal-Nigropallidal Pathway in Parkinson's Disease

scientific article

Development of Parkinson’s disease biomarkers ⬇️

scientific article published on December 1, 2010

Dietary cholesterol, fats and risk of Parkinson's disease in the Singapore Chinese Health Study

scientific article published on 10 February 2015

Differential effects of black versus green tea on risk of Parkinson's disease in the Singapore Chinese Health Study

scientific article published on 20 December 2007

Differentiating Non-Motor Symptoms in Parkinson's Disease from Controls and Hemifacial Spasm ⬇️

scientific article published on February 11, 2013

Digit span: a comparison of Chinese versus alphabetic language speakers in dysexecutive dementia patients

scientific article published on 20 August 2013

Dissociative semantic breakdown in Alzheimer's disease: Evidence from multiple category fluency test ⬇️

scientific article published on November 16, 2012

Dopamine D2 receptor TaqIA and TaqIB polymorphisms in Parkinson's disease ⬇️

scientific article published on May 1, 2003

Dopamine agonists and their role in Parkinson's disease treatment

scientific article

Effect of MDR1 haplotype on risk of Parkinson disease

scientific article published in March 2005

Erratum to: Mitochondrial CHCHD-Containing Proteins: Physiologic Functions and Link with Neurodegenerative Diseases

scientific article published on 7 October 2016

Essential tremor and the common LRRK2 G2385R variant

scientific article published on 3 March 2008

Etiologic links between environmental and lifestyle factors and Essential tremor

Evidence of increased odds of essential tremor in Parkinson's disease

scientific article published in May 2008

FUS-linked essential tremor associated with motor dysfunction in Drosophila

scientific article published on 09 July 2016

Familial Parkinson's disease/parkinsonism

scientific article published on 19 April 2015

Flow Cytometry-Based Assessment of Mitophagy Using MitoTracker

scientific article published on 30 March 2016

Functional COMT variant predicts response to high dose pyridoxine in Parkinson's disease

scientific article published in August 2005

Functional parkin promoter polymorphism in Parkinson's disease: New data and meta-analysis ⬇️

scientific article published on December 21, 2010

GSK3β reduces risk of sporadic Parkinson's disease in ethnic Chinese ⬇️

scientific article published on July 19, 2012

GWAS-linked GAK locus in Parkinson’s disease in Han Chinese and meta-analysis ⬇️

scientific article published on December 24, 2011

GWAS-linked PPARGC1A variant in Asian patients with essential tremor

scientific article published on 20 February 2017

Genes and Nonmotor Symptoms in Parkinson's Disease

scientific article published on 14 July 2017

Genetic analysis of CHCHD2 gene in Chinese Parkinson's disease

scientific article published on 14 September 2016

Genetic analysis of DJ-1 in a cohort Parkinson's disease patients of different ethnicity.

scientific article

Genetic analysis of LRRK2 A419V variant in ethnic Chinese.

scientific article

Genetic analysis of SCA 2 and 3 repeat expansions in essential tremor and atypical Parkinsonism

scientific article published in October 2007

Genetic analysis of SCA 27 in ataxia and childhood onset postural tremor

scientific article published in April 2007

Genetic analysis of “leucine‐rich repeat (LRR) and immunoglobulin (Ig) domain‐containing, Nogo receptor‐interacting protein‐1 (LINGO1)” in two independent Chinese parkinson's disease populations ⬇️

scientific article published on October 18, 2010

Genetic association study between STK39 and CCDC62/HIP1R and Parkinson's disease

scientific article

Genetic testing in Parkinson disease: promises and pitfalls

scientific article published on September 2006

Genetic testing of LRRK2 in Parkinson's disease: is there a clinical role?

scientific article published on January 2014

Genetic variations of GAK in two Chinese Parkinson's disease populations: a case-control study

scientific article

Genetics of essential tremor

scientific article published on 14 September 2015

Genome-wide association study of Parkinson's disease in East Asians

scientific article

Global investigation and meta-analysis of the C9orf72 (G4C2)n repeat in Parkinson disease

scientific article

Glucocerebrosidase mutations and risk of Parkinson disease in Chinese patients

scientific article

Greater motor progression in patients with Parkinson disease who carry LRRK2 risk variants.

scientific article

Identification of a common genetic risk variant (LRRK2 Gly2385Arg) in Parkinson's disease

scientific article

Identification of a novel risk variant in the FUS gene in essential tremor

scientific article published in February 2014

Identification of a novel risk variant in the FUS gene in essential tremor

scientific article published on 3 July 2013

Impaired motor imagery in patients with essential tremor: a case control study

scientific article published in March 2007

In vivo evidence of pathogenicity of VPS35 mutations in the Drosophila

scientific article

Induced pluripotent stem cells in Parkinson's disease: scientific and clinical challenges

scientific article

Interaction between SNCA, LRRK2 and GAK increases susceptibility to Parkinson's disease in a Chinese population

scientific article published in March 2015

Interaction between SNCA, LRRK2 and GAK increases susceptibility to Parkinson's disease in a Chinese population.

scientific article

Isolated facial myorhythmia

scientific article published on 29 November 2006

LRRK2 G2019S founder haplotype in the Chinese population

scientific article published in January 2007

Large 3-Mb deletions at 22q11.2 locus in Parkinson's disease and schizophrenia

scientific article published on 27 October 2016

Large-scale replication and heterogeneity in Parkinson disease genetic loci

scientific article

Leucine-rich repeat kinase 2-linked Parkinson's disease: clinical and molecular findings

scientific article

Lingo2 variants associated with essential tremor and Parkinson’s disease ⬇️

scientific article published on February 2, 2011

Linking a genome-wide association study signal to a LRRK2 coding variant in Parkinson's disease

scientific article published on 21 December 2015

Linking restless legs syndrome with Parkinson's disease: clinical, imaging and genetic evidence ⬇️

scientific article published on February 27, 2012

Lrrk2 R1628P in non-Chinese Asian races

scientific article published in October 2008

Lrrk2 R1628P variant is a risk factor for essential tremor

scientific article

MAP1B rescues LRRK2 mutant-mediated cytotoxicity

scientific article

MDPD: an integrated genetic information resource for Parkinson's disease

scientific article published on 23 October 2008

Mitochondrial CHCHD-Containing Proteins: Physiologic Functions and Link with Neurodegenerative Diseases

scientific article published on 8 September 2016

Mitochondrial serine protease HTRA2 gene mutation in Asians with coexistent essential tremor and Parkinson disease

scientific article published on 20 March 2015

Molecular biology changes associated with LRRK2 mutations in Parkinson's disease

scientific article published on July 2008

Molecular targets for modulating the protein translation vital to proteostasis and neuron degeneration in Parkinson's disease

scholarly article by Zhi Dong Zhou et al published 2019 in Translational Neurodegeneration

Movement disorders associated with hyperthyroidism: expanding the phenotype

scientific article published in July 2006

Multiple LRRK2 variants modulate risk of Parkinson disease: a Chinese multicenter study.

scientific article published in May 2010

Mutations in LRRK2 increase phosphorylation of peroxiredoxin 3 exacerbating oxidative stress-induced neuronal death

scientific article

Next-generation sequencing diagnostics for neurological diseases/disorders: from a clinical perspective ⬇️

scientific article published on March 23, 2013

Non-replication of association for six polymorphisms from meta-analysis of genome-wide association studies of Parkinson's disease: large-scale collaborative study

scientific article

Nonmotor symptoms in sporadic versus familial forms of Parkinson's disease

scientific article published on January 2015

Nurr1 mutational screen in Parkinson's disease

scientific article

PARK16 is associated with PD in the Malaysian population

scientific article

Pathogenic mutations in Parkinson disease

scientific article published on July 2007

Pathogenicity of LRRK2 P755L variant in Parkinson's disease

scientific article published in April 2008

Plasma alpha-synuclein detected by single molecule array is increased in PD

Polymorphism of renin-angiotensin system genes in IgA nephropathy

scientific article published in October 2004

Polymorphisms in candidate genes: implications for the current treatment of Parkinson's disease

scientific article

Putaminal Diffusivity Correlates With Disease Progression in Parkinson's Disease: Prospective 6-Year Study

scientific article published on February 2016

Rare lysosomal enzyme gene SMPD1 variant (p.R591C) associates with Parkinson's disease

scientific article

Restless legs syndrome and Parkinson's disease: is there an etiologic link?

scientific article published on December 2006

Resveratrol alleviates MPTP-induced motor impairments and pathological changes by autophagic degradation of α-synuclein via SIRT1-deacetylated LC3.

scientific article published on 14 June 2016

Revisiting the link between hypertension and hemifacial spasm

scientific article published on 19 February 2016

Risk factors for respiratory failure of motor neuron disease in a multiracial Asian population

scientific article published on 12 January 2017

SLC1A2 variant associated with essential tremor but not Parkinson disease in Chinese subjects

scientific article published on 17 April 2013

SNCA rs356219 variant increases risk of sporadic Parkinson's disease in ethnic Chinese ⬇️

scientific article published on June 5, 2013

Severe bruxism following basal ganglia infarcts: insights into pathophysiology

scientific article published in February 2004

Sexual dysfunction is associated with postural instability gait difficulty subtype of Parkinson's disease

scientific article

Sleep and Parkinson's disease: A review of case‐control polysomnography studies ⬇️

scientific article published on October 31, 2012

Spectrum of anxiety symptoms in hyperkinesias

scientific article published in September 2008

Superoxide drives progression of Parkin/PINK1-dependent mitophagy following translocation of Parkin to mitochondria

scientific article published on 12 October 2017

Susceptibility-weighted MRI of extrapyramidal brain structures in Parkinsonian disorders

scientific article published on June 2016

Targeting LRRK2 in Parkinson's disease: an update on recent developments

scientific article

Targeting leucine-rich repeat kinase 2 in Parkinson's disease

scientific article

Test-retest repeatability of assessing environmental and lifestyle factors in Parkinson's disease

scientific article published in May 2008

The association of functional catechol-O-methyltransferase haplotypes with risk of Parkinson's disease, levodopa treatment response, and complications

scientific article published in September 2008

Transcallosal diffusion tensor abnormalities in predominant gait disorder parkinsonism

scientific article published on 22 September 2013

Transducer-based evaluation of tremor

scientific article

Treatment outcome correlates with knowledge of disease in hemifacial spasm

scientific article published on 25 June 2008

Validity of family history in essential tremor

scientific article published on 22 June 2007

Varied pathological and therapeutic response effects associated with CHCHD2 mutant and risk variants

scientific article published on 21 April 2017

Vascular parkinsonism in moyamoya: Microvascular biopsy and imaging correlates

scholarly article by Eng-King Tan et al published 26 November 2003 in Annals of Neurology

p62-Mediated mitochondrial clustering attenuates apoptosis induced by mitochondrial depolarization

scientific article published on 19 April 2017

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