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List of works by Vernice Jackson-Lewis

Adaptive immune neuroprotection in G93A-SOD1 amyotrophic lateral sclerosis mice

scientific article

Adenosine receptor antagonists potentiate dopamine receptor agonist-induced rotational behavior in 6-hydroxydopamine-lesioned rats

scientific article published in June 1993

Alpha-synuclein up-regulation in substantia nigra dopaminergic neurons following administration of the parkinsonian toxin MPTP.

scientific article published on February 2000

Alpha-tocopherol levels in parkinsonian brains

scientific article

An assessment of the validity of densitometric measures of striatal tyrosine hydroxylase-positive fibers: relationship to apomorphine-induced rotations in 6-hydroxydopamine lesioned rats

scientific article published in October 1990

Apoptosis-inducing factor deficiency sensitizes dopaminergic neurons to parkinsonian neurotoxins

scientific article published on August 2010

Autoradiography of dopamine receptors and dopamine uptake sites in the spontaneously hypertensive rat.

scientific article published in November 1990

Bax ablation prevents dopaminergic neurodegeneration in the 1-methyl- 4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease

scientific journal article

Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease.

scientific article published in March 2002

CHOP/GADD153 is a mediator of apoptotic death in substantia nigra dopamine neurons in an in vivo neurotoxin model of parkinsonism

scientific journal article

COX-2 and neurodegeneration in Parkinson's disease.

scientific article

Chronic levodopa or pergolide administration induces down-regulation of dopamine receptors in denervated striatum

scientific article published in September 1984

Classic and New Animal Models of Parkinson's Disease ⬇️

scientific article published on March 28, 2012

Continuous intracerebroventricular infusion of dopamine and dopamine agonists through a totally implanted drug delivery system in animal models of Parkinson's disease

scientific article

Control of mitochondrial integrity in Parkinson's disease

scientific article published in January 2010

Cyclin-dependent kinase 5 is a mediator of dopaminergic neuron loss in a mouse model of Parkinson's disease ⬇️

scientific article published on October 31, 2003

Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegeneration

scholarly article

D-beta-hydroxybutyrate rescues mitochondrial respiration and mitigates features of Parkinson disease

scientific article published in September 2003

DL-threo-DOPS as a precursor of noradrenaline

scientific article published in November 1985

Developmental cell death in dopaminergic neurons of the substantia nigra of mice

scientific article published in August 2000

Differences in nigral neuron number and sensitivity to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in C57/bl and CD-1 mice

scientific article

Effect of Unilateral Perinatal Hypoxic-Ischemic Brain Injury in the Rat on Dopamine D1and D2Receptors and Uptake Sites: A Quantitative Autoradiographic Study ⬇️

scientific article published on December 1, 1991

Effect of unilateral perinatal hypoxic-ischemic brain injury in the rat on striatal muscarinic cholinergic receptors and high-affinity choline uptake sites: a quantitative autoradiographic study

scientific article

Effect of unilateral perinatal hypoxic-ischemic brain injury on striatal dopamine uptake sites and D1 and D2 receptors in adult rats ⬇️

scientific article published on August 19, 1991

Experimental developments in movement disorders: update on proposed free radical mechanisms ⬇️

scientific article published on August 1, 1998

Free radical and nitric oxide toxicity in Parkinson's disease.

scientific article published in January 2003

Glycine involvement in DDT-induced myoclonus

scientific article

Human stem cell-derived spinal cord astrocytes with defined mature or reactive phenotypes

scientific article

Identification of neurodegenerative factors using translatome-regulatory network analysis

scientific article published on 27 July 2015

Inactivation of tyrosine hydroxylase by nitration following exposure to peroxynitrite and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) ⬇️

scientific article published on June 23, 1998

Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease

article

Inhibition of calpains prevents neuronal and behavioral deficits in an MPTP mouse model of Parkinson's disease.

scientific article published in May 2003

L-3-hydroxyacyl-CoA dehydrogenase II protects in a model of Parkinson's disease

scientific article published in July 2004

Lanosterol induces mitochondrial uncoupling and protects dopaminergic neurons from cell death in a model for Parkinson's disease

scientific article published on 5 August 2011

Little effect of dimethyl sulfoxide on blood-brain barrier to dopamine

scientific article published in August 1984

Long-term behavioral and biochemical effects of 6-hydroxydopamine injections in rat caudate-putamen

scientific article

MPTP and SNpc DA neuronal vulnerability: role of dopamine, superoxide and nitric oxide in neurotoxicity. Minireview

scientific article

Mass spectrometric quantification of 3-nitrotyrosine, ortho-tyrosine, and o,o'-dityrosine in brain tissue of 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine-treated mice, a model of oxidative stress in Parkinson's disease.

scientific article

Mechanisms of MPTP toxicity

scientific article published on January 1, 1998

Metabolic correlates of levodopa response in Parkinson's disease

scientific article published in December 2001

Mutant LRRK2(R1441G) BAC transgenic mice recapitulate cardinal features of Parkinson's disease

scientific article

NADPH oxidase mediates oxidative stress in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease ⬇️

scientific article published on April 29, 2003

Neurodegeneration: what is it and where are we?

scientific article

Neuromelanin activates microglia and induces degeneration of dopaminergic neurons: implications for progression of Parkinson's disease

scientific article

Neuronal NOS and cyclooxygenase-2 contribute to DNA damage in a mouse model of Parkinson disease

scientific article published on 17 July 2009

Neuroprotection and neuroregeneration triggered through the FUS-induced opening of the blood-brain barrier in a Parkinson’s mouse model.

scientific article published on 30 June 2015

Oxidative post-translational modifications of alpha-synuclein in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model of Parkinson's disease

scientific article

Persistent penetration of MPTP through the nasal route induces Parkinson's disease in mice

scientific article published in October 2006

Poly(ADP-ribose) polymerase activation mediates 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine (MPTP)-induced parkinsonism

scientific article

Presynaptic inhibition of dopamine synthesis in rat striatum: effects of chronic dopamine depletion and receptor blockade

scientific article published in November 1985

Proteasome inhibition and Parkinson's disease modeling

scientific article published on August 2006

Protocol for the MPTP mouse model of Parkinson's disease

scientific article

Quantitative autoradiographic distribution of [3H]-MPTP binding in the brains of superoxide dismutase transgenic mice

scientific article published in June 1991

Quantitative autoradiographic distribution of [3H]mazindol-labeled dopamine uptake sites in the brains of superoxide dismutase transgenic mice

scientific article published in July 1990

Rapamycin protects against neuron death in in vitro and in vivo models of Parkinson's disease

scientific article

Regional effects of 6-hydroxydopamine (6-OHDA) on free radical scavengers in rat brain

scientific article published on December 1989

Resistance of alpha -synuclein null mice to the parkinsonian neurotoxin MPTP.

scientific article

Role of neuronal nitric oxide in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity

scientific article published on May 1996

Selectively enhanced contextual fear conditioning in mice lacking the transcriptional regulator CCAAT/enhancer binding protein delta

scientific article

Sham transplantation protects against 6-hydroxydopamine-induced dopaminergic toxicity in rats: behavioral and morphological evidence

scientific article published in June 1991

Sonic hedgehog maintains cellular and neurochemical homeostasis in the adult nigrostriatal circuit

scientific article

Striatal 6-hydroxydopamine induces apoptosis of nigral neurons in the adult rat.

scientific article published in December 2002

Superoxide dismutase, catalase, and glutathione peroxidase activities in copper/zinc-superoxide dismutase transgenic mice

scientific article published on May 1992

The MPTP model of Parkinson's disease

scientific article

The Postnatal Development of AMPA Receptor Subunits in the Basal Ganglia of the Rat ⬇️

scientific article published on January 1, 1998

The effect of intracerebroventricular infusion of (+)-4-propyl-9-hydroxynapthoxacine (PHNO) through a totally implanted drug delivery system in rats with dopamine deficiency

scientific article

The effects of chronic bromocriptine treatment on behaviour and dopamine receptor binding in the rat striatum

scientific article published in November 1985

The organic cation transporter-3 is a pivotal modulator of neurodegeneration in the nigrostriatal dopaminergic pathway

scholarly article

The parkinsonian toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): a technical review of its utility and safety

scientific article

The parkinsonian toxin MPTP: action and mechanism.

scientific article published in January 2000

The role of glial cells in Parkinson's disease

scientific article

Therapeutic immunization protects dopaminergic neurons in a mouse model of Parkinson's disease

scholarly article

Transgenic mice with increased Cu/Zn-superoxide dismutase activity are resistant to N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity ⬇️

scientific article published on May 1, 1992

Two molecular pathways initiate mitochondria-dependent dopaminergic neurodegeneration in experimental Parkinson's disease

scholarly article

VMAT2 knockout mice: Heterozygotes display reduced amphetamine-conditioned reward, enhanced amphetamine locomotion, and enhanced MPTP toxicity ⬇️

scientific article published on September 2, 1997

Vitamin E attenuates the toxic effects of intrastriatal injection of 6-hydroxydopamine (6-OHDA) in rats: behavioral and biochemical evidence

scientific article published on January 1989

α-Synuclein-independent histopathological and motor deficits in mice lacking the endolysosomal Parkinsonism protein Atp13a2.

scientific article

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