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List of works by Velia Fowler

A Systems Approach Identifies Essential FOXO3 Functions at Key Steps of Terminal Erythropoiesis

scientific article published on 9 October 2015

A minor actin catastrophe

scientific article published in September 2002

A nebulin ruler does not dictate thin filament lengths

scientific article (publication date: 4 March 2009)

A two-segment model for thin filament architecture in skeletal muscle

scientific article published on 09 January 2013

Aberrant myofibril assembly in tropomodulin1 null mice leads to aborted heart development and embryonic lethality

scientific journal article

Alterations in thin filament length during postnatal skeletal muscle development and aging in mice

scientific article published on 29 September 2014

An actomyosin contractile mechanism for erythrocyte shape transformations

scientific article published on 01 January 1986

Calpain-mediated proteolysis of tropomodulin isoforms leads to thin filament elongation in dystrophic skeletal muscle

scientific article published on 15 January 2014

Capping actin filament growth: tropomodulin in muscle and nonmuscle cells.

scientific article published on January 1997

Caspase remodeling of the spectrin membrane skeleton during lens development and aging.

scientific article

Cell migration without a lamellipodium: translation of actin dynamics into cell movement mediated by tropomyosin

scientific article

Characterization of circulating endothelial cells in acute myocardial infarction

scientific article published on March 2012

Chromaffin granule membrane–F-actin interactions are calcium sensitive

scientific article published in Nature

Congenital myopathy-causing tropomyosin mutations induce thin filament dysfunction via distinct physiological mechanisms.

scientific article

Cytoplasmic gamma-actin and tropomodulin isoforms link to the sarcoplasmic reticulum in skeletal muscle fibers

scientific article

Cytoskeleton

scientific article published on 01 February 1996

Cytoskeleton. New views of the red cell network

scientific article published on 01 August 1986

Defining actin filament length in striated muscle: rulers and caps or dynamic stability?

scientific article published in January 1998

Differential actin-regulatory activities of Tropomodulin1 and Tropomodulin3 with diverse tropomyosin and actin isoforms.

scientific article

Dynamic actin filaments control the mechanical behavior of the human red blood cell membrane

scientific article

Dynamic properties of ankyrin in T lymphocytes: colocalization with spectrin and protein kinase C beta

scientific article

EphA2 and ephrin-A5 are not a receptor-ligand pair in the ocular lens

scientific article

Erythrocyte membrane tropomyosin. Purification and properties

scientific article published on 01 May 1984

Feisty filaments: actin dynamics in the red blood cell membrane skeleton

scientific article published on May 2016

Functional effects of mutations in the tropomyosin-binding sites of tropomodulin1 and tropomodulin3.

scientific article

Generation of an erythrocyte vesicle transport system by Plasmodium falciparum malaria parasites

scientific article published on 17 July 2003

HSPB7 is indispensable for heart development by modulating actin filament assembly

scientific article

High-Resolution Fluorescence Microscope Imaging of Erythroblast Structure.

scientific article published in January 2018

Identification and purification of a novel Mr 43,000 tropomyosin-binding protein from human erythrocyte membranes

scientific article published on 01 September 1987

Identification of a novel tropomodulin isoform, skeletal tropomodulin, that caps actin filament pointed ends in fast skeletal muscle.

scientific article

Isoform-specific interaction of tropomodulin with skeletal muscle and erythrocyte tropomyosins.

scientific article published in November 1994

Leiomodin-3 dysfunction results in thin filament disorganization and nemaline myopathy

scientific article published on 24 September 2014

Lens ion homeostasis relies on the assembly and/or stability of large connexin 46 gap junction plaques on the broad sides of differentiating fiber cells

scientific article published on 4 March 2015

Localization of the human 64kD autoantigen D1 to myofibrils in a subset of extraocular muscle fibers

scientific journal article

Mammalian tropomodulins nucleate actin polymerization via their actin monomer binding and filament pointed end-capping activities.

scientific article

Measurement of thin filament lengths by distributed deconvolution analysis of fluorescence images

scientific article

Mechanisms of thin filament assembly in embryonic chick cardiac myocytes: tropomodulin requires tropomyosin for assembly.

scientific article

Mice lacking Tropomodulin-2 show enhanced long-term potentiation, hyperactivity, and deficits in learning and memory

scientific journal article

Modulation of N-cadherin junctions and their role as epicenters of differentiation-specific actin regulation in the developing lens

scientific article published on 20 October 2010

Myofibrillogenesis in the developing chicken heart: role of actin isoforms and of the pointed end actin capping protein tropomodulin during thin filament assembly

scientific article published in April 2004

Myosin IIA interacts with the spectrin-actin membrane skeleton to control red blood cell membrane curvature and deformability

scientific article published on 02 April 2018

Nebulin: Does It Measure up as a Ruler?

scientific article published on 01 January 2006

Non-uniform distribution of myosin-mediated forces governs red blood cell membrane curvature through tension modulation

scientific article published on 26 May 2020

Pointed-end capping by tropomodulin modulates actomyosin crossbridge formation in skeletal muscle fibers

scientific article

Pointed-end capping by tropomodulin3 negatively regulates endothelial cell motility

scientific article

Proteome-transcriptome analysis and proteome remodeling in mouse lens epithelium and fibers

scientific article published on 22 October 2018

Proteomic and functional analyses of the periodic membrane skeleton in neurons

scientific article published on 09 June 2022

Purification and characterization of an alpha 1 beta 2 isoform of CapZ from human erythrocytes: cytosolic location and inability to bind to Mg2+ ghosts suggest that erythrocyte actin filaments are capped by adducin

scientific article

Rac GTPases regulate the morphology and deformability of the erythrocyte cytoskeleton

scientific article published in August 2006

Regulation of actin filament length in erythrocytes and striated muscle.

scientific article published on February 1996

Regulation of actin polymerization by tropomodulin-3 controls megakaryocyte actin organization and platelet biogenesis

scientific article published on 11 May 2015

Sequential Application of Glass Coverslips to Assess the Compressive Stiffness of the Mouse Lens: Strain and Morphometric Analyses.

scientific article

Software-based measurement of thin filament lengths: an open-source GUI for Distributed Deconvolution analysis of fluorescence images

scientific article published on 19 September 2016

Stabilization of F-actin by tropomyosin isoforms regulates the morphology and mechanical behavior of red blood cells

scientific article published on 18 July 2017

The N-terminal end of nebulin interacts with tropomodulin at the pointed ends of the thin filaments.

scientific article

The effects of mechanical strain on mouse eye lens capsule and cellular microstructure

scientific article published on 10 April 2018

The human erythrocyte plasma membrane: a Rosetta Stone for decoding membrane-cytoskeleton structure

scientific article

The interaction and phosphorylation of tropomodulin by protein kinase Calpha in N/N 1003A lens epithelial cells.

scientific article published on 22 October 2002

The interaction of tropomodulin with tropomyosin stabilizes thin filaments in cardiac myocytes

scientific article

The lens actin filament cytoskeleton: Diverse structures for complex functions

scientific article published on 10 March 2016

The sarcoplasmic reticulum: Actin and tropomodulin hit the links

scientific article

The tropomodulin (Tmod) gene maps to chromosome 4, closely linked to Mup1

scientific article published on 01 May 1995

Thematic Minireview Series: The State of the Cytoskeleton in 2015.

scientific article published on 8 May 2015

Thin filament length regulation in striated muscle sarcomeres: pointed-end dynamics go beyond a nebulin ruler

scientific article published on 26 August 2008

Thin filaments elongate from their pointed ends during myofibril assembly in Drosophila indirect flight muscle.

scientific article

Thyroid-associated ophthalmopathy

scientific article published on 01 October 1994

Tmod1 and CP49 synergize to control the fiber cell geometry, transparency, and mechanical stiffness of the mouse lens

scientific journal article

Tmod3 regulates polarized epithelial cell morphology

scientific article

Tropomodulin 1 Regulation of Actin Is Required for the Formation of Large Paddle Protrusions Between Mature Lens Fiber Cells

scientific article published on August 2016

Tropomodulin 1 constrains fiber cell geometry during elongation and maturation in the lens cortex

scientific article

Tropomodulin 1 controls erythroblast enucleation via regulation of F-actin in the enucleosome

scientific article published on 20 July 2017

Tropomodulin 1 directly controls thin filament length in both wild-type and tropomodulin 4-deficient skeletal muscle.

scientific article

Tropomodulin 1-null mice have a mild spherocytic elliptocytosis with appearance of tropomodulin 3 in red blood cells and disruption of the membrane skeleton

scientific article

Tropomodulin 3 binds to actin monomers

scientific article

Tropomodulin Isoform-Specific Regulation of Dendrite Development and Synapse Formation

article

Tropomodulin and tropomyosin mediate lens cell actin cytoskeleton reorganization in vitro.

scientific article published on January 2000

Tropomodulin binds to filensin intermediate filaments

scientific article published on 01 July 2003

Tropomodulin capping of actin filaments in striated muscle development and physiology

scientific article

Tropomodulin caps the pointed ends of actin filaments

scientific article

Tropomodulin contains two actin filament pointed end-capping domains

scientific article published on 14 July 2003

Tropomodulin function and thin filament assembly in cardiac myocytes.

scientific article published on May 1996

Tropomodulin increases the critical concentration of barbed end-capped actin filaments by converting ADP.P(i)-actin to ADP-actin at all pointed filament ends

scientific article published on 01 December 1999

Tropomodulin isoforms regulate thin filament pointed-end capping and skeletal muscle physiology

scientific journal article

Tropomodulin1 is required for membrane skeleton organization and hexagonal geometry of fiber cells in the mouse lens

scientific article published on 14 September 2009

Tropomodulin1 is required in the heart but not the yolk sac for mouse embryonic development

scientific article published on 16 October 2008

Tropomodulin3-null mice are embryonic lethal with anemia due to impaired erythroid terminal differentiation in the fetal liver

scientific journal article

Tropomodulins and Leiomodins: Actin Pointed End Caps and Nucleators in Muscles

scientific article published on May 2017

Tropomodulins are negative regulators of neurite outgrowth.

scientific article

Tropomodulins: life at the slow end.

scientific article published on November 2003

Tropomodulins: pointed-end capping proteins that regulate actin filament architecture in diverse cell types.

scientific article published on 04 May 2012

Tropomyosin 3.5 protects F-actin networks required for tissue biomechanical properties

scientific article published on 29 November 2018

Tropomyosin is required for cardiac morphogenesis, myofibril assembly, and formation of adherens junctions in the developing mouse embryo

scientific article

Tropomyosin requires an intact N-terminal coiled coil to interact with tropomodulin

scientific article

Tropomyosin: a new component of the erythrocyte membrane skeleton

scientific article published on 01 January 1984