Search filters

List of works by Sheng-Di Chen

A community-based study of risk factors for probable rapid eye movement sleep behavior disorder

scientific article

A complex association of ABCA7 genotypes with sporadic Alzheimer disease in Chinese Han population.

scientific article published in April 2014

A rare family with Hereditary Spastic Paraplegia Type 35 due to novel FA2H mutations: a case report with literature review

scientific article

A single nucleotide polymorphism in LRP2 is associated with susceptibility to Alzheimer's disease in the Chinese population

scientific article published on October 21, 2010

ATP-sensitive potassium channels: novel potential roles in Parkinson's disease

scientific article

Alteration of the fecal microbiota in Chinese patients with Parkinson's disease.

scientific article published in March 2018

Altered regulation of CD200 receptor in monocyte-derived macrophages from individuals with Parkinson's disease

scientific article published on April 2010

Analysis of genome-wide association study-linked loci in Parkinson's disease of Mainland China

scientific article published on 12 July 2013

Analysis of pramipexole dose-response relationships in Parkinson's disease

scientific article published on 23 December 2016

Apolipoprotein E promoter polymorphisms and risk of Alzheimer's disease: evidence from meta-analysis.

scientific article published in January 2010

Application of odor identification test in Parkinson's disease in China: a matched case-control study

scientific article published on 24 February 2012

Association Study of the GAB2 Gene With the Risk of Alzheimer Disease in the Chinese Population

scientific article published on July 1, 2011

Association of Source of Memory Complaints and Increased Risk of Cognitive Impairment and Cognitive Decline: A Community-Based Study.

scientific article

Association of rapid eye movement sleep behavior disorder with sleep-disordered breathing in Parkinson's disease

scientific article

Association study of SCARB2 rs6812193 polymorphism with Parkinson's disease in Han Chinese

scientific article published on March 23, 2012

Association study of clusterin polymorphism rs11136000 with late onset Alzheimer's disease in Chinese Han population

scientific article published in December 2011

Blockade of the translocation and activation of c-Jun N-terminal kinase 3 (JNK3) attenuates dopaminergic neuronal damage in mouse model of Parkinson's disease.

scientific article published on 29 January 2009

CALHM1 P86L polymorphism is a risk factor for Alzheimer's disease in the Chinese population

scientific article published in January 2010

CD200-CD200R dysfunction exacerbates microglial activation and dopaminergic neurodegeneration in a rat model of Parkinson's disease

scientific article published on November 6, 2011

CD200-CD200R regulation of microglia activation in the pathogenesis of Parkinson's disease

scientific article published on 18 May 2007

Chinese culture permeation in the treatment of Parkinson disease: a cross-sectional study in four regions of China

scientific article published on 30 January 2014

Clinical Characteristics for the Relationship between Type-2 Diabetes Mellitus and Cognitive Impairment: A Cross-Sectional Study

scientific article published in August 2015

Clinical Profile of Chinese Long-Term Parkinson's Disease Survivors With 10 Years of Disease Duration and Beyond

scientific article published in February 2018

Clinical profiles of Parkinson's disease associated with common leucine-rich repeat kinase 2 and glucocerebrosidase genetic variants in Chinese individuals

scientific article published on 3 October 2013

Cognitive impairment among elderly individuals in Shanghai suburb, China: association of C-reactive protein and its interactions with other relevant factors

scientific article

Cognitive impairment and associated factors among the elderly in the Shanghai suburb: findings from a low-education population

scientific article

Cognitive impairment and the associated risk factors among the elderly in the Shanghai urban area: a pilot study from China

scientific article published on 26 November 2012

Combination of olfactory test and substantia nigra transcranial sonopraphy in the differential diagnosis of Parkinson's disease: a pilot study from China

scientific article

Computerized cognitive training for Chinese mild cognitive impairment patients: A neuropsychological and fMRI study

article

Corrigendum: Detection of Microbial 16S rRNA Gene in the Blood of Patients With Parkinson's Disease

article

Corrigendum: Diagnostic Value of microRNA for Alzheimer's Disease: A Systematic Review and Meta-Analysis

scientific article published on 23 February 2017

Curcumin ameliorates the neurodegenerative pathology in A53T α-synuclein cell model of Parkinson's disease through the downregulation of mTOR/p70S6K signaling and the recovery of macroautophagy

scientific article published on 17 January 2013

Curcumin could reduce the monomer of TTR with Tyr114Cys mutation via autophagy in cell model of familial amyloid polyneuropathy

scientific article

Curcumin inhibition of JNKs prevents dopaminergic neuronal loss in a mouse model of Parkinson's disease through suppressing mitochondria dysfunction

scientific article

Current Nondopaminergic Therapeutic Options for Motor Symptoms of Parkinson's Disease

scientific article

Current approaches for the management of Parkinson's disease in Chinese hospitals: a cross-sectional survey

article

Current clinical practice for Parkinson's disease among Chinese physicians, general neurologists and movement disorders specialists: a national survey

scientific article

DJ-1 Inhibits α-Synuclein Aggregation by Regulating Chaperone-Mediated Autophagy

scientific article published on 27 September 2017

Dementia among elderly in Shanghai suburb: a rural community survey

scientific article

Depression, anxiety, and quality of life in paroxysmal kinesigenic dyskinesia patients

scientific article

Detection of Microbial 16S rRNA Gene in the Blood of Patients With Parkinson's Disease.

scientific article

Diagnostic Accuracy of Transcranial Sonography of the Substantia Nigra in Parkinson's disease: A Systematic Review and Meta-analysis

scientific article

Diagnostic Value of microRNA for Alzheimer's Disease: A Systematic Review and Meta-Analysis

scientific article

Diffusion Tensor Imaging Changes Correlate with Cognition Better than Conventional MRI Findings in Patients with Subcortical Ischemic Vascular Disease

scientific article published on September 30, 2010

Disrupted Structural Brain Network in AD and aMCI: A Finding of Long Fiber Degeneration

scientific article

Dopaminergic neuroprotection by neurturin-expressing c17.2 neural stem cells in a rat model of Parkinson's disease

scientific article published on 11 September 2006

Dopaminergic regeneration by neurturin-overexpressing c17.2 neural stem cells in a rat model of Parkinson's disease

retracted scientific article

Downregulation of parkin damages antioxidant defenses and enhances proteasome inhibition-induced toxicity in PC12 cells

scientific article published on 20 July 2007

Dysfunction of two lysosome degradation pathways of α-synuclein in Parkinson's disease: potential therapeutic targets?

scientific article published on 08 September 2012

Economic burden of Parkinson's disease in a developing country: a retrospective cost analysis in Shanghai, China

scientific article

Economic impact of dementia in developing countries: an evaluation of Alzheimer-type dementia in Shanghai, China

scientific article published on September 2008

Effect of a Leucine-rich Repeat Kinase 2 Variant on Motor and Non-motor Symptoms in Chinese Parkinson's Disease Patients

scientific article published on 27 May 2016

Effect of transplantation of c17.2 cells transfected with interleukin-10 gene on intracerebral immune response in rat model of Parkinson's disease

scientific article published on 28 June 2007

Efficacy and safety of pramipexole in chinese patients with restless legs syndrome: results from a multi-center, randomized, double-blind, placebo-controlled trial

scientific article published on 3 December 2011

Endoplasmic reticulum stress contributes to the cell death induced by UCH-L1 inhibitor

scientific article

Eriocalyxin B ameliorates experimental autoimmune encephalomyelitis by suppressing Th1 and Th17 cells

scientific article published on 23 January 2013

Excessive Iron and α-Synuclein Oligomer in Brain are Relevant to Pure Apathy in Parkinson Disease

scientific article published on 2 March 2016

Exercise-Related Changes of Networks in Aging and Mild Cognitive Impairment Brain

scientific article

Expression of FasL and its interaction with Fas are mediated by c-Jun N-terminal kinase (JNK) pathway in 6-OHDA-induced rat model of Parkinson disease

scientific journal article

Expression of the gene coading for PGC-1α in peripheral blood leukocytes and related gene variants in patients with Parkinson's disease.

scientific article published on 23 February 2018

Familial Paroxysmal Kinesigenic Dyskinesia is associated with mutations in the KCNA1 gene

scientific article published on 27 December 2017

Familial paroxysmal kinesigenic dyskinesia is associated with mutations in the KCNA1 gene

scientific article

Fatigue correlates with LRRK2 G2385R variant in Chinese Parkinson's disease patients

scientific article

Four novel mutations in the GCH1 gene of Chinese patients with dopa-responsive dystonia

scientific article published in April 2010

Gene polymorphisms and risk of adult early-onset ischemic stroke: A meta-analysis

scientific article

Genetic Features of MAPT, GRN, C9orf72 and CHCHD10 Gene Mutations in Chinese Patients with Frontotemporal Dementia

scientific article published on 25 April 2017

Genetic polymorphisms in sigma-1 receptor and apolipoprotein E interact to influence the severity of Alzheimer's disease

scientific article

Genetic predisposition to inflammation: a new risk factor of Alzheimer's disease

scientific article published on October 2008

Heat shock proteins reduce toxicity of 1-methyl-4-phenylpyridinium ion in SK-N-SH cells

scientific article published on November 2005

History, present, and progress of frontotemporal dementia in china: a systematic review

scientific article published on 25 March 2012

Hyposmia correlates with SNCA variant and non-motor symptoms in Chinese patients with Parkinson's disease

scientific article published on 31 March 2015

Identification of PRRT2 as the causative gene of paroxysmal kinesigenic dyskinesias

scientific article published on November 26, 2011

Identification of glial‐cell‐line‐derived neurotrophic factor‐regulated proteins of striatum in mouse model of Parkinson disease

scientific article published on August 26, 2009

Interictal epileptiform discharges were associated with poorer cognitive performance in adult epileptic patients

scientific article

Investigation on Abnormal Iron Metabolism and Related Inflammation in Parkinson Disease Patients with Probable RBD.

scientific article published on 2 October 2015

Iron deposition in substantia nigra: abnormal iron metabolism, neuroinflammatory mechanism and clinical relevance

scientific article published on 2 November 2017

Kinases and kinase signaling pathways: Potential therapeutic targets in Parkinson's disease

scientific article published on June 16, 2012

Lack of association between ATP13A2 Ala746Thr variant and Parkinson's disease in Han population of mainland China.

scientific article published on 19 March 2010

Lmx1b is essential for Fgf8 and Wnt1 expression in the isthmic organizer during tectum and cerebellum development in mice

scientific journal article

Lmx1b-controlled isthmic organizer is essential for development of midbrain dopaminergic neurons.

scientific article

Malnutrition and associated factors in Chinese patients with Parkinson's disease: Results from a pilot investigation

scientific article published on 23 September 2009

Management Recommendations on Sleep Disturbance of Patients with Parkinson's Disease

scholarly article by Chun-Feng Liu et al published 20 December 2018 in Chinese Medical Journal

Melatonin for sleep disorders and cognition in dementia: a meta-analysis of randomized controlled trials

scientific article published on 22 January 2015

Mental Training for Cognitive Improvement in Elderly People: What have We Learned from Clinical and Neurophysiologic Studies?

scientific article published on January 2015

Metabolomics: a novel approach to identify potential diagnostic biomarkers and pathogenesis in Alzheimer's disease

scientific article published on 03 October 2012

MicroRNA-146a represses LRP2 translation and leads to cell apoptosis in Alzheimer's disease

scientific article

MicroRNA-146a suppresses ROCK1 allowing hyperphosphorylation of tau in Alzheimer's disease

scientific article published on 25 May 2016

Microglia in the aging brain: relevance to neurodegeneration

scientific article

Mitogen activated protein kinase and protein kinase C activation mediate promotion of sAPPalpha secretion by deprenyl

scientific article published on 12 September 2006

Modulation of the activity of dopaminergic neurons by SK channels: a potential target for the treatment of Parkinson's disease?

scientific article

Mortality from Parkinson's disease in China: Findings from a five-year follow up study in Shanghai

scientific article published on July 2015

Motor-symptom laterality affects acquisition in Parkinson's disease: A cognitive and functional magnetic resonance imaging study

scientific article published on 08 May 2017

Mutation Screening of the CHCHD2 Gene for Alzheimer's Disease and Frontotemporal Dementia in Chinese Mainland Population

scientific article published in January 2018

Mutation analysis of CHCHD2 gene in Chinese Han familial essential tremor patients and familial Parkinson's disease patients

scientific article published on 11 October 2016

Myotonia congenita: novel mutations in CLCN1 gene

scientific article published on 11 August 2015

N1 and P1 Components Associate With Visuospatial-Executive and Language Functions in Normosmic Parkinson's Disease: An Event-Related Potential Study

scholarly article by Yi-Qi Lin et al published 2019 in Frontiers in Aging Neuroscience

Neuroprotection by pergolide against levodopa-induced cytotoxicity of neural stem cells

scientific article published in December 2004

Neuroprotection of Parkin against apoptosis is independent of inclusion body formation

scientific article published in July 2005

Neuroprotective effects of PACAP27 in mice model of Parkinson's disease involved in the modulation of K(ATP) subunits and D2 receptors in the striatum

scientific article published on 28 April 2008

New protein kinase C activator regulates amyloid precursor protein processing in vitro by increasing alpha-secretase activity

scientific article

Non-motor symptoms in Chinese Parkinson's disease patients with and without LRRK2 G2385R and R1628P variants.

scientific article

Non-motor symptoms of Parkinson’s disease in China: A review of the literature

scientific article published on March 17, 2012

Novel ATM mutations with ataxia-telangiectasia.

scientific article

Novel Mutations in Endoplasmic Reticulum Lipid Raft-associated Protein 2 Gene Cause Pure Hereditary Spastic Paraplegia Type 18

scientific article published on January 2016

Novel SPG11 mutations in Chinese families with hereditary spastic paraplegia with thin corpus callosum

scientific article

Overexpression of Kir2.3 in PC12 cells resists rotenone-induced neurotoxicity associated with PKC signaling pathway

scientific article published on 11 July 2008

P2Y6 receptor and immunoinflammation

scientific article published on June 2009

PACAP protects neuronal differentiated PC12 cells against the neurotoxicity induced by a mitochondrial complex I inhibitor, rotenone

scientific article published in July 2005

PMS777, a new cholinesterase inhibitor with anti-platelet activated factor activity, regulates amyloid precursor protein processing in vitro

scientific article

PPARgamma agonist curcumin reduces the amyloid-beta-stimulated inflammatory responses in primary astrocytes

scientific article published in January 2010

PRRT2 truncated mutations lead to nonsense-mediated mRNA decay in Paroxysmal Kinesigenic Dyskinesia

scientific article

Parkinson disease with REM sleep behavior disorder: features, α-synuclein, and inflammation

scientific article published on 6 February 2015

Parkinson disease with constipation: clinical features and relevant factors

scientific article published on 12 January 2018

Paroxysmal kinesigenic dyskinesia: Clinical and genetic analyses of 110 patients.

scientific article published on 7 October 2015

Penetrance of LRRK2 G2385R and R1628P is modified by common PD-associated genetic variants

scientific article published on 2 June 2012

Peripheral Blood MicroRNA Expression Profiles in Alzheimer's Disease: Screening, Validation, Association with Clinical Phenotype and Implications for Molecular Mechanism.

scientific article

Phenotype of postural instability/gait difficulty in Parkinson disease: relevance to cognitive impairment and mechanism relating pathological proteins and neurotransmitters

scientific article published on 23 March 2017

Phosphoproteome study reveals Hsp27 as a novel signaling molecule involved in GDNF-induced neurite outgrowth

scientific article published on June 2009

Plasma epidermal growth factor decreased in the early stage of Parkinson's disease

scientific article published on June 2015

Plasma metabolite profiles of Alzheimer's disease and mild cognitive impairment.

scientific article

Potential Similarities in Temporal Lobe Epilepsy and Alzheimer’s Disease: From Clinic to Pathology

scientific article

Prevalence and Risk Factor of Cognitive Impairment were Different between Urban and Rural Population: A Community-Based Study

scientific article published on 27 October 2015

Prevalence and clinical features of non-motor symptoms of essential tremor in Shanghai rural area

scientific article published on 4 November 2015

Prevalence and risk factors for depression and anxiety in Chinese patients with Parkinson disease

scientific article published on 22 November 2017

Prevalence of wearing-off and dyskinesia among the patients with Parkinson's disease on levodopa therapy: a multi-center registry survey in mainland China

scientific article

Progressive myoclonus epilepsy without renal failure in a Chinese family with a novel mutation in SCARB2 gene and literature review

scientific article published on 14 March 2018

Proline-rich transmembrane protein 2-negative paroxysmal kinesigenic dyskinesia: Clinical and genetic analyses of 163 patients

scientific article

Proteasome inhibitor lactacystin induces cholinergic degeneration

scientific article

Protective effects of erythropoietin on tau phosphorylation induced by beta-amyloid

scientific article

RBD: a red flag for cognitive impairment in Parkinson's disease?

scientific article published on 31 January 2018

REM sleep behavior disorder was associated with Parkinson's disease: a community-based study

scientific article

ROCK1 Is Associated with Alzheimer's Disease-Specific Plaques, as well as Enhances Autophagosome Formation But not Autophagic Aβ Clearance

scientific article

Repeated lipopolysaccharide stimulation induces cellular senescence in BV2 cells

scientific article published on 11 January 2012

Restless legs syndrome in Chinese elderly people of an urban suburb in Shanghai: A community-based survey

scientific article published on December 6, 2011

Restless legs syndrome in Parkinson disease: Clinical characteristics, abnormal iron metabolism and altered neurotransmitters

scientific article

Retraction: Dopaminergic regeneration by neurturin-overexpressing c17.2 neural stem cells in a rat model of Parkinson's disease

scientific article published on 4 November 2009

Retrieval Deficiency in Brain Activity of Working Memory in Amnesic Mild Cognitive Impairment Patients: A Brain Event-Related Potentials Study

scientific article published on 23 March 2016

Risk factors for cognitive decline in elderly people: findings from the two-year follow-up study in a Shanghai urban community

scientific article published on January 2014

SNCA Gene, but Not MAPT, Influences Onset Age of Parkinson's Disease in Chinese and Australians

scientific article published on 15 April 2015

Salidroside attenuates hypoxia-induced abnormal processing of amyloid precursor protein by decreasing BACE1 expression in SH-SY5Y cells

scientific article published on 3 July 2010

Salivary DJ-1 could be an indicator of Parkinson's disease progression

scientific article

Serotonergic dysfunctions and abnormal iron metabolism: Relevant to mental fatigue of Parkinson disease

scientific article

Serum level of interleukin-6 in Chinese patients with multiple sclerosis.

scientific article published on 25 May 2012

Serum levels of interleukin (IL)-18, IL-23 and IL-17 in Chinese patients with multiple sclerosis

scientific article published on January 9, 2012

Sleep disorders in Chinese patients with Parkinson's disease: validation study of a Chinese version of Parkinson's disease sleep scale

scientific article published on 27 May 2008

Small peptide inhibitor of JNK3 protects dopaminergic neurons from MPTP induced injury via inhibiting the ASK1-JNK3 signaling pathway

scientific article published on 9 April 2015

Starvation triggers Abeta42 generation from human umbilical vascular endothelial cells

scientific article published in June 2010

Substantia nigra echogenicity correlated with clinical features of Parkinson's disease

scientific article published on 26 January 2016

TMEM230 stop codon mutation is rare in parkinson's disease and essential tremor in eastern China

scientific article published on 21 November 2016

Testosterone, Estradiol, and Sex Hormone-Binding Globulin in Alzheimer's Disease: A Meta-Analysis

scientific article published on 18 December 2015

The Gab2 in signal transduction and its potential role in the pathogenesis of Alzheimer's disease

scientific article

The MTHFD1L gene rs11754661 marker is associated with susceptibility to Alzheimer's disease in the Chinese Han population

scientific article published on July 8, 2011

The association between Parkinson's disease and melanoma: a systematic review and meta-analysis

scientific article

The association between two single nucleotide polymorphisms within the insulin-degrading enzyme gene and Alzheimer’s disease in a Chinese Han population

scientific article published on May 1, 2012

The association of weight status with cognitive impairment in the elderly population of a Shanghai suburb

scientific article published in January 2013

The changing phenotype of microglia from homeostasis to disease

scientific article

The iPS technique provides hope for Parkinson's disease treatment

scientific article published on September 2010

The impact of human-computer interaction-based comprehensive training on the cognitive functions of cognitive impairment elderly individuals in a nursing home

scientific article published in January 2013

The potential role of microRNA-146 in Alzheimer’s disease: Biomarker or therapeutic target?

scientific article published on December 29, 2011

The prevalence of CD33 and MS4A6A variant in Chinese Han population with Alzheimer’s disease

scientific article published on March 1, 2012

The role of DJ-1 in the pathogenesis of Parkinson's disease.

scientific article published on July 2006

The role of cognitive activity in cognition protection: from Bedside to Bench

scientific article published on 28 March 2017

The role of substantia nigra sonography in the differentiation of Parkinson's disease and multiple system atrophy

scholarly article by Hai-Yan Zhou et al published 2018 in Translational Neurodegeneration

The role of synphilin-1 in the pathogenesis of Parkinson's disease

scientific article published on July 2006

Tics as an initial manifestation of juvenile Huntington's disease: case report and literature review

scientific article published on 8 August 2017

Traditional Chinese medicine: a promising candidate for the treatment of Alzheimer's disease

scientific article published on 28 February 2013

Transcranial sonography of the substantia nigra and its correlation with DAT-SPECT in the diagnosis of Parkinson's disease

scientific article published on 3 June 2015

Transplantation of bone marrow stromal cells containing the neurturin gene in rat model of Parkinson's disease

scientific article published on 24 December 2006

Transthyretin-related hereditary amyloidosis in a Chinese family with TTR Y114C mutation.

scientific article

Treatment of Parkinson's Disease by Genetically Modified Immortalized Fibroblasts

scientific article

Using gastrocnemius sEMG and plasma α-synuclein for the prediction of freezing of gait in Parkinson's disease patients

scientific article

Vacuolar protein sorting 35 Asp620Asn mutation is rare in the ethnic Chinese population with Parkinson's disease

scientific article published on March 10, 2012

Validation of the Chinese version of Addenbrooke's cognitive examination-revised for screening mild Alzheimer's disease and mild cognitive impairment

scientific article published on 2 November 2013

Visual hallucinations and associated factors in Chinese patients with Parkinson’s disease: Roles of RBD and visual pathway deficit

scientific article published on September 15, 2010