List of works by Jeffrey H Kordower

A confocal microscopic analysis of galaninergic hyperinnervation of cholinergic basal forebrain neurons in Alzheimer's disease

scientific article published on April 1997

A double-blind controlled trial of bilateral fetal nigral transplantation in Parkinson's disease

scientific article published in September 2003

A phase 1 clinical trial of nerve growth factor gene therapy for Alzheimer disease

scientific article

A phase1 study of stereotactic gene delivery of AAV2-NGF for Alzheimer's disease

scientific article published on 7 January 2014

AAV2-Neurturin for Parkinson's Disease: What Lessons Have We Learned?

scientific article published on January 2016

AAV2-mediated delivery of human neurturin to the rat nigrostriatal system: long-term efficacy and tolerability of CERE-120 for Parkinson's disease

scientific article

Abnormal alpha-synuclein reduces nigral voltage-dependent anion channel 1 in sporadic and experimental Parkinson's disease

scientific article

Adrenal chromaffin cells as transplants in animal models of Parkinson's disease

scientific article published on August 1989

Adrenal medullary autografts into the basal ganglia of Cebus monkeys: graft viability and fine structure

scientific article

Adrenal medullary autografts into the basal ganglia of Cebus monkeys: injury-induced regeneration.

scientific article published on October 1988

Adrenal medullary tissue grafting in Parkinson's disease

scientific article published on 01 July 1988

Age and region-specific responses of microglia, but not astrocytes, suggest a role in selective vulnerability of dopamine neurons after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure in monkeys

scientific article

Age-Related Vulnerability of Developing Cholinergic Basal Forebrain Neurons Following Excitotoxic Lesions of the Hippocampus ⬇️

scientific article published on August 1, 1994

Age-associated increases of alpha-synuclein in monkeys and humans are associated with nigrostriatal dopamine depletion: Is this the target for Parkinson's disease?

scientific article published on 18 October 2006

Age-related accumulation of Marinesco bodies and lipofuscin in rhesus monkey midbrain dopamine neurons: relevance to selective neuronal vulnerability

scientific article published in June 2007

Age-related alterations in GABA(A) receptor subunits in the nonhuman primate hippocampus

scientific article published on 20 January 2006

Age-related changes in dopamine transporters and accumulation of 3-nitrotyrosine in rhesus monkey midbrain dopamine neurons: relevance in selective neuronal vulnerability to degeneration

scientific article

Age-related changes in glial cells of dopamine midbrain subregions in rhesus monkeys

scientific article

Age-related declines in nigral neuronal function correlate with motor impairments in rhesus monkeys

scientific article published in November 1998

Age-related decreases in GTP-cyclohydrolase-I immunoreactive neurons in the monkey and human substantia nigra

scientific article published on 01 October 2000

Age-related decreases in Nurr1 immunoreactivity in the human substantia nigra

scientific article

Ageing as a primary risk factor for Parkinson's disease: evidence from studies of non-human primates

scientific article

Aging and Parkinson's disease: Different sides of the same coin?

scientific article

Aging-related changes in the nigrostriatal dopamine system and the response to MPTP in nonhuman primates: diminished compensatory mechanisms as a prelude to parkinsonism

scientific article published on 23 January 2007

Alpha-synuclein in colonic submucosa in early untreated Parkinson's disease

scientific article published on 15 July 2011

Alpha-synuclein propagation: New insights from animal models

scientific article published on 08 September 2015

Alterations in Activity-Dependent Neuroprotective Protein in Sporadic and Experimental Parkinson's Disease

scientific article

Alterations in axonal transport motor proteins in sporadic and experimental Parkinson's disease

scientific article

Alterations in lysosomal and proteasomal markers in Parkinson's disease: relationship to alpha-synuclein inclusions

scientific article

An in vivo and in vitro assessment of differentiated neuroblastoma cells as a source of donor tissue for transplantation

scientific article published in January 1987

Analysis of YFP(J16)-R6/2 reporter mice and postmortem brains reveals early pathology and increased vulnerability of callosal axons in Huntington's disease

scientific article

Analysis of age-related changes in psychosine metabolism in the human brain.

scientific article published on 26 February 2018

Animal models of Huntington's disease

scientific article

Animal models of age- and disease-related cognitive decline: perspectives on the models and therapeutic strategies

scientific article published on September 1988

Animal rights terrorists: what every neuroscientist should know

scientific article published in September 2009

Apolipoprotein E-immunoreactivity in aged rhesus monkey cortex: colocalization with amyloid plaques

scientific article published on 01 September 1994

Are growth factors the answer?

scientific article published on December 2009

Ascending cholinergic pathways: functional organization and implications for disease models

scientific article published on January 1993

Atrophy of cholinergic basal forebrain neurons following excitotoxic cortical lesions is reversed by intravenous administration of an NGF conjugate

scientific article

B2 bradykinin receptor immunoreactivity in rat brain

scientific article

Basal ganglia lesions after MPTP administration in rhesus monkeys

scientific article published on August 2006

Behavioral and morphological comparison of two nonhuman primate models of Huntington's disease

scientific article published in January 2002

Bilateral fetal nigral transplantation into the postcommissural putamen in Parkinson's disease.

scientific article published in September 1995

Bioactivity of AAV2-neurturin gene therapy (CERE-120): differences between Parkinson's disease and nonhuman primate brains.

scientific article published on 18 November 2010

Broad distribution of ataxin 1 silencing in rhesus cerebella for spinocerebellar ataxia type 1 therapy

scientific article

Can intrabodies serve as neuroprotective therapies for Parkinson's disease? Beginning thoughts

scientific article published on January 2013

Celebrating neural repair

scientific article published in July 2009

Cell therapy for Parkinson's disease: what next?

scientific article published on January 2013

Cell transplantation and gene therapy in Parkinson's disease

scientific article

Cellular Delivery of NGF Does Not Alter the Expression of β-Amyloid Immunoreactivity in Young or Aged Nonhuman Primates ⬇️

scientific article published on June 1, 1997

Cellular delivery of CNTF but not NT-4/5 prevents degeneration of striatal neurons in a rodent model of Huntington's disease

scientific article published on March 1998

Cellular delivery of trophic factors for the treatment of Huntington's disease: is neuroprotection possible?

scientific article

Cellular delivery of trophic factors for the treatment of Huntington's disease: is neuroprotection possible?

scientific article published on 01 January 2000

Chronic ischemic stroke model in cynomolgus monkeys: behavioral, neuroimaging and anatomical study

scientific article

Chronic stress-induced gut dysfunction exacerbates Parkinson's disease phenotype and pathology in a rotenone-induced mouse model of Parkinson's disease

scientific article published on 21 December 2018

Circuit-specific alterations of N-methyl-D-aspartate receptor subunit 1 in the dentate gyrus of aged monkeys

scientific article

Clinical pattern and risk factors for dyskinesias following fetal nigral transplantation in Parkinson's disease: a double blind video-based analysis

scientific article published in February 2009

Clinicopathological findings following intraventricular glial-derived neurotrophic factor treatment in a patient with Parkinson's disease

scientific article published on September 1999

Cografts of adrenal medulla with C6 glioma cells in rats with 6-hydroxydopamine-induced lesions.

scientific article published in January 1990

Connections of the hippocampal formation in humans: II. The endfolial fiber pathway ⬇️

scientific article published on September 1, 1997

Continuous DOPA synthesis from a single AAV: dosing and efficacy in models of Parkinson's disease

scientific article published on January 2013

Corrigendum to: In Utero Exposure to Anesthetics Alters Neuronal Migration Pattern in Developing Cerebral Cortex and Causes Postnatal Behavioral Deficits in Rats

scientific article published on 22 June 2020

Cortical ablation induces a spreading calcium-dependent, secondary pathogenesis which can be reduced by inhibiting calpain

scientific article published in February 1999

Cryopreservation Maintains Functionality of Human iPSC Dopamine Neurons and Rescues Parkinsonian Phenotypes In Vivo.

scientific article published on 22 May 2017

Cyclosporin A protects striatal neurons in vitro and in vivo from 3-nitropropionic acid toxicity.

scientific article published in October 2000

Decreased alpha-synuclein expression in the aging mouse substantia nigra

scientific article published in October 2009

Decreased trkA gene expression within basal forebrain neurons in Alzheimer's disease.

scientific article published on December 1996

Deep brain stimulation for treatment of obesity in rats

scientific article published on 01 October 2007

Delayed onset of progressive dystonia following subacute 3-nitropropionic acid treatment in Cebus apella monkeys

scientific article published on May 2000

Delivery of neurotrophic factors to the CNS using encapsulated cells: developing treatments for neurodegenerative diseases.

scientific article published on January 1995

Delivery of neurturin by AAV2 (CERE-120)-mediated gene transfer provides structural and functional neuroprotection and neurorestoration in MPTP-treated monkeys

scientific article published in December 2006

Delivery of therapeutic molecules into the CNS.

scientific article

Delivery of trophic factors to the primate brain

scientific article

Demonstration of prion-like properties of mutant huntingtin fibrils in both in vitro and in vivo paradigms

scientific article published on 20 February 2019

Detecting Alpha Synuclein Seeding Activity in Formaldehyde-Fixed MSA Patient Tissue by PMCA.

scientific article

Differential transduction following basal ganglia administration of distinct pseudotyped AAV capsid serotypes in nonhuman primates

scientific article

Differential vulnerability of neurons in Huntington's disease: the role of cell type-specific features

scientific article

Disease Modification Through Trophic Factor Delivery

scientific article published on 01 January 2018

Disease duration and the integrity of the nigrostriatal system in Parkinson's disease

scientific article published on August 2013

Disease modification and biomarker development in Parkinson disease: Revision or reconstruction?

scientific article published on 26 February 2020

Dissociation of galaninergic and neurotrophic plasticity in Down syndrome and Alzheimer disease

scientific article published on 01 January 1995

Dissociation of p75 receptors and nerve growth factor neurotrophic effects: lack of p75 immunoreactivity in striatum following physical trauma, excitotoxicity and NGF administration

scientific article published on 01 January 1996

Distribution of high affinity choline transporter immunoreactivity in the primate central nervous system

scientific article

Do subjects with minimal motor features have prodromal PD?

scientific article published on 8 February 2018

Does Developmental Variability in the Number of Midbrain Dopamine Neurons Affect Individual Risk for Sporadic Parkinson's Disease?

scientific article published on 01 January 2020

Dopamine D2 receptor mRNA is expressed in maturing neurons of the human hippocampal and subicular fields

scientific article published in November 1997

Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's disease

scientific article (publication date: 6 November 2011)

Dopamine transporter-immunoreactive neurons decrease with age in the human substantia nigra

scientific article

Dopaminergic transplantation for Parkinson's disease: current status and future prospects

scientific article

Dopaminergic transplants in patients with Parkinson's disease: neuroanatomical correlates of clinical recovery

scientific article published on March 1997

Doublecortin expression in adult cat and primate cerebral cortex relates to immature neurons that develop into GABAergic subgroups

scientific article

Doublecortin-expressing cells persist in the associative cerebral cortex and amygdala in aged nonhuman primates

scientific article published on 13 October 2009

Down-regulation of trkA mRNA within nucleus basalis neurons in individuals with mild cognitive impairment and Alzheimer's disease

scientific article

Early changes in Huntington's disease patient brains involve alterations in cytoskeletal and synaptic elements

scientific article

Early degenerative changes in transgenic mice expressing mutant huntingtin involve dendritic abnormalities but no impairment of mitochondrial energy production

scientific article

Effect of stereotaxic intrastriatal cografts of autologous adrenal medulla and peripheral nerve in Parkinson's disease: two-year follow-up study

scientific article published in October 1997

Effects of estrogen replacement therapy on cholinergic basal forebrain neurons and cortical cholinergic innervation in young and aged ovariectomized rhesus monkeys

scientific article published on April 2004

Encapsulated PC12 cell transplants into hemiparkinsonian monkeys: a behavioral, neuroanatomical, and neurochemical analysis

scientific article published on March 1995

Endocytic vesicle rupture is a conserved mechanism of cellular invasion by amyloid proteins

scientific article published on 19 May 2017

Endogenous alpha-synuclein monomers, oligomers and resulting pathology: let's talk about the lipids in the room

scientific article published on 12 November 2019

Enduring cortical alterations after a single in-vivo treatment of HIV-1 Tat.

scientific article published on October 2012

Entorhinal cortex beta-amyloid load in individuals with mild cognitive impairment

scientific article

Estrogen increases the number of spinophilin-immunoreactive spines in the hippocampus of young and aged female rhesus monkeys

scientific article published in October 2003

Estrogen receptor alpha containing neurons in the monkey forebrain: lack of association with calcium binding proteins and choline acetyltransferase

scientific article

Estrogen receptor immunoreactivity within subregions of the rat forebrain: neuronal distribution and association with perikarya containing choline acetyltransferase

scientific article published on December 1999

Estrogen replacement increases spinophilin-immunoreactive spine number in the prefrontal cortex of female rhesus monkeys

scientific article

Etiology of Parkinson's disease: Genetics and environment revisited

scientific article

Evaluation of alpha-synuclein immunohistochemical methods for the detection of Lewy-type synucleinopathy in gastrointestinal biopsies

scientific article published on 4 April 2016

Evidence that Cereport's ability to increase permeability of rat gliomas is dependent upon extent of tumor growth: implications for treating newly emerging tumor colonies

scientific article

Excitotoxic and metabolic damage to the rodent striatum: role of the P75 neurotrophin receptor and glial progenitors

scientific article published in March 2002

Expression, bioactivity, and safety 1 year after adeno-associated viral vector type 2-mediated delivery of neurturin to the monkey nigrostriatal system support cere-120 for Parkinson's disease

scientific article published on April 2009

Extensive neuroprotection by choroid plexus transplants in excitotoxin lesioned monkeys

scientific article published on 14 June 2006

Failure of proteasome inhibitor administration to provide a model of Parkinson's disease in rats and monkeys

scientific article published in August 2006

Fetal grafting for Parkinson's disease: expression of immune markers in two patients with functional fetal nigral implants

scientific article published in May 1997

Fetal grafts for Parkinson's disease: Decades in the making

scientific article published on 31 May 2016

Fetal nigral grafts survive and mediate clinical benefit in a patient with Parkinson's disease

scientific article published on May 1998

Fetal nigral transplantation as a therapy for Parkinson's disease

scientific article published on March 1996

Focal not widespread grafts induce novel dyskinetic behavior in parkinsonian rats

scientific article published on 10 August 2005

Functional fetal nigral grafts in a patient with Parkinson's disease: chemoanatomic, ultrastructural, and metabolic studies

scientific article published on 01 June 1996

Future of cell and gene therapies for Parkinson's disease

scientific article published on December 2008

GDNF and Parkinson's Disease: Where Next? A Summary from a Recent Workshop

scientific article published on 03 June 2020

GDNF family ligands: a potential future for Parkinson's disease therapy

scientific article published on September 2011

GFAP knockout mice have increased levels of GDNF that protect striatal neurons from metabolic and excitotoxic insults ⬇️

scientific article published on June 30, 2003

Galanin expression within the basal forebrain in Alzheimer's disease. Comments on therapeutic potential

scientific article

Galanin immunoreactivity in the primate central nervous system

scientific article published on May 22, 1992

Galanin immunoreactivity within the primate basal forebrain: evolutionary change between monkeys and apes.

scientific article published in October 1993

Galanin-like immunoreactivity within the primate basal forebrain: differential staining patterns between humans and monkeys

scientific article

Galaninergic innervation of the cholinergic vertical limb of the diagonal band (Ch2) and bed nucleus of the stria terminalis in aging, Alzheimer's disease and Down's syndrome.

scientific article published on September 1993

Gene delivery of AAV2-neurturin for Parkinson's disease: a double-blind, randomised, controlled trial

scientific article

Gene delivery of neurturin to putamen and substantia nigra in Parkinson disease: A double-blind, randomized, controlled trial

scientific article published on 10 June 2015

Gene therapy approaches for the treatment of Parkinson's disease

scientific article

Gene therapy for Huntington's disease

scientific article published on 24 December 2011

Gene therapy for Parkinson's disease

scientific article published on 01 January 2010

Gene therapy for Parkinson's disease: still a hot topic?

scientific article

Gene therapy to the rescue in Parkinson's disease. Response from Kordower and Aebischer

scientific article published in March 2001

Gene transfer of trophic factors and stem cell grafting as treatments for Parkinson's disease

scientific article published in May 2006

Gene transfer provides a practical means for safe, long-term, targeted delivery of biologically active neurotrophic factor proteins for neurodegenerative diseases

scientific article published on October 2011

Generation and transplantation of EGF-responsive neural stem cells derived from GFAP-hNGF transgenic mice.

scientific article published on November 1997

Grafts of EGF-responsive neural stem cells derived from GFAP-hNGF transgenic mice: trophic and tropic effects in a rodent model of Huntington's disease.

scientific article published on October 1997

How strong is the evidence that Parkinson's disease is a prion disorder?

scientific article published on June 2016

Human neural progenitors deliver glial cell line-derived neurotrophic factor to parkinsonian rodents and aged primates

scientific article published on March 2006

Human neural stem cell transplants improve motor function in a rat model of Huntington's disease

scientific article published on July 2004

Huntington's disease: pathological mechanisms and therapeutic strategies

scientific article published on January 2007

Immunotherapy in Parkinson's disease: Current status and future directions

scientific article published on 25 August 2019

Implants of encapsulated human CNTF-producing fibroblasts prevent behavioral deficits and striatal degeneration in a rodent model of Huntington's disease

scientific article published on August 1996

Implants of polymer-encapsulated human NGF-secreting cells in the nonhuman primate: rescue and sprouting of degenerating cholinergic basal forebrain neurons

scientific article published on November 1994

In memorium: Roy A.E. Bakay, MD.

scientific article

In utero Exposure to Anesthetics Alters Neuronal Migration Pattern in Developing Cerebral Cortex and Causes Postnatal Behavioral Deficits in Rats

scientific article published on 11 April 2019

In vivo evaluation of [(123)I]MNI-420: a novel single photon emission computed tomography radiotracer for imaging of adenosine 2A receptors in brain

scientific article published on 16 January 2013

In vivo gene delivery of glial cell line--derived neurotrophic factor for Parkinson's disease

scientific article

Increased intestinal permeability correlates with sigmoid mucosa alpha-synuclein staining and endotoxin exposure markers in early Parkinson's disease

scientific article

Induction of alpha-synuclein pathology in the enteric nervous system of the rat and non-human primate results in gastrointestinal dysmotility and transient CNS pathology

scientific article published on 13 January 2018

Inflammation in Experimental Models of α-Synucleinopathies

scientific article published on 03 October 2020

Influence of Donor Age on the Survival of Human Embryonic Dopaminergic Neural Grafts

scientific article published in October 1992

Influence of cell preparation and target location on the behavioral recovery after striatal transplantation of fetal dopaminergic neurons in a primate model of Parkinson's disease

scientific article

Inhibitors of cyclooxygenase-2, but not cyclooxygenase-1 provide structural and functional protection against quinolinic acid-induced neurodegeneration

scientific article published on 3 April 2003

Injectable hydrogels providing sustained delivery of vascular endothelial growth factor are neuroprotective in a rat model of Huntington's disease

scientific article published on 9 July 2009

Intrastriatal CERE-120 (AAV-Neurturin) protects striatal and cortical neurons and delays motor deficits in a transgenic mouse model of Huntington's disease

scientific article published on 25 December 2008

Intrastriatal Infusions of Brain-Derived Neurotrophic Factor: Retrograde Transport and Colocalization with Dopamine Containing Substantia Nigra Neurons in Rat ⬇️

scientific article published on 01 September 1994

Intrastriatal alpha-synuclein fibrils in monkeys: spreading, imaging and neuropathological changes

scientific article published on 01 November 2019

Intrastriatal and intraventricular infusion of brain-derived neurotrophic factor in the cynomologous monkey: distribution, retrograde transport and co-localization with substantia nigra dopamine-containing neurons

scientific article published in March 1996

Intrastriatal implants of polymer encapsulated cells genetically modified to secrete human nerve growth factor: trophic effects upon cholinergic and noncholinergic striatal neurons

scientific article published on May 1996

Intravenous administration of a transferrin receptor antibody-nerve growth factor conjugate prevents the degeneration of cholinergic striatal neurons in a model of Huntington disease

scientific article published on September 1994

Introduction: gene therapy has gone from a pipe dream to clinical reality

scientific article

Is Axonal Degeneration a Key Early Event in Parkinson's Disease?

scientific article

Is alpha-synuclein in the colon a biomarker for premotor Parkinson's disease? Evidence from 3 cases

scientific article published on 01 May 2012

Issues regarding gene therapy products for Parkinson's disease: the development of CERE-120 (AAV-NTN) as one reference point

scientific article published on January 2007

Kinetic modeling and occupancy measures of the norepinephrine transporters in baboons using single photon emission computed tomography with (123)I-INER.

scientific article published on 31 October 2012

Knockout of p75NTR does not alter the viability of striatal neurons following a metabolic or excitotoxic injury

scientific article

Lentiviral gene transfer to the nonhuman primate brain

scientific article

Lentivirally delivered glial cell line-derived neurotrophic factor increases the number of striatal dopaminergic neurons in primate models of nigrostriatal degeneration.

scientific article published on June 2002

Lewy body pathology in fetal grafts

scientific article published on January 2010

Lewy body pathology in long-term fetal nigral transplants: is Parkinson's disease transmitted from one neural system to another?

scientific article published on 01 January 2009

Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease

scientific article

Long-term evaluation of bilateral fetal nigral transplantation in Parkinson disease

scientific article published on February 1999

Long-term gonadal hormone treatment and endogenous neurogenesis in the dentate gyrus of the adult female monkey

scientific article

Long-term post-mortem studies following neurturin gene therapy in patients with advanced Parkinson's disease

scientific article published on 01 March 2020

Loss and atrophy of layer II entorhinal cortex neurons in elderly people with mild cognitive impairment

scientific article published in February 2001

Loss of One Engrailed1 Allele Enhances Induced α-Synucleinopathy

scientific article published on 01 January 2019

Loss of basal forebrain P75(NTR) immunoreactivity in subjects with mild cognitive impairment and Alzheimer's disease

scientific article published in February 2002

Loss of developing cholinergic basal forebrain neurons following excitotoxic lesions of the hippocampus: rescue by neurotrophins

scientific article published on December 1994

Loss of nerve growth factor receptor-containing neurons in Alzheimer's disease: a quantitative analysis across subregions of the basal forebrain

scientific article

Loss of nucleus basalis neurons containing trkA immunoreactivity in individuals with mild cognitive impairment and early Alzheimer's disease

scientific article

Mechanisms for cell-to-cell propagation no longer lag behind

scientific article published on 22 November 2016

Misfolded proteins in Huntington disease fetal grafts: further evidence of cell-to-cell transfer?

scientific article published on 9 July 2014

Missing pieces in the Parkinson's disease puzzle

scientific article

Mitochondrial pyruvate carrier regulates autophagy, inflammation, and neurodegeneration in experimental models of Parkinson's disease

scientific article published in December 2016

Mitomycin-C treatment during differentiation of induced pluripotent stem cell-derived dopamine neurons reduces proliferation without compromising survival or function in vivo

scientific article published on 30 September 2020

Modeling Parkinson's disease

scientific article published on 01 October 2009

Multicenter Assessment of Immunohistochemical Methods for Pathological Alpha-Synuclein in Sigmoid Colon of Autopsied Parkinson's Disease and Control Subjects

scientific article published on 31 August 2016

NGF and Alzheimer's disease: unfulfilled promise and untapped potential

scientific article

NGF receptor (p75)-immunoreactivity in the developing primate basal ganglia

scientific article

NGF-like trophic support from peripheral nerve for grafted rhesus adrenal chromaffin cells

scientific article published in September 1990

Neonatal immune-tolerance in mice does not prevent xenograft rejection

scientific article published on 16 January 2014

Nerve growth factor in Alzheimerʼs disease: defective retrograde transport to nucleus basalis ⬇️

scientific article published on May 9, 1995

Nerve growth factor receptor and choline acetyltransferase remain colocalized in the nucleus basalis (Ch4) of Alzheimer's patients

scientific article

Nerve growth factor receptor expressing human basal forebrain neurons: pathologic alterations in Alzheimer's and Parkinson's disease

scientific article

Nerve growth factor receptor immunoreactive profiles in the normal, aged human basal forebrain: colocalization with cholinergic neurons

scientific article

Nerve growth factor receptor immunoreactivity in the new world monkey (Cebus apella) and human cerebellum

scientific article published in June 1991

Nerve growth factor receptor immunoreactivity in the nonhuman primate (Cebus apella): distribution, morphology, and colocalization with cholinergic enzymes

scientific article

Nerve growth factor receptor-immunoreactive neurons within the developing human cortex

scientific article published on September 1992

Nerve growth factor-like immunoreactive profiles in the primate basal forebrain and hippocampal formation

scientific article

Neural repair strategies for Parkinson's disease: insights from primate models

scientific article

Neural transplantation as a therapy for Parkinson's disease

scientific article published on January 1997

Neural transplants in patients with Huntington's disease undergo disease-like neuronal degeneration

scientific article published on 20 July 2009

Neuroblastoma cells in neural transplants: a neuroanatomical and behavioral analysis

scientific article published in August 1987

Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease

scientific article

Neuropathological evidence of graft survival and striatal reinnervation after the transplantation of fetal mesencephalic tissue in a patient with Parkinson's disease

scientific article published on April 1995

Neuropathological study 16 years after autologous adrenal medullary transplantation in a Parkinson's disease patient

scientific article

Neuropathology in transplants in Parkinson's disease: implications for disease pathogenesis and the future of cell therapy

scientific article published on January 2012

Neuropathology of fetal nigra transplants for Parkinson's disease

scientific article

Neuropathology of fetal nigral grafts in patients with Parkinson's disease.

scientific article published in January 1998

Neuroprotection for Parkinson's disease using viral vector-mediated delivery of GDNF.

scientific article

Neurotrophic factor therapy for Parkinson’s disease

scientific article published on January 1, 2010

Neurturin gene therapy improves motor function and prevents death of striatal neurons in a 3-nitropropionic acid rat model of Huntington's disease

scientific article

Neutralization of RANTES and Eotaxin Prevents the Loss of Dopaminergic Neurons in a Mouse Model of Parkinson Disease

scientific article published on 12 May 2016

Novel oligodendroglial alpha synuclein viral vector models of multiple system atrophy: studies in rodents and nonhuman primates

scientific article

Nurr1 in Parkinson's disease and related disorders

scientific article published on January 2006

Ontogeny of the dopamine D2 receptor mRNA expressing cells in the human hippocampal formation and temporal neocortex

scientific article

Optimizing maturity and dose of iPSC-derived dopamine progenitor cell therapy for Parkinson's disease

scientific article published on 21 April 2022

PGC-1α Promoter Methylation in Parkinson's Disease

scientific article published on 28 August 2015

Parkinson's disease and prion disease: Straining the comparison

scientific article

Parkinsonian monkeys with prior levodopa-induced dyskinesias followed by fetal dopamine precursor grafts do not display graft-induced dyskinesias

scientific article published on 15 July 2016

Past, present, and future of Parkinson's disease: A special essay on the 200th Anniversary of the Shaking Palsy

scientific article published in September 2017

Peripheral alpha-synuclein and Parkinson's disease

scientific article published on 01 July 2014

Post-mortem assessment of the short and long-term effects of the trophic factor neurturin in patients with α-synucleinopathies

scientific article published on 2 April 2015

Postmortem study of deep brain stimulation of the anterior thalamus: case report

scientific article

Prenatal 3,4-methylenedioxymethamphetamine (ecstasy) alters exploratory behavior, reduces monoamine metabolism, and increases forebrain tyrosine hydroxylase fiber density of juvenile rats

scientific article published in September 2003

Prenatal exposure to MDMA alters noradrenergic neurodevelopment in the rat.

scientific article published on 28 September 2011

Presence of tau pathology within foetal neural allografts in patients with Huntington's and Parkinson's disease

scientific article

Primate models of Parkinson's disease ⬇️

scientific article published on October 1, 2003

Probing the striatal dopamine system for a putative neuroprotective effect of deep brain stimulation in Parkinson's disease

scientific article published on 30 January 2018

Progression of intestinal permeability changes and alpha-synuclein expression in a mouse model of Parkinson's disease.

scientific article published on 4 November 2013

Propagation of host disease to grafted neurons: accumulating evidence

scientific article published on 26 September 2009

Properly scaled and targeted AAV2-NRTN (neurturin) to the substantia nigra is safe, effective and causes no weight loss: support for nigral targeting in Parkinson's disease

scientific article published on 17 June 2011

Proteasome inhibition and Parkinson's disease modeling

scientific article published on August 2006

Proteasome-targeted nanobodies alleviate pathology and functional decline in an α-synuclein-based Parkinson's disease model

scholarly article by Diptaman Chatterjee et al published 2018 in NPJ Parkinson's disease

Protective effect of encapsulated cells producing neurotrophic factor CNTF in a monkey model of Huntington's disease

scientific article published on March 1997

Putative chromaffin cell survival and enhanced host-derived TH-Fiber innervation following a functional adrenal medulla autograft for Parkinson's disease ⬇️

scientific article published on April 1, 1991

RET expression does not change with age in the substantia nigra pars compacta of rhesus monkeys

scientific article published on 13 June 2005

RNA amplification of bromodeoxyuridine labeled newborn neurons in the monkey hippocampus

scientific article published on 21 December 2004

Reduction in TrkA-immunoreactive neurons is not associated with an overexpression of galaninergic fibers within the nucleus basalis in Down's syndrome

scientific article published on March 2000

Reduction in p140-TrkA Receptor Protein within the Nucleus Basalis and Cortex in Alzheimer's Disease ⬇️

scientific article published on July 1, 1997

Regulatable promoters and gene therapy for Parkinson's disease: is the only thing to fear, fear itself?

scientific article published on 22 August 2007

Regulation of cyclic AMP response element binding and hippocampal plasticity-related genes by peroxisome proliferator-activated receptor α.

scientific article published on 22 August 2013

Reply to: “Being too inclusive about synuclein inclusions”

Response of the monkey cholinergic septohippocampal system to fornix transection: a histochemical and cytochemical analysis

scientific article published on August 1990

Robust graft survival and normalized dopaminergic innervation do not obligate recovery in a Parkinson disease patient

scientific article

Role of TLR4 in the gut-brain axis in Parkinson's disease: a translational study from men to mice

scientific article published on 15 December 2018

Role of heparin binding growth factors in nigrostriatal dopamine system development and Parkinson's disease

scientific article published on 22 February 2007

Selective inhibition of NF-kappaB activation prevents dopaminergic neuronal loss in a mouse model of Parkinson's disease

scholarly article

Special issue on stem cells

scientific article published on 01 August 2014

Spreading of alpha-synuclein - relevant or epiphenomenon?

scientific article published on 09 July 2019

Striatal Nurr1 Facilitates the Dyskinetic State and Exacerbates Levodopa-Induced Dyskinesia in a Rat Model of Parkinson's Disease

scientific article published on 27 March 2020

Striatal adrenal medulla/sural nerve cografts in hemiparkinsonian monkeys

scientific article published on January 1990

Striatal delivery of CERE-120, an AAV2 vector encoding human neurturin, enhances activity of the dopaminergic nigrostriatal system in aged monkeys

scientific article

Striatal trophic factor activity in aging monkeys with unilateral MPTP-induced parkinsonism.

scientific article

Structural and functional neuroprotection in a rat model of Huntington's disease by viral gene transfer of GDNF.

scientific article published on June 2003

Substantia nigra tangles are related to gait impairment in older persons

scientific article published in January 2006

Survival and early differentiation of human neural stem cells transplanted in a nonhuman primate model of stroke

scientific article published in July 2006

Systemic administration of the immunophilin ligand GPI 1046 in MPTP-treated monkeys

scientific article

T cell infiltration in both human multiple system atrophy and a novel mouse model of the disease

scientific article published on 29 January 2020

TDP-43 Proteinopathy: Aggregation and Propagation in the Pathogenesis of Amyotrophic Lateral Sclerosis

scientific article published on 23 May 2016

TRK and p75 neurotrophin receptor systems in the developing human brain

scientific article published on 01 June 1996

Targeting α-Synuclein as a therapy for Parkinson's disease: The battle begins.

scientific article

Telencephalic cholinergic system of the New World monkey (Cebus apella): morphological and cytoarchitectonic assessment and analysis of the projection to the amygdala

scientific article published on January 1989

Temporal evolution of microglia and α-synuclein accumulation following foetal grafting in Parkinson's disease

scientific article published on 01 June 2019

Testing NF-κB-based therapy in hemiparkinsonian monkeys

scientific article

The Potential Role of Gut-Derived Inflammation in Multiple System Atrophy.

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The Search for a Peripheral Biopsy Indicator of α-Synuclein Pathology for Parkinson Disease

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The aged monkey basal forebrain: rescue and sprouting of axotomized basal forebrain neurons after grafts of encapsulated cells secreting human nerve growth factor

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The first miracle in neurodegenerative disease: the discovery of oral levodopa

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The immunophilin ligand GPI-1046 does not have neuroregenerative effects in MPTP-treated monkeys

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The influence of donor age on the survival of solid and suspension intraparenchymal human embryonic nigral grafts.

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The native form of α-Synuclein: Monomer, tetramer, or a combination in equilibrium

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The prion hypothesis of Parkinson's disease

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The role of alpha-synuclein in Parkinson's disease: insights from animal models

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Therapeutic approaches to target alpha-synuclein pathology

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Transfer of host-derived α synuclein to grafted dopaminergic neurons in rat

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Transgene expression, bioactivity, and safety of CERE-120 (AAV2-neurturin) following delivery to the monkey striatum

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Transplanted dopaminergic neurons develop PD pathologic changes: a second case report

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Transplanted fetal striatum in Huntington's disease: phenotypic development and lack of pathology

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Treatment with fetal allografts

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TrkA-immunoreactive profiles in the central nervous system: colocalization with neurons containing p75 nerve growth factor receptor, choline acetyltransferase, and serotonin

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Trophic factor gene therapy for Parkinson's disease

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Trophic factors for Parkinson's disease: To live or let die.

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Trophic factors therapy in Parkinson's disease

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Tyrosine hydroxylase-immunoreactive somata within the primate subfornical organ: species specificity

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Upregulation of choline acetyltransferase activity in hippocampus and frontal cortex of elderly subjects with mild cognitive impairment.

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Viral delivery of glial cell line-derived neurotrophic factor improves behavior and protects striatal neurons in a mouse model of Huntington's disease

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Viral vector-mediated gene therapy for Parkinson's disease

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Viral-based rodent and nonhuman primate models of multiple system atrophy: Fidelity to the human disease

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Widespread Striatal Delivery of GDNF from Encapsulated Cells Prevents the Anatomical and Functional Consequences of Excitotoxicity

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Xenogeneic adrenal medulla graft rejection rather than survival leads to increased rat striatal tyrosine hydroxylase immunoreactivity

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p75 nerve growth factor receptor immunoreactivity in the human brainstem and spinal cord

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trk-immunoreactivity in the monkey central nervous system: forebrain

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α-Synuclein nonhuman primate models of Parkinson's disease

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α-synuclein aggregation reduces nigral myocyte enhancer Factor-2D in idiopathic and experimental Parkinson's disease ⬇️

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β-Secretase-1 elevation in aged monkey and Alzheimer's disease human cerebral cortex occurs around the vasculature in partnership with multisystem axon terminal pathogenesis and β-amyloid accumulation

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