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List of works by Ali Hemmati-Brivanlou

4 Use of Dominant Negative Constructs to Modulate Gene Expression

scientific article published on January 1, 1998

A 3D model of a human epiblast reveals BMP4-driven symmetry breaking

scientific article published on 01 July 2019

A Balance between Secreted Inhibitors and Edge Sensing Controls Gastruloid Self-Organization

scientific article

A Xenopus type I activin receptor mediates mesodermal but not neural specification during embryogenesis.

scientific article published in February 1997

A boost towards totipotency for stem cells

scientific article published on 01 June 2019

A full menu for stem-cell research

scientific article

A highly conserved lens transcriptional control element from the Pax-6 gene ⬇️

scientific article published on May 1, 1998

A method to recapitulate early embryonic spatial patterning in human embryonic stem cells

scientific article

A molecular basis for Smad specificity

scientific article published on 01 March 1999

A molecular basis for human embryonic stem cell pluripotency

scientific article published on January 2005

A post-mid-blastula transition requirement for TGFbeta signaling in early endodermal specification

scientific article published on 01 February 2000

A protein expressed in the growth cones of embryonic vertebrate neurons defines a new class of intermediate filament protein

scientific article published on September 1, 1992

A regulatory circuitry comprised of miR-302 and the transcription factors OCT4 and NR2F2 regulates human embryonic stem cell differentiation

scientific article published on 10 December 2010

A truncated activin receptor inhibits mesoderm induction and formation of axial structures in Xenopus embryos

scientific article published on October 15, 1992

A wave of WNT signaling balanced by secreted inhibitors controls primitive streak formation in micropattern colonies of human embryonic stem cells

scientific article published on 25 March 2019

APCDD1 is a novel Wnt inhibitor mutated in hereditary hypotrichosis simplex

scientific article

APOBEC2, a selective inhibitor of TGFβ signaling, regulates left-right axis specification during early embryogenesis.

scientific article published on 27 September 2010

An obligatory caravanserai stop on the silk road to neural induction: inhibition of BMP/GDF signaling

scientific article

At Last: Gene Editing in Human Embryos to Understand Human Development

scientific article published in November 2017

Author Correction: Self-organization of a human organizer by combined Wnt and Nodal signalling

scientific article published in Nature

Balancing BMP Signaling through Integrated Inputs into the Smad1 Linker

scientific article published on 01 February 2007

Caudalization of neural fate by tissue recombination and bFGF

scientific article published on 01 December 1995

Cell fate determination in embryonic ectoderm ⬇️

scientific article published on August 1, 1998

Cell fate specification and competence by Coco, a maternal BMP, TGFbeta and Wnt inhibitor

scientific article published on 01 April 2003

Cephalic expression and molecular characterization of Xenopus En-2 ⬇️

scientific article published on March 1, 1991

Chapter 20 Assays for Gene Function in Developing Xenopus Embryos

scientific article published on 01 January 1991

Characterization of Xenopus Phox2a and Phox2b defines expression domains within the embryonic nervous system and early heart field.

scientific article published in September 2004

Chick Models and Human-Chick Organizer Grafts

scientific article published on 01 January 2019

Chromosomal instability during neurogenesis in Huntington's disease.

scientific article

Cloning and developmental expression of Baf57 in Xenopus laevis

scientific article published in August 2002

Coco is a dual activity modulator of TGFβ signaling

scientific article published on 26 June 2015

Coco regulates dorsoventral specification of germ layers via inhibition of TGFβ signalling

scientific article published on 11 September 2013

Combined small-molecule inhibition accelerates the derivation of functional cortical neurons from human pluripotent stem cells.

scientific article

Comment on "Controlling long-term signaling: receptor dynamics determine attenuation and refractory behavior of the TGF-β pathway"-Smad2/3 activity does not predict the dynamics of transcription.

scientific article published on 23 September 2014

Comparing independent microarray studies: the case of human embryonic stem cells

scientific article

Concentration-dependent patterning of the Xenopus ectoderm by BMP4 and its signal transducer Smad1 ⬇️

scientific article published on August 1, 1997

Contribution of human embryonic stem cells to mouse blastocysts

scientific article published on 01 July 2006

Contributors

DRAGON, a bone morphogenetic protein co-receptor

scientific article

Dephosphorylation of the linker regions of Smad1 and Smad2/3 by small C-terminal domain phosphatases has distinct outcomes for bone morphogenetic protein and transforming growth factor-beta pathways.

scientific article

Discovery of novel isoforms of huntingtin reveals a new hominid-specific exon

scientific article published on 26 May 2015

Drosophila Goosecoid requires a conserved heptapeptide for repression of paired-class homeoprotein activators.

scientific article

Dynamics of TGF-β signaling reveal adaptive and pulsatile behaviors reflected in the nuclear localization of transcription factor Smad4 ⬇️

scientific article published on June 11, 2012

Embryoids, organoids and gastruloids: new approaches to understanding embryogenesis

scientific article published on March 2017

Embryonic expression and functional analysis of a Xenopus activin receptor

scientific article published on May 1, 1992

Embryonic expression of eph signalling factors in Xenopus

scientific article published in July 1996

Encoding of temporal signals by the TGF-β pathway and implications for embryonic patterning

scientific article

Epidermal induction and inhibition of neural fate by translation initiation factor 4AIII.

scientific article published in November 1997

Erratum FGF-mediated mesoderm induction involves the Src-family kinase Laloo

scientific article published in Nature

Expression cloning of Xenopus Os4, an evolutionarily conserved gene, which induces mesoderm and dorsal axis

scientific article published in November 2001

Expression of activin mRNA during early development in Xenopus laevis

scientific article

Expression of an engrailed-related protein is induced in the anterior neural ectoderm of early Xenopus embryos.

scientific article published in July 1989

FGF-20 and DKK1 are transcriptional targets of beta-catenin and FGF-20 is implicated in cancer and development

scientific article

FGF-mediated mesoderm induction involves the Src-family kinase Laloo

scientific article published in August 1998

Fluorescent labeling of endothelial cells allows in vivo, continuous characterization of the vascular development of Xenopus laevis

scientific article published on 01 February 2003

Follistatin, an antagonist of activin, is expressed in the Spemann organizer and displays direct neuralizing activity

scientific article published in April 1994

Function of the two Xenopus smad4s in early frog development

scientific article published on 14 August 2006

GDF3 at the crossroads of TGF-beta signaling

scientific article (publication date: May 2006)

GDF3 is a BMP inhibitor that can activate Nodal signaling only at very high doses

scientific article

GDF3, a BMP inhibitor, regulates cell fate in stem cells and early embryos

scientific article

GSK-3-selective inhibitors derived from Tyrian purple indirubins

scientific article

Gene expression profiling of osteoclast differentiation by combined suppression subtractive hybridization (SSH) and cDNA microarray analysis.

scientific article

Gene profiling during neural induction in Xenopus laevis: regulation of BMP signaling by post-transcriptional mechanisms and TAB3, a novel TAK1-binding protein

scientific article published in December 2002

Genomics and embryology in amphibians

scientific article

Guiding embryonic stem cells towards differentiation: lessons from molecular embryology

scientific article

Human SCNT Gets a Boost from Histone Demethylation

scientific article published in December 2015

Huntingtin is required for ciliogenesis and neurogenesis during early Xenopus development

scientific article published on 17 July 2015

Huntingtin protein is essential for mitochondrial metabolism, bioenergetics and structure in murine embryonic stem cells

scientific article

In vivo evidence for trigeminal nerve guidance by the cement gland in Xenopus

scientific article published on 01 September 1996

In vivo imaging of quantum dots encapsulated in phospholipid micelles

scientific article published on 01 November 2002

Induction of ectopic olfactory structures and bone morphogenetic protein inhibition by Rossy, a group XII secreted phospholipase A2.

scientific article

Induction of epidermis and inhibition of neural fate by Bmp-4 ⬇️

scientific article published on July 27, 1995

Inhibition of Cell Division and DNA Replication Impair Mouse-Naïve Pluripotency Exit

scientific article

Inhibition of activin receptor signaling promotes neuralization in Xenopus

scientific article published on 01 April 1994

Inhibitory control of neural differentiation in mammalian cells

scientific article published on May 1997

Lefty at the crossroads of "stemness" and differentiative events

scientific article

Lens induction by Pax-6 in Xenopus laevis

scientific article published in May 1997

Localization of specific mRNAs in Xenopus embryos by whole-mount in situ hybridization

scientific article

Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor

scientific article (publication date: 2004)

Manipulation of self-renewal in human embryonic stem cells through a novel pharmacological GSK-3 inhibitor.

scientific article

Mapping cell migrations and fates in a gastruloid model to the human primitive streak

scientific article published on 12 September 2019

MicroRNAs in early vertebrate development.

scientific article

Microarray Approach to Identify the Signaling Network Responsible for Self-Renewal of Human Embryonic Stem Cells

scientific article published on 20 May 2015

Microarray approach to identify the signaling network responsible for self-renewal of human embryonic stem cells

scientific article published in January 2006

Microarray-based analysis of early development in Xenopus laevis

scientific article published in August 2001

Modulation of FOXD3 activity in human embryonic stem cells directs pluripotency and paraxial mesoderm fates

scientific article published in October 2012

Molecular signature of human embryonic stem cells and its comparison with the mouse

scientific article published on August 2003

Most of the homeobox-containing Xhox 36 transcripts in early Xenopus embryos cannot encode a homeodomain protein

scientific article

Negative regulation of axis formation and Wnt signaling in Xenopus embryos by the F-box/WD40 protein beta TrCP.

scientific article

Neural Crest Induction by Xwnt7B in Xenopus ⬇️

scientific article published on February 1, 1998

Neural induction

scientific article

Neural induction and early patterning in vertebrates.

scientific article published on 15 October 2012

Neural induction in Xenopus laevis: evidence for the default model.

scientific article published on February 1997

Neural induction, the default model and embryonic stem cells

scientific article

Neural patterning in the vertebrate embryo

scientific article

OAZ uses distinct DNA- and protein-binding zinc fingers in separate BMP-Smad and Olf signaling pathways

scientific article

Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways.

scientific article published on October 1996

Pax6 induces ectopic eyes in a vertebrate

scientific article published in October 1999

Proposal of a model of mammalian neural induction

scientific article published on 2 June 2007

Region-specific neural induction of an engrailed protein by anterior notochord in Xenopus

scientific article published in November 1990

Regulation of Smad degradation and activity by Smurf2, an E3 ubiquitin ligase

scientific article

Regulation of epidermal induction by BMP2 and BMP7 signaling

scientific article published on 01 September 1997

Regulation of nodal and BMP signaling by tomoregulin-1 (X7365) through novel mechanisms

scientific article

Regulatory non-coding RNAs in pluripotent stem cells.

scientific article published on 11 July 2013

Role of MicroRNAs in Zygotic Genome Activation: Modulation of mRNA During Embryogenesis

scientific article

Role of YAP in early ectodermal specification and a Huntington's Disease model of human neurulation

scientific article published on 22 April 2022

SMAD7 directly converts human embryonic stem cells to telencephalic fate by a default mechanism.

scientific article

Samba, a Xenopus hnRNP expressed in neural and neural crest tissues

scientific article published in January 2009

Scaling of BMP gradients in Xenopus embryos

scientific article published in September 2009

Self-Organization of Spatial Patterning in Human Embryonic Stem Cells

scientific article published on 2 February 2016

Self-organization of a human organizer by combined Wnt and Nodal signalling

scientific article published in Nature

Self-organization of human dorsal-ventral forebrain structures by light induced SHH

scientific article published on 19 November 2021

Self-organization of human embryonic stem cells on micropatterns

scientific article published on 13 October 2016

Self-organization of the in vitro attached human embryo

scientific article published on 4 May 2016

Self-organizing neuruloids model developmental aspects of Huntington's disease in the ectodermal compartment

scientific article published on 09 September 2019

Signaling dynamics and embryonic development

scientific article published on 30 August 2012

Smad5 induces ventral fates in Xenopus embryo

scientific article published on April 1997

Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressor ⬇️

scientific article published on January 15, 1998

Stem cells. Setting standards for human embryonic stem cells

scientific article

Synthetic embryology: controlling geometry to model early mammalian development

scientific article published on 27 June 2018

Synthetic mRNAs: powerful tools for reprogramming and differentiation of human cells

scientific article published on 01 November 2010

TGF-beta signals and a pattern in Xenopus laevis endodermal development

scientific article

TGFbeta/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells

scientific article published on 9 February 2005

The BMP Inhibitor Coco Reactivates Breast Cancer Cells at Lung Metastatic Sites ⬇️

scientific article published on August 17, 2012

The Gata5 target, TGIF2, defines the pancreatic region by modulating BMP signals within the endoderm

scientific article published on 19 December 2007

The RNA-binding protein, Vg1RBP, is required for pancreatic fate specification.

scientific article published on April 2006

The generation of sex cells

scientific article

The latent-TGFbeta-binding-protein-1 (LTBP-1) is expressed in the organizer and regulates nodal and activin signaling

scientific article

The left-right axis is regulated by the interplay of Coco, Xnr1 and derrière in Xenopus embryos

scientific article

The miR-430/427/302 family controls mesendodermal fate specification via species-specific target selection

scientific article

The molecular circuitry underlying pluripotency in embryonic stem cells

scientific article published on 03 July 2012

The orphan receptor ALK7 and the Activin receptor ALK4 mediate signaling by Nodal proteins during vertebrate development

scientific article

Turning of retinal growth cones in a netrin-1 gradient mediated by the netrin receptor DCC.

scientific article published in December 1997

Twisted gastrulation can function as a BMP antagonist

scientific article published in March 2001

Unique players in the BMP pathway: small C-terminal domain phosphatases dephosphorylate Smad1 to attenuate BMP signaling.

scholarly article

Ventral ectoderm of Xenopus forms neural tissue, including hindbrain, in response to activin ⬇️

scientific article published on July 1, 1992

Ventral mesodermal patterning in Xenopus embryos: expression patterns and activities of BMP-2 and BMP-4

scientific article

Versatile selective kinase inhibitors: Chemistry and biology of indirubins

Vertebrate embryonic cells will become nerve cells unless told otherwise

scientific article

Vertebrate neural induction

scientific article published on January 1997

Vertebrate neural induction: inducers, inhibitors, and a new synthesis

scientific article published on May 1997

WNT signaling memory is required for ACTIVIN to function as a morphogen in human gastruloids

scientific article published on 12 October 2018

XFKH2, a Xenopus HNF-3 alpha homologue, exhibits both activin-inducible and autonomous phases of expression in early embryos

scientific article published in December 1993

XenDB: full length cDNA prediction and cross species mapping in Xenopus laevis

scientific article

Xenopus GDF6, a new antagonist of noggin and a partner of BMPs

scientific article (publication date: August 1999)

Xenopus Smad7 Inhibits both the Activin and BMP Pathways and Acts as a Neural Inducer ⬇️

scientific article published on June 1, 1998

Xenopus embryonic E2F is required for the formation of ventral and posterior cell fates during early embryogenesis

scientific article

Xenopus msx1 mediates epidermal induction and neural inhibition by BMP4 ⬇️

scientific article published on August 1, 1997

hPSC Modeling Reveals that Fate Selection of Cortical Deep Projection Neurons Occurs in the Subplate

scientific article published on 21 June 2018

miR-373 is regulated by TGFβ signaling and promotes mesendoderm differentiation in human Embryonic Stem Cells.

scientific article

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