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List of works by Seulki Lee

A facile, one-step nanocarbon functionalization for biomedical applications

scientific article

A nanoparticle formula for delivering siRNA or miRNAs to tumor cells in cell culture and in vivo.

scientific article

A near-infrared-fluorescence-quenched gold-nanoparticle imaging probe for in vivo drug screening and protease activity determination

scientific article

A new orally available glucagon-like peptide-1 receptor agonist, biotinylated exendin-4, displays improved hypoglycemic effects in db/db mice

scientific article

Activatable imaging probes with amplified fluorescent signals

scientific article published on 25 July 2008

Activatable molecular probes for cancer imaging

scientific article published on January 2010

Anti-cancer effect of Cordyceps militaris in human colorectal carcinoma RKO cells via cell cycle arrest and mitochondrial apoptosis

scientific article published on 4 July 2015

Antitumor efficacy of cisplatin-loaded glycol chitosan nanoparticles in tumor-bearing mice.

scientific article published on 26 December 2007

Biochemical, pharmaceutical and therapeutic properties of long-acting lithocholic acid derivatized exendin-4 analogs

scientific article published on 10 November 2009

Biodegradable DNA Nanoparticles that Provide Widespread Gene Delivery in the Brain

scientific article published on 17 December 2015

Bioorthogonal Copper Free Click Chemistry for Labeling and Tracking of Chondrocytes In Vivo

scientific article published in March 2016

Caspase sensitive gold nanoparticle for apoptosis imaging in live cells

scientific article published on 11 October 2010

Cathepsin B-Specific Metabolic Precursor for In Vivo Tumor-Specific Fluorescence Imaging

scientific article published on 20 October 2016

Cationic analog of deoxycholate as an oral delivery carrier for ceftriaxone

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Chimeric ferritin nanocages for multiple function loading and multimodal imaging

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Co-delivery of VEGF and Bcl-2 dual-targeted siRNA polymer using a single nanoparticle for synergistic anti-cancer effects in vivo

scientific article published on 22 August 2015

Combining portable Raman probes with nanotubes for theranostic applications

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Dark quenched matrix metalloproteinase fluorogenic probe for imaging osteoarthritis development in vivo.

scientific article published on 26 August 2008

Delivery of tumor-homing TRAIL sensitizer with long-acting TRAIL as a therapy for TRAIL-resistant tumors

scientific article

Design and fabrication of N-alkyl-polyethylenimine-stabilized iron oxide nanoclusters for gene delivery

scientific article published on January 2012

Design of "smart" probes for optical imaging of apoptosis

scientific article published on 22 June 2011

Diabetes correction in pancreatectomized canines by orally absorbable insulin-deoxycholate complex

scientific article published on June 2010

Direct observation of aluminium ions produced via pulsed laser ablation in liquid: a ‘turn-on’ fluorescence study

scientific article published on October 19, 2012

Dual-functional, receptor-targeted fluorogenic probe for in vivo imaging of extracellular protease expressions

scientific article

Dual-modality probes for in vivo molecular imaging.

scientific article published on March 2009

Dynamic PET and Optical Imaging and Compartment Modeling using a Dual-labeled Cyclic RGD Peptide Probe

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Echogenic Glycol Chitosan Nanoparticles for Ultrasound-Triggered Cancer Theranostics

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Effect of injection routes on the biodistribution, clearance, and tumor uptake of carbon dots

scientific article published on 06 June 2013

Effect of polymer molecular weight on the tumor targeting characteristics of self-assembled glycol chitosan nanoparticles

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Efficacy of orally active chemical conjugate of low molecular weight heparin and deoxycholic acid in rats, mice and monkeys

scientific article published on 23 February 2006

Evaluation of absorption of heparin-DOCA conjugates on the intestinal wall using a surface plasmon resonance

scientific article

FUNCTIONAL NANOPARTICLES FOR MOLECULAR IMAGING GUIDED GENE DELIVERY

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Functional analysis of the BRI1 receptor kinase by Thr-for-Ser substitution in a regulatory autophosphorylation site.

scientific article published on 30 July 2015

Glycol chitosan nanoparticles as specialized cancer therapeutic vehicles: sequential delivery of doxorubicin and Bcl-2 siRNA.

scientific article

HSA Coated Iron Oxide Nanoparticles as Drug Delivery Vehicles for Cancer Therapy

scientific article published on August 22, 2011

HSA coated MnO nanoparticles with prominent MRI contrast for tumor imaging

scientific article published on August 23, 2010

Heparin-coated gold nanoparticles for liver-specific CT imaging.

scientific article published in December 2009

High-affinity peptide against MT1-MMP for in vivo tumor imaging

scientific article published on February 2, 2011

High-sensitivity nanosensors for biomarker detection

scientific article published on 20 December 2011

Highly PEGylated DNA Nanoparticles Provide Uniform and Widespread Gene Transfer in the Brain

scientific article

Highly poly(ethylene) glycolylated islets improve long-term islet allograft survival without immunosuppressive medication.

scientific article published in August 2007

Hybrid Ferritin Nanoparticles as Activatable Probes for Tumor Imaging

scientific article published on January 7, 2011

Hydrophobically modified glycol chitosan nanoparticles-encapsulated camptothecin enhance the drug stability and tumor targeting in cancer therapy

scientific article published on 7 February 2008

Improved antitumor activity and tumor targeting of NH(2)-terminal-specific PEGylated tumor necrosis factor-related apoptosis-inducing ligand

scientific article published on June 2010

Improved biological half-life and anti-tumor activity of TNF-related apoptosis-inducing ligand (TRAIL) using PEG-exposed nanoparticles

scientific article published on February 18, 2011

Improved intrapulmonary delivery of site-specific PEGylated salmon calcitonin: optimization by PEG size selection

scientific article published on 22 October 2007

Improved peroral delivery of glucagon-like peptide-1 by site-specific biotin modification: design, preparation, and biological evaluation

scientific article published on 2 August 2007

In Vivo Optical Imaging of Membrane-Type Matrix Metalloproteinase (MT-MMP) Activity

scientific article published on December 5, 2011

In vivo time-dependent gene expression of cationic lipid-based emulsion as a stable and biocompatible non-viral gene carrier

scientific article published on 19 February 2008

Inhibition of notch signalling ameliorates experimental inflammatory arthritis.

scientific article published on 19 November 2013

Inorganic Nanoparticles for Multimodal Molecular Imaging

scientific article published on February 1, 2011

In vivo stem cell tracking with imageable nanoparticles that bind bioorthogonal chemical receptors on the stem cell surface

scientific article published on June 2017

Light–matter interaction and polarization of single ZnO nanowire lasers

scientific article published on July 2, 2012

Long-term multimodal imaging of tumor draining sentinel lymph nodes using mesoporous silica-based nanoprobes

scientific article published on 16 March 2012

Manipulating the power of an additional phase: a flower-like Au-Fe3O4 optical nanosensor for imaging protease expressions in vivo

scientific article

Mesenchymal stem cell-based cell engineering with multifunctional mesoporous silica nanoparticles for tumor delivery

scientific article published on December 8, 2012

Mix to validate: a facile, reversible PEGylation for fast screening of potential therapeutic proteins in vivo

scientific article published on 05 June 2013

Moving theranostics trom bench to bedside in an interdisciplinary research team

scientific article published in February 2011

Multiplex imaging of an intracellular proteolytic cascade by using a broad-spectrum nanoquencher

scientific article published on 2 January 2012

Nano-sized metabolic precursors for heterogeneous tumor-targeting strategy using bioorthogonal click chemistry in vivo

scientific article

Nanoparticle-based theranostic agents

scientific article published on August 4, 2010

Nanotheranostics for personalized medicine

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Noninvasive monitoring of orthotopic glioblastoma therapy response using RGD-conjugated iron oxide nanoparticles

scientific article published on 3 May 2012

Noninvasive monitoring of pulmonary fibrosis by targeting matrix metalloproteinases (MMPs).

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Nuclear mapping of nanodrug delivery systems in dynamic cellular environments

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N‐Alkyl‐PEI‐Functionalized Iron Oxide Nanoclusters for Efficient siRNA Delivery

scientific article published on August 22, 2011

Oral Delivery of Ionic Complex of Ceftriaxone with Bile Acid Derivative in Non-human Primates

scientific article published on 05 January 2013

Oral delivery of chemical conjugates of heparin and deoxycholic acid in aqueous formulation

scientific article published on January 2006

PEG-transferrin conjugated TRAIL (TNF-related apoptosis-inducing ligand) for therapeutic tumor targeting

scientific article published on July 21, 2012

PEGylated TNF-related apoptosis-inducing ligand (TRAIL) analogues: pharmacokinetics and antitumor effects

scientific article published on 22 July 2011

PEGylated TNF-related apoptosis-inducing ligand (TRAIL) for effective tumor combination therapy

scientific article published on August 19, 2011

PEGylated TNF-related apoptosis-inducing ligand (TRAIL)-loaded sustained release PLGA microspheres for enhanced stability and antitumor activity

scientific article published on November 6, 2010

PET/NIRF/MRI triple functional iron oxide nanoparticles

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Peptide-based probes for targeted molecular imaging

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Peptides and peptide hormones for molecular imaging and disease diagnosis

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Pharmacokinetic and pharmacodynamic evaluation of site-specific PEGylated glucagon-like peptide-1 analogs as flexible postprandial-glucose controllers

scientific article published in April 2009

Pharmacokinetics of a new, orally available ceftriaxone formulation in physical complexation with a cationic analogue of bile acid in rats

scientific article

Polymeric nanoparticle-based activatable near-infrared nanosensor for protease determination in vivo

scientific article published on December 2009

Polymeric nanoparticles for protein kinase activity

scientific article

Precise Targeting of Liver Tumor Using Glycol Chitosan Nanoparticles: Mechanisms, Key Factors, and Their Implications

scientific article published on 21 September 2016

Preparation and characterization of self-assembled nanoparticles of heparin-deoxycholic acid conjugates

scientific article

Preparation and characterization of water-soluble albumin-bound curcumin nanoparticles with improved antitumor activity

scientific article published on October 28, 2010

Preparation and structural, biochemical, and pharmaceutical characterizations of bile acid-modified long-acting exendin-4 derivatives

scientific article published on November 2009

Preparation, characterization, and application of biotinylated and biotin-PEGylated glucagon-like peptide-1 analogues for enhanced oral delivery

scientific article published on 14 December 2007

Protease Activity: Meeting Its Theranostic Potential

scientific article published on January 1, 2012

Protease imaging of human atheromata captures molecular information of atherosclerosis, complementing anatomic imaging

scientific article

Protease-activated drug development

scientific article published on 8 February 2012

Protein-phosphorylation-responsive polymeric nanoparticles for imaging protein kinase activities in single living cells

scientific article published in January 2007

ROS-generating TiO2 nanoparticles for non-invasive sonodynamic therapy of cancer

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Rational design of matrix metalloproteinase-13 activatable probes for enhanced specificity

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Real time, high resolution video imaging of apoptosis in single cells with a polymeric nanoprobe.

scientific article published on 10 January 2011

Real-Time Video Imaging of Protease Expression In Vivo

scientific article published on January 12, 2011

Real-time monitoring of caspase cascade activation in living cells

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Self-assembled glycol chitosan nanoparticles for the sustained and prolonged delivery of antiangiogenic small peptide drugs in cancer therapy

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Site-specific PEGylated Exendin-4 modified with a high molecular weight trimeric PEG reduces steric hindrance and increases type 2 antidiabetic therapeutic effects

scientific article published on 9 November 2012

Stability and bioactivity of nanocomplex of TNF-related apoptosis-inducing ligand.

scientific article published on 23 July 2008

Stability and cellular uptake of polymerized siRNA (poly-siRNA)/polyethylenimine (PEI) complexes for efficient gene silencing

scientific article published on 14 October 2009

Sticky nanoparticles: a platform for siRNA delivery by a bis(zinc(II) dipicolylamine)-functionalized, self-assembled nanoconjugate

scientific article published on 23 November 2011

Synthesis and biological properties of insulin-deoxycholic acid chemical conjugates

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Synthesis, characterization, and pharmacokinetic studies of PEGylated glucagon-like peptide-1.

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Systemic PEGylated TRAIL treatment ameliorates liver cirrhosis in rats by eliminating activated hepatic stellate cells

scientific article published on 28 December 2015

T1-Weighted MR imaging of liver tumor by gadolinium-encapsulated glycol chitosan nanoparticles without non-specific toxicity in normal tissues

scientific article published on 26 April 2016

The design and application of fluorophore–gold nanoparticle activatable probes

scientific article published on March 7, 2011

The genotype-dependent influence of functionalized multiwalled carbon nanotubes on fetal development

scientific article

Theranostic nanoparticles based on PEGylated hyaluronic acid for the diagnosis, therapy and monitoring of colon cancer

scientific article published on 9 June 2012

Theranostic nanoplatforms for simultaneous cancer imaging and therapy: current approaches and future perspectives

scientific article published on December 2011

Tricaprylin microemulsion for oral delivery of low molecular weight heparin conjugates

scientific article published on June 2005

Tumor-homing glycol chitosan/polyethylenimine nanoparticles for the systemic delivery of siRNA in tumor-bearing mice

scientific article published on 22 February 2010

Tumor-homing multifunctional nanoparticles for cancer theragnosis: Simultaneous diagnosis, drug delivery, and therapeutic monitoring

scientific article published on 24 April 2010

Tumor-homing photosensitizer-conjugated glycol chitosan nanoparticles for synchronous photodynamic imaging and therapy based on cellular on/off system

scientific article published on 3 March 2011

Tumor-homing poly-siRNA/glycol chitosan self-cross-linked nanoparticles for systemic siRNA delivery in cancer treatment

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Ultrasmall near-infrared non-cadmium quantum dots for in vivo tumor imaging

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What is the future of PEGylated therapies?

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