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List of works by Kwang-Hyun Cho

A Regulated Double-Negative Feedback Decodes the Temporal Gradient of Input Stimulation in a Cell Signaling Network

scientific article

A checkpoints capturing timing-robust Boolean model of the budding yeast cell cycle regulatory network

scientific article

A design principle underlying the synchronization of oscillations in cellular systems

scientific article published on 26 January 2010

A hybrid systems framework for cellular processes

scientific article published on 15 January 2005

A system-level investigation into the cellular toxic response mechanism mediated by AhR signal transduction pathway

scientific article published on 7 July 2010

A unified framework for unraveling the functional interaction structure of a biomolecular network based on stimulus-response experimental data

scientific article

Advanced significance analysis of microarray data based on weighted resampling: a comparative study and application to gene deletions in Mycobacterium bovis

scientific article

An Efficient Steady-State Analysis Method for Large Boolean Networks with High Maximum Node Connectivity

scientific article published on 30 December 2015

An efficient algorithm for identifying primary phenotype attractors of a large-scale Boolean network

scientific article

Analysis of feedback loops and robustness in network evolution based on Boolean models

scientific article

Attractor Landscape Analysis Reveals Feedback Loops in the p53 Network That Control the Cellular Response to DNA Damage ⬇️

scientific article published on November 20, 2012

Attractor landscape analysis of colorectal tumorigenesis and its reversion

scientific article

Coherent coupling of feedback loops: a design principle of cell signaling networks

scientific article published on 2 July 2008

Combined Positive and Negative Feedback Allows Modulation of Neuronal Oscillation Frequency during Sensory Processing

scientific article published on 01 November 2018

Coupled positive and negative feedback circuits form an essential building block of cellular signaling pathways

scientific article published in January 2007

Coupled positive feedbacks provoke slow induction plus fast switching in apoptosis

scientific article published on 21 May 2007

Discovery of a kernel for controlling biomolecular regulatory networks

scientific article published on January 2013

Dynamic network rewiring determines temporal regulatory functions in Drosophila melanogaster development processes

scientific article

Dynamical analysis of the calcium signaling pathway in cardiac myocytes based on logarithmic sensitivity analysis

scientific article published in May 2008

Dynamical characteristics of bacteria clustering by self-generated attractants

scientific article published on 6 August 2007

Dynamics of biological systems: role of systems biology in medical research

scientific article published on November 2006

ELECANS—an integrated model development environment for multiscale cancer systems biology ⬇️

scientific article published on February 6, 2013

Evolutionary design principles and functional characteristics based on kingdom-specific network motifs ⬇️

scientific article published on November 11, 2010

Evolutionary design principles of modules that control cellular differentiation: consequences for hysteresis and multistationarity

scientific article

Functional roles of multiple feedback loops in extracellular signal-regulated kinase and Wnt signaling pathways that regulate epithelial-mesenchymal transition

scientific article

Hub genes with positive feedbacks function as master switches in developmental gene regulatory networks

scientific article

Identification of Gene Networks with Time Delayed Regulation Based on Temporal Expression Profiles

scientific article published in September 2015

Impaired coupling of local and global functional feedbacks underlies abnormal synchronization and negative symptoms of schizophrenia ⬇️

scientific article published on April 10, 2013

In silico identification of the key components and steps in IFN-gamma induced JAK-STAT signaling pathway

scientific article published in February 2005

Inferring biomolecular regulatory networks from phase portraits of time-series expression profiles

scientific article published on 22 May 2006

Inferring gene regulatory networks from temporal expression profiles under time-delay and noise

scientific article published on 6 April 2007

Integrative analysis of time course microarray data and DNA sequence data via log-linear models for identifying dynamic transcriptional regulatory networks

scientific article published on January 1, 2013

Interlinked mutual inhibitory positive feedbacks induce robust cellular memory effects

scientific article published on 19 September 2007

Investigations into the analysis and modeling of the TNF alpha-mediated NF-kappa B-signaling pathway

scientific article

Investigations into the design principles in the chemotactic behavior of Escherichia coli

scientific article published on 4 September 2007

Investigations into the relationship between feedback loops and functional importance of a signal transduction network based on Boolean network modeling

scientific article

Least-squares methods for identifying biochemical regulatory networks from noisy measurements

scientific article published on 10 January 2007

Level sets and minimum volume sets of probability density functions

Linear time-varying models can reveal non-linear interactions of biomolecular regulatory networks using multiple time-series data

scientific article

MLK3 is part of a feedback mechanism that regulates different cellular responses to reactive oxygen species

scientific article

Microarray data clustering based on temporal variation: FCV with TSD preclustering.

scientific article

Modeling and simulation of intracellular dynamics: choosing an appropriate framework

scientific article

Modelling gene expression time-series with radial basis function neural networks

article

Modelling the dynamics of signalling pathways

scientific article published on January 2008

Multiple roles of the NF-kappaB signaling pathway regulated by coupled negative feedback circuits

scientific article published on 5 May 2009

Network-based identification of feedback modules that control RhoA activity and cell migration

scientific article published on 16 March 2015

Optimal sampling time selection for parameter estimation in dynamic pathway modeling

scientific article published in July 2004

Positive- and negative-feedback regulations coordinate the dynamic behavior of the Ras-Raf-MEK-ERK signal transduction pathway

scientific article published in February 2009

Quantitative analysis of robustness and fragility in biological networks based on feedback dynamics

scientific article published on 19 February 2008

Quantitative evaluation and reversion analysis of the attractor landscapes of an intracellular regulatory network for colorectal cancer

scientific article

Recurrent connections form a phase-locking neuronal tuner for frequency-dependent selective communication

scientific article published on January 2013

Reduction of Complex Signaling Networks to a Representative Kernel ⬇️

scientific article published on May 31, 2011

Robustness and evolvability of the human signaling network

scientific article (publication date: July 2014)

Silence on the relevant literature and errors in implementation

scientific article published in April 2015

Spatiotemporal network motif reveals the biological traits of developmental gene regulatory networks in Drosophila melanogaster ⬇️

scientific article published on May 1, 2012

System-level investigation into the regulatory mechanism of the calcineurin/NFAT signaling pathway

scientific article published on 5 February 2008

The APC network regulates the removal of mutated cells from colonic crypts

scientific article published on 27 March 2014

The biphasic behavior of incoherent feed-forward loops in biomolecular regulatory networks

scientific article published in November 2008

The co-regulation mechanism of transcription factors in the human gene regulatory network ⬇️

scientific article published on July 13, 2012

The core regulation module of stress-responsive regulatory networks in yeast ⬇️

scientific article published on July 10, 2012

The crossregulation between ERK and PI3K signaling pathways determines the tumoricidal efficacy of MEK inhibitor

scientific article published on 4 May 2012

The dynamic systems approach to control and regulation of intracellular networks

scientific article

The hidden switches underlying RORα-mediated circuits that critically regulate uncontrolled cell proliferation

scientific article published on 15 May 2014

The multi-step phosphorelay mechanism of unorthodox two-component systems in E. coli realizes ultrasensitivity to stimuli while maintaining robustness to noises

scientific article published on 16 November 2006

The phenotype control kernel of a biomolecular regulatory network

scientific article published on 5 April 2018

The regulatory circuits for hysteretic switching in cellular signal transduction pathways

scientific article published on 30 May 2012

The reverse control of irreversible biological processes

scientific article

The role of dynamic stimulation pattern in the analysis of bistable intracellular networks

scientific article

The statistical distribution of the intensity of pixels within spots of DNA microarrays: what is the appropriate single-value representative?

scientific article published in January 2003

Unraveling the functional interaction structure of a biomolecular network through alternate perturbation of initial conditions

scientific article published on 27 January 2007

Unravelling the functional interaction structure of a cellular network from temporal slope information of experimental data

scientific article

Why have serine/threonine/tyrosine kinases been evolutionarily selected in eukaryotic signaling cascades?

scientific article published on 23 February 2008

Wnt pathway mutations selected by optimal beta-catenin signaling for tumorigenesis

scientific article published on 5 June 2006

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