List of works - Olaf Kutsch

8-Hydroxyquinolines Are Boosting Agents of Copper-Related Toxicity in Mycobacterium tuberculosis

scientific article published on 18 July 2016

A Macrophage Infection Model to Predict Drug Efficacy Against Mycobacterium Tuberculosis

scientific article published on 21 June 2016

A high-throughput drug screening system for HIV-1 transcription inhibitors

scientific article published on 10 July 2006

A screen to identify small molecule inhibitors of protein-protein interactions in mycobacteria

scientific article

Adjusting transgene expression levels in lymphocytes with a set of inducible promoters

scientific article

An AP-1 binding site in the enhancer/core element of the HIV-1 promoter controls the ability of HIV-1 to establish latent infection

scientific article published on 12 December 2012

Bis-anthracycline antibiotics inhibit human immunodeficiency virus type 1 transcription

scientific article published on May 2004

CD154-CD40-induced reactivation of latent HIV-1 infection ⬇️

scientific article published on September 15, 2003

Combinatorial phenotypic screen uncovers unrecognized family of extended thiourea inhibitors with copper-dependent anti-staphylococcal activity

scientific article

Copper complexation screen reveals compounds with potent antibiotic properties against methicillin-resistant Staphylococcus aureus

scientific article

Copper-boosting compounds: a novel concept for antimycobacterial drug discovery

scientific article published on 17 December 2012

Determinants of the establishment of human immunodeficiency virus type 1 latency

scientific article

Direct and quantitative single-cell analysis of human immunodeficiency virus type 1 reactivation from latency

scientific article

Disulfiram and Copper Ions Kill Mycobacterium tuberculosis in a Synergistic Manner

scientific article

Dynamics of HIV-1 recombination in its natural target cells

scholarly article

Effective Non-Viral Delivery of siRNA to Acute Myeloid Leukemia Cells with Lipid-Substituted Polyethylenimines ⬇️

scientific article published on August 31, 2012

Effective activation alleviates the replication block of CCR5-tropic HIV-1 in chimpanzee CD4+ lymphocytes

scientific article published on 12 September 2009

Facts and fiction: cellular models for high throughput screening for HIV-1 reactivating drugs

scientific article published on December 2011

High throughput drug screening for human immunodeficiency virus type 1 reactivating compounds

scientific article published on April 2007

Hit-and-run stimulation: a novel concept to reactivate latent HIV-1 infection without cytokine gene induction

scientific article published on 10 June 2010

Host factor transcriptional regulation contributes to preferential expression of HIV type 1 in IL-4-producing CD4 T cells

scientific article published on 8 August 2012

Human immunodeficiency virus type 2 (HIV-2)/HIV-1 envelope chimeras detect high titers of broadly reactive HIV-1 V3-specific antibodies in human plasma

scientific article

Inhibition of Tat-mediated HIV-1 replication and neurotoxicity by novel GSK3-beta inhibitors

scientific article published on 22 April 2011

Kinase control prevents HIV-1 reactivation in spite of high levels of induced NF-κB activity

scientific article published on 15 February 2012

Mycobacterium tuberculosis exploits the PPM1A signaling pathway to block host macrophage apoptosis

scientific article published on 8 February 2017

Nef-Mediated Suppression of T Cell Activation Was Lost in a Lentiviral Lineage that Gave Rise to HIV-1

scientific article

Optimization of HIV-1 infectivity assays

scientific article published on November 2007

Protein phosphatase, Mg2+/Mn2+-dependent 1A controls the innate antiviral and antibacterial response of macrophages during HIV-1 and Mycobacterium tuberculosis infection

scientific article

RNAP II processivity is a limiting step for HIV-1 transcription independent of orientation to and activity of endogenous neighboring promoters

scientific article

Regulatory CD4 T cells inhibit HIV-1 expression of other CD4 T cell subsets via interactions with cell surface regulatory proteins

scientific article published on 8 January 2018

Selected Drugs with Reported Secondary Cell-Differentiating Capacity Prime Latent HIV-1 Infection for Reactivation ⬇️

scientific article published on June 13, 2012

Stable Phenotypic Changes of the Host T Cells Are Essential to the Long-Term Stability of Latent HIV-1 Infection

scientific article published on 15 April 2015

Suppressor of cytokine signaling 3 inhibits antiviral IFN-beta signaling to enhance HIV-1 replication in macrophages

scientific article published on 14 July 2010

T-cell line for HIV drug screening using EGFP as a quantitative marker of HIV-1 replication

scientific article published on January 2006

Targeted Disruption of the CCR5 Gene in Human Hematopoietic Stem Cells Stimulated by Peptide Nucleic Acids ⬇️

scientific article published on September 23, 2011

Targeting CXCR4/SDF-1 axis by lipopolymer complexes of siRNA in acute myeloid leukemia

scientific article published on 29 December 2015

Tat inhibitors, a new approach: interview with Olaf Kutsch, Ph.D. Interview by John S. James.

scientific article published in January 2005

The host cell side of latent HIV-1 infection

scientific article published in August 2015

The phosphatase PPM1A controls monocyte-to-macrophage differentiation

scientific article published on 17 January 2018

The quality of chimpanzee T-cell activation and simian immunodeficiency virus/human immunodeficiency virus susceptibility achieved via antibody-mediated T-cell receptor/CD3 stimulation is a function of the anti-CD3 antibody isotype

scientific article published on 30 July 2008

Tumor necrosis factor-related apoptosis-inducing ligand induces caspase-dependent interleukin-8 expression and apoptosis in human astroglioma cells

scientific article

Validating a Firefly Luciferase-Based High-Throughput Screening Assay for Antimalarial Drug Discovery ⬇️

scientific article published on November 3, 2011

List of works by Olaf Kutsch

8-Hydroxyquinolines Are Boosting Agents of Copper-Related Toxicity in Mycobacterium tuberculosis

A Macrophage Infection Model to Predict Drug Efficacy Against Mycobacterium Tuberculosis

A high-throughput drug screening system for HIV-1 transcription inhibitors

A screen to identify small molecule inhibitors of protein-protein interactions in mycobacteria

Adjusting transgene expression levels in lymphocytes with a set of inducible promoters

An AP-1 binding site in the enhancer/core element of the HIV-1 promoter controls the ability of HIV-1 to establish latent infection

Bis-anthracycline antibiotics inhibit human immunodeficiency virus type 1 transcription

CD154-CD40-induced reactivation of latent HIV-1 infection ⬇️

Combinatorial phenotypic screen uncovers unrecognized family of extended thiourea inhibitors with copper-dependent anti-staphylococcal activity

Copper complexation screen reveals compounds with potent antibiotic properties against methicillin-resistant Staphylococcus aureus

Copper-boosting compounds: a novel concept for antimycobacterial drug discovery

Determinants of the establishment of human immunodeficiency virus type 1 latency

Direct and quantitative single-cell analysis of human immunodeficiency virus type 1 reactivation from latency

Disulfiram and Copper Ions Kill Mycobacterium tuberculosis in a Synergistic Manner

Dynamics of HIV-1 recombination in its natural target cells

Effective Non-Viral Delivery of siRNA to Acute Myeloid Leukemia Cells with Lipid-Substituted Polyethylenimines ⬇️

Effective activation alleviates the replication block of CCR5-tropic HIV-1 in chimpanzee CD4+ lymphocytes

Facts and fiction: cellular models for high throughput screening for HIV-1 reactivating drugs

High throughput drug screening for human immunodeficiency virus type 1 reactivating compounds

Hit-and-run stimulation: a novel concept to reactivate latent HIV-1 infection without cytokine gene induction

Host factor transcriptional regulation contributes to preferential expression of HIV type 1 in IL-4-producing CD4 T cells

Human immunodeficiency virus type 2 (HIV-2)/HIV-1 envelope chimeras detect high titers of broadly reactive HIV-1 V3-specific antibodies in human plasma

Inhibition of Tat-mediated HIV-1 replication and neurotoxicity by novel GSK3-beta inhibitors

Kinase control prevents HIV-1 reactivation in spite of high levels of induced NF-κB activity

Mycobacterium tuberculosis exploits the PPM1A signaling pathway to block host macrophage apoptosis

Nef-Mediated Suppression of T Cell Activation Was Lost in a Lentiviral Lineage that Gave Rise to HIV-1

Optimization of HIV-1 infectivity assays

Protein phosphatase, Mg2+/Mn2+-dependent 1A controls the innate antiviral and antibacterial response of macrophages during HIV-1 and Mycobacterium tuberculosis infection

RNAP II processivity is a limiting step for HIV-1 transcription independent of orientation to and activity of endogenous neighboring promoters

Regulatory CD4 T cells inhibit HIV-1 expression of other CD4 T cell subsets via interactions with cell surface regulatory proteins

Selected Drugs with Reported Secondary Cell-Differentiating Capacity Prime Latent HIV-1 Infection for Reactivation ⬇️

Stable Phenotypic Changes of the Host T Cells Are Essential to the Long-Term Stability of Latent HIV-1 Infection

Suppressor of cytokine signaling 3 inhibits antiviral IFN-beta signaling to enhance HIV-1 replication in macrophages

T-cell line for HIV drug screening using EGFP as a quantitative marker of HIV-1 replication

Targeted Disruption of the CCR5 Gene in Human Hematopoietic Stem Cells Stimulated by Peptide Nucleic Acids ⬇️

Targeting CXCR4/SDF-1 axis by lipopolymer complexes of siRNA in acute myeloid leukemia

Tat inhibitors, a new approach: interview with Olaf Kutsch, Ph.D. Interview by John S. James.

The host cell side of latent HIV-1 infection

The phosphatase PPM1A controls monocyte-to-macrophage differentiation

The quality of chimpanzee T-cell activation and simian immunodeficiency virus/human immunodeficiency virus susceptibility achieved via antibody-mediated T-cell receptor/CD3 stimulation is a function of the anti-CD3 antibody isotype

Tumor necrosis factor-related apoptosis-inducing ligand induces caspase-dependent interleukin-8 expression and apoptosis in human astroglioma cells

Validating a Firefly Luciferase-Based High-Throughput Screening Assay for Antimalarial Drug Discovery ⬇️