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List of works by John Miners

Application of Homology Modeling to Generate CYP1A1 Mutants with Enhanced Activation of the Cancer Chemotherapeutic Prodrug Dacarbazine

scientific article published on August 4, 2011

Assessment of inter-individual variability in predicted phenytoin clearance

scientific article published in December 2009

Baculovirus-mediated expression of cytochrome P4502C8 and human NADPH-cytochrome P450 reductase : optimization of protein expression

scientific article published on February 1, 1998

Biochemical validation of self-reported caffeine consumption during caffeine fading

scientific article published on 01 February 1988

Caffeine as a probe for human cytochromes P450: validation using cDNA-expression, immunoinhibition and microsomal kinetic and inhibitor techniques

scientific article published on August 1, 1992

Characterization of Niflumic Acid as a Selective Inhibitor of Human Liver Microsomal UDP-Glucuronosyltransferase 1A9: Application to the Reaction Phenotyping of Acetaminophen Glucuronidation

scientific article published on January 18, 2011

Cimetidine interaction with warfarin

scientific article published on September 22, 1979

Cytochrome P4502C9: an enzyme of major importance in human drug metabolism

scientific article published on June 1, 1998

Differential disposition of intra-renal generated and preformed glucuronides: studies with 4-methylumbelliferone and 4-methylumbelliferyl glucuronide in the filtering and nonfiltering isolated perfused rat kidney

scientific article published on 01 March 2011

Effect of Albumin on Human Liver Microsomal and Recombinant CYP1A2 Activities: Impact on In Vitro-In Vivo Extrapolation of Drug Clearance

scientific article published on February 13, 2012

Effects of Ketamine on Human UDP-Glucuronosyltransferases In Vitro Predict Potential Drug-Drug Interactions Arising from Ketamine Inhibition of Codeine and Morphine Glucuronidation

scientific article published on May 6, 2011

Failure of ‘therapeutic’ doses of beta-adrenoceptor antagonists to alter the disposition of tolbutamide and lignocaine

scientific article published on December 1, 1984

In vitro–in vivo extrapolation of CYP2C8-catalyzed paclitaxel 6α-hydroxylation: effects of albumin on in vitro kinetic parameters and assessment of interindividual variability in predicted clearance

scientific article published on 09 February 2011

Inhibition of human hepatic cytochrome P4502E1 by azole antifungals, CNS-active drugs and nonsteroidal anti-inflammatory agents

scientific article published on 01 March 1998

Perturbation of paracetamol urinary metabolic ratios by urine flow rate

scientific article published on October 1, 1992

Ranitidine disposition in patients with renal impairment

scientific article published on December 1, 1983

Response to in vitro and physiologically-based pharmacokinetic assessment of the drug-drug interaction potential of canagliflozin.

scientific article published on 3 November 2017

Selective inhibitory effects of nifedipine and verapamil on oxidative metabolism: effects on theophylline

scientific article published on March 1, 1988

Simultaneous determination of pentoxifylline and its hydroxy metabolite in plasma by high-performance liquid chromatography

scientific article published on September 11, 1981

Stereospecific High-Performance Liquid Chromatographic Assay for the Enantiomers of Phenylpropanolamine in Human Plasma

scientific article published on July 1, 1991

The UDP-glucuronosyltransferases: Their role in drug metabolism and detoxification

scientific article published on 07 March 2013

The glycosidation of xenobiotics and endogenous compounds: Versatility and redundancy in the UDP glycosyltransferase superfamily

scientific article published on February 1, 2012