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List of works by C P Reynolds

13-cis-retinoic acid (NSC 122758) in the treatment of children with metastatic neuroblastoma unresponsive to conventional chemotherapy: report from the Childrens Cancer Study Group.

scientific article published on January 1992

A Comprehensive Safety Trial of Chimeric Antibody 14.18 With GM-CSF, IL-2, and Isotretinoin in High-Risk Neuroblastoma Patients Following Myeloablative Therapy: Children's Oncology Group Study ANBL0931.

scientific article published on 18 June 2018

A Phase I New Approaches to Neuroblastoma Therapy Study of Buthionine Sulfoximine and Melphalan With Autologous Stem Cells for Recurrent/Refractory High-Risk Neuroblastoma

scientific article

A Phase I study of human gamma interferon gene-transduced tumor cells in patients with neuroblastoma

scientific article published on 01 February 1998

A comprehensively characterized cell line panel highly representative of clinical ovarian high-grade serous carcinomas

scientific article published on 10 June 2016

A feasibility trial of a video intervention to improve informed consent for parents of children with leukemia

scientific article

A fluorescence microplate cytotoxicity assay with a 4-log dynamic range that identifies synergistic drug combinations

scientific article published on March 2007

A panel of monoclonal antibodies which discriminate neuroblastoma from Ewing's sarcoma, rhabdomyosarcoma, neuroepithelioma, and hematopoietic malignancies.

scientific article

A phase I clinical trial of the hu14.18-IL2 (EMD 273063) as a treatment for children with refractory or recurrent neuroblastoma and melanoma: a study of the Children's Oncology Group

scientific article

A simple and sensitive ribonucleotide reductase assay ⬇️

scientific article published on January 1, 1998

Abstract 2493: Enhanced activity of fenretinide/-LYM-X-SORBTM(4-HPR/LXS) oral powder in combination with ketoconazole and vincristine against recurrent neuroblastoma xenografts

Activity of MM-398, nanoliposomal irinotecan (nal-IRI), in Ewing's family tumor xenografts is associated with high exposure of tumor to drug and high SLFN11 expression

scientific article

Activity of irinotecan and temozolomide in the presence of O6-methylguanine-DNA methyltransferase inhibition in neuroblastoma pre-clinical models

scientific article

Activity of vincristine, L-ASP, and dexamethasone against acute lymphoblastic leukemia is enhanced by the BH3-mimetic ABT-737 in vitro and in vivo.

scientific article published on 29 May 2007

Allogeneic versus autologous purged bone marrow transplantation for neuroblastoma: a report from the Childrens Cancer Group.

scientific article published in November 1994

Alternative lengthening of telomeres in neuroblastoma cell lines is associated with a lack of MYCN genomic amplification and with p53 pathway aberrations

scientific article published on 3 May 2014

Antagonism of buthionine sulfoximine cytotoxicity for human neuroblastoma cell lines by hypoxia is reversed by the bioreductive agent tirapazamine

scientific article published on April 2003

Antagonism of cytotoxic chemotherapy in neuroblastoma cell lines by 13-cis-retinoic acid is mediated by the antiapoptotic Bcl-2 family proteins

scientific article

Antenatal detection of recurrence of Majewski dwarf (short rib-polydactyly syndrome type II Majewski)

article

Anti-GD2 antibody with GM-CSF, interleukin-2, and isotretinoin for neuroblastoma

scientific article

Antidisialoganglioside/granulocyte macrophage-colony-stimulating factor fusion protein facilitates neutrophil antibody-dependent cellular cytotoxicity and depends on FcgammaRII (CD32) and Mac-1 (CD11b/CD18) for enhanced effector cell adhesion and az

scientific article published in June 2002

Antitumor activity of hu14.18-IL2 in patients with relapsed/refractory neuroblastoma: a Children's Oncology Group (COG) phase II study

scientific article

Antitumour activity and tolerability of an EphA2-targeted nanotherapeutic in multiple mouse models

scientific article published on 05 April 2019

Ascorbic acid enhances the cytotoxic effect of 6-hydroxydopamine for human neuroblastoma cell lines

scientific article published on 01 October 1981

Assessing combinations of cytotoxic agents using leukemia cell lines

scientific article

Assessing growth and response to therapy in murine tumor models.

scientific article

Bcl-2 inhibitors: targeting mitochondrial apoptotic pathways in cancer therapy

scientific article

Biological classification of cell lines derived from human extra-cranial neural tumors

scientific article published on January 1, 1988

Bone marrow transplantation for poor prognosis neuroblastoma

scientific article published in January 1988

Broad Spectrum Activity of the Checkpoint Kinase 1 Inhibitor Prexasertib as a Single Agent or Chemopotentiator Across a Range of Preclinical Pediatric Tumor Models

scientific article published on 18 December 2018

Buthionine sulfoximine and myeloablative concentrations of melphalan overcome resistance in a melphalan-resistant neuroblastoma cell line.

scientific article published on November 2001

Buthionine sulphoximine alone and in combination with melphalan (L-PAM) is highly cytotoxic for human neuroblastoma cell lines

scientific article

Caspase-dependent Mcl-1 cleavage and effect of Mcl-1 phosphorylation in ABT-737-induced apoptosis in human acute lymphoblastic leukemia cell lines.

scientific article

Catecholamine fluorescence and tissue culture morphology. Technics in the diagnosis of neuroblastoma

scientific article published on 01 March 1981

Cell type-specific expression and negative regulation by retinoic acid of the human N-myc promoter in neuroblastoma cells

scientific article published on 01 April 1992

Ceramide signaling in fenretinide-induced endothelial cell apoptosis

scientific article published on 17 October 2002

Ceramide synthesis and metabolism as a target for cancer therapy.

scientific article published on April 2004

Characterization and drug resistance patterns of Ewing's sarcoma family tumor cell lines

scientific article (publication date: 2013)

Characterization of human neuroblastoma cell lines established before and after therapy

scientific article published in March 1986

Characterization of human neuroblastoma cell lines that lack N-myc gene amplification

scientific article published on 01 January 1988

Chronic stress, leukocyte subpopulations, and humoral response to latent viruses

scientific article published on 01 January 1989

Clinical development of fenretinide as an antineoplastic drug: Pharmacology perspectives.

scientific article

Collection, storage, and infusion of stem cells in children with high-risk neuroblastoma: saving for a rainy day.

scientific article

Comparison of 13-cis-retinoic acid to trans-retinoic acid using human neuroblastoma cell lines

scientific article

Comparison of autologous and allogeneic bone marrow transplantation for neuroblastoma.

scientific article published in January 1994

Comparison of primary neuroblastoma tumors and derivative early-passage cell lines using genome-wide single nucleotide polymorphism array analysis.

scientific article

Consolidation chemoradiotherapy and autologous bone marrow transplantation versus continued chemotherapy for metastatic neuroblastoma: a report of two concurrent Children's Cancer Group studies

scientific article published in September 1996

Corrigendum: A Comprehensive Safety Trial of Chimeric Antibody 14.18 With GM-CSF, IL-2, and Isotretinoin in High-Risk Neuroblastoma Patients Following Myeloablative Therapy: Children's Oncology Group Study ANBL0931

scientific article published on 16 July 2018

Corrigendum: Transcriptomic profiling of 39 commonly-used neuroblastoma cell lines

scientific article published on 5 December 2017

Credentialing preclinical pediatric xenograft models using gene expression and tissue microarray analysis

scientific article published on January 2007

Crizotinib Synergizes with Chemotherapy in Preclinical Models of Neuroblastoma

scientific article published on 5 October 2015

Cross-resistance of topoisomerase I and II inhibitors in neuroblastoma cell lines

scientific article published on January 2000

Cytotoxic activity of difluoromethylornithine compared with fenretinide in neuroblastoma cell lines

scientific article published on 24 September 2018

Cytotoxicity and molecular activity of fenretinide and metabolites in T-cell lymphoid malignancy, neuroblastoma, and ovarian cancer cell lines in physiological hypoxia

scientific article published on 01 February 2019

DIMSCAN: a microcomputer fluorescence-based cytotoxicity assay for preclinical testing of combination chemotherapy.

scientific article

Decreased expression of N-myc precedes retinoic acid-induced morphological differentiation of human neuroblastoma.

scientific article published in January 1985

Depletion of glutathione by buthionine sulfoxine is cytotoxic for human neuroblastoma cell lines via apoptosis

scientific article

Depletion of neuroblastoma cells from bone marrow with monoclonal antibodies and magnetic immunobeads

scientific article published on 01 January 1985

Detailed molecular analysis of 1p36 in neuroblastoma

article

Detection and treatment of minimal residual disease in high-risk neuroblastoma.

scientific article published on June 2004

Determination of subcutaneous tumor size in athymic (nude) mice

scientific article

Differentiating agents in pediatric malignancies: retinoids in neuroblastoma.

scientific article published in November 2000

Disialoganglioside-specific human natural killer cells are effective against drug-resistant neuroblastoma.

scientific article

Double-alkylator non-total-body irradiation regimen with autologous hematopoietic stem-cell transplantation in pediatric solid tumors

scientific article published on 01 March 1998

Drug resistance in human neuroblastoma cell lines correlates with clinical therapy

scientific article

Drug resistance patterns of human neuroblastoma cell lines derived from patients at different phases of therapy.

scientific article

DrugPath: a database for academic investigators to match oncology molecular targets with drugs in development

scientific article published on 25 March 2014

E-cadherin cell-cell adhesion in ewing tumor cells mediates suppression of anoikis through activation of the ErbB4 tyrosine kinase

scientific article published on April 2007

Efficacy and pharmacokinetic/pharmacodynamic evaluation of the Aurora kinase A inhibitor MLN8237 against preclinical models of pediatric cancer.

scientific article published on 30 March 2011

Engraftment after myeloablative doses of 131I-metaiodobenzylguanidine followed by autologous bone marrow transplantation for treatment of refractory neuroblastoma.

scientific article published in June 1998

Evaluating response to antineoplastic drug combinations in tissue culture models.

scientific article

Evaluation of Alternative In Vivo Drug Screening Methodology: A Single Mouse Analysis

scientific article published on 5 August 2016

Evaluation of arsenic trioxide by the pediatric preclinical testing program with a focus on Ewing sarcoma.

scientific article published on 7 February 2012

Evaluation of cytarabine against Ewing sarcoma xenografts by the pediatric preclinical testing program ⬇️

scientific article published on December 1, 2010

Evidence for an Age Cutoff Greater Than 365 Days for Neuroblastoma Risk Group Stratification in the Children's Oncology Group

article

Expression of protein gene product 9.5 and tyrosine hydroxylase in childhood small round cell tumors

scientific article published on February 2000

Expression of retinoic acid receptors alpha, beta, and gamma in human neuroblastoma cell lines

scientific article published on 01 January 1994

Expression of the dbl proto-oncogene in Ewing's sarcomas

scientific article published on 01 July 1989

Expression profiling of favorable and unfavorable neuroblastomas.

scientific article

Extensive Proliferation of Human Cancer Cells with Ever-Shorter Telomeres.

scientific article published in June 2017

Fenretinide cytotoxicity for Ewing's sarcoma and primitive neuroectodermal tumor cell lines is decreased by hypoxia and synergistically enhanced by ceramide modulators

scientific article published on August 2004

Fenretinide metabolism in humans and mice: utilizing pharmacological modulation of its metabolic pathway to increase systemic exposure

scientific article

Fenretinide sensitizes multidrug-resistant human neuroblastoma cells to antibody-independent and ch14.18-mediated NK cell cytotoxicity.

scientific article

Fenretinide via NOXA Induction, Enhanced Activity of the BCL-2 Inhibitor Venetoclax in High BCL-2-Expressing Neuroblastoma Preclinical Models

scientific article published on 04 September 2019

Flow cytometry analysis of single-strand DNA damage in neuroblastoma cell lines using the F7-26 monoclonal antibody.

scientific article

GABAergic system gene expression predicts clinical outcome in patients with neuroblastoma

scientific article published on 01 October 2004

Ganglioside GM2/GD2 synthetase mRNA is a marker for detection of infrequent neuroblastoma cells in bone marrow

scientific article published on August 2001

Genomic Profiling of Childhood Tumor Patient-Derived Xenograft Models to Enable Rational Clinical Trial Design

scientific article published on 01 November 2019

Growth characteristics of neuroblastoma in vitro correlate with patient survival

scientific article published on 01 January 1980

High levels of p19/nm23 protein in neuroblastoma are associated with advanced stage disease and with N-myc gene amplification

scientific article

Histone deacetylase 1 gene expression and sensitization of multidrug-resistant neuroblastoma cell lines to cytotoxic agents by depsipeptide

scientific article published on 10 July 2007

Homozygous deletion of CDKN2A (p16INK4a/p14ARF) but not within 1p36 or at other tumor suppressor loci in neuroblastoma

scientific article published on January 2001

Hsp27 expression in neuroblastoma: correlation with disease stage

scientific article published on 01 May 1994

Human neuroblastoma cell lines regain catecholamine fluorescence when xenografted into athymic (nude) mice

scientific article published on 01 October 1996

Human neuroblastoma cell lines that express N-myc without gene amplification.

scientific article published on December 1993

Human neuroblastoma: Glial induced morphological differentiation.

scientific article published in August 1975

Hydrophilic interaction liquid chromatography-tandem mass spectrometric approach for simultaneous determination of safingol and D-erythro-sphinganine in human plasma

scientific article published on 22 February 2019

Hypercalcemia: a dose-limiting toxicity associated with 13-cis-retinoic acid.

scientific article published on November 1993

Identical expression of cell surface membrane antigens on two parent and eighteen cloned cell lines derived from two different neuroblastoma metastases of the same patient

scientific article published in September 1986

Immunohistologic detection and phenotyping of neuroblastoma cells in bone marrow using cytoplasmic neuron specific enolase and cell surface antigens.

scientific article published in January 1985

Improved oral delivery of N-(4-hydroxyphenyl)retinamide with a novel LYM-X-SORB organized lipid complex

scientific article published on May 2007

In vitro testing of chemosensitivity in physiological hypoxia.

scientific article

Increase of ceramide and induction of mixed apoptosis/necrosis by N-(4-hydroxyphenyl)- retinamide in neuroblastoma cell lines

scientific article published on July 1999

Increased N-myc expression following progressive growth of human neuroblastoma.

scientific article published in August 1986

Induction of catecholamine fluorescence in human neuroblastoma cell lines transplanted into nude mice.

scientific article

Induction of neurite outgrowth in the IMR-32 human neuroblastoma cell line by nerve growth factor.

scientific article published in January 1981

Inhibition of the insulin-like growth factor I receptor by epigallocatechin gallate blocks proliferation and induces the death of Ewing tumor cells.

scientific article

Initial Testing (Stage 1) of MK-8242-A Novel MDM2 Inhibitor-by the Pediatric Preclinical Testing Program.

scientific article published on 30 May 2016

Initial Testing of NSC 750854, a Novel Purine Analog, Against Pediatric Tumor Models by the Pediatric Preclinical Testing Program

scientific article

Initial solid tumor testing (stage 1) of AZD1480, an inhibitor of Janus kinases 1 and 2 by the pediatric preclinical testing program

scientific article

Initial testing (Stage 1) of AT13387, an HSP90 inhibitor, by the pediatric preclinical testing program.

scientific article

Initial testing (Stage 1) of the antibody-maytansinoid conjugate, IMGN901 (Lorvotuzumab mertansine), by the pediatric preclinical testing program

scientific article

Initial testing (stage 1) by the pediatric preclinical testing program of RO4929097, a γ-secretase inhibitor targeting notch signaling

scientific article published on 16 August 2011

Initial testing (stage 1) of AZD6244 (ARRY-142886) by the Pediatric Preclinical Testing Program.

scientific article

Initial testing (stage 1) of BAL101553, a novel tubulin binding agent, by the pediatric preclinical testing program

scientific article published on 18 November 2014

Initial testing (stage 1) of LCL161, a SMAC mimetic, by the Pediatric Preclinical Testing Program

scientific article published on 16 June 2011

Initial testing (stage 1) of M6620 (formerly VX-970), a novel ATR inhibitor, alone and combined with cisplatin and melphalan, by the Pediatric Preclinical Testing Program.

scientific article published on 17 September 2017

Initial testing (stage 1) of SGI-1776, a PIM1 kinase inhibitor, by the pediatric preclinical testing program.

scientific article published on 2 November 2011

Initial testing (stage 1) of a monoclonal antibody (SCH 717454) against the IGF-1 receptor by the pediatric preclinical testing program

scientific article published on June 2008

Initial testing (stage 1) of eribulin, a novel tubulin binding agent, by the pediatric preclinical testing program

scientific article

Initial testing (stage 1) of ganetespib, an Hsp90 inhibitor, by the Pediatric Preclinical Testing Program

scientific article

Initial testing (stage 1) of lapatinib by the pediatric preclinical testing program

scientific article published on October 2009

Initial testing (stage 1) of mapatumumab (HGS-ETR1) by the pediatric preclinical testing program

scientific article published on February 2010

Initial testing (stage 1) of sunitinib by the pediatric preclinical testing program

scientific article

Initial testing (stage 1) of temozolomide by the pediatric preclinical testing program

scientific article

Initial testing (stage 1) of the Akt inhibitor GSK690693 by the pediatric preclinical testing program.

scientific article

Initial testing (stage 1) of the BH3 mimetic ABT-263 by the pediatric preclinical testing program

scientific article published on June 2008

Initial testing (stage 1) of the IGF-1 receptor inhibitor BMS-754807 by the pediatric preclinical testing program.

scientific article

Initial testing (stage 1) of the PARP inhibitor BMN 673 by the pediatric preclinical testing program: PALB2 mutation predicts exceptional in vivo response to BMN 673.

scientific article published on 27 September 2014

Initial testing (stage 1) of the Polo-like kinase inhibitor volasertib (BI 6727), by the Pediatric Preclinical Testing Program.

scientific article

Initial testing (stage 1) of the anti-microtubule agents cabazitaxel and docetaxel, by the pediatric preclinical testing program.

scientific article published on 7 July 2015

Initial testing (stage 1) of the curaxin CBL0137 by the pediatric preclinical testing program.

scientific article published on 21 September 2016

Initial testing (stage 1) of the cyclin dependent kinase inhibitor SCH 727965 (dinaciclib) by the pediatric preclinical testing program.

scientific article

Initial testing (stage 1) of the histone deacetylase inhibitor, quisinostat (JNJ-26481585), by the Pediatric Preclinical Testing Program

scientific article

Initial testing (stage 1) of the investigational mTOR kinase inhibitor MLN0128 by the pediatric preclinical testing program

scientific article

Initial testing (stage 1) of the kinesin spindle protein inhibitor ispinesib by the pediatric preclinical testing program.

scientific article published on December 2009

Initial testing (stage 1) of the mTOR inhibitor rapamycin by the pediatric preclinical testing program.

scientific article

Initial testing (stage 1) of the mTOR kinase inhibitor AZD8055 by the pediatric preclinical testing program

scientific article

Initial testing (stage 1) of the multi-targeted kinase inhibitor sorafenib by the pediatric preclinical testing program

scientific article published on December 2010

Initial testing (stage 1) of the notch inhibitor PF-03084014, by the pediatric preclinical testing program

scientific article

Initial testing (stage 1) of the phosphatidylinositol 3' kinase inhibitor, SAR245408 (XL147) by the pediatric preclinical testing program.

scientific article

Initial testing (stage 1) of the polyamine analog PG11047 by the pediatric preclinical testing program.

scientific article

Initial testing (stage 1) of the proteasome inhibitor bortezomib by the pediatric preclinical testing program.

scientific article published on January 2008

Initial testing (stage 1) of the topoisomerase II inhibitor pixantrone, by the pediatric preclinical testing program.

scientific article published on 26 October 2013

Initial testing (stage 1) of vorinostat (SAHA) by the pediatric preclinical testing program.

scientific article published on September 2009

Initial testing of JNJ-26854165 (Serdemetan) by the pediatric preclinical testing program.

scientific article published on 15 September 2011

Initial testing of VS-4718, a novel inhibitor of focal adhesion kinase (FAK), against pediatric tumor models by the Pediatric Preclinical Testing Program.

scientific article published on 27 October 2016

Initial testing of a monoclonal antibody (IMC-A12) against IGF-1R by the Pediatric Preclinical Testing Program.

scientific article

Initial testing of aplidin by the pediatric pre-clinical testing program.

scientific article published on September 2009

Initial testing of cisplatin by the pediatric preclinical testing program

scientific article published on May 2008

Initial testing of dasatinib by the pediatric preclinical testing program

scientific article

Initial testing of lenalidomide by the pediatric preclinical testing program

scientific article published on 25 February 2011

Initial testing of the CENP-E inhibitor GSK923295A by the pediatric preclinical testing program

scientific article

Initial testing of the MDM2 inhibitor RG7112 by the Pediatric Preclinical Testing Program

scientific article

Initial testing of the VEGFR inhibitor AZD2171 by the pediatric preclinical testing program

scientific article published on March 2008

Initial testing of the aurora kinase A inhibitor MLN8237 by the Pediatric Preclinical Testing Program (PPTP).

scientific article

Initial testing of the hypoxia-activated prodrug PR-104 by the pediatric preclinical testing program.

scientific article

Initial testing of the investigational NEDD8-activating enzyme inhibitor MLN4924 by the pediatric preclinical testing program.

scientific article published on 19 October 2011

Initial testing of the replication competent Seneca Valley virus (NTX-010) by the pediatric preclinical testing program

scientific article

Initial testing of topotecan by the pediatric preclinical testing program.

scientific article

Integrated genomic analyses identify ARID1A and ARID1B alterations in the childhood cancer neuroblastoma

scientific article

Intensive chemoradiotherapy and autologous bone marrow transplantation for poor prognosis neuroblastoma

scientific article published on 01 January 1991

Isolation of human nerve growth factor from placental tissue

scientific article published on 01 April 1978

Liquid chromatography method for quantifying N-(4-hydroxyphenyl)retinamide and N-(4-methoxyphenyl)retinamide in tissues

scientific article

Long-term results for children with high-risk neuroblastoma treated on a randomized trial of myeloablative therapy followed by 13-cis-retinoic acid: a children's oncology group study

scientific article

Loss of p53 function confers high-level multidrug resistance in neuroblastoma cell lines

scientific article

Lytic bone lesions in human neuroblastoma xenograft involve osteoclast recruitment and are inhibited by bisphosphonate.

scientific article published in June 2003

MYC transcription activation mediated by OCT4 as a mechanism of resistance to 13-cisRA-mediated differentiation in neuroblastoma

scientific article published on 14 May 2020

Mechanism of synergy of N-(4-hydroxyphenyl)retinamide and ABT-737 in acute lymphoblastic leukemia cell lines: Mcl-1 inactivation.

scientific article

Metabolic characteristics of 13-cis-retinoic acid (isotretinoin) and anti-tumour activity of the 13-cis-retinoic acid metabolite 4-oxo-13-cis-retinoic acid in neuroblastoma

scientific article

Metabolism of orthotopic mouse brain tumor models.

scientific article

Microcomputer software and interface for control of a microscope scanning stage

scientific article published on 01 February 1988

Microfluidic Separation of Lymphoblasts for the Isolation of Acute Lymphoblastic Leukemia Using the Human Transferrin Receptor as a Capture Target.

scientific article published on 28 June 2017

Mithramycin induces promoter reprogramming and differentiation of rhabdoid tumor

scientific article published on 17 December 2020

Mitochondrial Bcl-2 family dynamics define therapy response and resistance in neuroblastoma

scientific article published on May 2012

Model system for removing neuroblastoma cells from bone marrow using monoclonal antibodies and magnetic immunobeads

scientific article

Modulation of Glucocorticoid Resistance in Pediatric T-cell Acute Lymphoblastic Leukemia by Increasing BIM Expression with the PI3K/mTOR Inhibitor BEZ235

scientific article

Modulation of cell surface antigens accompanies morphological differentiation of human neuroblastoma cell lines

scientific article published on 01 January 1985

Molecular characterization of the pediatric preclinical testing panel

scientific article

Multidrug resistance-associated protein 1 (MRP1) expression in neuroblastoma cell lines and primary tumors

scientific article published in December 2000

Multiple defects of the nerve growth factor receptor in human neuroblastomas

scientific article published on January 1991

Multiple defects of the nerve growth factor receptor in human neuroblastomas.

scientific article published on September 1990

Myeloablative chemoradiotherapy versus continued chemotherapy for high risk neuroblastoma.

scientific article published in January 1994

N-(4-hydroxyphenyl)retinamide elevates ceramide in neuroblastoma cell lines by coordinate activation of serine palmitoyltransferase and ceramide synthase

scientific article

N-(4-hydroxyphenyl)retinamide increases ceramide and is cytotoxic to acute lymphoblastic leukemia cell lines, but not to non-malignant lymphocytes.

scientific article

N-myc gene amplification in neuroblastoma is associated with altered phosphorylation of a proliferation related polypeptide (Op18).

scientific article published on November 1990

N-myc protein expression in small round cell tumors

scientific article published on 01 January 1988

NGF effects on human neuroblastoma lines: a model system

scientific article published on 01 January 1982

National Cancer Institute pediatric preclinical testing program: model description for in vitro cytotoxicity testing

scientific article

Nerve growth factor induces neurite outgrowth in a clone derived from an NGF-insensitive human neuroblastoma cell line.

scientific article

Neutrophils are cytotoxic and growth-inhibiting for neuroblastoma cells with an anti-GD2 antibody but, without cytotoxicity, can be growth-stimulating.

scientific article published on February 2000

Novel cell lines established from pediatric brain tumors.

scientific article

Oncogene MYCN regulates localization of NKT cells to the site of disease in neuroblastoma

scientific article published in September 2007

Oral fenretinide in biochemically recurrent prostate cancer: a California cancer consortium phase II trial

scientific article published in January 2009

Outcome after reduced chemotherapy for intermediate-risk neuroblastoma

scientific article

Outcome after surgery alone or with restricted use of chemotherapy for patients with low-risk neuroblastoma: results of Children's Oncology Group study P9641.

scientific article

Outcome of high-risk stage 3 neuroblastoma with myeloablative therapy and 13-cis-retinoic acid: a report from the Children's Oncology Group

scientific article published on January 2009

P450 inhibitor ketoconazole increased the intratumor drug levels and antitumor activity of fenretinide in human neuroblastoma xenograft models.

scientific article

PCNA levels in neuroblastoma are increased in tumors with an amplified N-myc gene and in metastatic stage tumors

scientific article published on 01 January 1993

Patterns of relapse after autologous purged bone marrow transplantation for neuroblastoma: a Childrens Cancer Group pilot study.

scientific article published in November 1993

Pharmacodynamic and genomic markers associated with response to the XPO1/CRM1 inhibitor selinexor (KPT-330): A report from the pediatric preclinical testing program.

scientific article

Pharmacokinetic modeling of an induction regimen for in vivo combined testing of novel drugs against pediatric acute lymphoblastic leukemia xenografts.

scientific article

Pharmacokinetic studies of 13-cis-retinoic acid in pediatric patients with neuroblastoma following bone marrow transplantation.

scientific article published in January 1996

Phase I Study of Fenretinide Delivered Intravenously in Patients with Relapsed or Refractory Hematologic Malignancies: A California Cancer Consortium Trial

scientific article

Phase I dose escalation of 131I-metaiodobenzylguanidine with autologous bone marrow support in refractory neuroblastoma

scientific article

Phase I dose escalation of iodine-131-metaiodobenzylguanidine with myeloablative chemotherapy and autologous stem-cell transplantation in refractory neuroblastoma: a new approaches to Neuroblastoma Therapy Consortium Study.

scientific article published in January 2006

Phase I study of vorinostat in combination with isotretinoin in patients with refractory/recurrent neuroblastoma: A new approaches to Neuroblastoma Therapy (NANT) trial

scientific article published on 30 March 2018

Phase I trial of 13-cis-retinoic acid in children with neuroblastoma following bone marrow transplantation

scientific article

Phase I trial of fenretinide delivered orally in a novel organized lipid complex in patients with relapsed/refractory neuroblastoma: a report from the New Approaches to Neuroblastoma Therapy (NANT) consortium.

scientific article

Phase I trial of fenretinide lym-x-sorb oral powder in adults with solid tumors and lymphomas

scientific article published on 01 March 2011

Phase I trial of oral fenretinide in children with high-risk solid tumors: a report from the Children's Oncology Group (CCG 09709).

scientific article

Phase I trial of oral irinotecan and temozolomide for children with relapsed high-risk neuroblastoma: a new approach to neuroblastoma therapy consortium study

scientific article

Phase II study of oral capsular 4-hydroxyphenylretinamide (4-HPR/fenretinide) in pediatric patients with refractory or recurrent neuroblastoma: a report from the Children's Oncology Group

scientific article published on 9 September 2011

Pilot study of intravenous melphalan combined with continuous infusion L-S,R-buthionine sulfoximine for children with recurrent neuroblastoma.

scientific article

Possible differential diagnosis of neuroblastoma from rhabdomyosarcoma and Ewing's sarcoma by using a panel of monoclonal antibodies

scientific article published in April 1985

Preservation of high glycolytic phenotype by establishing new acute lymphoblastic leukemia cell lines at physiologic oxygen concentration

scientific article

Probable fatal drug interaction between intravenous fenretinide, ceftriaxone, and acetaminophen: a case report from a New Approaches to Neuroblastoma (NANT) Phase I study.

scientific article

Prognostic value of immunocytologic detection of bone marrow metastases in neuroblastoma

scientific article published on 01 January 1991

Purged versus non-purged peripheral blood stem-cell transplantation for high-risk neuroblastoma (COG A3973): a randomised phase 3 trial

scientific article published on 25 July 2013

Pyrazoloacridine is active in multidrug-resistant neuroblastoma cell lines with nonfunctional p53.

scientific article published on August 2003

Quantitative tumor cell content of bone marrow and blood as a predictor of outcome in stage IV neuroblastoma: a Children's Cancer Group Study.

scientific article published in December 2000

Ras and Seppuku in neuroblastoma

scientific article published on 01 March 2002

Reactive Oxygen Species Mediates the Synergistic Activity of Fenretinide Combined with the Microtubule Inhibitor ABT-751 against Multidrug-Resistant Recurrent Neuroblastoma Xenografts.

scientific article published on 16 August 2016

Reactive Oxygen Species-Mediated Synergism of Fenretinide and Romidepsin in Preclinical Models of T-cell Lymphoid Malignancies.

scientific article published on 23 January 2017

Removal of neuroblastoma cells from bone marrow with monoclonal antibodies and magnetic immunobeads

scientific article published on 01 January 1986

Response of neuroblastoma to retinoic acid in vitro and in vivo

scientific article published on January 1991

Retinoic-acid-resistant neuroblastoma cell lines show altered MYC regulation and high sensitivity to fenretinide.

scientific article published in December 2000

Retinoid therapy of childhood cancer.

scientific article

Retinoid therapy of high-risk neuroblastoma.

scientific article

Role of myeloablative therapy in improved outcome for high risk neuroblastoma: Review of recent children's cancer group results ⬇️

scientific article published on January 1, 1995

Selective toxicity of 6-hydroxydopamine and ascorbate for human neuroblastoma in vitro: a model for clearing marrow prior to autologous transplant

scientific article published on April 1982

Sensitive detection of neuroblastoma cells in bone marrow for monitoring the efficacy of marrow purging procedures

scientific article published on 01 January 1985

Sodium thiosulfate administered six hours after cisplatin does not compromise antineuroblastoma activity.

scientific article

Spotlight on dinutuximab in the treatment of high-risk neuroblastoma: development and place in therapy

article

Stage 1 testing and pharmacodynamic evaluation of the HSP90 inhibitor alvespimycin (17-DMAG, KOS-1022) by the pediatric preclinical testing program.

scientific article published on July 2008

Stage 2 combination testing of rapamycin with cytotoxic agents by the Pediatric Preclinical Testing Program

scientific article

Synergism of buthionine sulfoximine and melphalan against neuroblastoma cell lines derived after disease progression

scientific article

Synergistic activity of PARP inhibition by talazoparib (BMN 673) with temozolomide in pediatric cancer models in the pediatric preclinical testing program.

scientific article

Synergistic activity of fenretinide and the Bcl-2 family protein inhibitor ABT-737 against human neuroblastoma

scientific article

Synergistic cytotoxicity in solid tumor cell lines between N-(4-hydroxyphenyl)retinamide and modulators of ceramide metabolism

scientific article published on December 2000

Synergistic cytotoxicity of buthionine sulfoximine (BSO) and intensive melphalan (L-PAM) for neuroblastoma cell lines established at relapse after myeloablative therapy

scientific article published in August 2002

Targeted delivery in primary and metastatic brain tumors: summary report of the seventh annual meeting of the Blood-Brain Barrier Disruption Consortium

scientific article

Targeted inhibition of histone H3K27 demethylation is effective in high-risk neuroblastoma

scientific article published on 01 May 2018

Telomerase activity by TRAP assay and telomerase RNA (hTR) expression are predictive of outcome in neuroblastoma

scientific article published in December 2000

Telomerase expression in primary neuroblastomas

scientific article

Telomere maintenance mechanisms define clinical outcome in high-risk neuroblastoma

scientific article published on 14 April 2020

Testing of new agents in childhood cancer preclinical models: meeting summary

scientific article published on 01 December 2002

Testing of the Akt/PKB inhibitor MK-2206 by the Pediatric Preclinical Testing Program.

scientific article published on 18 November 2011

Testing of the topoisomerase 1 inhibitor Genz-644282 by the pediatric preclinical testing program.

scientific article

The O6-methyguanine-DNA methyltransferase inhibitor O6-benzylguanine enhanced activity of temozolomide + irinotecan against models of high-risk neuroblastoma

scientific article published on 14 December 2020

The activity of zoledronic Acid on neuroblastoma bone metastasis involves inhibition of osteoclasts and tumor cell survival and proliferation.

scientific article

The diagnostic dilemma of the "small round cell neoplasm": catecholamine fluorescence and tissue culture morphology as markers for neuroblastoma.

scientific article published in November 1981

The glutathione synthesis inhibitor buthionine sulfoximine synergistically enhanced melphalan activity against preclinical models of multiple myeloma

scientific article

The majority of total nuclear-encoded non-ribosomal RNA in a human cell is 'dark matter' un-annotated RNA

scientific article

The majority of total nuclear-encoded non-ribosomal RNA in a human cell is 'dark matter' un-annotated RNA.

scientific article

The pediatric preclinical testing program: description of models and early testing results.

scientific article published in December 2007

The targetable kinase PIM1 drives ALK inhibitor resistance in high-risk neuroblastoma independent of MYCN status

scientific article published on 28 November 2019

Tirapazamine cytotoxicity for neuroblastoma is p53 dependent.

scientific article published on April 2005

Toxicity assessment of molecularly targeted drugs incorporated into multiagent chemotherapy regimens for pediatric acute lymphocytic leukemia (ALL): review from an international consensus conference

scientific article

Transcriptomic profiling of 39 commonly-used neuroblastoma cell lines.

scientific article published on 28 March 2017

Transduction of green fluorescent protein increased oxidative stress and enhanced sensitivity to cytotoxic drugs in neuroblastoma cell lines

scientific article published in September 2003

Transplantation of human neuroblastoma cells, catecholaminergic and non-catecholaminergic: effects on rotational behavior in Parkinson's rat model ⬇️

scientific article published on April 1, 1992

Treatment of high-risk neuroblastoma with intensive chemotherapy, radiotherapy, autologous bone marrow transplantation, and 13-cis-retinoic acid. Children's Cancer Group

scientific article

Treatment of high-risk solid tumors of childhood with intensive therapy and autologous bone marrow transplantation

scientific article published on April 1991

Treatment of neuroblastoma patients with antiganglioside GD2 antibody plus interleukin-2 induces antibody-dependent cellular cytotoxicity against neuroblastoma detected in vitro

scientific article published on January 1994

Vorinostat and fenretinide synergize in preclinical models of T-cell lymphoid malignancies

scientific article published on 19 October 2020

miR-15a-5p, miR-15b-5p, and miR-16-5p inhibit tumor progression by directly targeting MYCN in neuroblastoma

scientific article published on 29 November 2019

p53 mutations and loss of p53 function confer multidrug resistance in neuroblastoma

scientific article

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