Search filters

List of works by Michael Parnham

'In vivo' models to study interactions between the arachidonate cascade and granulomatous inflammation

scientific article published on 01 January 1980

4 Ds in health research-working together toward rapid precision medicine

scientific article published on 18 September 2019

A machine-learned analysis of human gene polymorphisms modulating persisting pain points to major roles of neuroimmune processes

article

A multi-centre, double-blind comparative study of the efficacy and safety of aceclofenac and diclofenac in the treatment of rheumatoid arthritis

scientific article published on 01 January 1995

A polyether sponge constituent which is antioxidant, anti-inflammatory and increases prostaglandin concentrations at the inflamed site

scientific article published on 01 December 1977

Accelerated healing of excisional skin wounds by PL 14736 in alloxan-hyperglycemic rats.

scientific article

Aceclofenac in rheumatoid arthritis: a useful and novel anti-inflammatory.

scientific article

Alpha-methylacyl-CoA racemase deletion has mutually counteracting effects on T-cell responses, associated with unchanged course of EAE.

scientific article published on 9 December 2015

Alteration of granuloma formation by PGE1: effects of an adenylate cyclase inhibitor and splenectomy

scientific article published on 01 January 1980

Alterations in Granulation Tissue Growth Induced <i>in vivo</i> by Lymphocytes from Adjuvant-Diseased Rats ⬇️

scientific article published on January 1, 1979

Alterations in prostaglandin E1-induced blood flow changes in granulation tissue [proceedings] ⬇️

scientific article published on May 1, 1979

An in vitro test system for compounds that modulate human inflammatory macrophage polarization

scientific article published on 18 June 2018

Anti-inflammatory activity of azithromycin attenuates the effects of lipopolysaccharide administration in mice

scientific article published on 06 April 2006

Antibiotic therapy for exacerbations of chronic obstructive pulmonary disease (COPD).

scientific article published on October 2010

Antibiotics for asthma?

scientific article published on 01 January 2004

Antioxidant and anti-inflammatory activities of selenomethylene blue.

scientific article published in January 1993

Azithromycin and clarithromycin inhibit lipopolysaccharide-induced murine pulmonary neutrophilia mainly through effects on macrophage-derived granulocyte-macrophage colony-stimulating factor and interleukin-1beta.

scientific article

Azithromycin distinctively modulates classical activation of human monocytes in vitro.

scientific article published on March 2012

Azithromycin drives in vitro GM-CSF/IL-4-induced differentiation of human blood monocytes toward dendritic-like cells with regulatory properties

scientific article published on 30 November 2011

Azithromycin modulates neutrophil function and circulating inflammatory mediators in healthy human subjects.

scientific article

Azithromycin: mechanisms of action and their relevance for clinical applications.

scientific article published on 11 March 2014

Benefit-risk assessment of the squeezed sap of the purple coneflower (Echinacea purpurea) for long-term oral immunostimulation.

scientific article published on May 1996

COX-2 inhibitors at the 8th International Conference of the Inflammation Research Association

scientific article published on 01 January 1997

Cellular uptake and efflux of azithromycin, erythromycin, clarithromycin, telithromycin, and cethromycin

scientific article

Ceramides as Novel Disease Biomarkers

scientific article published on 23 November 2018

Chemiluminescence from mouse resident macrophages: characterization and modulation by arachidonate metabolites

scientific article published on 01 April 1983

Collagen metabolism and phenotype after prostaglandin E2 treatment of granuloma: direct and macrophage-modulated effects

scientific article published on 01 January 1982

Combination of theophylline and prostaglandin E1 as inhibitors of the adjuvant-induced arthritis syndrome of rats ⬇️

scientific article published on June 1, 1978

Comparison of pulmonary inflammatory and antioxidant responses to intranasal live and heat-killed Streptococcus pneumoniae in mice

scientific article published on 01 October 2011

Comparison of the effects of inhibitors of cytochrome P-450-mediated reactions on human platelet aggregation and arachidonic acid metabolism

scientific article published on 01 October 1981

Complement-dependent stimulation of prostacyclin biosynthesis: inhibition by rosmarinic acid

scientific article published on 01 April 1986

Cyclic AMP and prostaglandin E in perfusates of rat hind paws during the development of adjuvant arthritis ⬇️

scientific article published on June 1, 1978

Cyclic AMP in macrophages from experimental granulomas and the effect of prostaglandin E2

scientific article published on 01 December 1980

Cyclosporin: an IL8-binding protein

scientific article published on 01 September 1993

Determinants of inflammation test selection: in vitro or in vivo?

scientific article published on 01 January 1986

Development of enhanced blood flow responses to prostaglandin E1 in carrageenan-induced granulation tissue

scientific article published on 01 December 1979

Dietary phytol reduces clinical symptoms in experimental autoimmune encephalomyelitis (EAE) at least partially by modulating NOX2 expression

article

Differential evaluation of excisional non-occluded wound healing in db/db mice

scientific article published on 30 January 2009

Distinction between prostaglandin E2 and prostacyclin as inhibitors of granulomatous inflammation ⬇️

scientific article published on August 1, 1979

Distinction between responsiveness of macrophages to cyclic-AMP elevation by prostaglandin E2 and prostacyclin

scientific article published on 01 January 1981

Distribution and Further Studies on the Activity of Prostaglandin E in Chronic Granulomatous Inflammation ⬇️

scientific article published on January 1, 1979

Drug Release and Targeting: the Versatility of Polymethacrylate Nanoparticles for Peroral Administration Revealed by Using an Optimized In Vitro-Toolbox.

scientific article published on 28 July 2015

Drug Repurposing for the Development of Novel Analgesics.

scientific article published on 16 December 2015

Drugging the pain epigenome.

scientific article published on 26 May 2017

Dysregulation of lysophosphatidic acids in multiple sclerosis and autoimmune encephalomyelitis.

scientific article

Ebselen: a new approach to the inhibition of peroxide-dependent inflammation

scientific article published on 01 January 1987

Effects of 2-aminomethyl-4-t-butyl-6-iodophenol (MK-447) on granulomatous inflammation: lack of correlation with changes in levels of prostaglandin-like material

scientific article published on 01 August 1979

Effects of prostaglandin E1 on T cell function in vivo

scientific article published on 01 January 1980

Enhancement by PL 14736 of granulation and collagen organization in healing wounds and the potential role of egr-1 expression

scientific article published on 16 June 2007

Enhancement by prostaglandin E1 and essential fatty acid deficiency of the passive transfer of delayed hypersensitivity to PPD in rats. Comparison with effects on delayed hypersensitivity to SRBC in mice

scientific article published on 01 January 1979

Experimental conditions determine effects of ascorbic acid on reperfusion injury: comparison of tissue damage with hemodynamic parameters in rat isolated hearts

scientific article published on 01 July 1992

Flow cytometry-based FRET identifies binding intensities in PPARγ1 protein-protein interactions in living cells

scientific article published on 28 July 2019

High-Throughput Analysis of Global DNA Methylation Using Methyl-Sensitive Digestion

scientific article

Highlights of the joint 14th European Workshop on Inflammation and British Inflammation Research Association meeting, London, July 1-3, 1992

scientific article published on 01 January 1993

IL-38 Ameliorates Skin Inflammation and Limits IL-17 Production from γδ T Cells

scientific article published on 01 April 2019

Immune enhancement of granuloma formation as an experimental model for the pannus of rheumatoid arthritis ⬇️

scientific article published on 01 December 1980

Immunogenicity assay development and validation for biological therapy as exemplified by ustekinumab

scientific article published on 03 February 2019

Immunomodulatory effects of antimicrobials in the therapy of respiratory tract infections.

scientific article

Immunomodulatory-antiinflammatory functions of E-type prostaglandins. Minireview with emphasis on macrophage-mediated effects.

scientific article published on January 1982

Improving target assessment in biomedical research: the GOT-IT recommendations

scientific article published on 16 November 2020

In Vitro Safety, Off-Target and Bioavailability Profile of the Antiviral Compound Silvestrol

scientific article published in 2022

Increased collagen metabolism in granulomata induced in rats deficient in endogenous prostaglandin precursors

scientific article published on 01 October 1977

Induction of Experimental Autoimmune Encephalomyelitis in Mice and Evaluation of the Disease-dependent Distribution of Immune Cells in Various Tissues.

scientific article

Inflammation 2005 - Seventh World Congress. Rheumatoid arthritis and cell signaling

article

Inflammation Research: modern design, more quality science ⬇️

scientific article published on 01 January 2011

Inflammation symptoms and signalling.

scientific article

Inflammation: from molecular biology to clinic.

scientific article published on February 1998

Inflammatory models in rats depleted of endogenous precursors of prostaglandins

scientific article published on 01 January 1978

Inverted Perceptual Judgment of Nociceptive Stimuli at Threshold Level following Inconsistent Cues

scientific article

Is there a COX-fight during inflammation?

scientific article published on 01 February 1998

Joint international meeting: 3rd meeting on side effects of anti-inflammatory drugs and 13th European Workshop on Inflammation 8-11 May, 1991. Verona, Italy

scientific article published on January 1, 1992

Journal status and new developments ⬇️

scientific article published on January 1, 2013

Kadsurenone distinguishes between different platelet activating factor receptor subtypes on macrophages and polymorphonuclear leucocytes.

scientific article published on February 1986

Kinetic characterization of selective peroxisome-proliferator-activated receptor gamma modulators in vitro.

scientific article

Macrolide antibiotics broadly and distinctively inhibit cytokine and chemokine production by COPD sputum cells in vitro

scientific article published on 17 February 2011

Macrolides for the treatment of chronic bacterial prostatitis: an effective application of their unique pharmacokinetic and pharmacodynamic profile (Review).

scientific article published on 25 August 2011

Macrophage regulation of collagen deposition in granuloma tissue in vivo and the effect of prostaglandin E2

scientific article published on 01 January 1981

Macrophage, lymphocyte and chronic inflammatory responses in selenium deficient rodents. Association with decreased glutathione peroxidase activity

scientific article published on 01 January 1983

Macrophages as targets of inhibitory effects of E-type prostaglandins in immune-related inflammation

scientific article published on 01 December 1981

Macrophages from different sources, their production of chemiluminescence under various stimuli and the effects of PGE2 and drugs

scientific article published on 01 December 1981

Meeting report: environmental pollution and allergy

scientific article published on 01 August 1994

Michael acceptor containing drugs are a novel class of 5-lipoxygenase inhibitor targeting the surface cysteines C416 and C418.

scientific article

Mimickry of anti-granuloma effect of prostaglandin E by dibutyryl cyclic-AMP and some phosphodiesterase inhibitors

scientific article published on January 1, 1979

Modulation of granulomatous inflammation by prostaglandin E. Involvement of mononuclear cells

scientific article published on January 1, 1979

Modulation of neutrophil and inflammation markers in chronic obstructive pulmonary disease by short-term azithromycin treatment.

scientific article published in July 2005

Multiple rodent models and behavioral measures reveal unexpected responses to FTY720 and DMF in experimental autoimmune encephalomyelitis.

scientific article published on 12 December 2015

Mutual inversion of flurbiprofen enantiomers in various rat and mouse strains

scientific article

Nanocarriers for photodynamic therapy-rational formulation design and medium-scale manufacture

scientific article published on 26 June 2015

Natural antiviral compound silvestrol modulates human monocyte-derived macrophages and dendritic cells

scientific article published on 06 May 2020

Non-invasive bioluminescence imaging as a standardized assessment measure in mouse models of dermal inflammation

scientific article published on 23 April 2018

Novel Approaches to Persistent Pain Therapy

scientific article published on 08 May 2019

Novel antiinflammatory flavonoids from Podophyllum versipelle cell culture

scientific article published on 01 December 1986

Omega-[(omega-arylalkyl)aryl]alkanoic acids: a new class of specific LTA4 hydrolase inhibitors

scientific article published on 01 August 1992

Optimizing novel implant formulations for the prolonged release of biopharmaceuticals using in vitro and in vivo imaging techniques

scientific article published on 8 June 2016

Oxaceprol is a well-tolerated therapy for osteoarthritis with efficacy equivalent to diclofenac.

scientific article

Oxaceprol, an atypical inhibitor of inflammation and joint damage

scientific article published on 01 June 1996

Pharmacological plasticity-How do you hit a moving target?

scientific article published on 21 November 2019

Platelet activating factor (PAF) induces the oxidative burst in macrophages

scientific article published on 01 January 1983

Potential biomarkers for persistent and neuropathic pain therapy

scientific article published on 10 February 2019

Predictive PBPK modeling as a tool in the formulation of the drug candidate TMP-001

scientific article published on 16 November 2018

Progress does not just come in giant leaps: adapting techniques for the study of inflammation to novel applications.

scientific article published on 28 September 2016

Prostaglandin E2 elevation of cyclic-AMP in granuloma macrophages at various stages of inflammation: relevance to anti-inflammatory and immunomodulatory functions

scientific article published on 01 July 1981

Prostaglandins and granuloma formation in vivo

scientific article published on January 1, 1979

Prostaglandins, essential fatty acids and cell-tissue interactions in immune-inflammation

scientific article published on 01 January 1981

R-flurbiprofen attenuates experimental autoimmune encephalomyelitis in mice

scientific article

Reduced exudation and increased tissue proliferation during chronic inflammation in rats deprived of endogenous prostaglandin precursors

scientific article published on August 1, 1977

Regulation of the macrophage oxidative burst by mediators: effects of inhibitors.

scientific article published in March 1985

Regulation of the oxidative burst of macrophages by lipid mediators

scientific article published on 01 January 1984

Selective inhibition of leukotriene B4 formation by Ebselen: a novel approach to antiinflammatory therapy

scientific article published on 01 January 1986

Seleno-organic compounds and the therapy of hydroperoxide-linked pathological conditions.

scientific article published on October 1987

Sodium cromoglycate and nedocromil sodium in the therapy of asthma, a critical comparison.

scientific article published on April 1996

Stimulating brain recovery after stroke using theranostic albumin nanocarriers loaded with nerve growth factor in combination therapy

scientific article published on 17 November 2018

Stimulation of the oxidative burst in macrophages with platelet activating factor (PAF-acether)

scientific article published on 01 January 1982

Structural and functional properties of heat-shock proteins in inflammation and immunity. European workshop on inflammation. Airport meeting, March 15, 1991. Frankfurt airport, Germany

scientific article published on January 1, 1992

Structure optimization of a new class of PPARγ antagonists

scientific article published on 27 August 2019

THP-1 and human peripheral blood mononuclear cell-derived macrophages differ in their capacity to polarize in vitro.

scientific article published on 07 June 2017

Targeting CYP2J to reduce paclitaxel-induced peripheral neuropathic pain.

scientific article published on 17 October 2016

The early research and development of ebselen

scientific article

The effect of metyrapone on granuloma induced by carrageenan-impregnated sponges in normal and essential fatty acid deficient rats

scientific article published on November 1, 1977

The enigma of ceramide synthase regulation in mammalian cells

scientific article published on 13 May 2016

The inflammatory response to lymph node cells from adjuvant-diseased rats. Relative contributions of donor and recipient cell populations

scientific article published on 01 April 1980

The inflammatory response to lymph node cells from adjuvant-diseased rats: late changes in local and systemic leucocyte counts in the Wistar strain

scientific article published on 01 September 1980

The novel antifungal agent PLD-118 is neither metabolized by liver microsomes nor inhibits cytochrome P450 in vitro.

scientific article published in January 2005

The pharmacology of antirheumatic drugs.

scientific article published on January 1984

The relevance of ceramides and their synthesizing enzymes for multiple sclerosis

scientific article published on 17 August 2018

The selective protection afforded by ebselen against lipid peroxidation in an ROS-dependent model of inflammation

scientific article published on 01 May 1992

The serum amyloid A response to sterile silver nitrate in mice and its inhibition by dexamethasone and macrolide antibiotics.

scientific article published on 30 August 2007

The use of essential fatty acid deficient rats to study pathophysiological roles of prostaglandins. Comparison of prostaglandin production with some parameters of deficiency ⬇️

scientific article published on April 1, 1979

Time-dependent pro- and anti- inflammatory effects of prostaglandin (PG)E1 on experimental granulomata rats [proceedings] ⬇️

scientific article published on March 1, 1978

Time-dependent stimulatory and inhibitory effects of prostaglandin E1 on exudative and tissue components of granulomatous inflammation in rats ⬇️

scientific article published on March 1, 1979

Tolerizing CTL by Sustained Hepatic PD-L1 Expression Provides a New Therapy Approach in Mouse Sepsis

scientific article published on 16 March 2019

Topical azithromycin and clarithromycin inhibit acute and chronic skin inflammation in sensitized mice, with apparent selectivity for Th2-mediated processes in delayed-type hypersensitivity

scientific article published on 01 February 2012

Paulina is supported by:

About Paulina

Help