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List of works by Karl Kieburtz

"It is not guaranteed that you will benefit": True but misleading?

scientific article published on 11 May 2015

A longitudinal program for biomarker development in Parkinson's disease: a feasibility study

scientific article published in October 2009

A phase 3 trial of semagacestat for treatment of Alzheimer's disease

scientific article published on July 2013

A practical approach to remote longitudinal follow-up of Parkinson's disease: the FOUND study

scientific article published on 11 February 2014

A randomized controlled trial of etilevodopa in patients with Parkinson disease who have motor fluctuations

scientific article published in February 2006

A randomized trial of a low-dose Rasagiline and Pramipexole combination (P2B001) in early Parkinson's disease.

scientific article published on 3 April 2017

A randomized, double-blind, placebo-controlled trial of coenzyme Q10 in Huntington disease

scientific article published on 02 December 2016

A randomized, placebo-controlled trial of latrepirdine in Huntington disease

scientific article

A randomized, placebo-controlled trial of oxycodone and of gabapentin for acute pain in herpes zoster

scientific article published on 04 February 2009

A responsive outcome for Parkinson's disease neuroprotection futility studies

scientific article

A review of disease progression models of Parkinson's disease and applications in clinical trials

scientific article published on 26 May 2016

ADAGIO misses a beat?

scientific article published in December 2009

Advances in clinical trials for movement disorders

scientific article published on 26 August 2015

Advocacy Recruiting for Huntington’s Disease Clinical Trials ⬇️

scientific article published on April 12, 2011

An approach to evaluating the therapeutic misconception

scientific article

Appointing a proxy for research consent after one develops dementia: the need for further study

scientific article published in May 2006

Are patients with amyotrophic lateral sclerosis at risk of a therapeutic misconception?

scientific article published on 10 March 2016

Are therapeutic motivation and having one's own doctor as researcher sources of therapeutic misconception?

scientific article

Association of cerebrospinal fluid β-amyloid 1-42, T-tau, P-tau181, and α-synuclein levels with clinical features of drug-naive patients with early Parkinson disease

scientific article

Attenuated central nervous system infection in advanced HIV/AIDS with combination antiretroviral therapy

scientific article published in November 2004

Baseline prevalence and longitudinal evolution of non-motor symptoms in early Parkinson's disease: the PPMI cohort

scientific article published on 6 October 2017

Beyond disgust: impaired recognition of negative emotions prior to diagnosis in Huntington's disease

scientific article

Biomarker-driven phenotyping in Parkinson's disease: A translational missing link in disease-modifying clinical trials

scientific article published on 24 February 2017

Building Capacity Across the Spectrum of Research Translation: Centers of Excellence within the Rochester Clinical and Translational Science Institute ⬇️

scientific article published on December 1, 2010

CSF biomarkers associated with disease heterogeneity in early Parkinson's disease: the Parkinson's Progression Markers Initiative study

scientific article published on 28 March 2016

CTSA Consortium Consensus Scientific Review Committee (SRC) Working Group Report on the SRC Processes

scientific article

Cancer incidence in a trial of an antiapoptotic agent for Parkinson's disease

scientific article published in September 2010

Clinical and Dopamine Transporter Imaging Characteristics of Leucine- Rich Repeat Kinase 2 (LRRK2) and Glucosylceramidase Beta (GBA) Parkinson's Disease Participants in the Parkinson's Progression Markers Initiative: A Cross-Sectional Study

scientific article published on 19 February 2020

Clinical-Genetic Associations in the Prospective Huntington at Risk Observational Study (PHAROS): Implications for Clinical Trials

scientific article

Comparison of enrollees and decliners of Parkinson disease sham surgery trials ⬇️

scientific article published on February 7, 2012

Continuous intrajejunal infusion of levodopa-carbidopa intestinal gel for patients with advanced Parkinson's disease: a randomised, controlled, double-blind, double-dummy study

scientific article

Core assessment program for intracerebral transplantation in Huntington's disease (CAPIT-HD)

Could the High Prevalence of Therapeutic Misconception Partly Be a Measurement Problem?

scientific article published on July 2015

Defining disease‐modifying therapies for PD—A road map for moving forward ⬇️

scientific article published on September 15, 2010

Design considerations for a multicenter randomized controlled trial of early surgery for mesial temporal lobe epilepsy

scientific article

Designing clinical trials for dystonia

scientific article published on January 2014

Designing neuroprotection trials in Parkinson's disease

scientific article

Disease progression and pharmacodynamics in Parkinson disease - evidence for functional protection with levodopa and other treatments

scientific article published on 20 April 2006

Early surgical therapy for drug-resistant temporal lobe epilepsy: a randomized trial.

scientific article

Education and training of clinical and translational study investigators and research coordinators: A competency-based approach

Effect of L-methionine on hot flashes in postmenopausal women: a randomized controlled trial

scientific article published on September 2009

Effect of creatine monohydrate on clinical progression in patients with Parkinson disease: a randomized clinical trial

scientific article

Effects of L-isoleucine and L-valine on hot flushes and serum homocysteine: a randomized controlled trial

scientific article published on July 2008

Effects of coenzyme Q10 in early Parkinson disease: evidence of slowing of the functional decline

scientific article

Ethics of sham surgery: perspective of patients

scientific article published on January 2008

Evidence-based research ethics and determinations of "engagement in research"

scientific article published on March 2014

Factors predictive of the development of Levodopa-induced dyskinesia and wearing-off in Parkinson's disease

scientific article published on 29 April 2013

Gabapentin's effects on hot flashes in postmenopausal women: a randomized controlled trial

scientific article

Gene delivery of AAV2-neurturin for Parkinson's disease: a double-blind, randomised, controlled trial

scientific article

Huntington's disease: Current and future therapeutic prospects

scientific article published on 08 May 2018

Impact of sustained deprenyl (selegiline) in levodopa-treated Parkinson's disease: a randomized placebo-controlled extension of the deprenyl and tocopherol antioxidative therapy of parkinsonism trial

scientific article

Increased levels of total tau protein in the cerebrospinal fluid in Huntington's disease

scientific article

Initiating levodopa/carbidopa therapy with and without entacapone in early Parkinson disease: the STRIDE-PD study

scientific article published in July 2010

Interrater agreement in the assessment of motor manifestations of Huntington's disease

scientific article published in March 2005

Levels of the light subunit of neurofilament triplet protein in cerebrospinal fluid in Huntington's disease

scientific article published on 4 December 2008

Levodopa and the progression of Parkinson's disease

scientific article

Long term understanding of study information in research participants with Parkinson's disease

scientific article

Longer Duration of MAO-B Inhibitor Exposure is Associated with Less Clinical Decline in Parkinson's Disease: An Analysis of NET-PD LS1.

scientific article

Longitudinal change of clinical and biological measures in early Parkinson's disease: Parkinson's progression markers initiative cohort

scientific article published on 23 March 2018

Malignant melanoma in early-treated Parkinson's disease: the NET-PD trial

scientific article

Milestones in movement disorders clinical trials: Advances and landmark studies ⬇️

scientific article published on May 1, 2011

Moving Parkinson care to the home

scientific article published on 8 August 2016

New drugs for Parkinson's disease: The regulatory and clinical development pathways in the United States

scientific article published on 4 December 2017

Non-linearity of Parkinson's disease progression: implications for sample size calculations in clinical trials

scientific article published in January 2005

Novel methods and technologies for 21st-century clinical trials: a review

scientific article

Oral repeated-dose toxicity studies of coenzyme Q10 in beagle dogs

scientific article published on 20 January 2012

Parkinson's disease: Evidence for environmental risk factors ⬇️

scientific article published on October 24, 2012

Pharmacologic approaches to the treatment of Huntington's disease

scientific article published on October 13, 2011

Phase 3 trials of solanezumab for mild-to-moderate Alzheimer's disease

scientific article published in January 2014

Pivotal studies of orphan drugs approved for neurological diseases

scientific article published on August 2009

Pramipexole vs levodopa as initial treatment for Parkinson disease: a 4-year randomized controlled trial

scientific article

Preparing for preventive clinical trials: the Predict-HD study

scientific article published in June 2006

Rasagiline improves quality of life in patients with early Parkinson's disease

scientific article published in May 2006

Research participants' "irrational" expectations: common or commonly mismeasured?

scientific article published on January 1, 2013

Results of the citalopram to enhance cognition in Huntington disease trial

scientific article published on 27 December 2013

Safety and Exploratory Efficacy at 36 Months in Open-HART, an Open-Label Extension Study of Pridopidine in Huntington's Disease

scientific article published on 12 August 2017

Safety and tolerability of high-dosage coenzyme Q10 in Huntington's disease and healthy subjects

scientific article

Science and ethics of sham surgery: a survey of Parkinson disease clinical researchers

scientific article

Serum urate as a predictor of clinical and radiographic progression in Parkinson disease

scientific article

TCH346 as a neuroprotective drug in Parkinson's disease: a double-blind, randomised, controlled trial

scientific article

TRACK-HD: both promise and disappointment ⬇️

scientific article published on December 2, 2011

Test-retest reliability of the unified Parkinson's disease rating scale in patients with early Parkinson's disease: results from a multicenter clinical trial

scientific article

The Parkinson's progression markers initiative (PPMI) - establishing a PD biomarker cohort

scientific article published on 31 October 2018

The idiopathic intracranial hypertension treatment trial: design considerations and methods

scientific article published in June 2014

The relationship between CAG repeat length and clinical progression in Huntington's disease

scientific article published in July 2008

The relationship between uric acid levels and Huntington's disease progression

scientific article

Therapeutic development paths for cognitive impairment in Parkinson's disease: report of a regulatory roundtable

scientific article

Therapeutic strategies to prevent motor complications in Parkinson's disease

scientific article published on August 2008

Toward more efficient clinical trials for amyotrophic lateral sclerosis

scientific article published on May 2010

Translational experimental therapeutics: The translation of laboratory-based discovery into disease-related therapy

scientific article published on April 2007

Trust in early phase research: therapeutic optimism and protective pessimism

scientific article published on 16 July 2008

Understanding the 'therapeutic misconception' from the research participant's perspective

scientific article published on 4 May 2016

Urate as a predictor of the rate of clinical decline in Parkinson disease

scientific article

Using global statistical tests in long-term Parkinson's disease clinical trials

scientific article

Verbal episodic memory declines prior to diagnosis in Huntington's disease

scientific article published on 09 January 2007

Welding and Parkinson disease: is there a bond?

scientific article published in June 2005

What is the risk of sham surgery in Parkinson disease clinical trials? A review of published reports

scientific article

Why hasn't neuroprotection worked in Parkinson's disease?

scientific article published on May 2007

Why have we failed to achieve neuroprotection in Parkinson's disease?

scientific article published on December 2008

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