Search filters

List of works by Charles Warren Olanow

A changing journal for a changing field

scientific article

A double-blind controlled trial of bilateral fetal nigral transplantation in Parkinson's disease

scientific article published in September 2003

A double-blind, delayed-start trial of rasagiline in Parkinson's disease

scientific article

A double-blind, delayed-start trial of rasagiline in Parkinson's disease (the ADAGIO study): prespecified and post-hoc analyses of the need for additional therapies, changes in UPDRS scores, and non-motor outcomes

scientific article

A model-based approach for assessing parkinsonian gait and effects of levodopa and deep brain stimulation

scientific article

A randomized trial of a low-dose Rasagiline and Pramipexole combination (P2B001) in early Parkinson's disease.

scientific article published on 3 April 2017

A randomized, double-blind, placebo-controlled, delayed start study to assess rasagiline as a disease modifying therapy in Parkinson's disease (the ADAGIO study): rationale, design, and baseline characteristics

scientific article

A rationale for dopamine agonists as primary therapy for Parkinson's disease

scientific article (publication date: February 1992)

Abolishing the 1-year rule: How much evidence will be enough?

scientific article published on 26 September 2016

Activation of phosphoinositide 3-kinase by D2 receptor prevents apoptosis in dopaminergic cell lines

scientific article published on July 2003

Advances in clinical trials for movement disorders

scientific article published on 26 August 2015

Adverse event reporting in clinical trials in Parkinson's Disease: Time for change

scientific article published on 01 November 2018

Aggresome-related biogenesis of Lewy bodies

scientific article published in December 2002

Alterations in lysosomal and proteasomal markers in Parkinson's disease: relationship to alpha-synuclein inclusions

scientific article

Altered proteasomal function in sporadic Parkinson's disease

scientific article

Apoptosis in neurodegenerative diseases: the role of mitochondria

scientific article

Assessment of sleepiness and unintended sleep in Parkinson's disease patients taking dopamine agonists ⬇️

scientific article published on July 1, 2003

Attempts to obtain neuroprotection in Parkinson's disease ⬇️

scientific article published on July 1, 1997

Bioactivity of AAV2‐neurturin gene therapy (CERE‐120): Differences between Parkinson's disease and nonhuman primate brains ⬇️

scientific article published on November 18, 2010

Brain magnetic resonance imaging in multiple-system atrophy and Parkinson disease: a diagnostic algorithm

scientific article published in May 2002

Brainstem pathology in DYT1 primary torsion dystonia

scientific article published in October 2004

COMT inhibitors in Parkinson's disease: can they prevent and/or reverse levodopa-induced motor complications?

scientific article published on January 2004

Can we achieve neuroprotection with currently available anti-parkinsonian interventions?

scientific article published on February 2009

Changing the research criteria for the diagnosis of Parkinson's disease: obstacles and opportunities

scientific article

Clinical approaches to the development of a neuroprotective therapy for PD.

scientific article

Clinical diagnostic criteria for dementia associated with Parkinson's disease

scientific article published on September 2007

Clinical pattern and risk factors for dyskinesias following fetal nigral transplantation in Parkinson's disease: a double blind video-based analysis

scientific article published in February 2009

Clinical usefulness of the Parkinson's disease sleep scale

scientific article published in August 2005

Continuing efforts to obtain continuous delivery of levodopa ⬇️

scientific article published on 01 October 2011

Continuous administration of rotigotine to MPTP-treated common marmosets enhances anti-parkinsonian activity and reduces dyskinesia induction.

scientific article published on 18 July 2009

Continuous dopamine-receptor treatment of Parkinson's disease: scientific rationale and clinical implications

scientific article published on August 2006

Continuous dopaminergic stimulation in early and advanced Parkinson's disease

scientific article published on January 2004

Continuous intrajejunal infusion of levodopa-carbidopa intestinal gel for patients with advanced Parkinson's disease: a randomised, controlled, double-blind, double-dummy study

scientific article

DLB and PDD boundary issues: diagnosis, treatment, molecular pathology, and biomarkers

scientific article published on March 2007

Deep brain stimulation for Parkinson's disease: thinking about the long-term in the short-term

scientific article published on 01 November 2011

Deep-brain stimulation of the subthalamic nucleus or the pars interna of the globus pallidus in Parkinson's disease

scientific article

Defining disease‐modifying therapies for PD—A road map for moving forward ⬇️

scientific article published on September 15, 2010

Depression and benign intracranial hypertension

scientific article published in May 1985

Diagnostic procedures for Parkinson's disease dementia: recommendations from the movement disorder society task force

scientific article published on December 2007

Differential modulation of Akt/glycogen synthase kinase-3beta pathway regulates apoptotic and cytoprotective signaling responses

scientific article published on 3 April 2008

Differential role of dopamine in emotional attention and memory: Evidence from Parkinson's disease ⬇️

scientific article published on June 2, 2011

Disease duration and the integrity of the nigrostriatal system in Parkinson's disease

scientific article published on August 2013

Do subjects with minimal motor features have prodromal PD?

scientific article published on 8 February 2018

Dopaminergic neurons degenerate by apoptosis in Parkinson's disease.

scientific article published in March 1999

Dopaminergic transplantation for Parkinson's disease: current status and future prospects

scientific article

Dopaminergic transplants in patients with Parkinson's disease: neuroanatomical correlates of clinical recovery

scientific article published on March 1997

Double-blind, placebo-controlled study of entacapone in levodopa-treated patients with stable Parkinson disease

scientific article published in October 2004

Double-blind, randomized, controlled trial of rasagiline as monotherapy in early Parkinson's disease patients

scientific article

Drug insight: Continuous dopaminergic stimulation in the treatment of Parkinson's disease

scientific article published on July 2006

Drug selection and timing of initiation of treatment in early Parkinson's disease

scientific article

Early single cell bifurcation of pro- and antiapoptotic states during oxidative stress

scientific article published on 12 April 2004

Effects of levodopa on cognitive functioning in moderate-to-severe Parkinson's disease (MSPD).

scientific article published on 12 May 2004

Eldad Melamed 1942-2015: Ave atque--A memorial

scientific article published on 18 December 2015

Emotional processing affects movement speed ⬇️

scientific article published on April 26, 2011

Evidence of neuronal oxidative damage in Alzheimer's disease.

scientific article published on July 1996

Factors predictive of the development of Levodopa-induced dyskinesia and wearing-off in Parkinson's disease

scientific article published on 29 April 2013

Factors predictive of the need for levodopa therapy in early, untreated Parkinson's disease. The Parkinson Study Group

scientific article published in June 1995

Fetal grafting for Parkinson's disease: expression of immune markers in two patients with functional fetal nigral implants

scientific article published in May 1997

Fetal grafts for Parkinson's disease: Decades in the making

scientific article published on 31 May 2016

Four pioneers of L-dopa treatment: Arvid Carlsson, Oleh Hornykiewicz, George Cotzias, and Melvin Yahr

scientific article published on 08 December 2014

Frequency-velocity mismatch: a fundamental abnormality in parkinsonian gait

scientific article

Gene delivery of AAV2-neurturin for Parkinson's disease: a double-blind, randomised, controlled trial

scientific article

Gene delivery of neurturin to putamen and substantia nigra in Parkinson disease: A double-blind, randomized, controlled trial

scientific article published on 10 June 2015

Gene transfer of trophic factors and stem cell grafting as treatments for Parkinson's disease

scientific article published in May 2006

High-frequency unilateral thalamic stimulation in the treatment of essential and parkinsonian tremor.

scientific article published in September 1997

Huntington's disease: Current and future therapeutic prospects

scientific article published on 08 May 2018

Impact factor for 2013.

scientific article published in August 2014

Impact of sustained deprenyl (selegiline) in levodopa-treated Parkinson's disease: a randomized placebo-controlled extension of the deprenyl and tocopherol antioxidative therapy of parkinsonism trial

scientific article

Impairment of the ubiquitin-proteasome system causes dopaminergic cell death and inclusion body formation in ventral mesencephalic cultures

scientific article

Inhibition of proteasome activity sensitizes dopamine neurons to protein alterations and oxidative stress

scientific article published in October 2004

Initiating levodopa/carbidopa therapy with and without entacapone in early Parkinson disease: the STRIDE-PD study

scientific article published in July 2010

International multicenter pilot study of the first comprehensive self-completed nonmotor symptoms questionnaire for Parkinson's disease: the NMSQuest study.

scientific article published in July 2006

Is Parkinson's disease a prion disorder?

scientific article published on 28 July 2009

Leucine-rich repeat kinase 2 (LRRK2)/PARK8 possesses GTPase activity that is altered in familial Parkinson's disease R1441C/G mutants

scientific article published on 10 July 2007

Levodopa and the progression of Parkinson's disease

scientific article

Levodopa in the treatment of Parkinson's disease: a consensus meeting

scientific article

Levodopa in the treatment of Parkinson's disease: current controversies

scientific article published in September 2004

Levodopa is toxic to dopamine neurons in an in vitro but not an in vivo model of oxidative stress

scientific article published in February 2003

Levodopa therapy for Parkinson's disease: challenges and future prospects.

scientific article published in January 2008

Levodopa toxicity and Parkinson disease: still a need for equipoise

scientific article published on 14 September 2011

Levodopa-induced dyskinesias in the absence of nigrostriatal degeneration

scientific article published on 20 June 2013

Levodopa/dopamine replacement strategies in Parkinson's disease--future directions

scientific article published on January 2008

Levodopa: A new look at an old friend

scientific article published on 27 November 2017

Levodopa: effect on cell death and the natural history of Parkinson's disease

scientific article

Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease

scientific article

Lewy-body formation is an aggresome-related process: a hypothesis

scientific article published in August 2004

Long-term effects of rasagiline and the natural history of treated Parkinson's disease.

scientific article published in October 2016

MDS clinical diagnostic criteria for Parkinson's disease

scientific article

MDS research criteria for prodromal Parkinson's disease

scientific article

MRI and PET studies of manganese-intoxicated monkeys

scientific article published on June 1995

Manganese intoxication in the rhesus monkey: a clinical, imaging, pathologic, and biochemical study

scientific article published on February 1996

Manganism and idiopathic parkinsonism: similarities and differences

scientific article

Melvin David Yahr, MD (1917-2004).

scientific article published in June 2004

Milestones in magnetic resonance imaging and transcranial sonography of movement disorders

scientific article

Milestones in movement disorders clinical trials: Advances and landmark studies ⬇️

scientific article published on May 1, 2011

Movement Disorder Society-sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS): Process, format, and clinimetric testing plan

article

Movement Disorder Society-sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS): Scale presentation and clinimetric testing results

article

Movement disorder society criteria for clinically established early Parkinson's disease

scholarly article by Daniela Berg et al published 25 August 2018 in Movement Disorders

Movement disorders and AIDS: a review

scientific article

Movement disorders: a step in the right direction

scientific article

Multicenter, open-label, trial of sarizotan in Parkinson disease patients with levodopa-induced dyskinesias (the SPLENDID Study).

scientific article published in March 2004

Multiple small doses of levodopa plus entacapone produce continuous dopaminergic stimulation and reduce dyskinesia induction in MPTP-treated drug-naive primates

scientific article published in March 2005

Myoadenylate deaminase deficiency. Functional and metabolic abnormalities associated with disruption of the purine nucleotide cycle

scientific article

Neuroprotection for Parkinson's disease: prospects and promises

scientific article published on January 2003

Neuroprotection in Parkinson disease: mysteries, myths, and misconceptions

scientific article published on January 2004

Neuroprotection in Parkinson's disease: clinical trials

scientific article

Neuroprotective agents in Parkinson's disease: clinical evidence and caveats

scientific article published in October 2004

Neuroprotective therapy in Parkinson's disease and motor complications: a search for a pathogenesis-targeted, disease-modifying strategy

scientific article

New drugs for Parkinson's disease: The regulatory and clinical development pathways in the United States

scientific article published on 4 December 2017

Obstacles to the development of a neuroprotective therapy for Parkinson's disease

scientific article published on January 2013

Onset of dyskinesia with adjunct ropinirole prolonged-release or additional levodopa in early Parkinson's disease

scientific article published on May 2010

Open-label surgical trials for Parkinson disease: time for reconsideration

scientific article published on July 2011

Overexpression of torsinA in PC12 cells protects against toxicity.

scientific article published in February 2004

Oxidative stress and the pathogenesis of Parkinson's disease

scientific article published on December 1996

Parkinson disease: Gene therapy for Parkinson disease--a hope, or a dream?

scientific article published on 25 March 2014

Parkinson's disease and alpha synuclein: is Parkinson's disease a prion-like disorder?

scientific article published on January 2013

Parkinson's disease, proteins, and prions: milestones

scientific article published on May 2011

Parkinson's disease: unresolved issues

scientific article published in December 2008

Past, present, and future of Parkinson's disease: A special essay on the 200th Anniversary of the Shaking Palsy

scientific article published in September 2017

Placebo influences on dyskinesia in Parkinson's disease

scientific article published on April 2008

Placebo response in Parkinson's disease: comparisons among 11 trials covering medical and surgical interventions

scientific article

Post-mortem assessment of the short and long-term effects of the trophic factor neurturin in patients with α-synucleinopathies

scientific article published on 2 April 2015

Pramipexole combined with levodopa improves motor function but reduces dyskinesia in MPTP-treated common marmosets

scientific article published in February 2010

Present and future directions in the management of motor complications in patients with advanced PD ⬇️

scientific article published on September 23, 2003

Preserved emotional modulation of motor response time despite psychomotor slowing in young-old adults

scientific article published on 17 May 2011

Prevalence of movement disorders in an elderly nursing home population

scientific article published on 26 June 2007

Prevalence of nonmotor symptoms in Parkinson's disease in an international setting; study using nonmotor symptoms questionnaire in 545 patients.

scientific article published in August 2007

Preventing levodopa-induced dyskinesias

scientific article

Profile of Mahlon DeLong and Alim Benabid, 2014 Lasker-DeBakey Medical Research awardees

scientific article

Progress in clinical neurosciences: a forum on the early management of Parkinson's disease.

scientific article

Progression after chronic manganese exposure

scientific article

Progressive dementia and gait disorder in a 78 year old woman

scientific article

Prospective randomized trial of lisuride infusion versus oral levodopa in patients with Parkinson's disease

scientific article published in September 2002

Proteasomal dysfunction in sporadic Parkinson's disease

scientific article

Proteasome inhibition causes nigral degeneration with inclusion bodies in rats

scientific article published in August 2002

Protein aggregation in the pathogenesis of familial and sporadic Parkinson's disease

scientific article

Proteolytic stress: a unifying concept for the etiopathogenesis of Parkinson's disease

scientific article

Rationale for the use of dopamine agonists as neuroprotective agents in Parkinson's disease

scientific article

Regulatable promoters and gene therapy for Parkinson's disease: is the only thing to fear, fear itself?

scientific article published on 22 August 2007

Reply

Robust graft survival and normalized dopaminergic innervation do not obligate recovery in a Parkinson disease patient

scientific article

Safety and tolerability of intraputaminal delivery of CERE-120 (adeno-associated virus serotype 2-neurturin) to patients with idiopathic Parkinson's disease: an open-label, phase I trial

scientific article

Safety/feasibility of targeting the substantia nigra with AAV2-neurturin in Parkinson patients

scientific article published on 10 April 2013

Sarizotan as a treatment for dyskinesias in Parkinson's disease: a double-blind placebo-controlled trial

scientific article published on January 2007

Selective loss of 20S proteasome alpha-subunits in the substantia nigra pars compacta in Parkinson's disease

scientific article published in July 2002

Sleepiness in Parkinson's disease: a controlled study

scientific article published in June 2003

Slowing of neurodegeneration in Parkinson's disease and Huntington's disease: future therapeutic perspectives

scientific article

Stem cell treatment for Parkinson's disease: an update for 2005.

scientific article

Subthalamic deep brain stimulation and impulse control in Parkinson's disease

scientific article published in April 2009

Surgical therapy for Parkinson's disease

scientific article

Systemic exposure to proteasome inhibitors causes a progressive model of Parkinson's disease

scientific article

TCH346 as a neuroprotective drug in Parkinson's disease: a double-blind, randomised, controlled trial

scientific article

Targeting α-Synuclein as a therapy for Parkinson's disease: The battle begins.

scientific article

Targeting α-synuclein for treatment of Parkinson's disease: mechanistic and therapeutic considerations

scientific article published on 03 June 2015

Technical advances in deep brain stimulation: how far is enough?

scientific article published in March 2012

The administration of entacapone prevents L-dopa-induced dyskinesia when added to dopamine agonist therapy in MPTP-treated primates

scientific article published on 8 May 2007

The basal ganglia in Parkinson's disease: current concepts and unexplained observations

scientific article published on December 2008

The delayed-start study in Parkinson disease: can't satisfy everyone

scientific article published in April 2010

The metric properties of a novel non-motor symptoms scale for Parkinson's disease: Results from an international pilot study

scientific article published in October 2007

The neuropathology of manganese-induced Parkinsonism

scientific article

The new definition and diagnostic criteria of Parkinson's disease

scientific article published on 11 April 2016

The pathogenesis of cell death in Parkinson's disease

scientific article published on May 2006

The pathogenesis of cell death in Parkinson's disease--2007.

scientific article published on September 2007

The place of COMT inhibitors in the armamentarium of drugs for the treatment of Parkinson's disease

scientific article

The role of dopamine agonists in the treatment of early Parkinson's disease

scientific article

The scientific and clinical basis for the treatment of Parkinson disease (2009).

scientific article

The scientific basis for the current treatment of Parkinson's disease

scientific article published on January 2004

The significance of defining preclinical or prodromal Parkinson's disease ⬇️

scientific article published on April 15, 2012

The vatican meeting on neuroprotection for Parkinson's disease

scientific article

Therapeutic prospects for Parkinson disease

scientific article published on September 2013

Time to redefine PD? Introductory statement of the MDS Task Force on the definition of Parkinson's disease

scientific article

Tolcapone and hepatotoxic effects. Tasmar Advisory Panel

scientific article

Tolcapone: an efficacy and safety review (2007)

scientific article

Toxicity of glutathione depletion in mesencephalic cultures: a role for arachidonic acid and its lipoxygenase metabolites

scientific article

Tozadenant (SYN115) in patients with Parkinson's disease who have motor fluctuations on levodopa: a phase 2b, double-blind, randomised trial

scientific article published on 6 July 2014

Translating scientific advances into disease-modifying therapies for Parkinson's Disease

scientific article published in December 2017

Translational experimental therapeutics: The translation of laboratory-based discovery into disease-related therapy

scientific article published on April 2007

Transplanted dopaminergic neurons develop PD pathologic changes: a second case report

scientific article published in December 2008

Treatment of levodopa-induced motor complications

scientific article published on January 2008

Treatment with fetal allografts

scientific article published in June 1997

Trophic factors for Parkinson's disease: To live or let die.

scientific article

Ubiquitin-proteasome system and Parkinson's disease

scientific article published on November 2006

Unilateral stimulation of the subthalamic nucleus in Parkinson disease: a double-blind 12-month evaluation study

scientific article

Why delaying levodopa is a good treatment strategy in early Parkinson's disease

scientific article

Why have we failed to achieve neuroprotection in Parkinson's disease?

scientific article published on December 2008

p53 mediates nontranscriptional cell death in dopaminergic cells in response to proteasome inhibition

scientific journal article

Paulina is supported by:

About Paulina

Help