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List of works by D Allan Butterfield

3-nitropropionic acid-induced changes in bilayer fluidity in synaptosomal membranes: implications for Huntington's disease

scientific article published in June 2002

4-Hydroxy-2-nonenal, a reactive product of lipid peroxidation, and neurodegenerative diseases: a toxic combination illuminated by redox proteomics studies

scientific article published on 15 February 2012

4-Hydroxynonenal oxidatively modifies histones: implications for Alzheimer's disease

scientific article published in February 2004

A model for beta-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: relevance to Alzheimer disease

scientific article

A neuronal model of Alzheimer's disease: an insight into the mechanisms of oxidative stress-mediated mitochondrial injury

scientific article published on 7 February 2008

APP and PS-1 mutations induce brain oxidative stress independent of dietary cholesterol: implications for Alzheimer's disease

scientific article published in September 2004

Aberrant protein phosphorylation in Alzheimer disease brain disturbs pro-survival and cell death pathways

scientific article

Abeta, oxidative stress in Alzheimer disease: evidence based on proteomics studies

scientific article

Acetyl-L-carnitine-induced up-regulation of heat shock proteins protects cortical neurons against amyloid-beta peptide 1-42-mediated oxidative stress and neurotoxicity: implications for Alzheimer's disease

scientific article

Acetylcarnitine and cellular stress response: roles in nutritional redox homeostasis and regulation of longevity genes

scientific article

Acetylcarnitine induces heme oxygenase in rat astrocytes and protects against oxidative stress: involvement of the transcription factor Nrf2.

scientific article

Acrolein induces selective protein carbonylation in synaptosomes

scientific article

Acrolein inhibits NADH-linked mitochondrial enzyme activity: implications for Alzheimer's disease

scientific article published in January 2003

Acute treatment with doxorubicin affects glutamate neurotransmission in the mouse frontal cortex and hippocampus

scientific article published on 10 July 2017

Adriamycin-induced, TNF-alpha-mediated central nervous system toxicity

scientific article

Adriamycin-mediated nitration of manganese superoxide dismutase in the central nervous system: insight into the mechanism of chemobrain

scientific article

Age-related changes in the proteostasis network in the brain of the naked mole-rat: Implications promoting healthy longevity

scientific article published on 3 August 2015

Age-related loss of phospholipid asymmetry in APP(NLh)/APP(NLh) x PS-1(P264L)/PS-1(P264L) human double mutant knock-in mice: relevance to Alzheimer disease

scientific article

Alpha 1-antichymotrypsin interaction with A beta (1-42) does not inhibit fibril formation but attenuates the peptide toxicity

scientific article published in October 1996

Alteration of mTOR signaling occurs early in the progression of Alzheimer disease (AD): analysis of brain from subjects with pre-clinical AD, amnestic mild cognitive impairment and late-stage AD.

scientific article published on 26 February 2015

Alterations in brain antioxidant enzymes and redox proteomic identification of oxidized brain proteins induced by the anti-cancer drug adriamycin: implications for oxidative stress-mediated chemobrain

scientific article

Alterations of some membrane transport proteins in Alzheimer's disease: role of amyloid beta-peptide

scientific article

Alumina nanoparticles induce expression of endothelial cell adhesion molecules

scientific article published on 27 March 2008

Alzheimer's amyloid beta-peptide (1-42): involvement of methionine residue 35 in the oxidative stress and neurotoxicity properties of this peptide

scientific article published on May 2004

Amyloid β-Peptide [1-42]-Associated Free Radical-Induced Oxidative Stress And Neurodegeneration in Alzheimers Disease Brain: Mechanisms and Consequences ⬇️

scientific article published on December 1, 2003

Amyloid beta-peptide (1-40)-mediated oxidative stress in cultured hippocampal neurons. Protein carbonyl formation, CK BB expression, and the level of Cu, Zn, and Mn SOD mRNA.

scientific article published in June 1998

Amyloid beta-peptide (1-42)-induced oxidative stress and neurotoxicity: implications for neurodegeneration in Alzheimer's disease brain. A review

scientific article

Amyloid beta-peptide and amyloid pathology are central to the oxidative stress and inflammatory cascades under which Alzheimer's disease brain exists.

scientific article

Amyloid beta-peptide(1-42) contributes to the oxidative stress and neurodegeneration found in Alzheimer disease brain

scientific article

Amyloid beta-peptide-associated free radical oxidative stress, neurotoxicity, and Alzheimer's disease

scientific article

Amyloidβ-Peptide (1–42)-Induced Oxidative Stress in Alzheimer Disease: Importance in Disease Pathogenesis and Progression ⬇️

scientific article published on February 14, 2013

An increase in S-glutathionylated proteins in the Alzheimer's disease inferior parietal lobule, a proteomics approach

scientific article published in May 2007

An investigation of the molecular mechanisms engaged before and after the development of Alzheimer disease neuropathology in Down syndrome: a proteomics approach

scientific article

Annexin A1 complex mediates oxytocin vesicle transport

scientific article published on December 2013

Antioxidant activity of X-34 in synaptosomal and neuronal systems

scientific article published in October 2003

Antisense directed against PS-1 gene decreases brain oxidative markers in aged senescence accelerated mice (SAMP8) and reverses learning and memory impairment: a proteomics study

scientific article published on 15 June 2013

Antisense directed at the Abeta region of APP decreases brain oxidative markers in aged senescence accelerated mice

scientific article

Antisense oligonucleotide against GSK-3β in brain of SAMP8 mice improves learning and memory and decreases oxidative stress: Involvement of transcription factor Nrf2 and implications for Alzheimer disease

scientific article published on 16 December 2013

Apolipoprotein A-I: insights from redox proteomics for its role in neurodegeneration

scientific article

Apolipoprotein E modulates Alzheimer’s Aβ(1–42)-induced oxidative damage to synaptosomes in an allele-specific manner ⬇️

scientific article published on January 4, 2002

Association between frontal cortex oxidative damage and beta-amyloid as a function of age in Down syndrome

scientific article published on 8 October 2011

Atorvastatin and Aβ(1–40): Not as Simple as Cholesterol Reduction in Brain and Relevance to Alzheimer Disease ⬇️

scientific article published on December 28, 2010

Atorvastatin treatment in a dog preclinical model of Alzheimer's disease leads to up-regulation of haem oxygenase-1 and is associated with reduced oxidative stress in brain

scientific article published on 18 July 2011

Autoantibodies Profile in Matching CSF and Serum from AD and aMCI patients: Potential Pathogenic Role and Link to Oxidative Damage

scientific article published on 18 December 2015

Biliverdin reductase-A: a novel drug target for atorvastatin in a dog pre-clinical model of Alzheimer disease

scientific article published on 9 November 2011

Cell cycle proteins in brain in mild cognitive impairment: insights into progression to Alzheimer disease

scientific article

Chemo Brain (Chemo Fog) as a Potential Side Effect of Doxorubicin Administration: Role of Cytokine-Induced, Oxidative/Nitrosative Stress in Cognitive Dysfunction ⬇️

scientific article published on January 1, 2010

Cholesterol-independent neuroprotective and neurotoxic activities of statins: Perspectives for statin use in Alzheimer disease and other age-related neurodegenerative disorders ⬇️

scientific article published on April 22, 2011

Circulating biomarkers of protein oxidation for Alzheimer disease: expectations within limits

scientific article published on 12 October 2011

Clinical implications from proteomic studies in neurodegenerative diseases: lessons from mitochondrial proteins

scientific article published on 03 February 2016

Coenzyme Q10 and cognition in atorvastatin treated dogs

scientific article

Collateral damage in cancer chemotherapy: oxidative stress in nontargeted tissues

scientific article published on June 2007

Comparative proteomic analyses of the parietal lobe from rhesus monkeys fed a high-fat/sugar diet with and without resveratrol supplementation, relative to a healthy diet: Insights into the roles of unhealthy diets and resveratrol on function

scientific article published on 13 October 2016

Cryopreservation of rat cortical synaptosomes and analysis of glucose and glutamate transporter activities, and mitochondrial function ⬇️

scientific article published on September 1, 1998

Decreased expression and increased oxidation of plasma haptoglobin in Alzheimer disease: Insights from redox proteomics

scientific article published on 7 September 2012

Derivatives of Xanthic Acid are Novel Antioxidants: Application to Synaptosomes ⬇️

scientific article published on April 1, 2003

Detection of 4-hydroxy-2-nonenal- and 3-nitrotyrosine-modified proteins using a proteomics approach

scientific article published in January 2009

Detection of carbonylated proteins in two-dimensional sodium dodecyl sulfate polyacrylamide gel electrophoresis separations

scientific article published in January 2008

Dietary vitamin D deficiency in rats from middle to old age leads to elevated tyrosine nitration and proteomics changes in levels of key proteins in brain: Implications for low vitamin D-dependent age-related cognitive decline ⬇️

scientific article published on July 18, 2013

Differential expression and redox proteomics analyses of an Alzheimer disease transgenic mouse model: effects of the amyloid-β peptide of amyloid precursor proteinΞ ⬇️

scientific article published on January 9, 2011

Disruption of thiol homeostasis and nitrosative stress in the cerebrospinal fluid of patients with active multiple sclerosis: evidence for a protective role of acetylcarnitine

scientific article published in September 2003

Distribution, elimination, and biopersistence to 90 days of a systemically introduced 30 nm ceria-engineered nanomaterial in rats

scientific article published on 23 February 2012

Down syndrome: From development to adult life to Alzheimer disease

scientific article published on 24 October 2017

Dysregulation of cytokine mediated chemotherapy induced cognitive impairment

scientific article published on 4 January 2017

Effect of botanical extracts containing carnosic acid or rosmarinic acid on learning and memory in SAMP8 mice

scientific article published on 12 August 2016

Electron spin resonance, hematological, and deformability studies of erythrocytes from patients with Huntington's disease ⬇️

scientific article published on March 8, 1979

Elevated levels of pro-apoptotic p53 and its oxidative modification by the lipid peroxidation product, HNE, in brain from subjects with amnestic mild cognitive impairment and Alzheimer's disease

scientific article

Elevated protein-bound levels of the lipid peroxidation product, 4-hydroxy-2-nonenal, in brain from persons with mild cognitive impairment

scientific article published on 4 January 2006

Elevation of brain glutathione by gamma-glutamylcysteine ethyl ester protects against peroxynitrite-induced oxidative stress

scientific article

Elevation of glutathione as a therapeutic strategy in Alzheimer disease

scientific article published on 12 October 2011

Elevation of mitochondrial glutathione by gamma-glutamylcysteine ethyl ester protects mitochondria against peroxynitrite-induced oxidative stress

scientific article

Evidence for an increased rate of choline efflux across erythrocyte membranes in Alzheimer's disease

scientific article published in July 1985

Evidence that amyloid beta-peptide-induced lipid peroxidation and its sequelae in Alzheimer's disease brain contribute to neuronal death

scientific article

Experimental Research on Nitric Oxide and the Therapy of Alzheimer Disease: A Challenging Bridge ⬇️

scientific article published on November 1, 2011

Extracellular vesicles released by cardiomyocytes in a doxorubicin-induced cardiac injury mouse model contain protein biomarkers of early cardiac injury

scientific article

Ferulic acid ethyl ester protects neurons against amyloid beta- peptide(1-42)-induced oxidative stress and neurotoxicity: relationship to antioxidant activity

scientific article

Free radical mediated oxidative stress and toxic side effects in brain induced by the anti cancer drug adriamycin: insight into chemobrain

scientific article

Free radical oxidation of brain proteins in accelerated senescence and its modulation by N-tert-butyl-alpha-phenylnitrone

scientific article

Free radicals and brain aging

scientific article published on May 2004

Free radicals: key to brain aging and heme oxygenase as a cellular response to oxidative stress

scientific article published on May 2004

Gamma-glutamylcysteine ethyl ester protection of proteins from Abeta(1-42)-mediated oxidative stress in neuronal cell culture: a proteomics approach

scientific article published in March 2005

Gamma-glutamylcysteine ethyl ester-induced up-regulation of glutathione protects neurons against Abeta(1-42)-mediated oxidative stress and neurotoxicity: implications for Alzheimer's disease

scientific article

Global effects of adriamycin treatment on mouse splenic protein levels

scientific article published on 4 January 2012

Glutathione elevation by gamma-glutamyl cysteine ethyl ester as a potential therapeutic strategy for preventing oxidative stress in brain mediated by in vivo administration of adriamycin: Implication for chemobrain

scientific article

Glutathionylation of the Pro-apoptotic Protein p53 in Alzheimer’s Disease Brain: Implications for AD Pathogenesis

Glutathionylation of the pro-apoptotic protein p53 in Alzheimer's disease brain: implications for AD pathogenesis

scientific article

HNE-modified proteins in Down syndrome: Involvement in development of Alzheimer disease neuropathology

scientific article published on 9 November 2016

HO-1/BVR-a system analysis in plasma from probable Alzheimer's disease and mild cognitive impairment subjects: a potential biochemical marker for the prediction of the disease

scientific article published in January 2012

Heme oxygenase-1 posttranslational modifications in the brain of subjects with Alzheimer disease and mild cognitive impairment

scientific article

Identification of AGE-modified proteins in SH-SY5Y and OLN-93 cells

scientific article published on June 2006

Identification of nitrated proteins in Alzheimer's disease brain using a redox proteomics approach

scientific article published on 27 December 2005

Identification of the oxidative stress proteome in the brain ⬇️

scientific article published on November 25, 2010

In vivo administration of D609 leads to protection of subsequently isolated gerbil brain mitochondria subjected to in vitro oxidative stress induced by amyloid beta-peptide and other oxidative stressors: relevance to Alzheimer's disease and other ox

scientific article published on 8 September 2006

In vivo amelioration of adriamycin induced oxidative stress in plasma by gamma-glutamylcysteine ethyl ester (GCEE).

scientific article

In vivo oxidative stress in brain of Alzheimer disease transgenic mice: Requirement for methionine 35 in amyloid beta-peptide of APP.

scientific article published on 23 October 2009

In vivo protection by the xanthate tricyclodecan-9-yl-xanthogenate against amyloid beta-peptide (1-42)-induced oxidative stress

scientific article published on 19 January 2006

In vivo protection of synaptosomes by ferulic acid ethyl ester (FAEE) from oxidative stress mediated by 2,2-azobis(2-amidino-propane)dihydrochloride (AAPH) or Fe(2+)/H(2)O(2): insight into mechanisms of neuroprotection and relevance to oxidative str

scientific article published on 28 December 2005

In vivo protection of synaptosomes from oxidative stress mediated by Fe2+/H2O2 or 2,2-azobis-(2-amidinopropane) dihydrochloride by the glutathione mimetic tricyclodecan-9-yl-xanthogenate

scientific article

In vivo protective effects of ferulic acid ethyl ester against amyloid-beta peptide 1-42-induced oxidative stress

scientific article

Increase in Mrp1 expression and 4-hydroxy-2-nonenal adduction in heart tissue of Adriamycin-treated C57BL/6 mice

scientific article published on November 2006

Increased O-GlcNAc levels correlate with decreased O-GlcNAcase levels in Alzheimer disease brain

scientific article

Increased formation of short-chain organic acids after chronic ethanol administration and its interaction with the carnitine pool in rat.

scientific article published in November 2004

Increased protein and lipid oxidative damage in mitochondria isolated from lymphocytes from patients with Alzheimer's disease: insights into the role of oxidative stress in Alzheimer's disease and initial investigations into a potential biomarker fo

scientific article published in January 2011

Insufficient Sun Exposure Has Become a Real Public Health Problem

scientific article published on 13 July 2020

Insulin resistance in Alzheimer disease: Is heme oxygenase-1 an Achille's heel?

scientific article

Interaction of tacrine and velnacrine with neocortical synaptosomal membranes: relevance to Alzheimer's disease

scientific article published in September 1993

Intracellular human immunodeficiency virus Tat expression in astrocytes promotes astrocyte survival but induces potent neurotoxicity at distant sites via axonal transport

scientific article published on 24 January 2003

Involvement of PI3K/PKG/ERK1/2 signaling pathways in cortical neurons to trigger protection by cotreatment of acetyl-L-carnitine and alpha-lipoic acid against HNE-mediated oxidative stress and neurotoxicity: implications for Alzheimer's disease

scientific article

Involvements of the lipid peroxidation product, HNE, in the pathogenesis and progression of Alzheimer's disease

scientific article

Lack of p53 affects the expression of several brain mitochondrial proteins: insights from proteomics into important pathways regulated by p53.

scientific article

Lack of p53 decreases basal oxidative stress levels in the brain through upregulation of thioredoxin-1, biliverdin reductase-A, manganese superoxide dismutase, and nuclear factor kappa-B.

scientific article published on 21 February 2012

Lectin‐affinity chromatography brain glycoproteomics and Alzheimer disease: Insights into protein alterations consistent with the pathology and progression of this dementing disorder ⬇️

scientific article published on November 22, 2010

Lipid peroxidation and protein oxidation in Alzheimer's disease brain: potential causes and consequences involving amyloid beta-peptide-associated free radical oxidative stress

scientific article

Lipid peroxidation and tyrosine nitration in traumatic brain injury: Insights into secondary injury from redox proteomics

scientific article published on 2 September 2016

Lipid peroxidation triggers neurodegeneration: A redox proteomics view into the Alzheimer disease brain ⬇️

scientific article published on 05 October 2012

Lipopolysaccharide alters the blood-brain barrier transport of amyloid beta protein: a mechanism for inflammation in the progression of Alzheimer's disease

scientific article published on 06 February 2009

Long-term high-dose atorvastatin decreases brain oxidative and nitrosative stress in a preclinical model of Alzheimer disease: A novel mechanism of action ⬇️

scientific article published on December 27, 2010

Loss of phospholipid asymmetry and elevated brain apoptotic protein levels in subjects with amnestic mild cognitive impairment and Alzheimer disease

scientific article published on 12 November 2007

Low molecular weight thiol amides attenuate MAPK activity and protect primary neurons from Abeta(1-42) toxicity

scientific article published on 4 January 2006

Lymphocyte mitochondria: toward identification of peripheral biomarkers in the progression of Alzheimer disease

scientific article published on 08 August 2013

Mass spectrometry and redox proteomics: applications in disease

scientific article

Metabolic clues to salubrious longevity in the brain of the longest-lived rodent: the naked mole-rat

scientific article

Methionine residue 35 is critical for the oxidative stress and neurotoxic properties of Alzheimer's amyloid beta-peptide 1-42.

scientific article

Methionine-35 of Aβ(1–42): Importance for Oxidative Stress in Alzheimer Disease ⬇️

scientific article published on June 4, 2011

Mitochondrial associated metabolic proteins are selectively oxidized in A30P alpha-synuclein transgenic mice--a model of familial Parkinson's disease

scientific article

Mitochondrial dysfunction, free radical generation and cellular stress response in neurodegenerative disorders

scientific article published on January 2007

Modulation of GLP-1 signaling as a novel therapeutic approach in the treatment of Alzheimer's disease pathology

scientific article

Mrp1 localization and function in cardiac mitochondria after doxorubicin

scientific article published on 20 February 2009

Multifunctional roles of enolase in Alzheimer's disease brain: beyond altered glucose metabolism

scientific article published on 23 September 2009

Mutations in amyloid precursor protein and presenilin-1 genes increase the basal oxidative stress in murine neuronal cells and lead to increased sensitivity to oxidative stress mediated by amyloid beta-peptide (1-42), HO and kainic acid: implication

scientific journal article

Natural antioxidants in Alzheimer's disease

scientific article published on December 2007

Neurotoxicity and oxidative stress in D1M-substituted Alzheimer's A beta(1-42): relevance to N-terminal methionine chemistry in small model peptides

scientific article

Nitric oxide and cellular stress response in brain aging and neurodegenerative disorders: the role of vitagenes.

scientific article published in May 2004

Nitric oxide in the central nervous system: neuroprotection versus neurotoxicity

scientific article published on October 2007

Nitrosative stress, cellular stress response, and thiol homeostasis in patients with Alzheimer's disease

scientific article published in November 2006

Nutritional Approaches to Modulate Oxidative Stress in Alzheimers Disease ⬇️

scientific article published on August 1, 2011

Nutritional antioxidants and the heme oxygenase pathway of stress tolerance: novel targets for neuroprotection in Alzheimer's disease.

scientific article published on December 2003

Nutritional approaches to combat oxidative stress in Alzheimer's disease

scientific article

Oxidation of cytosolic proteins and expression of creatine kinase BB in frontal lobe in different neurodegenerative disorders

scientific article published in March 1999

Oxidative Modification of Brain Proteins in Alzheimer's Disease: Perspective on Future Studies Based on Results of Redox Proteomics Studies ⬇️

scientific article published on January 1, 2013

Oxidative Stress and Down Syndrome: A Route toward Alzheimer-Like Dementia ⬇️

scientific article published on November 29, 2011

Oxidative Stress and Proteostasis Network: Culprit and Casualty of Alzheimer’s-Like Neurodegeneration

Oxidative Stress, Amyloid-β Peptide, and Altered Key Molecular Pathways in the Pathogenesis and Progression of Alzheimer's Disease

scientific article published in January 2018

Oxidative damage in brain from human mutant APP/PS-1 double knock-in mice as a function of age.

scientific article published on 16 August 2008

Oxidative modification and down-regulation of Pin1 in Alzheimer's disease hippocampus: A redox proteomics analysis

scientific article published on 13 June 2005

Oxidative modification of lipoic acid by HNE in Alzheimer disease brain

scientific article published on 30 January 2013

Oxidative modification to LDL receptor-related protein 1 in hippocampus from subjects with Alzheimer disease: Implications for Aβ accumulation in AD brain ⬇️

scientific article published on October 7, 2010

Oxidative stress and therapeutic approaches in HIV dementia

scientific article published on November 2006

Oxidative stress and toxicity induced by the nucleoside reverse transcriptase inhibitor (NRTI)--2',3'-dideoxycytidine (ddC): relevance to HIV-dementia

scientific article published on 25 October 2006

Oxidative stress in Alzheimer disease and mild cognitive impairment: evidence from human data provided by redox proteomics

scientific article

Oxidative stress in Alzheimer disease: synergy between the Butterfield and Markesbery laboratories

scientific article

Oxidative stress in Alzheimer's disease brain: new insights from redox proteomics

scientific article published on 15 June 2006

Oxidative stress in HIV demented patients and protection ex vivo with novel antioxidants

scientific article

Oxidative stress in HPV-driven viral carcinogenesis: redox proteomics analysis of HPV-16 dysplastic and neoplastic tissues

scientific article

Oxidative stress in synaptosomal proteins from mutant presenilin-1 knock-in mice: implications for familial Alzheimer's disease.

scientific article

Oxidative stress in the aging murine olfactory bulb: redox proteomics and cellular localization

scientific article published in February 2007

Oxidative stress precedes fibrillar deposition of Alzheimer's disease amyloid beta-peptide (1-42) in a transgenic Caenorhabditis elegans model

scientific article published in May 2003

Oxidative stress, dysfunctional glucose metabolism and Alzheimer disease

scientific article published on 01 March 2019

Oxidative stress, mitochondrial dysfunction and cellular stress response in Friedreich's ataxia

scientific article

Oxidatively modified GST and MRP1 in Alzheimer's disease brain: implications for accumulation of reactive lipid peroxidation products

scientific article published in December 2004

Oxidatively modified glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and Alzheimer's disease: many pathways to neurodegeneration

scientific article

Oxidatively modified proteins in Alzheimer's disease (AD), mild cognitive impairment and animal models of AD: role of Abeta in pathogenesis

scientific article

Oxidatively modified, mitochondria-relevant brain proteins in subjects with Alzheimer disease and mild cognitive impairment

scientific article

Peptides and proteins in plasma and cerebrospinal fluid as biomarkers for the prediction, diagnosis, and monitoring of therapeutic efficacy of Alzheimer's disease

scientific article published on 07 August 2008

Persistent hepatic structural alterations following nanoceria vascular infusion in the rat.

scientific article published on 31 October 2013

Perspectives on Oxidative Stress in Alzheimer's Disease and Predictions of Future Research Emphases

scientific article published on 28 February 2018

Pin1 cysteine-113 oxidation inhibits its catalytic activity and cellular function in Alzheimer's disease

scientific article

Pin1 in Alzheimer's disease

scientific article published on September 2006

Potential in vivo amelioration by N-acetyl-L-cysteine of oxidative stress in brain in human double mutant APP/PS-1 knock-in mice: toward therapeutic modulation of mild cognitive impairment

scientific article published on September 2010

Preclinical Alzheimer disease: brain oxidative stress, Abeta peptide and proteomics

scientific article

Protection against amyloid beta-peptide (1–42)-induced loss of phospholipid asymmetry in synaptosomal membranes by tricyclodecan-9-xanthogenate (D609) and ferulic acid ethyl ester: Implications for Alzheimer's disease

scientific article (publication date: June 2005)

Protective effect of D609 against amyloid-beta1-42-induced oxidative modification of neuronal proteins: redox proteomics study

scientific article published in August 2006

Protective effect of quercetin in primary neurons against Abeta(1-42): relevance to Alzheimer's disease

scientific article published on 7 July 2008

Protective effect of the xanthate, D609, on Alzheimer's amyloid beta-peptide (1-42)-induced oxidative stress in primary neuronal cells

scientific article

Protein levels and activity of some antioxidant enzymes in hippocampus of subjects with amnestic mild cognitive impairment

scientific article published on 6 March 2008

Protein levels of heat shock proteins 27, 32, 60, 70, 90 and thioredoxin-1 in amnestic mild cognitive impairment: an investigation on the role of cellular stress response in the progression of Alzheimer disease

scientific article

Protein oxidation and lipid peroxidation in brain of subjects with Alzheimer's disease: insights into mechanism of neurodegeneration from redox proteomics

scientific article published on November 2006

Proteomic analysis of 4-hydroxy-2-nonenal-modified proteins in G93A-SOD1 transgenic mice--a model of familial amyotrophic lateral sclerosis

scientific article

Proteomic analysis of brain protein expression levels in NF-kappabeta p50 -/- homozygous knockout mice

scientific article published on 12 September 2008

Proteomic analysis of brain proteins in APP/PS-1 human double mutant knock-in mice with increasing amyloid β-peptide deposition: insights into the effects of in vivo treatment with N-acetylcysteine as a potential therapeutic intervention in mild cog

scientific article published on September 22, 2011

Proteomic analysis of brain proteins in the gracile axonal dystrophy (gad) mouse, a syndrome that emanates from dysfunctional ubiquitin carboxyl-terminal hydrolase L-1, reveals oxidation of key proteins.

scientific article published in March 2004

Proteomic analysis of oxidatively modified proteins induced by the mitochondrial toxin 3-nitropropionic acid in human astrocytes expressing the HIV protein tat.

scientific article

Proteomic analysis of protein expression and oxidative modification in r6/2 transgenic mice: a model of Huntington disease

scientific article published on 20 June 2005

Proteomic analysis of specific brain proteins in aged SAMP8 mice treated with alpha-lipoic acid: implications for aging and age-related neurodegenerative disorders

scientific article published in January 2005

Proteomic identification of HNE-bound proteins in early Alzheimer disease: Insights into the role of lipid peroxidation in the progression of AD.

scientific article

Proteomic identification of brain proteins in the canine model of human aging following a long-term treatment with antioxidants and a program of behavioral enrichment: relevance to Alzheimer's disease ⬇️

scientific article published on 20 October 2006

Proteomic identification of differentially expressed proteins in the aging murine olfactory system and transcriptional analysis of the associated genes

scientific article

Proteomic identification of less oxidized brain proteins in aged senescence-accelerated mice following administration of antisense oligonucleotide directed at the Abeta region of amyloid precursor protein

scientific article published in July 2005

Proteomic identification of nitrated brain proteins in amnestic mild cognitive impairment: a regional study

scientific article published on July 2007

Proteomic identification of nitrated brain proteins in early Alzheimer's disease inferior parietal lobule

scientific article

Proteomic identification of nitrated brain proteins in traumatic brain-injured rats treated postinjury with gamma-glutamylcysteine ethyl ester: insights into the role of elevation of glutathione as a potential therapeutic strategy for traumatic brai

scientific article

Proteomic identification of nitrated proteins in Alzheimer's disease brain

scientific article

Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part I: creatine kinase BB, glutamine synthase, and ubiquitin carboxy-terminal hydrolase L-1.

scientific article

Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part II: dihydropyrimidinase-related protein 2, alpha-enolase and heat shock cognate 71.

scientific article published in September 2002

Proteomic identification of oxidized mitochondrial proteins following experimental traumatic brain injury

scientific article

Proteomic identification of proteins oxidized by Abeta(1-42) in synaptosomes: implications for Alzheimer's disease

scientific article published on 15 April 2005

Proteomic identification of proteins specifically oxidized by intracerebral injection of amyloid beta-peptide (1-42) into rat brain: implications for Alzheimer's disease

scientific article published in January 2005

Proteomic identification of specifically carbonylated brain proteins in APP(NLh)/APP(NLh) × PS-1(P264L)/PS-1(P264L) human double mutant knock-in mice model of Alzheimer disease as a function of age

scientific article published on 25 June 2011

Proteomics analyses of specific protein oxidation and protein expression in aged rat brain and its modulation by L-acetylcarnitine: insights into the mechanisms of action of this proposed therapeutic agent for CNS disorders associated with oxidative

scientific article published in March 2006

Proteomics analysis in Alzheimer's disease: new insights into mechanisms of neurodegeneration

scientific article published in January 2004

Proteomics analysis of human astrocytes expressing the HIV protein Tat.

scientific article published on February 2005

Proteomics analysis of the Alzheimer's disease hippocampal proteome

scientific article

Proteomics analysis provides insight into caloric restriction mediated oxidation and expression of brain proteins associated with age-related impaired cellular processes: Mitochondrial dysfunction, glutamate dysregulation and impaired protein synthe

scientific article published on 5 July 2005

Proteomics identification of carbonylated and HNE-bound brain proteins in Alzheimer's disease

scientific article published in January 2009

Proteomics identification of oxidatively modified proteins in brain

scientific article published in January 2009

Proteomics in Alzheimer's disease: insights into potential mechanisms of neurodegeneration

scientific article

Proteomics in animal models of Alzheimer's and Parkinson's diseases

scientific article published on 18 July 2008

Proteomics-determined differences in the concanavalin-A-fractionated proteome of hippocampus and inferior parietal lobule in subjects with Alzheimer's disease and mild cognitive impairment: implications for progression of AD.

scientific article published on February 2009

Proteomics: a new approach to investigate oxidative stress in Alzheimer's disease brain

scientific article published on March 2004

Quantitative phosphoproteomic analyses of the inferior parietal lobule from three different pathological stages of Alzheimer's disease

scientific article published on 22 September 2015

Quantitative proteomics analysis of differential protein expression and oxidative modification of specific proteins in the brains of old mice

scientific article published on 23 June 2005

Quantitative proteomics analysis of phosphorylated proteins in the hippocampus of Alzheimer's disease subjects ⬇️

scientific article published on April 13, 2011

Rat brain pro-oxidant effects of peripherally administered 5nm ceria 30 days after exposure ⬇️

scientific article published on June 28, 2012

Rat hippocampal responses up to 90 days after a single nanoceria dose extends a hierarchical oxidative stress model for nanoparticle toxicity

scientific article published on 18 December 2013

Reaching Out to Send a Message: Proteins Associated with Neurite Outgrowth and Neurotransmission are Altered with Age in the Long-Lived Naked Mole-Rat

scientific article

Redox Proteomics Analysis of Brains from Subjects with Amnestic Mild Cognitive Impairment Compared to Brains from Subjects with Preclinical Alzheimer's Disease: Insights into Memory Loss in MCI ⬇️

scientific article published on January 1, 2011

Redox Proteomics in Human Biofluids: Sample Preparation, Separation and Immunochemical Tagging for Analysis of Protein Oxidation

scientific article published on January 2016

Redox Proteomics: A Key Tool for New Insights into Protein Modification with Relevance to Disease

scientific article

Redox homeostasis and cellular stress response in aging and neurodegeneration

scientific article published on January 2010

Redox modulation of heat shock protein expression by acetylcarnitine in aging brain: relationship to antioxidant status and mitochondrial function

scientific article published in March 2006

Redox proteomic analysis of carbonylated brain proteins in mild cognitive impairment and early Alzheimer's disease

scientific article

Redox proteomic identification of 4-hydroxy-2-nonenal-modified brain proteins in amnestic mild cognitive impairment: insight into the role of lipid peroxidation in the progression and pathogenesis of Alzheimer's disease

scientific article

Redox proteomic identification of HNE-bound mitochondrial proteins in cardiac tissues reveals a systemic effect on energy metabolism after doxorubicin treatment

scientific article published on 12 March 2014

Redox proteomic identification of oxidized cardiac proteins in adriamycin-treated mice

scientific journal article

Redox proteomics

scientific article published on 9 July 2012

Redox proteomics analyses of the influence of co-expression of wild-type or mutated LRRK2 and Tau on C. elegans protein expression and oxidative modification: relevance to Parkinson disease

scientific article published on 20 March 2012

Redox proteomics analysis to decipher the neurobiology of Alzheimer-like neurodegeneration: overlaps in Down's syndrome and Alzheimer's disease brain.

scientific article

Redox proteomics and amyloid β-peptide: insights into Alzheimer disease

scientific article published on 27 November 2018

Redox proteomics and the dynamic molecular landscape of the aging brain

scientific article published on 25 December 2013

Redox proteomics identification of 4-hydroxynonenal-modified brain proteins in Alzheimer's disease: Role of lipid peroxidation in Alzheimer's disease pathogenesis

scientific article

Redox proteomics identification of oxidatively modified brain proteins in Alzheimer's disease and mild cognitive impairment: insights into the progression of this dementing disorder.

scientific article published on August 2007

Redox proteomics identification of oxidatively modified brain proteins in inherited Alzheimer's disease: an initial assessment

scientific article published in December 2006

Redox proteomics identification of oxidatively modified hippocampal proteins in mild cognitive impairment: insights into the development of Alzheimer's disease

scientific article published on 8 February 2006

Redox proteomics identification of oxidatively modified proteins in Alzheimer's disease brain and in vivo and in vitro models of AD centered around Abeta(1-42).

scientific article

Redox proteomics identification of oxidized proteins in Alzheimer's disease hippocampus and cerebellum: an approach to understand pathological and biochemical alterations in AD.

scientific article published on 4 November 2005

Redox proteomics in aging rat brain: involvement of mitochondrial reduced glutathione status and mitochondrial protein oxidation in the aging process

scientific article published on 8 October 2010

Redox proteomics in some age-related neurodegenerative disorders or models thereof

scientific article published on July 2006

Redox proteomics studies of in vivo amyloid beta‐peptide animal models of Alzheimer's disease: Insight into the role of oxidative stress ⬇️

scientific article published on 09 April 2008

Redox proteomics: from protein modifications to cellular dysfunction and disease

scientific article published in January 2014

Redox regulation in neurodegeneration and longevity: role of the heme oxygenase and HSP70 systems in brain stress tolerance

scientific article published in October 2004

Redox regulation of cellular stress response in neurodegenerative disorders

scientific article published on September 2006

Redox regulation of heat shock protein expression by signaling involving nitric oxide and carbon monoxide: relevance to brain aging, neurodegenerative disorders, and longevity

scientific article

Regional expression of key cell cycle proteins in brain from subjects with amnestic mild cognitive impairment

scientific article published on 28 September 2006

Rodent Abeta(1-42) exhibits oxidative stress properties similar to those of human Abeta(1-42): Implications for proposed mechanisms of toxicity.

scientific article published in October 2004

Role of 4-hydroxy-2-nonenal (HNE) in the pathogenesis of alzheimer disease and other selected age-related neurodegenerative disorders

scientific article

Role of glycine-33 and methionine-35 in Alzheimer's amyloid beta-peptide 1-42-associated oxidative stress and neurotoxicity

scientific article published in March 2002

Role of oxidative stress in the progression of Alzheimer's disease

scientific article published on January 2010

Role of phenylalanine 20 in Alzheimer's amyloid beta-peptide (1-42)-induced oxidative stress and neurotoxicity

scientific article published in December 2004

Role of the proteasome in protein oxidation and neural viability following low-level oxidative stress

scientific article published in July 2003

Roles of 3-nitrotyrosine- and 4-hydroxynonenal-modified brain proteins in the progression and pathogenesis of Alzheimer's disease ⬇️

scientific article published on October 13, 2010

Roles of amyloid beta-peptide-associated oxidative stress and brain protein modifications in the pathogenesis of Alzheimer's disease and mild cognitive impairment

scientific article

Specificity of biophysical and biochemical alterations in erythrocyte membranes in neurological diseases: Huntington's disease, Friedreich's ataxia, Alzheimer's disease, amyotrophic lateral sclerosis, and myotonic and Duchenne muscular dystrophy

scientific article published on January 1, 1979

Spin label and biochemical studies of erythrocyte membranes in Alzheimer's disease ⬇️

scientific article published on March 1, 1980

Striatal damage and oxidative stress induced by the mitochondrial toxin malonate are reduced in clorgyline-treated rats and MAO-A deficient mice

scientific article published in April 2004

Substitution of isoleucine-31 by helical-breaking proline abolishes oxidative stress and neurotoxic properties of Alzheimer's amyloid beta-peptide

scientific article published in June 2002

Superoxide induces protein oxidation in plasma and TNF-α elevation in macrophage culture: Insights into mechanisms of neurotoxicity following doxorubicin chemotherapy

scientific article published on 27 July 2015

Targeting Mitochondria in Alzheimer Disease: Rationale and Perspectives

scientific article published on 01 October 2019

The 2013 SFRBM discovery award: selected discoveries from the butterfield laboratory of oxidative stress and its sequela in brain in cognitive disorders exemplified by Alzheimer disease and chemotherapy induced cognitive impairment

scientific article

The G671V variant of MRP1/ABCC1 links doxorubicin-induced acute cardiac toxicity to disposition of the glutathione conjugate of 4-hydroxy-2-trans-nonenal ⬇️

scientific article published on April 1, 2012

The Lipid Peroxidation Product, 4‐Hydroxy‐2‐trans‐Nonenal, Alters the Conformation of Cortical Synaptosomal Membrane Proteins ⬇️

scientific article published on September 1, 1997

The Triangle of Death in Alzheimer's Disease Brain: The Aberrant Cross-Talk Among Energy Metabolism, Mammalian Target of Rapamycin Signaling, and Protein Homeostasis Revealed by Redox Proteomics

scientific article published on 14 September 2016

The antioxidant vitamin E modulates amyloid beta-peptide-induced creatine kinase activity inhibition and increased protein oxidation: implications for the free radical hypothesis of Alzheimer's disease

scientific article published in March 1999

The antioxidants alpha-lipoic acid and N-acetylcysteine reverse memory impairment and brain oxidative stress in aged SAMP8 mice

scientific article published in March 2003

The critical role of methionine 35 in Alzheimer's amyloid beta-peptide (1-42)-induced oxidative stress and neurotoxicity

scientific article

The expression of key oxidative stress-handling genes in different brain regions in Alzheimer's disease

scientific article published in October 1998

The expression of several mitochondrial and nuclear genes encoding the subunits of electron transport chain enzyme complexes, cytochrome c oxidase, and NADH dehydrogenase, in different brain regions in Alzheimer's disease

scientific article published in June 1999

The free radical antioxidant vitamin E protects cortical synaptosomal membranes from amyloid beta-peptide(25-35) toxicity but not from hydroxynonenal toxicity: relevance to the free radical hypothesis of Alzheimer's disease

scientific article published in November 1998

The glial glutamate transporter, GLT-1, is oxidatively modified by 4-hydroxy-2-nonenal in the Alzheimer's disease brain: the role of Abeta1-42.

scientific article published in July 2001

The glutamatergic system and Alzheimer's disease: therapeutic implications

scientific article

The hydrophobic environment of Met35 of Alzheimer's Abeta(1-42) is important for the neurotoxic and oxidative properties of the peptide

scientific article published in May 2002

The identification of protein biomarkers for oxidative stress in Down syndrome ⬇️

scientific article published on August 1, 2011

The role of charge in the toxicity of polymer-coated cerium oxide nanomaterials to Caenorhabditis elegans.

scientific article published on 6 September 2017

The senescence-accelerated prone mouse (SAMP8): a model of age-related cognitive decline with relevance to alterations of the gene expression and protein abnormalities in Alzheimer's disease

scientific article

The wheat germ agglutinin-fractionated proteome of subjects with Alzheimer's disease and mild cognitive impairment hippocampus and inferior parietal lobule: Implications for disease pathogenesis and progression

scientific article published on 8 October 2010

Tumor necrosis factor alpha-mediated nitric oxide production enhances manganese superoxide dismutase nitration and mitochondrial dysfunction in primary neurons: an insight into the role of glial cells

scientific article published on 13 November 2007

Vitamin D deficiency and Alzheimer disease: Common links

scientific article published on 06 July 2015

Vitamin E Prevents Alzheimer's Amyloid beta-Peptide (1-42)-Induced Neuronal Protein Oxidation and Reactive Oxygen Species Production

scientific article published in June 2000

Vitamin E and neurodegenerative disorders associated with oxidative stress

scientific article

Vitamin E is essential for Purkinje neuron integrity

scientific article published on 14 December 2013

mTOR signaling in aging and neurodegeneration: At the crossroad between metabolism dysfunction and impairment of autophagy

scientific article published on 19 March 2015

mTOR: Alzheimer's disease prevention for APOE4 carriers

scientific article published on 30 June 2016

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