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List of works by J A García-Sáinz

"Pertussis toxin induces tachycardia and impairs the increase in blood pressure produced by alpha 2-adrenergic agonists"

scientific article published on 01 December 1983

Activation of endothelin ETA receptors induces phosphorylation of alpha1b-adrenoreceptors in Rat-1 fibroblasts.

scientific article published on October 1997

Activation of lipolysis and cyclic AMP accumulation in rabbit adipocytes by isoproterenol in the presence of forskolin or pertussis toxin

scientific article published on 01 April 1984

Adrenergic regulation of ureogenesis in hepatocytes from adrenalectomized rats. Possible involvement of two pathways of signal transduction in alpha 1-adrenergic action

scientific article published on 01 January 1984

Agonist-induced interactions between angiotensin AT1 and epidermal growth factor receptors.

scientific article

Alpha 1-adrenoceptor activation stimulates ureogenesis in rat hepatocytes

scientific article published on 01 July 1981

Alpha 1-adrenoceptor subtype selectivity of tamsulosin: studies using livers from different species

scientific article published on 01 March 1995

Alpha 1-adrenoceptor subtypes in aorta (alpha 1A) and liver (alpha 1B)

scientific article published on 01 March 1991

Alpha 1-adrenoceptors: subtypes, signaling, and roles in health and disease.

scientific article

Alpha 2 adrenergic amines, adenosine and prostaglandins inhibit lipolysis and cyclic AMP accumulation in hamster adipocytes in the absence of extracellular sodium

scientific article published on 01 January 1981

Alpha1-adrenergic activation of phosphatidylinositol labeling in isolated brown fat cells

scientific article published on 01 December 1980

Alpha1-adrenoceptor subtype activation increases proto-oncogene mRNA levels. Role of protein kinase C

scientific article published on 01 January 1998

Angiotensin AT1 receptors in Clone 9 rat liver cells: Ca2+ signaling and c-fos expression.

scientific article published on December 1998

Angiotensin II and active phorbol esters induce proto-oncogene expression in isolated rat hepatocytes

scientific article published on September 9, 1992

Angiotensin II inhibits the accumulation of cyclic AMP produced by glucagon but not its metabolic effects

scientific article published on 01 June 1982

Angiotensin II stimulates phosphoinositide turnover and phosphorylase through AII-1 receptors in isolated rat hepatocytes

scientific article published on 01 October 1990

Atypical angiotensin II receptors coupled to phosphoinositide turnover/calcium signalling in catfish hepatocytes

scientific article published on 01 June 1997

Beta 1-adrenoceptors in rat hepatoma. Desensitization by isoproterenol and phorbol-myristate-acetate

scientific article published on 01 January 1989

Characterization and detoxification of an easily prepared acellular pertussis vaccine. Antigenic role of the A protomer of pertussis toxin

scientific article published on 01 January 1992

Characterization of the alpha 1-adrenoceptors of cat liver. Predominance of the alpha 1A-adrenergic subtype

scientific article published on 01 January 1996

Characterization of the alpha 1-adrenoceptors of dog liver: predominance of the alpha 1A-subtype

scientific article published on 01 January 1995

Characterization of the alpha 1B-adrenergic receptors of chicken hepatocytes. Signal transduction and actions

scientific article published on 01 November 1993

Characterization of the alpha 1B-adrenoceptors of catfish hepatocytes: functional and binding studies

scientific article published on 01 January 1995

Characterization of the hepatic alpha 1B-adrenoceptors of rats, mice and hamsters

scientific journal article

Characterization of the human liver alpha 1-adrenoceptors: predominance of the alpha 1A subtype

scientific article published on 01 March 1995

Chloroquine inhibits α1B-adrenergic action in hepatocytes ⬇️

scientific article published on January 26, 1998

Coexpression of alpha 1A- and alpha 1B-adrenoceptors in the liver of the rhesus monkey (Macaca mulatta)

scientific article published on 01 September 1996

Conventional protein kinase C isoforms mediate phorbol ester-induced lysophosphatidic acid LPA1 receptor phosphorylation.

scientific article published on 16 December 2013

Cross-talk between receptors with intrinsic tyrosine kinase activity and alpha1b-adrenoceptors.

scientific article published on September 2000

Crosstalk: phosphorylation of alpha1b-adrenoceptors induced through activation of bradykinin B2 receptors.

scientific article

Cycloheximide: an adrenergic agent

scientific article published on 01 May 1982

Decreased sensitivity to α2 adrenergic amines, adenosine and prostaglandins in white fat cells from hamsters treated with pertussis vaccine ⬇️

scientific article published on April 20, 1981

Differences in phorbol ester-induced decrease of the activity of protein kinase C isozymes in rat hepatocytes

scientific article published on 01 August 1991

Differential effects of adrenergic agonists and phorbol esters on the alpha 1-adrenoceptors of hepatocytes and aorta

scientific article published on 01 June 1985

Differential phosphorylation, desensitization, and internalization of α1A-adrenoceptors activated by norepinephrine and oxymetazoline.

scientific article published on 30 January 2013

Direct action of pertussis toxin in isolated hamster fat cells

scientific article published on 01 March 1984

Dissecting how receptor tyrosine kinases modulate G protein-coupled receptor function.

scientific article published on 07 September 2010

Distinct phosphorylation sites/clusters in the carboxyl terminus regulate α1D-adrenergic receptor subcellular localization and signaling

scientific article published on 09 November 2018

Effect of insulin on alpha1-adrenergic actions in hepatocytes from euthyroid and hypothyroid rats. Possible involvement of two pathways in alpha1-adrenergic actions

scientific article published on 01 January 1984

Effect of okadaic acid on hormone- and mastoparan-stimulated phosphoinositide turnover in isolated rat hepatocytes

scientific article published on 01 September 1991

Effect of pertussis toxin on alpha 2-adrenoceptors: decreased formation of the high-affinity state for agonists

scientific article published on 01 June 1984

Effect of pertussis toxin on hormonal responsiveness of rat hepatocytes

scientific article published on 01 August 1983

Effect of pertussis toxin on the adrenergic regulation of plasma renin activity

scientific article published on 01 October 1984

Effect of pertussis toxin on the heart acetylcholine muscarinic receptor affinity

scientific article published on 01 August 1986

Effect of pertussis toxin on the heart muscarinic-cholinergic receptors and their function

scientific article published on 01 August 1986

Effect of pertussis toxin on the hormonal regulation of cyclic AMP levels in hamster fat cells

scientific article published on 01 October 1983

Effect of pertussis toxin on water metabolism in the rat

scientific article published on 01 January 1986

Effect of pertussis vaccine on alpha-adrenoceptors of the circulatory system of the rat

scientific article published on 01 September 1982

Effect of phorbol esters on the hormonal responsiveness of isolated white fat cells.

scientific article

Effects of [1-N alpha-trinitrophenylhistidine, 12-homoarginine]glucagon on cyclic AMP levels and free fatty acid release in isolated rat adipocytes.

scientific article

Effects of adenosine on ethanol-induced modifications of liver metabolism. Role of hepatic redox state, purine and fatty acid metabolism

scientific article published on 01 June 1980

Effects of adenosine on liver cell damage induced by carbon tetrachloride

scientific article published on 01 August 1984

Effects of pertussis vaccine on the lipid metabolism of hamsters

scientific article published on 01 September 1981

Estrogens cross-talk to alpha1b-adrenergic receptors.

scientific article published on 25 April 2006

Forskolin effects on the beta-adrenergic responsiveness of rat hepatocytes

scientific article published on 01 October 1984

Free fatty acids and protein kinase C activation induce GPR120 (free fatty acid receptor 4) phosphorylation.

scientific article

G protein-coupled receptor cross-talk: pivotal roles of protein phosphorylation and protein-protein interactions.

scientific article

Glycyl-histidyl-lysine interacts with the angiotensin II AT1 receptor

scientific article published on 01 January 1995

Guanine nucleotide-induced positive cooperativity in muscarinic-cholinergic antagonist binding

scientific article published on 01 January 1986

Guinea pig hepatocyte alpha 1A-adrenoceptors: characterization, signal transduction and regulation

scientific article published on 01 November 1992

H1-histaminergic activation stimulates phosphatidylinositol labeling in rabbit aorta

scientific article published on 01 June 1983

Hepatocyte homologous beta 2-adrenergic desensitization is associated with a decrease in number of plasma membrane beta 2-adrenoceptors

scientific article published on 01 January 1993

Histamine activates phosphorylase and inositol phosphate production in guinea pig hepatocytes.

scientific article

Homologous and heterologous beta-adrenergic desensitization in hepatocytes. Additivity and effect of pertussis toxin

scientific article published on 01 December 1988

Homologous and heterologous desensitization of one of the pathways of the alpha 1-adrenergic action. Effects of epinephrine, vasopressin, angiotensin II and phorbol 12-myristate 13-acetate

scientific article published on 01 June 1986

Hormonal Responsiveness of Hepatocytes After Hypothermic Preservation in University of Wisconsin Solution ⬇️

scientific article published on May 1, 1997

Hormonal modulation of c-fos expression in isolated hepatocytes. Effects of angiotensin II and phorbol myristate acetate on transcription and mRNA degradation

scientific article published on 01 February 1996

Human alpha1D-adrenoceptor phosphorylation and desensitization.

scientific article published on May 2004

Importance of the esterification process in adipose tissue metabolism as evidenced by cycloheximide

scientific article published on 01 January 1978

Inhibition of hormone-stimulated inositol phosphate production and disruption of cytoskeletal structure. Effects of okadaic acid, microcystin, chlorpromazine, W7 and nystatin.

scientific article published in January 1994

Inositol administration restores the sensitivity of liver cells formed during liver regeneration to alpha 1-adrenergic amines, vasopressin and angiotensin II

scientific article published on 01 September 1983

Insulin induces alpha1B-adrenergic receptor phosphorylation and desensitization.

scientific article

Insulin-like effect of epidermal growth factor in isolated rat hepatocytes. Modulation of the alpha-1-adrenergic stimulation of ureagenesis

scientific article published on 01 November 1986

Insulin-like growth factor-I induces alpha(1B)-adrenergic receptor phosphorylation through G beta gamma and epidermal growth factor receptor transactivation.

scientific article published on 27 June 2006

Intracellular calcium and alpha 1b-adrenoceptor phosphorylation

scientific article published on 01 September 1999

Inverse alpha(1A) and alpha(1D) adrenoceptor mRNA expression during isolation of hepatocytes

scientific article published on 01 November 1999

Isoforms of protein kinase C involved in phorbol ester-induced sphingosine 1-phosphate receptor 1 phosphorylation and desensitization

scientific article published on 13 November 2013

Lipogenic action of cycloheximide on the rat epididymal fat pad

scientific article published on April 15, 1975

Mechanism of the fatty liver induced by cycloheximide and its reversibility by adenosine.

scientific article published on April 1979

Mechanisms involved in α1B-adrenoceptor desensitization.

scientific article published on 03 August 2011

Metabolic effects and cyclic AMP levels produced by glucagon, (1-N alpha-Trinitrophenylhistidine,12-homoarginine)glucagon and forskolin in isolated rat hepatocytes

scientific article published on 01 August 1984

Modulation by thyroid status of cyclic AMP-dependent and Ca2+-dependent mechanisms of hormone action in rat liver cells. Possible involvement of two different transduction mechanisms in alpha 1-adrenergic action

scientific article published on 01 February 1984

Modulation of basal intracellular calcium by inverse agonists and phorbol myristate acetate in rat-1 fibroblasts stably expressing alpha1d-adrenoceptors.

scientific article published on January 1999

Modulation of glucagon actions by phorbol myristate acetate in isolated hepatocytes. Effect of hypothyroidism

scientific article published on 01 January 1990

Okadaic acid increases the phosphorylation state of alpha1A-adrenoceptors and induces receptor desensitization.

scientific article published on 17 November 2005

On the mechanism of ethanol-induced fatty liver and its reversibility by adenosine ⬇️

scientific article published on September 1, 1978

Peroxovanadate induces alpha 1B-adrenoceptor phosphorylation and association with protein kinase C.

scientific article published on February 2004

Pertussis toxin catalyzes the ADP-ribosylation of two distinct peptides, 40 and 41 kDa, in rat fat cell membranes

scientific article published on 01 October 1984

Pertussis toxin enhances the beta-adrenergic and blocks the alpha 2-adrenergic regulation of renin secretion in renal cortical slices.

scientific article

Pertussis toxin reverses Gpp(NH)p inhibition of basal and forskolin activated adipocyte adenylate cyclase

scientific article published on 01 October 1983

Phorbol esters and calcium-mobilizing hormones increase membrane-associated protein kinase C activity in rat hepatocytes ⬇️

scientific article published on January 18, 1988

Phorbol esters inhibit alpha 1 adrenergic stimulation of glycogenolysis in isolated rat hepatocytes

scientific article published on 01 March 1984

Phorbol esters, vasopressin and angiotensin II block alpha 1-adrenergic action in rat hepatocytes. Possible role of protein kinase C

scientific article published on 01 June 1986

Phosphorylation and desensitization of the lysophosphatidic acid receptor LPA1.

scientific article published on February 2005

Possible existence of two mechanisms involved in alpha 1-adrenergic action: effect of Sgd 101/75.

scientific article published on June 1986

Possible involvement of cyclooxygenase products in the actions of platelet-activating factor and of lipoxygenase products in the vascular effects of epinephrine in perfused rat liver

scientific article published on 01 September 1984

Protein kinase C-alpha(1b)-adrenoceptor coimmunoprecipitation: effect of hormones and phorbol myristate acetate.

scientific article published on May 2001

Protein kinases and phosphatases modulate c-fos expression in rat hepatocytes. Effects of angiotensin II and phorbol myristate acetate

scientific article published on 01 January 1995

Purification and characterization of receptors for activated protein kinase C from rat hepatocytes

scientific article published on 01 June 1997

RX781094 a potent and selective alpha 2-adrenergic antagonist. Effects in adipocytes and hepatocytes

scientific article published on 01 April 1984

Receptor tyrosine kinases regulate alpha1D-adrenoceptor signaling properties: phosphorylation and desensitization.

scientific article

Regulation of LPA receptor function by estrogens

scientific journal article

Role of alpha 1 adrenoceptors in the turnover of phosphatidylinositol and of alpha 2 adrenoceptors in the regulation of cyclic AMP accumulation in hamster adipocytes

scientific article published on 01 September 1980

Role of epidermal growth factor receptor transactivation in alpha1B-adrenoceptor phosphorylation.

scientific article published on 27 May 2006

Role of phosphatidylinositol turnover in alpha 1 and of adenylate cyclase inhibition in alpha 2 effects of catecholamines.

scientific article

Roles of alpha 1- and beta-adrenergic receptors in adrenergic responsiveness of liver cells formed after partial hepatectomy

scientific article published on 01 September 1983

Roles of c-Src in alpha1B-adrenoceptor phosphorylation and desensitization.

scientific article

Roles of phosphoinositide-dependent kinase-1 in α1B-adrenoceptor phosphorylation and desensitization ⬇️

scientific article published on November 21, 2011

Roles of the α1A-adrenergic receptor carboxyl tail in protein kinase C-induced phosphorylation and desensitization.

scientific article published on 5 October 2010

S1P receptor phosphorylation, internalization and interaction with Rab proteins: effects of sphingosine 1-phosphate, FTY720-P, phorbol esters and paroxetine

scientific article published on 11 December 2018

Sensitivity of liver cells formed after partial hepatectomy to glucagon, vasopressin and angiotensin II

scientific article published on 01 September 1983

Species heterogeneity of hepatic alpha 1-adrenoceptors: alpha 1A-, alpha 1B- and alpha 1C-subtypes

scientific article published on 01 July 1992

Sphingosine 1-phosphate-mediated α1B-adrenoceptor desensitization and phosphorylation. Direct and paracrine/autocrine actions.

scientific article

Stimulation of ureogenesis through alpha 1- and beta-adrenoceptors in juvenile rat hepatocytes

scientific article published on 01 August 1982

The elusive alpha(1D)-adrenoceptor: molecular and cellular characteristics and integrative roles.

scientific article published in October 2004

Updates in the function and regulation of α1 -adrenoceptors

scientific article published on 01 April 2019

Vasopressin and angiotensin II stimulate ureogenesis through increased mitochondrial citrulline production

scientific article published on 01 November 1982

Visualizing G protein-coupled receptors in action through confocal microscopy techniques.

scientific article published on 18 April 2014

alpha1B-Adrenergic receptor phosphorylation and desensitization induced by transforming growth factor-beta.

scientific article published in December 2002

α(1D)-Adrenergic receptors constitutive activity and reduced expression at the plasma membrane

scientific article published on January 1, 2010

α1B-adrenergic receptors differentially associate with Rab proteins during homologous and heterologous desensitization

scientific article

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