List of works by Xiongwei Zhu

A conserved retromer sorting motif is essential for mitochondrial DLP1 recycling by VPS35 in Parkinson's disease model

scientific article published on 30 December 2016

A low-molecular-weight ferroxidase is increased in the CSF of sCJD cases: CSF ferroxidase and transferrin as diagnostic biomarkers for sCJD.

scientific article published on 16 April 2013

A novel origin for granulovacuolar degeneration in aging and Alzheimer's disease: parallels to stress granules

scientific article

A second look into the oxidant mechanisms in Alzheimer's disease

scientific article

A synergistic dysfunction of mitochondrial fission/fusion dynamics and mitophagy in Alzheimer's disease

scientific article

Aberrant expression of metabotropic glutamate receptor 2 in the vulnerable neurons of Alzheimer's disease

scientific article published on 11 February 2004

Aberrant localization of importin alpha1 in hippocampal neurons in Alzheimer disease

scientific article published on 27 October 2006

Abnormal mitochondrial dynamics and neurodegenerative diseases

scientific article published on 30 September 2009

Abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease

scientific article

Abnormal mitochondrial dynamics--a novel therapeutic target for Alzheimer's disease?

scientific article published on 27 January 2010

Absence of cellular stress in brain after hypoxia induced by arousal from hibernation in Arctic ground squirrels

scientific article published on 23 June 2005

Accumulation of intraneuronal amyloid-β is common in normal brain.

scientific article

Activation of Akt by lithium: pro-survival pathways in aging

scientific article published on 3 January 2009

Activation of P38 kinase links π phosphorylation, oxidative stress and cell cycle-related events in Alzheimer disease

Activation of the extracellular signal-regulated kinase pathway contributes to the behavioral deficit of fragile x-syndrome

scientific article published on 27 March 2012

All-trans retinoic acid as a novel therapeutic strategy for Alzheimer's disease

scientific article

Altered redox balance in disease: Can we change the new equilibria?

Alzheimer Disease: Oxidative Stress and Compensatory Responses

article

Alzheimer disease and the role of free radicals in the pathogenesis of the disease

scientific article published on February 2008

Alzheimer disease pathology as a host response

scientific article published on June 2008

Alzheimer disease, the two-hit hypothesis: an update

scientific article published on 27 October 2006

Alzheimer disease: evidence for a central pathogenic role of iron-mediated reactive oxygen species

scientific article published on April 2004

Alzheimer's Disease: Advances for a New Century

scholarly article by George Perry et al published 27 December 2012 in Journal of Alzheimer's Disease

Alzheimer's disease and the cell cycle

scientific article published on January 2004

Alzheimer's disease and vascular deficiency: lessons from imaging studies and down syndrome

scientific article published on 15 February 2012

Alzheimer's disease: an intracellular movement disorder?

scientific article published in September 2005

Alzheimer's disease: cerebrovascular dysfunction, oxidative stress, and advanced clinical therapies

scientific article published on October 2008

Alzheimer's disease: diverse aspects of mitochondrial malfunctioning

scientific article

Alzheimer's disease: the two-hit hypothesis

scientific article published on April 2004

Alzheimer-specific epitopes of tau represent lipid peroxidation-induced conformations

scientific article

Alzheimers Disease and Oxidative Stress: The Old Problem Remains Unsolved

scholarly article published 1 March 2005

Alzheimer’s disease therapy: a moving target

Amyloid Beta and tau proteins as therapeutic targets for Alzheimer's disease treatment: rethinking the current strategy

scientific article published on 8 March 2012

Amyloid beta: the alternate hypothesis

scientific article

Amyloid-beta in Alzheimer's disease: the horse or the cart? Pathogenic or protective?

scientific article

Amyloid-beta overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins

scholarly article

Amyloid-beta vaccination: testing the amyloid hypothesis?: heads we win, tails you lose!

scientific article published on September 2006

Amyloid-beta, tau alterations and mitochondrial dysfunction in Alzheimer disease: the chickens or the eggs?

scientific article

Amyloid-beta-derived diffusible ligands cause impaired axonal transport of mitochondria in neurons

scientific article published on 13 February 2010

Amyloid-beta42 interacts mainly with insoluble prion protein in the Alzheimer brain

scientific article

Amyloid-β metabolite sensing: biochemical linking of glycation modification and misfolding

scientific article published in January 2012

Amyloids, Aggregates and Neuronal Inclusions: Good or Bad News for Neurons?

article

Amyotrophic lateral sclerosis: a novel hypothesis involving a gained 'loss of function' in the JNK/SAPK pathway

scientific article

Antigen-antibody dissociation in Alzheimer disease: a novel approach to diagnosis

scientific article

Antimicrobial peptide β-defensin-1 expression is upregulated in Alzheimer's brain

scientific article published on 18 October 2013

Antioxidant approaches for the treatment of Alzheimer's disease

scientific article published on July 2010

Antioxidant therapy in Alzheimer's disease: theory and practice

scientific article

Apolipoprotein E4 prevents growth of malaria at the intraerythrocyte stage: implications for differences in racial susceptibility to Alzheimer's disease

scientific article

Apoptosis in Alzheimer disease: a mathematical improbability

scientific article published on September 2006

Apoptotic and Oxidative Indicators in Alzheimer's Disease

scholarly article

Apoptotic promoters and inhibitors in Alzheimer's disease: Who wins out?

scientific article

Ascorbate distribution during hibernation is independent of ascorbate redox state

scientific article published in August 2004

Autophagocytosis of mitochondria is prominent in Alzheimer disease

scientific article

Autophagy in Alzheimer's disease

scientific article published on July 2010

BRCA1 may modulate neuronal cell cycle re-entry in Alzheimer disease

scientific article published on 12 May 2007

Beyond estrogen: targeting gonadotropin hormones in the treatment of Alzheimer's disease

scientific article published in August 2004

Biomarkers in Alzheimer's disease: past, present and future

scientific article

Birth of JAD: 20 Years Later.

scientific article published in January 2018

CD3 in Lewy pathology: does the abnormal recall of neurodevelopmental processes underlie Parkinson's disease

scientific article

Causes versus effects: the increasing complexities of Alzheimer's disease pathogenesis

scientific article

Cell cycle deregulation in the neurons of Alzheimer's disease

scientific article published on January 2011

Cell cycle re-entry and mitochondrial defects in myc-mediated hypertrophic cardiomyopathy and heart failure

scientific article

Cell cycle re-entry mediated neurodegeneration and its treatment role in the pathogenesis of Alzheimer's disease

scientific article published on 09 December 2008

Cellular prion protein is essential for oligomeric amyloid-β-induced neuronal cell death

scientific article published on 18 November 2011

Challenging the amyloid cascade hypothesis: senile plaques and amyloid-beta as protective adaptations to Alzheimer disease

scientific article published in June 2004

Chapter 19. Targeting Oxidative Mechanisms in Alzheimer Disease

Chronic Leptin Supplementation Ameliorates Pathology and Improves Cognitive Performance in a Transgenic Mouse Model of Alzheimer's Disease

scientific article published in December 2009

Chronic oxidative stress causes increased tau phosphorylation in M17 neuroblastoma cells

scientific article

Chronological primacy of oxidative stress in Alzheimer disease.

scientific article published in May 2005

Clinical and imaging characteristics of late onset mitochondrial membrane protein-associated neurodegeneration (MPAN)

scientific article published on November 2016

Comparative biology and pathology of oxidative stress in Alzheimer and other neurodegenerative diseases: beyond damage and response

scientific article

Compensatory responses induced by oxidative stress in Alzheimer disease

scientific article

Consequences of RNA oxidation on protein synthesis rate and fidelity: implications for the pathophysiology of neuropsychiatric disorders

scientific article

Contribution of redox-active iron and copper to oxidative damage in Alzheimer disease

scientific article published in July 2004

Correction: Individual Case Analysis of Postmortem Interval Time on Brain Tissue Preservation

scientific article published on 3 June 2016

Correction: Prion Protein Protects against Renal Ischemia/Reperfusion Injury

scientific article published on 15 October 2015

Curcumin/melatonin hybrid 5-(4-hydroxy-phenyl)-3-oxo-pentanoic acid [2-(5-methoxy-1H-indol-3-yl)-ethyl]-amide ameliorates AD-like pathology in the APP/PS1 mouse model

scientific article published on 20 April 2015

DLP1-dependent mitochondrial fragmentation mediates 1-methyl-4-phenylpyridinium toxicity in neurons: implications for Parkinson's disease

scientific article published on 14 June 2011

Decline in mitochondrial bioenergetics underlies central insulin resistance in streptozocin-induced model of sporadic Alzheimer's disease

scholarly article by Sónia Correia et al published July 2011 in Alzheimer's and Dementia

Detection and localization of markers of oxidative stress by in situ methods: application in the study of Alzheimer disease

scientific article published in January 2010

Differential regulation of glutamate receptors in Alzheimer's disease

scientific article

Dissociated Aβ antibody level in newly diagnosed Alzheimer's disease: A population-based study

article

Distribution, levels and phosphorylation of Raf-1 in Alzheimer's disease

scientific article

Disturbance in AMP-activated protein kinase (AMPK) signaling pathway in Alzheimer's disease

Divalent metal transporter, iron, and Parkinson's disease: a pathological relationship.

scientific article

Down-regulation of aminolevulinate synthase, the rate-limiting enzyme for heme biosynthesis in Alzheimer's disease

scientific article

Down-regulation of serum gonadotropins but not estrogen replacement improves cognition in aged-ovariectomized 3xTg AD female mice

scientific article

Down-regulation of serum gonadotropins is as effective as estrogen replacement at improving menopause-associated cognitive deficits

scientific article

Dynamin-like protein 1 cleavage by calpain in Alzheimer's disease.

scientific article published on 14 February 2019

Dynamin-like protein 1 reduction underlies mitochondrial morphology and distribution abnormalities in fibroblasts from sporadic Alzheimer's disease patients

scientific article published on 3 July 2008

Dysregulation of leptin signaling in Alzheimer disease: evidence for neuronal leptin resistance

scientific article published on 21 August 2013

Early induction of c-Myc is associated with neuronal cell death

scientific article published on 8 October 2011

Early induction of oxidative stress in mouse model of Alzheimer disease with reduced mitochondrial superoxide dismutase activity

scientific article

Ectopic expression of phospho-Smad2 in Alzheimer's disease: uncoupling of the transforming growth factor-beta pathway?

scientific article published in December 2006

Ectopic localization of FOXO3a protein in Lewy bodies in Lewy body dementia and Parkinson's disease

scientific article published on 23 July 2009

Ectopic localization of phosphorylated histone H3 in Alzheimer's disease: a mitotic catastrophe?

scientific article published on 26 February 2003

Elevated expression of a regulator of the G2/M phase of the cell cycle, neuronal CIP-1-associated regulator of cyclin B, in Alzheimer's disease

scientific article

Emerging evidence for the neuroprotective role of alpha-synuclein

scientific article

Estrogen receptor-α is localized to neurofibrillary tangles in Alzheimer's disease

scientific article published on 3 February 2016

Evidence for Oxidative Damage in the Autistic Brain

article

Evidence of DNA damage in Alzheimer disease: phosphorylation of histone H2AX in astrocytes

scientific article published on 23 April 2008

Expression of CD74 is increased in neurofibrillary tangles in Alzheimer's disease

scientific article published on 11 September 2008

Ferric cycle activity and Alzheimer disease

scientific article

Frontiers in Alzheimer's disease therapeutics

scientific article

Genome-wide analysis of DNA methylation during antagonism of DMOG to MnCl2-induced cytotoxicity in the mouse substantia nigra

scientific article

Getting the iron out: phlebotomy for Alzheimer's disease?

scientific article published on 04 February 2009

Glutaredoxin deficiency exacerbates neurodegeneration in C. elegans models of Parkinson's disease

scientific article

Glycogen synthase kinase 3: a point of integration in Alzheimer's disease and a therapeutic target?

scientific article

Heme catabolism and heme oxygenase in neurodegenerative disease

scientific article published in October 2004

Heme deficiency in Alzheimer's disease: a possible connection to porphyria

scientific article (publication date: 2006)

Heme-a, the heme prosthetic group of cytochrome c oxidase, is increased in Alzheimer's disease

scientific article published on 17 June 2009

Hibernation, a Model of Neuroprotection

High-resolution analytical imaging and electron holography of magnetite particles in amyloid cores of Alzheimer's disease

scientific article published on 28 April 2016

Hydroxynonenal-generated crosslinking fluorophore accumulation in Alzheimer disease reveals a dichotomy of protein turnover

scientific article published on 12 November 2011

Impaired balance of mitochondrial fission and fusion in Alzheimer's disease

scientific journal article

Impaired mitochondrial biogenesis contributes to mitochondrial dysfunction in Alzheimer's disease

scientific article published on 8 December 2011

In Memoriam: Mark A. Smith, PhD

In Memoriam: Mark A. Smith, PhD: Neuroscientist and Visionary

In Vivo and In Silico Evidence: Hippocampal Cholesterol Metabolism Decreases with Aging and Increases with Alzheimers Disease -- Modeling Brain Aging and Disease

Increased expression of p130 in Alzheimer disease

scientific article published on 28 September 2006

Increased iron and free radical generation in preclinical Alzheimer disease and mild cognitive impairment

scientific article

Increased isoprostane and prostaglandin are prominent in neurons in Alzheimer disease

scientific article published on 22 January 2007

Increased p27, an essential component of cell cycle control, in Alzheimer's disease

scientific article published in April 2003

Individual Case Analysis of Postmortem Interval Time on Brain Tissue Preservation

scientific article

Indoleamine 2,3-dioxygenase and 3-hydroxykynurenine modifications are found in the neuropathology of Alzheimer's disease

scientific article

Inhibition of mitochondrial fragmentation protects against Alzheimer's disease in rodent model

scientific article

Insights into amyloid-beta-induced mitochondrial dysfunction in Alzheimer disease

scientific article published on 21 September 2007

Insights into the Impact of a Membrane-Anchoring Moiety on the Biological Activities of Bivalent Compounds As Potential Neuroprotectants for Alzheimer's Disease

scientific article published on 22 December 2017

Insulin and Insulin-Sensitizing Drugs in Neurodegeneration: Mitochondria as Therapeutic Targets

scientific article published on 23 December 2009

Insulin is a two-edged knife on the brain

scientific article published on January 2009

Insulin signaling, diabetes mellitus and risk of Alzheimer disease.

scientific article

Insulin-resistant brain state: the culprit in sporadic Alzheimer's disease?

scientific article

Intraneuronal amyloid beta accumulation and oxidative damage to nucleic acids in Alzheimer disease

scientific article

Involvement of oxidative stress in Alzheimer disease

scientific article

Ionizing radiation causes increased tau phosphorylation in primary neurons

scientific article

Iron: A Pathological Mediator of Alzheimer Disease?

scientific article

Iron: the Redox-active center of oxidative stress in Alzheimer disease

scientific article published on 17 May 2007

Is Alzheimer's disease a mitochondrial disorder?

scientific article

Is oxidative damage the fundamental pathogenic mechanism of Alzheimer's and other neurodegenerative diseases?

scientific article

JKK1, an upstream activator of JNK/SAPK, is activated in Alzheimer's disease

scientific article published in April 2003

Kinase inhibitors arrest neurodegeneration in cell and C. elegans models of LRRK2 toxicity

scientific article

LRRK2 in Parkinson's disease and dementia with Lewy bodies

scientific article

LRRK2 protein is a component of lewy bodies

LRRK2 regulates mitochondrial dynamics and function through direct interaction with DLP1

scientific article

LRRK2-mediated neurodegeneration and dysfunction of dopaminergic neurons in a Caenorhabditis elegans model of Parkinson's disease

scientific article

Leptin inhibits glycogen synthase kinase-3beta to prevent tau phosphorylation in neuronal cells

scientific article published on 25 March 2009

Leptin reduces Alzheimer's disease-related tau phosphorylation in neuronal cells

scientific article published on 16 September 2008

Leptin reduces pathology and improves memory in a transgenic mouse model of Alzheimer's disease

scientific article

Leptin: a novel therapeutic strategy for Alzheimer's disease

scientific article

Leucine-rich repeat kinase 2 colocalizes with alpha-synuclein in Parkinson's disease, but not tau-containing deposits in tauopathies

scientific article published on 06 March 2008

Lipoic acid and N-acetyl cysteine decrease mitochondrial-related oxidative stress in Alzheimer disease patient fibroblasts.

scientific article published on September 2007

Lipoic acid and N-acetyl cysteine protect against mitochondrial-related oxidative stress in fibroblasts from Alzheimer disease patients

Luteinizing hormone downregulation but not estrogen replacement improves ovariectomy-associated cognition and spine density loss independently of treatment onset timing.

scientific article

MAPKs are differentially modulated in arctic ground squirrels during hibernation

scientific article published in June 2005

Mark A. Smith

Mark A. Smith, 1965-2010: consummate student of pathogenesis

scientific article published on 10 October 2011

Mark A. Smith, PhD: Renegade Scientist and Visionary

Mark A. Smith: neurocytochemistry innovator

scientific article published on 23 January 2012

Mark A. Smith: the scientist, the man.

scientific article published in October 2011

Mark Anthony Smith (1965-2010): Visionary, Alzheimer researcher, and editor-in-chief of the Journal of Alzheimer's Disease

scientific article published in January 2011

Mark Smith: Pioneer of Alzheimer Disease Research

Melatonin exhibits antioxidant properties in a mouse brain slice model of excitotoxicity

scientific article

Memantine: "hypothesis testing" not "disease modifying" in Alzheimer's disease

scientific article

Metal Homeostasis and Its Relation to Oxidative Stress in Alzheimer’s Disease

Mfn2 protects dopaminergic neurons exposed to paraquat both in vitro and in vivo: Implications for idiopathic Parkinson's disease

scientific article published on 16 February 2017

Microbial origin of glutamate, hibernation and tissue trauma: an in vivo microdialysis study

scientific article published in September 2002

Microtubule Reduction in Alzheimer's Disease and Aging Is Independent of τ Filament Formation ⬇️

scientific article published on May 1, 2003

Miro1 deficiency in amyotrophic lateral sclerosis

scientific article published on 26 May 2015

Mislocalization of CDK11/PITSLRE, a regulator of the G2/M phase of the cell cycle, in Alzheimer disease

scientific article

Mitochondria and Neurodegenerative Diseases

Mitochondria: a therapeutic target in neurodegeneration

scientific article published on 21 October 2009

Mitochondria: the missing link between preconditioning and neuroprotection

scientific article

Mitochondrial DNA oxidative damage and repair in aging and Alzheimer's disease

scientific article published on 7 December 2012

Mitochondrial Drugs for Alzheimer Disease

scientific article

Mitochondrial abnormalities and oxidative imbalance in Alzheimer disease.

scientific article published on July 2006

Mitochondrial abnormalities and oxidative imbalance in neurodegenerative disease.

scientific article published on 16 October 2002

Mitochondrial defects and oxidative stress in Alzheimer disease and Parkinson disease

scientific article

Mitochondrial dynamic abnormalities in amyotrophic lateral sclerosis

scientific article published on 29 July 2015

Mitochondrial dynamics in Alzheimer's disease: opportunities for future treatment strategies

scientific article

Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology

scientific article published on 21 October 2009

Mitochondrial failures in Alzheimer's disease

scientific article

Mitochondrial importance in Alzheimer's, Huntington's and Parkinson's diseases

scientific article published on January 2012

Mitochondrial preconditioning: a potential neuroprotective strategy

scientific article published on 26 August 2010

Mitogen- and stress-activated protein kinase 1: convergence of the ERK and p38 pathways in Alzheimer's disease

scientific article published in February 2005

Modulation of Parkinson's Disease Associated Protein Rescues Alzheimer's Disease Degeneration

scientific article published on 12 October 2016

Modulation of hippocampal plasticity and cognitive behavior by short-term blueberry supplementation in aged rats

scientific article

Molecular neuropathogenesis of Alzheimer's disease: an interaction model stressing the central role of oxidative stress

scientific article

Molecular pathogenesis of Alzheimer's disease: reductionist versus expansionist approaches

scientific article published on 26 March 2009

Mutant presenilin 1 increases the expression and activity of BACE1

scientific article published on 05 February 2009

Nanoparticle and other metal chelation therapeutics in Alzheimer disease

scientific article

Nanoparticle delivery of transition-metal chelators to the brain: Oxidative stress will never see it coming!

scientific article

Natural Oxidant Balance in Parkinson Disease

scholarly article by George Perry et al published 1 December 2009 in Archives of Neurology

Neurodegenerative diseases: mechanisms and therapies

scientific article published in January 2006

Neurodegenerative processes in Alzheimer’s disease: an overview of pathogenesis with strategic biomarker potential

Neurofibrillary Tangle Formation as a Protective Response to Oxidative Stress in Alzheimer’s Disease

article

Neurofilamentopathy in neurodegenerative diseases

scientific article published on 26 August 2011

Neurogenesis in Alzheimer’s Disease

Neurogenesis in Human Hippocampus: Implications for Alzheimer Disease Pathogenesis

Neuronal Survival and Death in Alzheimer Disease

Neuronal failure in Alzheimer's disease: a view through the oxidative stress looking-glass

scientific article

Neuronal leptin resistance in Alzheimer's disease

scholarly article by David Bonda et al published July 2013 in Alzheimer's and Dementia

Neuropathology and treatment of Alzheimer disease: did we lose the forest for the trees?

scientific article published on May 2007

Neuropathology in Alzheimer's disease: awaking from a hundred-year-old dream

scientific article published on 3 May 2006

Neuropathology of Alzheimer disease: pathognomonic but not pathogenic

scientific article

Neuroprotective effect of cocoa flavonoids on in vitro oxidative stress

scientific article

Neuroprotective effect of cocoa flavonoids on in vitro oxidative stress

Neuroprotective properties of Bcl-w in Alzheimer disease

scientific article

New Perspectives on Alzheimer's Disease and Nutrition

scientific article published on June 2015

Novel therapeutics for Alzheimer's disease: an update

scientific article

Nuclear and mitochondrial DNA oxidation in Alzheimer's disease

scientific article published on 23 January 2012

O2-04-07 Elevated expression of a regulator of the G2/M phase of the cell cycle, neuronal CIP-1 associated regulator of cyclin B, in Alzheimer disease

Oxidative Adaptation in Aging and Alzheimer’s Disease

Oxidative Damage and Antioxidant Responses in Alzheimer's Disease

article

Oxidative Stress and Alzheimer Disease: Mechanisms and Therapeutic Opportunities

Oxidative Stress and Balance in Neurodegenerative Diseases

Oxidative Stress and Neurodegeneration: An Inevitable Consequence of Aging? Implications for Therapy

article

Oxidative Stress and its Implications for Future Treatments and Management of Alzheimer Disease

scientific article

Oxidative Stress in Alzheimer’s Disease: A Critical Appraisal of the Causes and the Consequences

Oxidative Stress in Parkinson`s Disease

scholarly article by Avi L. Friedlich et al published 20 May 2009 in The open pathology journal

Oxidative damage and Alzheimer's disease: are antioxidant therapies useful?

scientific article

Oxidative damage to RNA in aging and neurodegenerative disorders

scientific article published on 06 June 2012

Oxidative damage to RNA in neurodegenerative diseases

scientific article published in January 2006

Oxidative imbalance in Alzheimer's disease

scientific article

Oxidative stress activates a positive feedback between the gamma- and beta-secretase cleavages of the beta-amyloid precursor protein ⬇️

scientific article

Oxidative stress and mitochondrial dysfunction in Alzheimer's disease

scientific article

Oxidative stress and neurodegeneration

scientific article

Oxidative stress and neuronal adaptation in Alzheimer disease: the role of SAPK pathways

scientific article published on October 2003

Oxidative stress in Alzheimer disease: a possibility for prevention

scientific article published on 13 April 2010

Oxidative stress in diabetes and Alzheimer's disease

scientific article published on January 2009

Oxidative stress signalling in Alzheimer's disease

scientific article published on March 2004

Oxidative stress: the old enemy in Alzheimer's disease pathophysiology

scientific article

P1-266 The critical role of the ERK pathway in the pathogenesis of Alzheimer's disease

scholarly article by Xiongwei Zhu et al published July 2004 in Neurobiology of Aging

P1-351: A novel approach to diagnosis: Antigen-antibody disassociation in Alzheimer's disease

scholarly article by Mark A. Smith et al published July 2008 in Alzheimer's and Dementia

P3-219 Acetylation: a novel posttranslational modification in Alzheimer disease

P3-306 Differential expression of metabotrophic glutamate receptors (MGlurs) in Alzheimer disease

P3-317: Failure in the control of cell cycle causes neurodegeneration

P3-375

P38 activation mediates amyloid-beta cytotoxicity

scientific article published on June 2005

P4-162

P4-166: Overexpression of amyloid precursor protein causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins

PKC inhibition is involved in trichosanthin-induced apoptosis in human chronic myeloid leukemia cell line K562.

scientific article published on 26 July 2006

Parkinson's disease-associated DJ-1 mutations impair mitochondrial dynamics and cause mitochondrial dysfunction

scientific article published on 12 April 2012

Parkinson's disease-associated pathogenic VPS35 mutation causes complex I deficits

scientific article published on 29 July 2017

Pathological implications of cell cycle re-entry in Alzheimer disease

scientific article

Pathological phenotype in familial neurodegenerative disease: implications for families and therapeutic constructs

Pathology's new role: defining disease process and protective responses.

scientific article published in January 2008

Perspectives on the amyloid-beta cascade hypothesis

scientific article published on April 2004

Phosphorylation of tau protein as the link between oxidative stress, mitochondrial dysfunction, and connectivity failure: implications for Alzheimer's disease

scientific article published on 10 July 2013

Physiological regulation of tau phosphorylation during hibernation

scientific article published on June 2008

Posttranslational modifications of α-tubulin in alzheimer disease

scientific article

Presenilin mutation: a deadly first hit in Alzheimer disease. A commentary on "aging sensitizes towards ROS formation and lipid peroxidation in PS1M146L transgenic mice".

scientific article published on 19 January 2006

Presenilin mutations impair mitochondrial dynamics in neurons

Prevention and treatment of Alzheimer disease and aging: antioxidants

scientific article published on February 2007

Prion Protein Protects against Renal Ischemia/Reperfusion Injury

scientific article published on September 2015

Probing and trapping a sensitive conformation: amyloid-β fibrils, oligomers, and dimers

scientific article published in January 2012

Protein Misfolding in Alzheimer's Disease

scholarly article published 3 December 2007

R-_-Lipoic Acid as a Potent Agent of Mitochondrial Protectionin Alzheimer’s Disease

Redox Active Iron at the Center of Oxidative Stress in Alzheimer Disease

article published in 2005

Reexamining Alzheimer's disease: evidence for a protective role for amyloid-beta protein precursor and amyloid-beta

scientific article

Regulation of DJ-1 by Glutaredoxin 1 in Vivo: Implications for Parkinson's Disease

scientific article

Retinoblastoma protein phosphorylation at multiple sites is associated with neurofibrillary pathology in Alzheimer disease.

scientific article published on January 2008

Ribosomal RNA in Alzheimer disease is oxidized by bound redox-active iron

scientific article

Role of Oxidative Insult and Neuronal Survival in Alzheimer’s and Parkinson’s Diseases

scholarly article

Role of metal dyshomeostasis in Alzheimer's disease

scientific article

Role of mitochondrial-mediated signaling pathways in Alzheimer disease and hypoxia

scientific article published on October 2009

S4-02-01 Alzheimer disease: the two hit hypothesis

Sequestration of p27 within the cytoplasm of cardiac myocytes in chronic ischemic heart disease: pathogenic implications for ischemic cardiomyopathy

scientific article published on March 2006

Signal Transduction in Alzheimer’s Disease

article published in 2002

Signal transduction cascades associated with oxidative stress in Alzheimer's disease

scientific article published on May 2007

Signaling effect of amyloid-beta(42) on the processing of AbetaPP

scientific article

Staying connected: synapses in Alzheimer disease

scientific article

Steroidogenic acute regulatory protein (StAR): evidence of gonadotropin-induced steroidogenesis in Alzheimer disease

scientific article

Tau modifiers as therapeutic targets for Alzheimer's disease

scientific article

Tau phosphorylation in Alzheimer's disease: pathogen or protector?

scientific article (publication date: April 2005)

Tau--an inhibitor of deacetylase HDAC6 function

scientific article

The (un)balance between metabolic and oxidative abnormalities and cellular compensatory responses in Alzheimer disease

scientific article

The Key Role of Oxidative Stress in Alzheimer's Disease

scholarly article published 2007

The Potential Application of Antioxidant Agents in Alzheimer Disease Therapeutics

The cell cycle and hormonal fluxes in Alzheimer disease: a novel therapeutic target

scientific article

The cell cycle in Alzheimer disease: a unique target for neuropharmacology

scientific article

The cell cycle regulator phosphorylated retinoblastoma protein is associated with tau pathology in several tauopathies

scientific article

The concept of redox balance in Alzheimer's disease: Mark Anthony Smith 1965–2010

scholarly article by Xiongwei Zhu et al published March 2011 in Redox Report

The earliest stage of cognitive impairment in transition from normal aging to Alzheimer disease is marked by prominent RNA oxidation in vulnerable neurons

scientific article published on March 2012

The effect of mGluR2 activation on signal transduction pathways and neuronal cell survival

scientific article

The essential role of ERK in 4-oxo-2-nonenal-mediated cytotoxicity in SH-SY5Y human neuroblastoma cells

scientific article published on 13 January 2009

The fallacy of amyloid and cognition in Alzheimer's disease

scientific article published in January 2006

The mitochondrial dynamics of Alzheimer's disease and Parkinson's disease offer important opportunities for therapeutic intervention

scientific article published on January 2011

The neuronal expression of MYC causes a neurodegenerative phenotype in a novel transgenic mouse

scientific article published on 22 January 2009

The origin of oxidative stress in neurodegenerative disease: Mark Anthony Smith 1965–2010

The p38 pathway is activated in Pick disease and progressive supranuclear palsy: a mechanistic link between mitogenic pathways, oxidative stress, and tau.

scientific article published in September 2002

The role of E2F1 in the development of hypertrophic cardiomyopathy

scientific article

The role of abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease

scientific article published on May 2009

The role of iron as a mediator of oxidative stress in Alzheimer disease

scientific article published on 23 March 2012

The role of mitogen-activated protein kinase pathways in Alzheimer's disease

scientific article

The rs3756063 polymorphism is associated with SNCA methylation in the Chinese Han population.

scientific article published on 19 May 2016

The sirtuin pathway in ageing and Alzheimer disease: mechanistic and therapeutic considerations

scientific article

Therapeutic opportunities in Alzheimer disease: one for all or all for one?

scientific article

Therapeutic options in Alzheimer's disease

scientific article published on June 2006

Therapeutic potential of oxidant mechanisms in Alzheimer's disease

scientific article

Thinking Outside the Box in Alzheimer Disease Treatment

Tipping the apoptotic balance in Alzheimer's disease: the abortosis concept

scientific article published on January 2003

Transcriptome-To-Metabolome™ Biosimulation Reveals Human Hippocampal Hypometabolism with Age and Alzheimer’s Disease

Treating the lesions, not the disease

scientific article published on May 2007

Treatment advances in Alzheimer's disease based on the oxidative stress model

scientific article

Two Hits and You’re Out? A Novel Mechanistic Hypothesis of Alzheimer Disease

Untangling the vascular web from Alzheimer disease and oxidative stress.

scientific article published in January 2012

Vascular oxidative stress in Alzheimer disease

scientific article

Widespread distribution of reticulon-3 in various neurodegenerative diseases

scientific article

Will Preventing Protein Aggregates Live Up to Its Promise as Prophylaxis Against Neurodegenerative Diseases?

article

Will preventing protein aggregates live up to its promise as prophylaxis against neurodegenerative diseases?

scientific article published on October 2003

c-Jun phosphorylation in Alzheimer disease

scientific article

eIF2alpha phosphorylation tips the balance to apoptosis during osmotic stress

scientific article

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