List of works - Victor M Castillo-Acosta

Carbohydrate-Binding Non-Peptidic Pradimicins for the Treatment of Acute Sleeping Sickness in Murine Models

scientific article

Carbohydrate‐binding agents act as potent trypanocidals that elicit modifications in VSG glycosylation and reduced virulence in Trypanosoma brucei ⬇️

scientific article published on October 14, 2013

Cell cycle regulation and novel structural features of thymidine kinase, an essential enzyme in Trypanosoma brucei

scientific article

Crystal structure and DNA repair activities of the AP endonuclease from Leishmania major

scientific article

Depletion of dimeric all-alpha dUTPase induces DNA strand breaks and impairs cell cycle progression in Trypanosoma brucei.

scientific article published on 5 July 2008

Endogenous sterol biosynthesis is important for mitochondrial function and cell morphology in procyclic forms of Trypanosoma brucei.

scientific article published on 29 August 2012

Exposure of Trypanosoma brucei to an N-acetylglucosamine-binding lectin induces VSG switching and glycosylation defects resulting in reduced infectivity.

scientific article

Identification of a residue critical for the excision of 3'-blocking ends in apurinic/apyrimidinic endonucleases of the Xth family.

scientific article published on 30 January 2009

In vitro antiplasmodial and cytotoxic activities of asymmetrical pyridinium derivatives

scientific article

Increased uracil insertion in DNA is cytotoxic and increases the frequency of mutation, double strand break formation and VSG switching in Trypanosoma brucei.

scientific article

Intracellular location of the early steps of the isoprenoid biosynthetic pathway in the trypanosomatids Leishmania major and Trypanosoma brucei.

scientific article

New azasterols against Trypanosoma brucei: role of 24-sterol methyltransferase in inhibitor action.

scientific article

Pyrimidine requirements in deoxyuridine triphosphate nucleotidohydrolase deficient Trypanosoma brucei mutants.

scientific article published on 29 November 2012

Surface Glycans: A Therapeutic Opportunity for Kinetoplastid Diseases.

scientific article published on 28 July 2017

Surface Glycans: A Therapeutic Opportunity for Kinetoplastid Diseases: (Trends in Parasitology 2017).

scientific article published on 16 October 2017

Trypanosoma brucei AP endonuclease 1 has a major role in the repair of abasic sites and protection against DNA-damaging agents ⬇️

scientific article published on October 29, 2011

Trypanosomes lacking uracil-DNA glycosylase are hypersensitive to antifolates and present a mutator phenotype.

scientific article

List of works by Victor M Castillo-Acosta

Carbohydrate-Binding Non-Peptidic Pradimicins for the Treatment of Acute Sleeping Sickness in Murine Models

Carbohydrate‐binding agents act as potent trypanocidals that elicit modifications in VSG glycosylation and reduced virulence in Trypanosoma brucei ⬇️

Cell cycle regulation and novel structural features of thymidine kinase, an essential enzyme in Trypanosoma brucei

Crystal structure and DNA repair activities of the AP endonuclease from Leishmania major

Depletion of dimeric all-alpha dUTPase induces DNA strand breaks and impairs cell cycle progression in Trypanosoma brucei.

Endogenous sterol biosynthesis is important for mitochondrial function and cell morphology in procyclic forms of Trypanosoma brucei.

Exposure of Trypanosoma brucei to an N-acetylglucosamine-binding lectin induces VSG switching and glycosylation defects resulting in reduced infectivity.

Identification of a residue critical for the excision of 3'-blocking ends in apurinic/apyrimidinic endonucleases of the Xth family.

In vitro antiplasmodial and cytotoxic activities of asymmetrical pyridinium derivatives

Increased uracil insertion in DNA is cytotoxic and increases the frequency of mutation, double strand break formation and VSG switching in Trypanosoma brucei.

Intracellular location of the early steps of the isoprenoid biosynthetic pathway in the trypanosomatids Leishmania major and Trypanosoma brucei.

New azasterols against Trypanosoma brucei: role of 24-sterol methyltransferase in inhibitor action.

Pyrimidine requirements in deoxyuridine triphosphate nucleotidohydrolase deficient Trypanosoma brucei mutants.

Surface Glycans: A Therapeutic Opportunity for Kinetoplastid Diseases.

Surface Glycans: A Therapeutic Opportunity for Kinetoplastid Diseases: (Trends in Parasitology 2017).

Trypanosoma brucei AP endonuclease 1 has a major role in the repair of abasic sites and protection against DNA-damaging agents ⬇️

Trypanosomes lacking uracil-DNA glycosylase are hypersensitive to antifolates and present a mutator phenotype.