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List of works by Rafael Balaña-Fouce

A chronic bioluminescent model of experimental visceral leishmaniasis for accelerating drug discovery

scientific article published on 14 February 2019

A novel active DNA topoisomerase I in Leishmania donovani.

scientific article published on 19 November 2002

A pentapeptide signature motif plays a pivotal role in Leishmania DNA topoisomerase IB activity and camptothecin sensitivity

scientific article published on 18 September 2012

Alterations of the glutathione-redox balance induced by metals in CHO-K1 cells.

scientific article published in July 2002

Alterations on polyamine content and glutathione metabolism induced by different concentrations of paraquat in CHO-K1 cells

scientific article published on 01 June 2000

Analysis of genetic elements regulating the methionine adenosyltransferase gene in Leishmania infantum

article

Antileishmanial activity and tubulin polymerization inhibition of podophyllotoxin derivatives on Leishmania infantum

scientific article published on 28 June 2017

Antileishmanial effect of new indeno-1,5-naphthyridines, selective inhibitors of Leishmania infantum type IB DNA topoisomerase.

scientific article published on 9 September 2016

Aromatic diamidines are reversible inhibitors of porcine kidney diamine oxidase

scientific article published on 01 March 1993

Axenic interspecies and intraclonal hybrid formation in Leishmania: Successful crossings between visceral and cutaneous strains

scientific article published on 09 February 2022

Butyric acid-based feed additives help protect broiler chickens from Salmonella Enteritidis infection.

scientific article

Characterization of the 5' region of the Leishmania infantum LORIEN/MAT2 gene cluster and role of LORIEN flanking regions in post-transcriptional regulation.

scientific article published on 28 March 2008

Current status on prevention and treatment of canine leishmaniasis

scientific article published on 12 July 2016

Cytotoxic effects of two antimolting insecticides in mammalian CHO-K1 cells.

scientific article published in May 2003

DNA topoisomerase I from parasitic protozoa: a potential target for chemotherapy.

scientific article

DNA topoisomerases in apicomplexan parasites: promising targets for drug discovery

scientific article published on 03 March 2010

Deletion study of DNA topoisomerase IB from Leishmania donovani: searching for a minimal functional heterodimer.

scientific article

Drug discovery technologies: Caenorhabditis elegans as a model for anthelmintic therapeutics

scientific article published on 13 March 2020

Early alterations of polyamine metabolism induced after acute administration of clenbuterol in mouse heart

scientific article

Effects of cationic diamidines on polyamine content and uptake on Leishmania infantum in in vitro cultures.

scientific article published in September 1996

Effects of cationic diamidines on polyamine metabolism in the trypanosomatid Crithidia fasciculata

scientific article published on 01 January 1996

First Total Synthesis of -Phenyl 6 Fatty Acids and their Leishmanicidal and Anticancer Properties.

scientific article

First evidence of intraclonal genetic exchange in trypanosomatids using two Leishmania infantum fluorescent transgenic clones

scientific article (publication date: September 2014)

Gene disruption of the DNA topoisomerase IB small subunit induces a non-viable phenotype in the hemoflagellate Leishmania major

scientific article

Gimatecan and other camptothecin derivatives poison Leishmania DNA-topoisomerase IB leading to a strong leishmanicidal effect.

scientific article published in March 2013

In vitro anthelmintic activity and safety of different plant species against the ovine gastrointestinal nematode Teladorsagia circumcincta

scientific article published on 04 January 2019

Inhibition of diamine oxidase and S-adenosylmethionine decarboxylase by diminacene aceturate (berenil)

scientific article published on 01 May 1986

Leishmania donovani methionine adenosyltransferase. Role of cysteine residues in the recombinant enzyme.

scientific article

Leishmania donovani: proteasome-mediated down-regulation of methionine adenosyltransferase

scientific article published on 01 August 2011

Leishmania infantu: Polyamine biosynthesis and levels during the growth of promastigotes ⬇️

scientific article published on 01 January 1991

Mannose-Decorated Dendritic Polyglycerol Nanocarriers Drive Antiparasitic Drugs To Leishmania infantum-Infected Macrophages

scientific article published on 24 September 2020

Molecular and functional characterization of adenylate kinase 2 gene from Leishmania donovani.

scientific article

Muscle and serum changes with salbutamol administration in aerobically exercised rats

scientific article published on 01 May 2000

Mutational analysis of methionine adenosyltransferase from Leishmania donovani.

scientific article

Novel Very Long-Chain α-Methoxylated Δ5,9 Fatty Acids from the Sponge Asteropus niger Are Effective Inhibitors of Topoisomerases IB.

scientific article published on 22 December 2015

PEGylated Dendritic Polyglycerol Conjugate Delivers Doxorubicin to the Parasitophorous Vacuole in Leishmania infantum Infections

scientific article published on 6 July 2017

Plant-based larvicidal agents: An overview from 2000 to 2018

scientific article published on 02 March 2019

Polyamine content and drug sensitivities of different clonal lines of Leishmania infantum promastigotes.

scientific article

Polyamine transport in parasites: a potential target for new antiparasitic drug development.

scientific article

Properties of S-adenosylmethionine decarboxylase from rabbit liver: effects of some hydrazone compounds on its activity.

scientific article published on January 1986

Putrescine uptake inhibition by aromatic diamidines in leishmania infantum promastigotes

scientific article published on 01 May 1994

Putrescine uptake regulation in response to alpha-difluoromethylornithine treatment in Leishmania infantum promastigotes.

scientific article published in October 1991

S -ADENOSYLMETHIONINE SYNTHESIS IN LEISHMANIA INFANTUM PROMASTIGOTES

scientific article published on 01 January 1999

Screening Marine Natural Products for New Drug Leads against Trypanosomatids and Malaria

scientific article published on 31 March 2020

Secreted protein extract analyses present the plant pathogen Alternaria alternata as a suitable industrial enzyme toolbox.

scientific article published on 10 February 2018

Substituted 1,5-naphthyridine derivatives as novel antileishmanial agents. Synthesis and biological evaluation

scientific article published on 18 April 2018

Synthesis and activity of benzopiperidine, benzopyridine and phenyl piperazine based compounds against Leishmania infantum

scientific article published on 18 April 2018

Synthesis and anti-leishmanial evaluation of 1-phenyl-2,3,4,9-tetrahydro-1 H -β-carboline derivatives against Leishmania infantum

scientific article published on 10 August 2016

Synthesis of marine α-methoxylated fatty acid analogs that effectively inhibit the topoisomerase IB from Leishmania donovani with a mechanism different from that of camptothecin

scientific article published on 30 September 2013

Target-based vs. phenotypic screenings in Leishmania drug discovery: A marriage of convenience or a dialogue of the deaf?

scientific article

The Pharmacology of Leishmaniasis ⬇️

scientific article published on April 1, 1998

The first total synthesis of the (±)-17-methyl-trans-4,5-methyleneoctadecanoic acid and related analogs with antileishmanial activity.

scientific article

The intestinal absorption of Luxabendazole in rats

scientific article published on 01 November 1994

Trypanosomatids see the light: recent advances in bioimaging research

scientific article published on 22 September 2014

Trypanosomatids topoisomerase re-visited. New structural findings and role in drug discovery

scientific article

Walking a tightrope: drug discovery in visceral leishmaniasis

scientific article published on 12 March 2019

Yeast-based systems for tropical disease drug discovery

article published in 2016

Zoonotic Implications of Onchocerca Species on Human Health

scientific article published on 17 September 2020

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