List of works by Andrew Bottomley

A European Organisation for Research and Treatment of Cancer phase III trial of adjuvant whole-brain radiotherapy versus observation in patients with one to three brain metastases from solid tumors after surgical resection or radiosurgery: quality-o

scientific article

A critical evaluation of quality of life in clinical trials of breast cancer patients treated with radiation therapy

scientific article published on 24 October 2017

A global analysis of multitrial data investigating quality of life and symptoms as prognostic factors for survival in different tumor sites

A prospective study to validate the Polish language version of the European Organisation for Research and Treatment of Cancer (EORTC) Colorectal Liver Metastases (QLQ-LMC21) module

scientific article published on 31 May 2017

A simulation study provided sample size guidance for differential item functioning (DIF) studies using short scales

scientific article published on 6 September 2008

A systematic review of the quality of statistical methods employed for analysing quality of life data in cancer randomised controlled trials

scientific article

An integrated psychological strategy for advanced colorectal cancer patients

scientific article

An international phase 3 trial in head and neck cancer: quality of life and symptom results: EORTC 24954 on behalf of the EORTC Head and Neck and the EORTC Radiation Oncology Group

scientific article published on 25 October 2013

An international validation study of the EORTC brain cancer module (EORTC QLQ-BN20) for assessing health-related quality of life and symptoms in brain cancer patients

scientific article

Analysing data from patient-reported outcome and quality of life endpoints for cancer clinical trials: a start in setting international standards ⬇️

scientific article

Assessing HRQOL: a neglected issue for high-grade glioma

scientific article published in January 2003

Attitudes of young patients with breast cancer toward fertility loss related to adjuvant systemic therapies. EORTC study 10002 BIG 3-98.

scientific article published on 29 August 2013

Baseline quality of life as a prognostic indicator of survival: a meta-analysis of individual patient data from EORTC clinical trials

scientific article

Beyond the development of health-related quality-of-life (HRQOL) measures: a checklist for evaluating HRQOL outcomes in cancer clinical trials--does HRQOL evaluation in prostate cancer research inform clinical decision making?

scientific article published on September 2003

Clinical and psychometric validation of a questionnaire module, the EORTC QLQ-OG25, to assess health-related quality of life in patients with cancer of the oesophagus, the oesophago-gastric junction and the stomach

scientific article published on 15 August 2007

Comparison of the FACT-C, EORTC QLQ-CR38, and QLQ-CR29 quality of life questionnaires for patients with colorectal cancer: a literature review

scientific article published on 18 May 2016

Comparison of three shortened questionnaires for assessment of quality of life in advanced cancer

scientific article

Corrigendum to “Does a patient’s self-reported health-related quality of life predict survival beyond key biomedical data in advanced colorectal cancer?” [Eur. J. Cancer 42 (2006) 42–49]

article

Cross-cultural development of a quality-of-life measure for patients with melanoma: phase 3 testing of an EORTC Melanoma Module

scientific article

Cross-cultural development of an EORTC questionnaire to assess health-related quality of life in patients with testicular cancer: the EORTC QLQ-TC26

scientific article

Determinants of quality of life in advanced cancer patients with bone metastases undergoing palliative radiation treatment

scientific article published on 19 June 2013

Development of an EORTC quality of life phase III module measuring cancer-related fatigue (EORTC QLQ-FA13).

scientific article

Development, characteristics and validity of the EORTC QLQ-PR25 and the FACT-P for assessment of quality of life in prostate cancer patients

scientific article

Differential item functioning (DIF) analyses of health-related quality of life instruments using logistic regression

scientific article

Differential item functioning (DIF) in the EORTC QLQ-C30: a comparison of baseline, on-treatment and off-treatment data

scientific article

Does a patient's self-reported health-related quality of life predict survival beyond key biomedical data in advanced colorectal cancer?

scientific article

EORTC QLQ-BR23 and FACT-B for the assessment of quality of life in patients with breast cancer: a literature review

scientific article published on January 2015

EORTC QLQ-C15-PAL: the new standard in the assessment of health-related quality of life in advanced cancer?

scientific article published in March 2006

Erythropoietin improves quality of life--a response.

scientific article published in September 2002

Establishing anchor-based minimally important differences (MID) with the EORTC quality-of-life measures: a meta-analysis protocol ⬇️

scientific article published on 10 January 2018

Evaluating health-related quality of life and symptom burden in brain tumour patients: instruments for use in experimental trials and clinical practice

scientific article published on December 2008

Examining the relationships among health-related quality-of-life indicators in cancer patients participating in clinical trials: a pooled study of baseline EORTC QLQ-C30 data

scientific article

Expert Review of Pharmacoeconomics & Outcomes Research: looking forward to a bright future

scientific article published on October 2007

External beam radiotherapy in prostate cancer patients: short- and long-term health-related quality of life issues

scientific article published on August 2003

Factors influencing health related quality of life in cancer patients with bone metastases

scientific article

Fatigue and quality of life: lessons from the real world

scientific article

Group cognitive behavioural therapy: an intervention for cancer patients

scientific article published in July 1996

Guidelines for Inclusion of Patient-Reported Outcomes in Clinical Trial Protocols: The SPIRIT-PRO Extension ⬇️

scientific article published in February 2018

Guidelines for the use of epoetin: have quality-of-life benefits been proven?

scientific article

Health related quality of life in prostate carcinoma patients: a systematic review of randomized controlled trials

scientific article

Health-Related Quality of Life in a Randomized Phase III Study of Bevacizumab, Temozolomide, and Radiotherapy in Newly Diagnosed Glioblastoma

scientific article published on 26 May 2015

Health-related quality of life and cancer

scientific article published in February 2009

Health-related quality of life and cognitive functioning in long-term anaplastic oligodendroglioma and oligoastrocytoma survivors

scientific article published on 26 October 2013

Health-related quality of life and symptom research in glioblastoma multiforme patients

scientific article published on December 2005

Health-related quality of life in locally advanced and metastatic breast cancer: methodological and clinical issues in randomised controlled trials ⬇️

scientific article

Health-related quality of life in non-small-cell lung cancer: an update of a systematic review on methodologic issues in randomized controlled trials

scientific article

Health-related quality of life in non-small-cell lung cancer: methodologic issues in randomized controlled trials

scientific article

Health-related quality of life in patients treated for anaplastic oligodendroglioma with adjuvant chemotherapy: results of a European Organisation for Research and Treatment of Cancer randomized clinical trial

scientific article

Health-related quality of life in patients with brain tumors: limitations and additional outcome measures

scientific article published on July 2013

Health-related quality of life in patients with glioblastoma: a randomised controlled trial

scientific article published on December 2005

Health-related quality of life in patients with high-risk low-grade glioma (EORTC 22033-26033): a randomised, open-label, phase 3 intergroup study

scientific article published on 26 September 2016

Health-related quality of life in small-cell lung cancer: a systematic review on reporting of methods and clinical issues in randomised controlled trials

scientific article published on February 2014

Health-related quality of life in survivors of locally advanced breast cancer: an international randomised controlled phase III trial

scientific article published in May 2005

Health-related quality of life parameters as prognostic factors in a nonmetastatic breast cancer population: an international multicenter study

scientific article

Health-related quality of life with adjuvant ipilimumab versus placebo after complete resection of high-risk stage III melanoma (EORTC 18071): secondary outcomes of a multinational, randomised, double-blind, phase 3 trial

scientific article published on 2 February 2017

Health-related quality-of-life results from PALETTE: A randomized, double-blind, phase 3 trial of pazopanib versus placebo in patients with soft tissue sarcoma whose disease has progressed during or after prior chemotherapy-a European Organization f

scientific article published on 29 May 2015

Human recombinant erythropoietin and quality of life: a wonder drug or something to wonder about?

scientific article

International Psychometric Validation of an EORTC Quality of Life Module Measuring Cancer Related Fatigue (EORTC QLQ-FA12).

scientific article published on May 2017

International field testing of the reliability and validity of the EORTC QLQ-BM22 module to assess health-related quality of life in patients with bone metastases

scientific article published on 11 August 2011

International perspective on health-related quality-of-life research in cancer clinical trials: the European Organisation for Research and Treatment of Cancer experience

scientific article

Interpretation of differential item functioning analyses using external review

scientific article published on June 2010

Is baseline quality of life useful for predicting survival with hormone-refractory prostate cancer? A pooled analysis of three studies of the European Organisation for Research and Treatment of Cancer Genitourinary Group

scientific article

Joint modeling of longitudinal health-related quality of life data and survival

scientific article

Making Advances in Quality of Life Studies in Head and Neck Cancer

scientific article

Making better use of existing cancer data: Patient Reported Outcomes and Behavioural Evidence: a new international initiative.

scientific article published in March 2009

Metastatic colorectal cancer: treatment challenges and quality of life.

scientific article published in May 2002

Minimal important differences for interpreting health-related quality of life scores from the EORTC QLQ-C30 in lung cancer patients participating in randomized controlled trials

scientific article

Moving forward toward standardizing analysis of quality of life data in randomized cancer clinical trials ⬇️

article by Andrew Bottomley et al published December 2018 in Clinical Trials

Moving the boundaries of international collaboration on clinical trials and QoL: experiences in oncology and legislation within the European Parliament

scientific article published in February 2013

Multicollinearity in prognostic factor analyses using the EORTC QLQ-C30: identification and impact on model selection.

scientific article published in December 2002

Net clinical benefit analysis of radiation therapy oncology group 0525: a phase III trial comparing conventional adjuvant temozolomide with dose-intensive temozolomide in patients with newly diagnosed glioblastoma

scientific article published on 07 October 2013

Oral-health-related quality of life in patients with cancer: cultural adaptation and the psychometric testing of the Persian version of EORTC QLQ-OH17.

scientific article published on 15 October 2014

Patient self-reports of symptoms and clinician ratings as predictors of overall cancer survival

scientific article published on 7 December 2011

Patient-Reported Outcomes and Quality of Life with Sunitinib Versus Placebo for Pancreatic Neuroendocrine Tumors: Results From an International Phase III Trial

scientific article published on 6 December 2016

Patient-reported outcomes: assessment and current perspectives of the guidelines of the Food and Drug Administration and the reflection paper of the European Medicines Agency

scientific article

Patients' and health care professionals' evaluation of health-related quality of life issues in bone metastases

scientific article published on 25 July 2009

Predictive factors for overall quality of life in patients with advanced cancer

scientific article published on 22 January 2013

Prognostic value of health-related quality-of-life data in predicting survival in patients with anaplastic oligodendrogliomas, from a phase III EORTC brain cancer group study

scientific article

Promoting pan-European cancer research for the benefit of all cancer patients.

scientific article

Quality of life after palliative radiation therapy for patients with painful bone metastases: results of an international study validating the EORTC QLQ-BM22.

scientific article

Quality of life in breast cancer patients: measurement issues in cancer clinical trials

scientific article published on February 2002

Quality of life in good prognosis patients with metastatic germ cell cancer: a prospective study of the European Organization for Research and Treatment of Cancer Genitourinary Group/Medical Research Council Testicular Cancer Study Group (30941/TE20

scientific article published in March 2003

Quality of life in oncology clinical trials: present and future challenges

scientific article published on April 2002

Quality of life in patients undergoing systemic therapy for advanced breast cancer

scientific article

Radiotherapy in conjunction with intravenous infusion of 180 mg of disodium pamidronate in management of osteolytic metastases from breast cancer: clinical evaluation, biochemical markers, quality of life, and monitoring of recalcification using ass

scientific article published in September 2003

Randomized phase III study of cisplatin with or without raltitrexed in patients with malignant pleural mesothelioma: an intergroup study of the European Organisation for Research and Treatment of Cancer Lung Cancer Group and the National Cancer Inst

scientific article

Review on quality of life issues in patients with primary brain tumors

scientific article published on 27 May 2010

Reviewing back translation reports of questionnaires: the EORTC conceptual framework and experience

scientific article published on 4 October 2017

Short- and long-term HRQOL issues following brachytherapy for prostate cancer

scientific article published on 01 June 2004

Short-term treatment-related symptoms and quality of life: results from an international randomized phase III study of cisplatin with or without raltitrexed in patients with malignant pleural mesothelioma: an EORTC Lung-Cancer Group and National Can

scientific article published on 30 January 2006

Standards are needed for quality of life clinical trials

scientific article

Statistical analysis of patient-reported outcome data in randomised controlled trials of locally advanced and metastatic breast cancer: a systematic review ⬇️

Symptom and quality of life results of an international randomised phase III study of adjuvant vaccination with Bec2/BCG in responding patients with limited disease small-cell lung cancer

scientific article

Symptoms and patient-reported well-being: do they predict survival in malignant pleural mesothelioma? A prognostic factor analysis of EORTC-NCIC 08983: randomized phase III study of cisplatin with or without raltitrexed in patients with malignant pl

scientific article

Systematic Review of the Side Effects Associated With Anti-HER2-Targeted Therapies Used in the Treatment of Breast Cancer, on Behalf of the EORTC Quality of Life Group

scientific article published on 18 December 2015

Systematic review of the side effects associated with tyrosine kinase inhibitors used in the treatment of gastrointestinal stromal tumours on behalf of the EORTC Quality of Life Group

scientific article published on 17 January 2014

The Added Value of Analyzing Pooled Health-Related Quality of Life Data: A Review of the EORTC PROBE Initiative ⬇️

scientific article

The European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire for patients with bone metastases: the EORTC QLQ-BM22.

scientific article published on 25 December 2008

The cancer patient and quality of life

scientific article (publication date: 2002)

The development of the EORTC QLQ-C15-PAL: a shortened questionnaire for cancer patients in palliative care

scientific article published on 12 September 2005

The effects of age on health-related quality of life in cancer populations: A pooled analysis of randomized controlled trials using the European Organisation for Research and Treatment of Cancer (EORTC) QLQ-C30 involving 6024 cancer patients ⬇️

scientific article published on 19 November 2015

The journey of health-related quality of life assessment

scientific article published on September 2008

The practical impact of differential item functioning analyses in a health-related quality of life instrument

scientific article

The process of reconciliation: evaluation of guidelines for translating quality-of-life questionnaires

scientific article

The prognostic significance of patient-reported outcomes in cancer clinical trials

scientific article published on 28 January 2008

The relationship between overall quality of life and its subdimensions was influenced by culture: analysis of an international database

scientific article

The reliability and validity of the Iranian version of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire for patients with Bone Metastases: the EORTC QLQ-BM22

scientific article

The use and impact of quality of life assessment tools in clinical care settings for cancer patients, with a particular emphasis on brain cancer: insights from a systematic review and stakeholder consultations

scientific article

The use of EORTC measures in daily clinical practice-A synopsis of a newly developed manual ⬇️

scientific article

Translation into Portuguese, cross-cultural adaptation and validation of "The European Organization for Research and Treatment of Cancer-Quality of Life Questionnaire-Bone Metastases-22".

scientific article published on 17 June 2016

Translation procedures for standardised quality of life questionnaires: The European Organisation for Research and Treatment of Cancer (EORTC) approach

scientific article published on 03 August 2007

Treatment satisfaction as an outcome measure in cancer clinical treatment trials

scientific article published on December 2002

Trends in translation requests and arising issues regarding cultural adaptation

scientific article (publication date: June 2011)

Understanding the EORTC QLQ-BM22, the module for patients with bone metastases

scientific article

Use of the lung cancer-specific Quality of Life Questionnaire EORTC QLQ-LC13 in clinical trials: A systematic review of the literature 20 years after its development

scientific article published on 09 October 2015

Validation of patient's self-reported social functioning as an independent prognostic factor for survival in metastatic colorectal cancer patients: results of an international study by the Chronotherapy Group of the European Organisation for Researc

scientific article published in April 2008

Validation of the Polish version of the EORTC QLQ-BM22 module for the assessment of health-related quality of life in patients with bone metastases

scientific article

Validation of the Polish version of the EORTC QLQ-OV28 module for the assessment of health-related quality of life in women with ovarian cancer

scientific article

Variability and sample size requirements for health-related quality-of-life measures: understanding the challenges facing investigators

scientific article published in November 2005

What is the effect of systemic anticancer treatment on cognitive function?

scientific article published on May 2004

When a parent has cancer: challenges to patients, their families and health providers

scientific article published on December 2012

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