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List of works by Valentina Pirazzoli

Acquired resistance of EGFR-mutant lung adenocarcinomas to afatinib plus cetuximab is associated with activation of mTORC1.

scientific article

Afatinib plus Cetuximab Delays Resistance Compared to Single-Agent Erlotinib or Afatinib in Mouse Models of TKI-Naïve EGFR L858R-Induced Lung Adenocarcinoma

scientific article

De novo selection of oncogenes

scientific article published on 16 December 2013

Direct evidence of the importance of vitronectin and its interaction with the urokinase receptor in tumor growth ⬇️

scientific article published on January 17, 2013

Endothelial adherens junctions control tight junctions by VE-cadherin-mediated upregulation of claudin-5.

scientific article

Generation of drug-resistant tumors using intermittent dosing of tyrosine kinase inhibitors in mouse

scientific article published in February 2014

HER2 amplification: a potential mechanism of acquired resistance to EGFR inhibition in EGFR-mutant lung cancers that lack the second-site EGFRT790M mutation

scientific article published on 5 September 2012

Next-generation sequencing of paired tyrosine kinase inhibitor-sensitive and -resistant EGFR mutant lung cancer cell lines identifies spectrum of DNA changes associated with drug resistance

scientific article published on 03 June 2013

Noncovalent wild-type-sparing inhibitors of EGFR T790M

scientific article published on 10 December 2012

Oncogenic EGFR Represses the TET1 DNA Demethylase to Induce Silencing of Tumor Suppressors in Cancer Cells

scientific article published on 21 June 2016

Optimizing the sequence of anti-EGFR-targeted therapy in EGFR-mutant lung cancer

scientific article

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