List of works by Josef S Smolen

2010 Rheumatoid arthritis classification criteria: An American College of Rheumatology/European League Against Rheumatism collaborative initiative

scholarly article by Daniel Aletaha et al published 10 August 2010 in Arthritis and Rheumatism

2010 rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative

scientific article

2016 update of the EULAR recommendations for the management of early arthritis ⬇️

scientific article published on 15 December 2016

2019 European League Against Rheumatism/American College of Rheumatology Classification Criteria for Systemic Lupus Erythematosus

scientific article published on 06 August 2019

2019 European League Against Rheumatism/American College of Rheumatology classification criteria for systemic lupus erythematosus

scientific article published on 05 August 2019

A Combination of CD28 (rs1980422) and IRF5 (rs10488631) Polymorphisms Is Associated with Seropositivity in Rheumatoid Arthritis: A Case Control Study

scientific article

A critical evaluation of enzyme immunoassay kits for detection of antinuclear autoantibodies of defined specificities. II. Potential for quantitation of antibody content

scientific article published on 01 January 2002

A critical evaluation of enzyme immunoassay kits for detection of antinuclear autoantibodies of defined specificities. III. Comparative performance characteristics of academic and manufacturers' laboratories.

scientific article published in November 2003

A dynamic real time in vivo and static ex vivo analysis of granulomonocytic cell migration in the collagen-induced arthritis model

scientific article (publication date: 2012)

A framework for remission in SLE: consensus findings from a large international task force on definitions of remission in SLE (DORIS).

scientific article published on 24 November 2016

A patient-derived and patient-reported outcome measure for assessing psoriatic arthritis: elaboration and preliminary validation of the Psoriatic Arthritis Impact of Disease (PsAID) questionnaire, a 13-country EULAR initiative.

scientific article

A pilot risk model for the prediction of rapid radiographic progression in rheumatoid arthritis

scientific article published on 09 July 2009

A randomised, double-blind trial to demonstrate bioequivalence of GP2013 and reference rituximab combined with methotrexate in patients with active rheumatoid arthritis

scientific article published on 21 June 2017

A systematic literature review of drug therapies for the treatment of psoriatic arthritis: current evidence and meta-analysis informing the EULAR recommendations for the management of psoriatic arthritis

scientific article published on 28 July 2011

A1.81 Mincle is not essential in T-cell independent arthritis models

ANA as an Entry Criterion in SLE Classification.

scientific article published on 26 March 2018

AUF1, the regulator of tumor necrosis factor alpha messenger RNA decay, is targeted by autoantibodies of patients with systemic rheumatic diseases

scientific article published in February 2008

Abatacept (CTLA-4Ig) treatment reduces T cell apoptosis and regulatory T cell suppression in patients with rheumatoid arthritis.

scientific article published on 16 December 2015

Aberrant expression of the autoantigen heterogeneous nuclear ribonucleoprotein-A2 (RA33) and spontaneous formation of rheumatoid arthritis-associated anti-RA33 autoantibodies in TNF-alpha transgenic mice

scientific article published on 01 December 2005

Achieving comprehensive disease control in patients with early and established rheumatoid arthritis treated with adalimumab plus methotrexate versus methotrexate alone

scientific article published on 26 September 2017

Activation of the interferon-gamma signaling pathway in systemic lupus erythematosus peripheral blood mononuclear cells

scientific article published in May 2009

Activator protein 1 (Fos/Jun) functions in inflammatory bone and skin disease

scientific article published on 18 January 2008

Activity assessments in rheumatoid arthritis

scientific article published on May 2008

Acute phase reactants add little to composite disease activity indices for rheumatoid arthritis: validation of a clinical activity score

scientific article

Adalimumab - a new TNF-alpha antibody for treatment of inflammatory joint disease

scientific article

Adjustment of therapy in rheumatoid arthritis on the basis of achievement of stable low disease activity with adalimumab plus methotrexate or methotrexate alone: the randomised controlled OPTIMA trial

scientific article

Advances in targeted therapies XIV.

scientific article published in April 2013

Advances in targeted therapy.

scientific article

American College of Rheumatology/European League Against Rheumatism provisional definition of remission in rheumatoid arthritis for clinical trials ⬇️

scientific article

An intergenerational program based on psycho-motor activity promotes well-being and interaction between preschool children and older adults: results of a process and outcome evaluation study in Austria

scientific article published on 01 March 2019

Anti-cofactor autoantibodies in systemic lupus erythematosus: prevalence, clinical and HLA class II associations

scientific article published on 01 January 2008

Anti-hnRNP and other autoantibodies in systemic sclerosis with joint involvement

scientific article

Antiinflammatory effects of tumor necrosis factor on hematopoietic cells in a murine model of erosive arthritis

article

Arthritis induces lymphocytic bone marrow inflammation and endosteal bone formation

scientific article published on 9 February 2004

Aspects of early arthritis. Traditional DMARD therapy: is it sufficient?

scientific article

Assessment of Global Disease Activity in Rheumatoid Arthritis by Patients and Physicians: Differences Across Countries in the METEOR Database

scientific article published on October 2015

Association of anemia and physical disability among patients with rheumatoid arthritis.

scientific article published on 15 October 2007

Association of joint space narrowing with impairment of physical function and work ability in patients with early rheumatoid arthritis: protection beyond disease control by adalimumab plus methotrexate

scientific article published on 22 August 2012

Attainment and characteristics of clinical remission according to the new ACR-EULAR criteria in abatacept-treated patients with early rheumatoid arthritis: new analyses from the Abatacept study to Gauge Remission and joint damage progression in meth

scientific article published on 11 June 2015

Autoantibodies in rheumatoid arthritis and their clinical significance

scientific article

Autoantigen microarrays for multiplex characterization of autoantibody responses

scientific article

B-cell infiltrates induce endosteal bone formation in inflammatory arthritis.

scientific article published in October 2008

B-cell targeted therapeutics in clinical development

scientific article published on 04 April 2013

Baricitinib in Patients with Refractory Rheumatoid Arthritis

scientific article

Benefits and Sustainability of a Learning Collaborative for Implementation of Treat to Target in Rheumatoid Arthritis: Results of the TRACTION Trial Phase II.

scientific article

Biosimilar safety factors in clinical practice

scientific article

Biosimilars to treat inflammatory arthritis: the challenge of proving identity

scientific article published on 29 July 2013

Blocking the effects of interleukin-6 in rheumatoid arthritis and other inflammatory rheumatic diseases: systematic literature review and meta-analysis informing a consensus statement

scientific article

Bone erosions and bone marrow edema as defined by magnetic resonance imaging reflect true bone marrow inflammation in rheumatoid arthritis

scientific article

Brief Report: Remission Rates With Tofacitinib Treatment in Rheumatoid Arthritis: A Comparison of Various Remission Criteria

scientific article published on December 2016

CCR6 controls autoimmune but not innate immunity-driven experimental arthritis

scientific article published on 22 August 2018

CD44 is a determinant of inflammatory bone loss

scientific article

CD4⁺CD25⁻Foxp3⁺ T cells: a marker for lupus nephritis?

scientific article

CD55 deposited on synovial collagen fibers protects from immune complex-mediated arthritis

scientific article published on 17 January 2015

Cadherin 11 promotes invasive behavior of fibroblast-like synoviocytes

scientific article published on May 2009

Can we improve the performance and reporting of investigator-initiated clinical trials? Rheumatoid arthritis as an example

scientific article

Certolizumab pegol plus methotrexate 5-year results from the rheumatoid arthritis prevention of structural damage (RAPID) 2 randomized controlled trial and long-term extension in rheumatoid arthritis patients

scientific article

Certolizumab pegol plus methotrexate provides broad relief from the burden of rheumatoid arthritis: analysis of patient-reported outcomes from the RAPID 2 trial

scientific article

Changes in patient characteristics in anti-tumour necrosis factor clinical trials for rheumatoid arthritis: results of an analysis of the literature over the past 16 years

scientific article published on 27 June 2011

Clinical meaning and implications of serum hemoglobin levels in patients with rheumatoid arthritis

scientific article

Clinical trials of new drugs for the treatment of rheumatoid arthritis: focus on early disease

scientific article

Clinical, functional and radiographic consequences of achieving stable low disease activity and remission with adalimumab plus methotrexate or methotrexate alone in early rheumatoid arthritis: 26-week results from the randomised, controlled OPTIMA s

scientific article published on 5 May 2012

Clocking in: chronobiology in rheumatoid arthritis

scientific article published on 24 March 2015

Combination of infliximab and methotrexate therapy for early rheumatoid arthritis: a randomized, controlled trial

scientific article

Comorbidity affects all domains of physical function and quality of life in patients with rheumatoid arthritis ⬇️

scientific article published on October 29, 2010

Comparative effectiveness and safety of biological treatment options after tumour necrosis factor α inhibitor failure in rheumatoid arthritis: systematic review and indirect pairwise meta-analysis

scientific article published on 30 January 2012

Comparing biosimilar SB2 with reference infliximab after 54 weeks of a double-blind trial: clinical, structural and safety results

scientific article published in October 2017

Comparison of employability outcomes among patients with early or long-standing rheumatoid arthritis

scientific article published on 01 April 2008

Consensus statement on blocking the effects of interleukin-6 and in particular by interleukin-6 receptor inhibition in rheumatoid arthritis and other inflammatory conditions

scientific article published on 21 November 2012

Contribution of Genetic Factors to Lower DHEAS in Patients with Rheumatoid Arthritis

scientific article published on 15 July 2017

Contributions of ultrasound beyond clinical data in assessing inflammatory disease activity in rheumatoid arthritis: current insights and future prospects

scientific article

Conversion to seronegative status after abatacept treatment in patients with early and poor prognostic rheumatoid arthritis is associated with better radiographic outcomes and sustained remission: post hoc analysis of the AGREE study. ⬇️

scientific article published on 30 March 2018

Correction: Interleukin-6: a new therapeutic target.

scientific article published on 17 October 2006

Criteria for early rheumatoid arthritis: from Bayes' law revisited to new thoughts on pathogenesis

scientific article

Current evidence for the management of rheumatoid arthritis with synthetic disease-modifying antirheumatic drugs: a systematic literature review informing the EULAR recommendations for the management of rheumatoid arthritis

scientific article

Cytokines as therapeutic targets: advances and limitations

scientific article published on April 2008

Daily functioning and health status in patients with hand osteoarthritis: Fewer differences between women and men than expected

scientific article published in October 2011

Definition of treatment response in rheumatoid arthritis based on the simplified and the clinical disease activity index

scientific article

Determinants of Patient-Physician Discordance in Global Assessment in Psoriatic Arthritis: A Multicenter European Study

scientific article published on 20 December 2016

Determinants of sleep impairment in psoriatic arthritis: an observational study with 396 patients from 14 countries

scientific article published on 10 April 2020

Determination of Autoantibody Isotypes Increases the Sensitivity of Serodiagnostics in Rheumatoid Arthritis.

scientific article

Developing an effective treatment algorithm for rheumatoid arthritis

scientific article published on July 2012

Developing and Refining New Candidate Criteria for Systemic Lupus Erythematosus Classification: An International Collaboration

scientific article published on 10 July 2017

Development and validation of modified disease activity scores in rheumatoid arthritis: superior correlation with magnetic resonance imaging-detected synovitis and radiographic progression

scientific article published in April 2014

Development of EULAR recommendations for the reporting of clinical trial extension studies in rheumatology ⬇️

scientific article published on 14 May 2014

Development of a multimorbidity index: Impact on quality of life using a rheumatoid arthritis cohort

scientific article

Development of a new occupational balance-questionnaire: incorporating the perspectives of patients and healthy people in the design of a self-reported occupational balance outcome instrument

scientific article published on 05 April 2014

Development of patient-centred standards of care for osteoarthritis in Europe: the eumusc.net-project

scientific article

Development of patient-centred standards of care for rheumatoid arthritis in Europe: the eumusc.net project

scientific article published on 06 August 2013

Developments in the clinical understanding of rheumatoid arthritis

scientific article published on 30 January 2009

Diagnosis and Management of Rheumatoid Arthritis: A Review

scientific article published in The Journal of the American Medical Association

Dickkopf-1 is a master regulator of joint remodeling

scientific article published on 21 January 2007

Differential tissue expression and activation of p38 MAPK alpha, beta, gamma, and delta isoforms in rheumatoid arthritis

scientific article published on September 2006

Differentially regulated expression of growth differentiation factor 5 and bone morphogenetic protein 7 in articular cartilage and synovium in murine chronic arthritis: potential importance for cartilage breakdown and synovial hypertrophy

scientific article

Discordance between patient and physician assessments of global disease activity in rheumatoid arthritis and association with work productivity

scientific article published on 21 May 2016

Disease activity and response assessment in psoriatic arthritis using the Disease Activity index for PSoriatic Arthritis (DAPSA). A brief review

scientific article published on 15 October 2015

Disease activity improvements with optimal discriminatory ability between treatment arms: applicability in early and established rheumatoid arthritis clinical trials

scientific article published on 10 November 2019

Disease activity in psoriatic arthritis (PsA): defining remission and treatment success using the DAPSA score

scientific article published on 12 August 2015

Disruption of the interaction of T cells with antigen-presenting cells by the active leflunomide metabolite teriflunomide: Involvement of impaired integrin activation and immunologic synapse formation

scientific article (publication date: 2005)

Do patient-reported outcome measures cover personal factors important to people with rheumatoid arthritis? A mixed methods design using the International Classification of Functioning, Disability and Health as frame of reference

scientific article

Documentation of off-label use of biologics in Rheumatoid Arthritis

scientific article published on April 2013

Does mixed connective tissue disease exist? Yes

scientific article

ESCMID Study Group for Infections in Compromised Hosts (ESGICH) Consensus Document on the safety of targeted and biological therapies: an Infectious Diseases perspective (Soluble immune effector molecules [II]: agents targeting interleukins, immunog

scientific article published on 12 February 2018

EULAR Sjögren's syndrome disease activity index (ESSDAI): a user guide

scientific article

EULAR definition of erosive disease in light of the 2010 ACR/EULAR rheumatoid arthritis classification criteria

scientific article

EULAR recommendations for terminology and research in individuals at risk of rheumatoid arthritis: report from the Study Group for Risk Factors for Rheumatoid Arthritis

scientific article published on 2 March 2012

EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs

scientific article

EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2013 update

scientific article

EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2016 update ⬇️

scientific article published on 6 March 2017

EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2019 update

scientific article published on 22 January 2020

EULAR recommendations for the use of imaging of the joints in the clinical management of rheumatoid arthritis

scientific article published on 21 March 2013

Early structural changes in cartilage and bone are required for the attachment and invasion of inflamed synovial tissue during destructive inflammatory arthritis.

scientific article published on 18 January 2012

Economic aspects of treatment options in rheumatoid arthritis: a systematic literature review informing the EULAR recommendations for the management of rheumatoid arthritis

scientific article published on 06 May 2010

Effect of adalimumab on the work-related outcomes scores in patients with early rheumatoid arthritis receiving methotrexate

scientific article

Effect of certolizumab pegol with methotrexate on home and work place productivity and social activities in patients with active rheumatoid arthritis

scientific article

Effect of interleukin-6 receptor inhibition with tocilizumab in patients with rheumatoid arthritis (OPTION study): a double-blind, placebo-controlled, randomised trial.

scientific article

Effectiveness profiles and dose dependent retention of traditional disease modifying antirheumatic drugs for rheumatoid arthritis. An observational study.

scientific article published on August 2002

Effects of 18β-Glycyrrhetinic acid in hTNFtg mice - a model of rheumatoid arthritis

scientific article

Effects of a brief workplace-centered consultation for employees with musculoskeletal pain on health outcomes: a prospective cohort study

article

Efficacy and Safety of ABT-494, a Selective JAK-1 Inhibitor, in a Phase IIb Study in Patients With Rheumatoid Arthritis and an Inadequate Response to Methotrexate

scientific article

Efficacy and safety of an interleukin 6 monoclonal antibody for the treatment of systemic lupus erythematosus: a phase II dose-ranging randomised controlled trial

scientific article

Efficacy and safety of tabalumab, an anti-B-cell-activating factor monoclonal antibody, in patients with rheumatoid arthritis who had an inadequate response to methotrexate therapy: results from a phase III multicentre, randomised, double-blind stud

scientific article

Efficacy and safety of tofacitinib monotherapy, tofacitinib with methotrexate, and adalimumab with methotrexate in patients with rheumatoid arthritis (ORAL Strategy): a phase 3b/4, double-blind, head-to-head, randomised controlled trial

scientific article published on 15 June 2017

Efficacy of biological disease-modifying antirheumatic drugs: a systematic literature review informing the 2013 update of the EULAR recommendations for the management of rheumatoid arthritis

scientific article published on 07 January 2014

Efficacy of biological disease-modifying antirheumatic drugs: a systematic literature review informing the 2016 update of the EULAR recommendations for the management of rheumatoid arthritis

scientific article published on 10 March 2017

Efficacy of conventional synthetic disease-modifying antirheumatic drugs, glucocorticoids and tofacitinib: a systematic literature review informing the 2013 update of the EULAR recommendations for management of rheumatoid arthritis

scientific article

Efficacy of glucocorticoids, conventional and targeted synthetic disease-modifying antirheumatic drugs: a systematic literature review informing the 2016 update of the EULAR recommendations for the management of rheumatoid arthritis

scientific article published on 29 March 2017

Efficacy outcomes in phase 2 and phase 3 randomized controlled trials in rheumatology

scientific article published on 20 April 2020

Endothelial precursor cells in the synovial tissue of patients with rheumatoid arthritis and osteoarthritis

scientific article

Endothelial progenitor cells in active rheumatoid arthritis: effects of tumour necrosis factor and glucocorticoid therapy

scientific article

Environmental arginine controls multinuclear giant cell metabolism and formation

scientific article published on 22 January 2020

Era of biosimilars in rheumatology: reshaping the healthcare environment.

scientific article published on 21 May 2019

Essential role of microRNA-155 in the pathogenesis of autoimmune arthritis in mice

scientific article published on 01 May 2011

Estimation of a numerical value for joint damage-related physical disability in rheumatoid arthritis clinical trials

scientific article published on 27 August 2009

Estrogen-dependent and C-C chemokine receptor-2-dependent pathways determine osteoclast behavior in osteoporosis.

scientific article published on 29 March 2009

Evidence for predictive validity of remission on long-term outcome in rheumatoid arthritis: a systematic review

scientific article

Evidence for treating rheumatoid arthritis to target: results of a systematic literature search

scientific article published on April 2010

Evidence for treating rheumatoid arthritis to target: results of a systematic literature search update ⬇️

scientific article published on 19 May 2015

Existing joint erosions increase the risk of joint space narrowing independently of clinical synovitis in patients with early rheumatoid arthritis

scientific article published on 21 May 2015

Expanding the frontiers of therapy

scientific article

Follow-up standards and treatment targets in rheumatoid arthritis: results of a questionnaire at the EULAR 2008.

scientific article published on 22 April 2009

Forget personalised medicine and focus on abating disease activity

scientific article

Future of RA: building on what we know and tailoring treatment.

scientific article published in July 2012

GRAPPA-OMERACT consensus-based recommendations and research agenda for use of composite measures and treatment targets in PsA. ⬇️

scientific article published on 28 November 2017

Gait changes precede overt arthritis and strongly correlate with symptoms and histopathological events in pristane-induced arthritis

scientific article

Glucocorticoid Effect on Radiographic Progression in Placebo Arms of Rheumatoid Arthritis Biologics Trials

scientific article published on April 2016

Golimumab in patients with active rheumatoid arthritis after treatment with tumor necrosis factor α inhibitors: findings with up to five years of treatment in the multicenter, randomized, double-blind, placebo-controlled, phase 3 GO-AFTER study

scientific article published on 22 January 2015

Golimumab in patients with active rheumatoid arthritis after treatment with tumour necrosis factor alpha inhibitors (GO-AFTER study): a multicentre, randomised, double-blind, placebo-controlled, phase III trial

scientific article

Golimumab in patients with active rheumatoid arthritis who have previous experience with tumour necrosis factor inhibitors: results of a long-term extension of the randomised, double-blind, placebo-controlled GO-AFTER study through week 160

scientific article

Greetings from the editor 2021

scientific article published on 01 January 2021

HLA class II DNA typing in a large series of European patients with systemic lupus erythematosus: correlations with clinical and autoantibody subsets

scientific article published on 01 May 2002

Head-to-head comparison of certolizumab pegol versus adalimumab in rheumatoid arthritis: 2-year efficacy and safety results from the randomised EXXELERATE study

scientific article published on 11 November 2016

Health determining concepts important to people with Crohn's disease and their coverage by patient-reported outcomes of health and wellbeing

scientific article published on 31 January 2013

Heterologous vector versus homologous mRNA COVID-19 booster vaccination in non-seroconverted immunosuppressed patients: a randomized controlled trial

scientific article published in 2022

Histopathological correlation supports the use of x-rays in the diagnosis of hand osteoarthritis

scientific article published on 12 May 2012

Historical observations contributing insights on etiopathogenesis of rheumatoid arthritis and role of rheumatoid factor.

scientific article published on 12 September 2016

How to report radiographic data in randomized clinical trials in rheumatoid arthritis: guidelines from a roundtable discussion

scientific article

I have mastered the challenge of living with a chronic disease: life stories of people with rheumatoid arthritis

scientific article

Identification of relevant concepts of functioning in daily life in people with systemic lupus erythematosus: A patient Delphi exercise

scientific article published on 01 January 2009

Identifying Provisional Generic Contextual Factor Domains for Clinical Trials in Rheumatology: Results from an OMERACT Initiative

scientific article published on 15 January 2019

IgG and IgM anticardiolipin antibodies following treatment with infliximab plus methotrexate in patients with early rheumatoid arthritis

scientific article published on 01 September 2006

Imbalance of local bone metabolism in inflammatory arthritis and its reversal upon tumor necrosis factor blockade: direct analysis of bone turnover in murine arthritis

scientific article published on January 2006

Immediate access rheumatology clinic: efficiency and outcomes

scientific article published on 11 October 2011

Immunodominant T-cell epitopes of hnRNP-A2 associated with disease activity in patients with rheumatoid arthritis.

scientific article published in June 2010

Impact of Treatment-Related Beliefs on Medication Adherence in Immune-Mediated Inflammatory Diseases: Results of the Global ALIGN Study

scientific article

Impact of tocilizumab administered intravenously or subcutaneously on patient-reported quality-of-life outcomes in patients with rheumatoid arthritis.

scientific article

Impairment of chondrocyte biosynthetic activity by exposure to 3-tesla high-field magnetic resonance imaging is temporary

scientific article published on January 2006

Implementation of Treat-to-Target in Rheumatoid Arthritis Through a Learning Collaborative: Results of a Randomized Controlled Trial

scientific article published on 17 May 2017

Implementation of treat-to-target in rheumatoid arthritis through a Learning Collaborative: Rationale and design of the TRACTION trial

scientific article published on 8 March 2016

Incomplete lupus erythematosus: results of a multicentre study under the supervision of the EULAR Standing Committee on International Clinical Studies Including Therapeutic Trials (ESCISIT)

Increased expression of discoidin domain receptor 2 is linked to the degree of cartilage damage in human knee joints: a potential role in osteoarthritis pathogenesis

scientific article published on 01 November 2007

Induction of sustained remission in early inflammatory arthritis with the combination of infliximab plus methotrexate: the DINORA trial

Inflammatory bone loss: pathogenesis and therapeutic intervention

scientific article published on March 2012

Infliximab in active early rheumatoid arthritis

scientific article published on February 2004

Infliximab: 12 years of experience

scientific article

Information technology in rheumatology

scientific article

Inhibition of interleukin-6 receptor directly blocks osteoclast formation in vitro and in vivo

scientific article

Initial evidence for the link between activities and health: Associations between a balance of activities, functioning and serum levels of cytokines and C-reactive protein

scientific article published on 21 December 2015

Insights into the efficacy of golimumab plus methotrexate in patients with active rheumatoid arthritis who discontinued prior anti-tumour necrosis factor therapy: post-hoc analyses from the GO-AFTER study

scientific article

Interaction between synovial inflammatory tissue and bone marrow in rheumatoid arthritis.

scientific article published in August 2005

Interferon signals and monocytic sensitization of the interferon-γ signaling pathway in the peripheral blood of patients with rheumatoid arthritis.

scientific article

Interleukin 6 is not a crucial regulator in an animal model of tumour necrosis factor-mediated bilateral sacroiliitis

scientific article published on 24 May 2010

Interleukin-6: a new therapeutic target

scientific article

Interphalangeal Osteoarthritis Radiographic Simplified (iOARS) score: a radiographic method to detect osteoarthritis of the interphalangeal finger joints based on its histopathological alterations.

scientific article

Is adalimumab in combination with methotrexate a safe and efficacious treatment for early rheumatoid arthritis?

scientific article

Is computer-assisted management necessary for patients with early rheumatoid arthritis?

scientific article

JNK1 is not essential for TNF-mediated joint disease

scientific article

Joint damage in rheumatoid arthritis progresses in remission according to the Disease Activity Score in 28 joints and is driven by residual swollen joints

scientific article

Leflunomide: a manageable safety profile.

scientific article published on June 2004

Lefunomide in combination therapy.

scientific article published on June 2004

Listeria-associated arthritis in a patient undergoing etanercept therapy: case report and review of the literature

scientific article

Long-Term Radiographic and Patient-Reported Outcomes in Patients with Rheumatoid Arthritis Treated with Tofacitinib: ORAL Start and ORAL Scan Post-hoc Analyses.

scientific article

Longterm safety and efficacy of tocilizumab in patients with rheumatoid arthritis: a cumulative analysis of up to 4.6 years of exposure

scientific article published on March 2013

Management of psoriatic arthritis in 2016: a comparison of EULAR and GRAPPA recommendations

scientific article published on 10 November 2016

Mapping hand functioning in hand osteoarthritis: comparing self-report instruments with a comprehensive hand function test

scientific article published on 01 October 2007

Measuring function in rheumatoid arthritis: Identifying reversible and irreversible components

scientific article

Measuring functioning in patients with hand osteoarthritis--content comparison of questionnaires based on the International Classification of Functioning, Disability and Health (ICF).

scientific article published on 2 May 2006

Measuring health in patients with fibromyalgia: content comparison of questionnaires based on the International Classification of Functioning, Disability and Health

scientific article published on May 2008

Mechanisms of Disease: the link between RANKL and arthritic bone disease

scientific article published on November 2005

Mechanisms of tissue damage in arthritis

scientific article published on 12 September 2014

Methotrexate in rheumatoid arthritis is frequently effective, even if re-employed after a previous failure

scientific article

Minimal disease activity for rheumatoid arthritis: a preliminary definition

scientific article

Mixed connective tissue disease: what is behind the curtain?

scientific article published on December 2007

Moberg picking-up test in patients with inflammatory joint diseases: a survey of suitability in comparison with button test and measures of disease activity

scientific article published on 01 October 2003

Monitoring rheumatoid arthritis

scientific article published on May 2011

Multicriteria decision analysis process to develop new classification criteria for systemic lupus erythematosus

scientific article published on 28 January 2019

Multimorbidity and rheumatic conditions-enhancing the concept of comorbidity

scientific article published on 14 January 2014

New GRAPPA and EULAR recommendations for the management of psoriatic arthritis. ⬇️

scientific article published on 11 January 2017

New insights in the mechanism of bone loss in arthritis

scientific article

New therapies for treatment of rheumatoid arthritis

scientific article published on December 2007

Objectives and strategies for rheumatoid arthritis therapy: yesterday vs. today.

scientific article published on January 2003

Occupational balance of women with rheumatoid arthritis: a qualitative study.

scientific article published in January 2004

Opportunities and challenges in rheumatology research in Central Europe

scientific article published on 4 September 2017

Osteoclasts are essential for TNF-alpha-mediated joint destruction

scientific article

Osteoprotegerin is a risk factor for progressive atherosclerosis and cardiovascular disease

scientific article published on 26 April 2004

Osteoprotegerin protects against generalized bone loss in tumor necrosis factor-transgenic mice

scientific article published in July 2003

Overexpression of tumor necrosis factor causes bilateral sacroiliitis

scientific article published in March 2004

PTEN in antigen presenting cells is a master regulator for Th17-mediated autoimmune pathology

scientific article published on 9 February 2012

Pathogenesis of rheumatoid arthritis: targeting cytokines

scientific article

Pathogenetic aspects of systemic lupus erythematosus with an emphasis on regulatory T cells

scientific article published on 16 July 2010

Patient access to rheumatoid arthritis treatments

scientific article published on 01 January 2008

Patient education, disease activity and physical function: can we be more targeted? A cross sectional study among people with rheumatoid arthritis, psoriatic arthritis and hand osteoarthritis ⬇️

scientific article published on 20 October 2013

Patient global assessment in psoriatic arthritis - what does it mean? An analysis of 223 patients from the Psoriatic arthritis impact of disease (PsAID) study

scientific article published on 8 December 2015

Patient perspective on remission in rheumatoid arthritis

scientific article published in August 2011

Perceptions of risk and predictive testing held by the first-degree relatives of patients with rheumatoid arthritis in England, Austria and Germany: a qualitative study

scientific article published on 29 June 2016

Performance of Anti-nuclear Antibodies for Classifying Systemic Lupus Erythematosus: a Systematic Literature Review and Meta-regression of Diagnostic Data

scientific article

Performance of the 2010 ACR/EULAR classification criteria for rheumatoid arthritis: a systematic literature review

scientific article published on 16 April 2013

Performance of the 2019 EULAR/ACR classification criteria for systemic lupus erythematosus in early disease, across sexes and ethnicities

scientific article published on 14 August 2020

Pharmacological management of early rheumatoid arthritis--does combination therapy improve outcomes?

scientific article

Pharmacological treatment of psoriatic arthritis: a systematic literature research for the 2019 update of the EULAR recommendations for the management of psoriatic arthritis

scientific article published on 07 May 2020

Pharmacological treatment of psoriatic arthritis: a systematic literature review for the 2015 update of the EULAR recommendations for the management of psoriatic arthritis

scientific article

Pharmacotherapy: How well can we compare different biologic agents for RA?

scientific article published on May 2010

Phenotypic and functional analysis of CD4+ CD25- Foxp3+ T cells in patients with systemic lupus erythematosus

scientific article published in February 2009

Phosphatase and tensin homolog (PTEN) in antigen-presenting cells controls Th17-mediated autoimmune arthritis

scientific article published on 26 August 2015

Physical disability in rheumatoid arthritis is associated with cartilage damage rather than bone destruction

scientific article

Physical function and health related quality of life: analysis of 2-year data from randomized, controlled studies of leflunomide, sulfasalazine, or methotrexate in patients with active rheumatoid arthritis

scientific article

Physical function continues to improve when clinical remission is sustained in rheumatoid arthritis patients

scientific article published on 11 August 2015

Points to consider for the treatment of immune-mediated inflammatory diseases with Janus kinase inhibitors: a consensus statement

scientific article published on 06 November 2020

Pooled analysis of TNF inhibitor biosimilar studies comparing radiographic progression by disease activity states in rheumatoid arthritis

scientific article published on 01 January 2020

Possible discontinuation of therapies in inflammatory rheumatic diseases - as with initiation of therapies, a shared decision between patient and rheumatologist.

scientific article

Predicting adherence to therapy in rheumatoid arthritis, psoriatic arthritis or ankylosing spondylitis: a large cross-sectional study

scholarly article by Josef S Smolen et al published 2019 in RMD open

Predictors for influenza vaccine acceptance among patients with inflammatory rheumatic diseases

scholarly article by Nicole Harrison et al published August 2018 in Vaccine

Predictors of disease activity and structural progression after treatment with adalimumab plus methotrexate or continued methotrexate monotherapy in patients with early rheumatoid arthritis and suboptimal response to methotrexate

scholarly article by Josef S Smolen et al published November 2018 in Annals of the Rheumatic Diseases

Predictors of remission with etanercept-methotrexate induction therapy and loss of remission with etanercept maintenance, reduction, or withdrawal in moderately active rheumatoid arthritis: results of the PRESERVE trial

scientific article published on 16 January 2018

Prevalence and validity of ACR/EULAR remission in four European early rheumatoid arthritis cohorts.

scientific article published on 26 February 2018

Prevalence of comorbidities in rheumatoid arthritis and evaluation of their monitoring: results of an international, cross-sectional study (COMORA).

scientific article published on 04 October 2013

Pro-inflammatory cytokines in rheumatoid arthritis: pathogenetic and therapeutic aspects

scientific article

Progress toward the development of a new definition of remission in rheumatoid arthritis

scientific article published on 01 January 2010

Proposal for a new nomenclature of disease-modifying antirheumatic drugs

scientific article published on 26 September 2013

Putting patients first: the need for evidence-based and patient-centered standards of care in rheumatoid arthritis

article

Quality indicators in rheumatoid arthritis: results from the METEOR database

scientific article

Quantitative and qualitative deficiencies of regulatory T cells in patients with systemic lupus erythematosus (SLE).

scientific article published on 9 May 2008

Radiographic progression based on baseline characteristics from TNF inhibitor biosimilar studies in patients with rheumatoid arthritis

scientific article published on 14 August 2020

Recommendations for an update of 2003 European regulatory requirements for registration of drugs to be used in the treatment of RA.

scientific article

Regulatory T cell-deficient scurfy mice develop systemic autoimmune features resembling lupus-like disease

scientific article

Regulatory T cells form stable and long-lasting cell cluster with myeloid dendritic cells (DC).

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Relationship between disease activity indices and their individual components and radiographic progression in RA: a systematic literature review

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Relevant concepts of functioning for patients with systemic lupus erythematosus identified in a Delphi exercise of experts and a literature review

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Reliability of patient-reported outcomes in rheumatoid arthritis patients: an observational prospective study

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Remission and active disease in rheumatoid arthritis: defining criteria for disease activity states

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Remission by composite scores in rheumatoid arthritis: are ankles and feet important?

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Remission in Rheumatoid Arthritis: Working Toward Incorporation of the Patient Perspective at OMERACT 12.

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Remission in early rheumatoid arthritis defined by 28 joint counts: limited consequences of residual disease activity in the forefeet on outcome

scientific article published on 27 September 2011

Remission in rheumatoid arthritis: benefit over low disease activity in patient-reported outcomes and costs

scientific article published on 21 February 2014

Remission in rheumatoid arthritis: missing objectives by using inadequate DAS28 targets

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Repair of local bone erosions and reversal of systemic bone loss upon therapy with anti-tumor necrosis factor in combination with osteoprotegerin or parathyroid hormone in tumor necrosis factor-mediated arthritis

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Reply

scholarly article

Reporting of long-term extension studies: lack of consistency calls for consensus

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Research in hand osteoarthritis: time for reappraisal and demand for new strategies. An opinion paper

scientific article published on 14 March 2007

Response of elderly patients with rheumatoid arthritis to methotrexate or TNF inhibitors compared with younger patients

scientific article published on 7 October 2009

Response to 'Feasibility of tailored treatment based on risk stratification in patients with early rheumatoid arthritis'.

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Response to baricitinib based on prior biologic use in patients with refractory rheumatoid arthritis

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Response to: 'The time has come to revisit alternative interpretations of data underlying the EULAR management recommendations for rheumatoid arthritis' by Pirilä et al.

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Rheumatoid arthritis and falls: the influence of disease activity

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Rheumatoid arthritis in 2010: from the gut to the joint

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Rheumatoid arthritis near remission: clinical rather than laboratory inflammation is associated with radiographic progression

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Rheumatoid arthritis therapy after tumor necrosis factor and interleukin-1 blockade

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Rheumatoid arthritis therapy reappraisal: strategies, opportunities and challenges

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Rheumatoid arthritis.

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Rheumatoid arthritis: where are we now?

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Rheumatoid factor determines structural progression of rheumatoid arthritis dependent and independent of disease activity

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Rheumatoid factor, not antibodies against citrullinated proteins, is associated with baseline disease activity in rheumatoid arthritis clinical trials

scientific article published on 26 August 2015

Rituximab dissociates the tight link between disease activity and joint damage in rheumatoid arthritis patients

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SLE - Complex cytokine effects in a complex autoimmune disease: tumor necrosis factor in systemic lupus erythematosus

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Safety and efficacy of baricitinib in elderly patients with rheumatoid arthritis

scientific article published on 10 October 2017

Safety and efficacy of biosimilars in oncology

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Safety and efficacy of tumor necrosis factor alpha blockade in systemic lupus erythematosus: an open-label study

scientific article published in October 2004

Safety of off-label biologicals in systemic lupus erythematosus

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Safety of synthetic and biological DMARDs: a systematic literature review informing the 2013 update of the EULAR recommendations for management of rheumatoid arthritis

scientific article published on 08 January 2014

Safety of synthetic and biological DMARDs: a systematic literature review informing the 2016 update of the EULAR recommendations for management of rheumatoid arthritis

scientific article published on 15 March 2017

Serological changes in the course of traditional and biological disease modifying therapy of rheumatoid arthritis

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Serum leptin level and the risk of nontraumatic fracture

scientific article published in December 2004

Similar problem in the activities of daily living but different experience: a qualitative analysis in six rheumatic conditions and eight European countries

scientific article published on 30 January 2013

Single and combined inhibition of tumor necrosis factor, interleukin-1, and RANKL pathways in tumor necrosis factor-induced arthritis: effects on synovial inflammation, bone erosion, and cartilage destruction

scientific article published on 01 January 2004

Sirukumab, a human anti-interleukin-6 monoclonal antibody: a randomised, 2-part (proof-of-concept and dose-finding), phase II study in patients with active rheumatoid arthritis despite methotrexate therapy

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Soluble RANKL and risk of nontraumatic fracture

scientific article published on March 2004

Sonographic joint assessment in rheumatoid arthritis: associations with clinical joint assessment during a state of remission

scientific article published in August 2013

Superior efficacy of combination therapy for rheumatoid arthritis: fact or fiction?

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Sustained benefits of infliximab therapy for dermatologic and articular manifestations of psoriatic arthritis: results from the infliximab multinational psoriatic arthritis controlled trial (IMPACT)

scientific article published on 01 April 2005

Sustained efficacy of certolizumab pegol added to methotrexate in the treatment of rheumatoid arthritis: 2-year results from the RAPID 1 trial

scientific article published on 16 May 2012

Synovial fibroblasts self-direct multicellular lining architecture and synthetic function in three-dimensional organ culture

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Systemic lupus erythematosus. Disease outcome in patients with a disease duration of at least 10 years: second evaluation

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Systemic lupus erythematosus: clinical features in patients with a disease duration of over 10 years, first evaluation

scientific article published on 01 October 1999

TNF-induced structural joint damage is mediated by IL-1.

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Ten years of infliximab: insights from clinical trials in rheumatoid arthritis

scientific article published on 17 October 2009

Tenosynovitis and osteoclast formation as the initial preclinical changes in a murine model of inflammatory arthritis

scientific article published on 01 January 2007

The 2010 American College of Rheumatology/European League Against Rheumatism classification criteria for rheumatoid arthritis: Phase 2 methodological report

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The Simplified Disease Activity Index (SDAI) and Clinical Disease Activity Index (CDAI) to monitor patients in standard clinical care.

scientific article published in August 2007

The Simplified Disease Activity Index and Clinical Disease Activity Index to monitor patients in standard clinical care

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The Stop Arthritis Very Early (SAVE) trial, an international multicentre, randomised, double-blind, placebo-controlled trial on glucocorticoids in very early arthritis

scientific article published in March 2010

The active metabolite of leflunomide, A77 1726, interferes with dendritic cell function

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The appropriate use of non-steroidal anti-inflammatory drugs in rheumatic disease: opinions of a multidisciplinary European expert panel.

scientific article published on 10 September 2010

The assessment of disease activity in rheumatoid arthritis.

scientific article published on May 2010

The changing landscape of biosimilars in rheumatology

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The definition and measurement of disease modification in inflammatory rheumatic diseases

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The effects of structural damage on functional disability in psoriatic arthritis

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The efficacy of leflunomide monotherapy in rheumatoid arthritis: towards the goals of disease modifying antirheumatic drug therapy.

scientific article published on June 2004

The eumusc.net standards of care for rheumatoid arthritis: importance and current implementation according to patients and healthcare providers in the Netherlands

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The health assessment questionnaire in routine clinical practice

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The impact of infliximab treatment on quality of life in patients with inflammatory rheumatic diseases

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The impact of multimorbidity status on treatment response in rheumatoid arthritis patients initiating disease-modifying anti-rheumatic drugs

scientific article published on 10 July 2015

The importance of reporting disease activity states in rheumatoid arthritis clinical trials

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The need for prognosticators in rheumatoid arthritis. Biological and clinical markers: where are we now?

scientific article published on 29 May 2008

The pathogenesis of rheumatoid arthritis: new insights from old clinical data?

scientific article published on 13 March 2012

The patient perspective on remission in rheumatoid arthritis: ‘You've got limits, but you're back to being you again’

scientific article published on 12 February 2014

The public neglect of rheumatic diseases: insights from analyses of attendees in a musculoskeletal disease awareness activity

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The relationship between joint damage and functional disability in rheumatoid arthritis: a systematic review

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The rheumatoid arthritis-associated autoantigen hnRNP-A2 (RA33) is a major stimulator of autoimmunity in rats with pristane-induced arthritis

scientific article published in December 2007

The role of biosimilars in the treatment of rheumatic diseases

scientific article published on 19 December 2012

The role of osteoprotegerin in arthritis

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The role of tumor necrosis factor-alpha in systemic lupus erythematosus

scientific article published on 23 January 2008

The science of rheumatoid arthritis: a prelude.

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The spliceosomal autoantigen heterogeneous nuclear ribonucleoprotein A2 (hnRNP-A2) is a major T cell autoantigen in patients with systemic lupus erythematosus

scientific article published on January 2006

The unmet need in rheumatology: Reports from the targeted therapies meeting 2017.

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The unmet need in rheumatology: reports from the Targeted Therapies meeting 2016

scientific article (publication date: 2016)

The when and how of biologic agent withdrawal in rheumatoid arthritis: learning from large randomised controlled trials

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Therapeutic blockade of TNF in patients with SLE-promising or crazy?

scientific article published on 18 May 2011

Therapeutic strategies for rheumatoid arthritis

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Therapeutic strategies in early rheumatoid arthritis

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Therapy of systemic lupus erythematosus: a look into the future

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Threats to validity of observational studies on disease-modifying antirheumatic drug therapies for rheumatoid arthritis: new aspects after the fall of the pyramid and the rise of new therapeutics

scientific article published in December 2003

Tocilizumab inhibits progression of joint damage in rheumatoid arthritis irrespective of its anti-inflammatory effects: disassociation of the link between inflammation and destruction

scientific article published on 25 November 2011

Tocilizumab.

scientific article published in April 2009

Toreforant, A Histamine H4 Receptor Antagonist, in Patients with Active Rheumatoid Arthritis Despite Methotrexate Therapy: Results of 2 Phase II Studies

scientific article published on 15 July 2016

Towards consensus in defining and handling contextual factors within rheumatology trials: an initial qualitative study from an OMERACT working group

scientific article published on 14 October 2020

Treat-to-target as an approach in inflammatory arthritis

scientific article published on May 2016

Treat-to-target in systemic lupus erythematosus: recommendations from an international task force.

scientific article published on 16 April 2014

Treat-to-target: rationale and strategies.

scientific article published on July 2012

Treating Rheumatoid Arthritis to Target: multinational recommendations assessment questionnaire

scientific article published on 29 July 2011

Treating axial spondyloarthritis and peripheral spondyloarthritis, especially psoriatic arthritis, to target: 2017 update of recommendations by an international task force ⬇️

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Treating rheumatoid arthritis to target: 2014 update of the recommendations of an international task force ⬇️

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Treating rheumatoid arthritis to target: recommendations of an international task force

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Treating spondyloarthritis, including ankylosing spondylitis and psoriatic arthritis, to target: recommendations of an international task force

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Treatment Patterns of Multimorbid Patients with Rheumatoid Arthritis: Results from an International Cross-sectional Study

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Treatment of psoriatic arthritis: management recommendations

scientific article published on 15 October 2015

Treatment of rheumatoid arthritis by TNF-blocking agents

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Tumor necrosis factor alpha-mediated joint destruction is inhibited by targeting osteoclasts with osteoprotegerin

scientific article published in March 2002

Tumor necrosis factor-inhibiting therapy preferentially targets bone destruction but not synovial inflammation in a tumor necrosis factor-driven model of rheumatoid arthritis.

scientific article

Tumour necrosis factor activates the mitogen-activated protein kinases p38alpha and ERK in the synovial membrane in vivo

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Two-year efficacy and safety of infliximab treatment in patients with active psoriatic arthritis: findings of the Infliximab Multinational Psoriatic Arthritis Controlled Trial (IMPACT).

scientific article published on 15 March 2008

Unmet need in rheumatology: reports from the Targeted Therapies meeting 2019

scientific article published on 29 October 2019

Updated consensus statement on biological agents for the treatment of rheumatic diseases, 2012.

scientific article published on April 2013

Use of Consensus Methodology to Determine Candidate Items for Systemic Lupus Erythematosus Classification Criteria

scientific article published on 15 December 2018

Use of combination of leflunomide with biological agents in treatment of rheumatoid arthritis

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Value of self-performed joint counts in rheumatoid arthritis patients near remission

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Vitamin D receptor regulates TNF-mediated arthritis

scientific article published on 17 March 2011

What is the place of recently approved T cell-targeted and B cell-targeted therapies in the treatment of rheumatoid arthritis? Lessons from global clinical trials.

scientific article published on July 2007

When rheumatologists report that they agree with a guideline, does this mean that they practise the guideline in clinical practice? Results of the International Recommendation Implementation Study (IRIS).

scientific article published on 28 April 2016

Zoledronic acid protects against local and systemic bone loss in tumor necrosis factor-mediated arthritis

scientific article published in July 2004

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