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List of works by Mary L. Bouxsein

25-Hydroxyvitamin-D and Bone Turnover Marker Levels in Patients with Distal Radial Fracture

scientific article published in October 2015

A FAK/HDAC5 signaling axis controls osteocyte mechanotransduction

scientific article published on 01 July 2020

A Proteasome Inhibitor, Bortezomib, Inhibits Breast Cancer Growth and Reduces Osteolysis by Downregulating Metastatic Genes ⬇️

scientific article published on September 15, 2010

A biomechanical model for estimating loads on thoracic and lumbar vertebrae

scientific article

A bone structural basis for fracture risk in diabetes

scientific article published on 16 September 2008

A novel partial gravity ground-based analogue for rats via quadrupedal unloading

scientific article published on 22 March 2018

A prospective field study of U.S. Army trainees to identify the physiological bases and key factors influencing musculoskeletal injuries: a study protocol.

scientific article published on 12 June 2019

A review of rodent models of type 2 diabetic skeletal fragility

scientific article published on January 2014

A single percutaneous injection of recombinant human bone morphogenetic protein-2 accelerates fracture repair

scientific article published in August 2003

A soluble activin receptor Type IIA fusion protein (ACE-011) increases bone mass via a dual anabolic-antiresorptive effect in Cynomolgus monkeys

scientific article published on 18 January 2010

A soluble activin type IIA receptor induces bone formation and improves skeletal integrity

scholarly article

A soluble bone morphogenetic protein type IA receptor increases bone mass and bone strength ⬇️

scientific article published on July 3, 2012

Adolescent Girls With Anorexia Nervosa Have Impaired Cortical and Trabecular Microarchitecture and Lower Estimated Bone Strength at the Distal Radius ⬇️

scientific article published on March 18, 2013

Age- and sex-specific differences in the factor of risk for vertebral fracture: a population-based study using QCT.

scientific article published in September 2006

Age-related changes in trabecular architecture differ in female and male C57BL/6J mice

scientific article published in August 2007

Altered thermogenesis and impaired bone remodeling in Misty mice ⬇️

scientific article published on September 1, 2013

An essential role for the circadian‐regulated gene Nocturnin in osteogenesis: the importance of local timekeeping in skeletal homeostasis ⬇️

scientific article published on November 1, 2011

Association Between Insulin Resistance and Bone Structure in Nondiabetic Postmenopausal Women

scientific article

BMP type I receptor inhibition reduces heterotopic [corrected] ossification

scientific article

Beta-arrestin-biased parathyroid hormone ligands: a new approach to the development of agents that stimulate bone formation

scientific article

Biomechanics of vertebral fractures and the vertebral fracture cascade

scientific article published on December 2010

Bisphosphonate Withdrawal: Effects on Bone Formation and Bone Resorption in Maturing Male Mice

scientific article published on 7 December 2016

Bone Density and Trabecular Morphology at Least 10 Years After Gastric Bypass and Gastric Banding

scientific article published on 15 June 2020

Bone Loss After Bariatric Surgery: Discordant Results Between DXA and QCT Bone Density ⬇️

scientific article published on March 1, 2014

Bone Microarchitecture Is Impaired in Adolescent Amenorrheic Athletes Compared with Eumenorrheic Athletes and Nonathletic Controls ⬇️

scientific article published on August 3, 2011

Bone Strength Estimated by Micro-Finite Element Analysis (µFEA) Is Heritable and Shares Genetic Predisposition With Areal BMD: The Framingham Study

scientific article published on 19 July 2017

Bone consolidation is enhanced by rhBMP-2 in a rabbit model of distraction osteogenesis

scientific article

Bone density and strength from thoracic and lumbar CT scans both predict incident vertebral fractures independently of fracture location

scientific article published on 03 August 2020

Bone geometry and skeletal fragility

scientific article published on June 2006

Bone health in subjects with type 1 diabetes for more than 50 years

scientific article

Bone mass, microarchitecture and strength are influenced by race/ethnicity in young adult men and women

scientific article published on 13 July 2017

Bone outcomes following sleeve gastrectomy in adolescents and young adults with obesity versus non-surgical controls

scientific article published on 19 February 2020

Bone quality: where do we go from here? ⬇️

scientific article published on August 29, 2003

Change in Bone Density and Reduction in Fracture Risk: A Meta-Regression of Published Trials

scientific article published on 23 January 2019

Changes in tibial bone microarchitecture in female recruits in response to 8 weeks of U.S. Army Basic Combat Training

scientific article published on 27 April 2018

Clinical use of quantitative computed tomography and peripheral quantitative computed tomography in the management of osteoporosis in adults: the 2007 ISCD Official Positions

scientific article

Combined effects of botulinum toxin injection and hind limb unloading on bone and muscle

scientific article

Combined treatment with a beta-blocker and intermittent PTH improves bone mass and microarchitecture in ovariectomized mice

scientific article published on 10 March 2006

Comparative effects of teriparatide, denosumab, and combination therapy on peripheral compartmental bone density, microarchitecture, and estimated strength: the DATA-HRpQCT Study

scientific article

Comparison of cyclic and impact-based reference point indentation measurements in human cadaveric tibia

scientific article published on 7 April 2015

Comparison of non-invasive assessments of strength of the proximal femur

scientific article

Comparison of radiographic fracture healing in the distal radius for patients on and off bisphosphonate therapy

scientific article

Comparison of skeletal effects of ovariectomy versus chemically induced ovarian failure in mice

scientific article published on August 2008

Compromised bone microarchitecture and estimated bone strength in young adults with cystic fibrosis

scientific article

Computed tomography-based muscle attenuation and electrical impedance myography as indicators of trunk muscle strength independent of muscle size in older adults

scientific article

Congenic mice with low serum IGF-I have increased body fat, reduced bone mineral density, and an altered osteoblast differentiation program

scientific article

Congenic strains of mice for verification and genetic decomposition of quantitative trait loci for femoral bone mineral density

scientific article published in February 2003

Considerations for development of surrogate endpoints for antifracture efficacy of new treatments in osteoporosis: a perspective

scientific article published on August 2008

Contribution of In Vivo Structural Measurements and Load/Strength Ratios to the Determination of Forearm Fracture Risk in Postmenopausal Women

article by L Joseph Melton et al published 29 May 2007 in Journal of Bone and Mineral Research

Control of bone mass and remodeling by PTH receptor signaling in osteocytes

scientific article

Control of osteocyte dendrite formation by Sp7 and its target gene osteocrin

scientific article published on 01 November 2021

Correction: Spaceflight Activates Lipotoxic Pathways in Mouse Liver

scientific article published on 4 May 2016

Corrigendum: SIKs control osteocyte responses to parathyroid hormone

scientific article published on 22 February 2017

Cortical and trabecular deterioration in mouse models of Roux-en-Y gastric bypass

scientific article published on 21 January 2016

Cortical and trabecular load sharing in the human femoral neck.

scientific article published on 24 December 2014

Cortical bone material strength index and bone microarchitecture in postmenopausal women with atypical femoral fractures

scientific article published on 05 November 2018

Cortical microstructure and estimated bone strength in young amenorrheic athletes, eumenorrheic athletes and non-athletes ⬇️

scientific article published on August 2, 2012

Decreased BMD and limb deformities in mice carrying mutations in both Lrp5 and Lrp6

scientific journal article

Determinants of Bone Microarchitecture and Mechanical Properties in Obese Men ⬇️

scientific article published on August 29, 2012

Determinants of skeletal fragility

scientific article

Determinants of the mechanical behavior of human lumbar vertebrae after simulated mild fracture

scientific article

Development and Validation of a Musculoskeletal Model of the Fully Articulated Thoracolumbar Spine and Rib Cage

scientific article published on 09 June 2015

Diabetes and Deficits in Cortical Bone Density, Microarchitecture, and Bone Size: Framingham HR-pQCT Study.

scientific article published on 20 September 2017

Differences in Trabecular Microstructure Between Black and White Women Assessed by Individual Trabecular Segmentation Analysis of HR-pQCT Images

scientific article published on 13 December 2016

Differences in skeletal microarchitecture and strength in African-American and white women ⬇️

scientific article published on October 1, 2013

Distinguishing neuromuscular disorders based on the passive electrical material properties of muscle

scientific article

Effect of bisphosphonates on the rapidly growing male murine skeleton

scientific article published on 14 January 2014

Effect of follower load on motion and stiffness of the human thoracic spine with intact rib cage

scientific article published on 8 August 2016

Effect of type 2 diabetes-related non-enzymatic glycation on bone biomechanical properties

scientific article

Effects of Combination Denosumab and High-Dose Teriparatide Administration on Bone Microarchitecture and Estimated Strength: the DATA-HD HR-pQCT Study

scientific article published on 13 August 2020

Effects of Denosumab and Teriparatide Transitions on Bone Microarchitecture and Estimated Strength: the DATA-Switch HR-pQCT study

scientific article

Effects of Estrogen Replacement on Bone Geometry and Microarchitecture in Adolescent and Young Adult Oligoamenorrheic Athletes: A Randomized Trial

scientific article published on 07 November 2019

Effects of Long-Duration Spaceflight on Vertebral Strength and Risk of Spine Fracture

scientific article published on 31 October 2019

Effects of OP-1 and PTH in a new experimental model for the study of metaphyseal bone healing

scientific article published in September 2007

Effects of follower load and rib cage on intervertebral disc pressure and sagittal plane curvature in static tests of cadaveric thoracic spines

scientific article published on 26 February 2016

Effects of preexisting microdamage, collagen cross-links, degree of mineralization, age, and architecture on compressive mechanical properties of elderly human vertebral trabecular bone

scientific article

Essential role of beta-catenin in postnatal bone acquisition

scientific journal article

Estimating apparent maximum muscle stress of trunk extensor muscles in older adults using subject-specific musculoskeletal models

scientific article published on 9 June 2017

Evaluation of a new approach to compute intervertebral disc height measurements from lateral radiographic views of the spine

scientific article published on 18 October 2016

Extracellular post-translational modifications of collagen are major determinants of biomechanical properties of fetal bovine cortical bone

scientific article published on 3 November 2005

Familial aggregation of bone mineral density and bone mineral content in a Chinese population

scientific article

Fracture Prediction by Computed Tomography and Finite Element Analysis: Current and Future Perspectives

scientific article published on 01 August 2018

Growth hormone protects against ovariectomy-induced bone loss in states of low circulating insulin-like growth factor (IGF-1).

scientific article

Guidelines for assessment of bone microstructure in rodents using micro-computed tomography

scientific article published on July 2010

Guidelines for the assessment of bone density and microarchitecture in vivo using high-resolution peripheral quantitative computed tomography

scientific article published on 26 May 2020

HDAC5 controls MEF2C-driven sclerostin expression in osteocytes

scientific article

Harmonizing finite element modelling for non-invasive strength estimation by high-resolution peripheral quantitative computed tomography

scholarly article by Danielle E Whittier et al published 26 October 2018 in Journal of Biomechanics

Heritability and Genetic Correlations for Bone Microarchitecture: The Framingham Study Families

scientific article published on 15 July 2016

Heritability of Thoracic Spine Curvature and Genetic Correlations With Other Spine Traits: The Framingham Study

scientific article published on 25 July 2016

High bone mass in mice expressing a mutant LRP5 gene

scientific article (publication date: June 2003)

High dose of Zoledronic acid inhibits both osteoclasts and osteoblasts in an In Vivo mouse model

High-dose zoledronic acid impacts bone remodeling with effects on osteoblastic lineage and bone mechanical properties

scientific article

Hypoxia-inducible factors 1alpha and 2alpha exert both distinct and overlapping functions in long bone development

scientific article published in January 2010

Impact of seafood and fruit consumption on bone mineral density

scientific article published on 27 June 2006

Improving evaluation and treatment for osteoporosis following distal radial fractures. A prospective randomized intervention

scientific article published on May 2008

In vivo assessment of trabecular bone microarchitecture by high-resolution peripheral quantitative computed tomography

scientific article published on 27 September 2005

In vivo targeted deletion of calpain small subunit, Capn4, in cells of the osteoblast lineage impairs cell proliferation, differentiation, and bone formation

scientific article published on 30 May 2008

Incorporating Six Degree-of-Freedom Intervertebral Joint Stiffness in a Lumbar Spine Musculoskeletal Model-Method and Performance in Flexed Postures

scientific article published on 24 August 2015

Inducible podocyte-specific deletion of CTCF drives progressive kidney disease and bone abnormalities

scientific article published on 22 February 2018

Influence of early and late zoledronic acid administration on vertebral structure and strength in ovariectomized rats

scientific article published on 19 August 2008

Infrequent delivery of a long-acting PTH-Fc fusion protein has potent anabolic effects on cortical and cancellous bone

scientific article

Inhibiting activin-A signaling stimulates bone formation and prevents cancer-induced bone destruction in vivo

scientific article

Inhibition of growth hormone action improves insulin sensitivity in liver IGF-1-deficient mice

scientific article

Inhibition of osteoclast differentiation and collagen antibody-induced arthritis by CTHRC1.

scientific article published on 20 January 2017

Insights from the conduct of a device trial in older persons: low magnitude mechanical stimulation for musculoskeletal health

scientific article

Insights into foraminiferal influences on microfabrics of microbialites at Highborne Cay, Bahamas

scientific article

Irisin levels are lower in young amenorrheic athletes compared with eumenorrheic athletes and non-athletes and are associated with bone density and strength estimates

scientific article

Large-scale genome-wide linkage analysis for loci linked to BMD at different skeletal sites in extreme selected sibships

scientific article

Low-Magnitude Mechanical Stimulation to Improve Bone Density in Persons of Advanced Age: A Randomized, Placebo-Controlled Trial

scientific article

Lumbar Vertebral Body Bone Microstructural Scaling in Small to Medium‐Sized Strepsirhines ⬇️

scientific article published on February 1, 2013

Mechanical properties of the scapholunate ligament correlate with bone mineral density measurements of the hand

scientific article published in July 2004

Mechanisms of disease: is osteoporosis the obesity of bone?

scientific article published on January 2006

Mechanisms of osteoporosis therapy: a bone strength perspective

scientific article published on January 2003

Megakaryocyte-osteoblast interaction revealed in mice deficient in transcription factors GATA-1 and NF-E2

scientific journal article

Metastatic osteosarcoma induced by inactivation of Rb and p53 in the osteoblast lineage

scholarly article

Microarchitecture influences microdamage accumulation in human vertebral trabecular bone

scientific article published on October 2008

Microstructural failure mechanisms in the human proximal femur for sideways fall loading

scientific article published in February 2014

Multicenter precision of cortical and trabecular bone quality measures assessed by high-resolution peripheral quantitative computed tomography

scientific article published on March 2013

Nocturnal oxytocin secretion is lower in amenorrheic athletes than nonathletes and associated with bone microarchitecture and finite element analysis parameters

scientific article published on 20 February 2013

Nonsteroidal Anti-Inflammatory Drug Prescriptions are Associated with Increased Stress Fracture Diagnosis in the U.S. Army Population

scientific article published on 10 December 2018

Novel Genetic Variants Associated With Increased Vertebral Volumetric BMD, Reduced Vertebral Fracture Risk, and Increased Expression of SLC1A3 and EPHB2.

scientific article published in August 2016

Osteoblast-restricted Disruption of the Growth Hormone Receptor in Mice Results in Sexually Dimorphic Skeletal Phenotypes

scientific article published on 29 March 2013

Osteoporosis and Hip Fracture Risk From Routine Computed Tomography Scans: The Fracture, Osteoporosis, and CT Utilization Study (FOCUS).

scientific article published on 17 April 2018

Osteoporosis update from the 2012 Santa Fe Bone Symposium

scientific article published on 15 February 2013

PPARG by dietary fat interaction influences bone mass in mice and humans

scientific article published on September 2008

Parental diabetes: the Akita mouse as a model of the effects of maternal and paternal hyperglycemia in wildtype offspring

scientific article (publication date: 2012)

Partial weight suspension: a novel murine model for investigating adaptation to reduced musculoskeletal loading

scientific article published on 03 June 2010

Patterns of load-to-strength ratios along the spine in a population-based cohort to evaluate the contribution of spinal loading to vertebral fractures

scientific article published on 30 November 2020

Phospholipase C signaling via the parathyroid hormone (PTH)/PTH-related peptide receptor is essential for normal bone responses to PTH.

scientific article

Population-based analysis of the relationship of whole bone strength indices and fall-related loads to age- and sex-specific patterns of hip and wrist fractures

scientific article

Population-based study of age and sex differences in bone volumetric density, size, geometry, and structure at different skeletal sites

scientific article

Predicting the failure load of the distal radius ⬇️

scientific article published on April 25, 2003

Premenopausal women with a distal radial fracture have deteriorated trabecular bone density and morphology compared with controls without a fracture

scientific article published on April 2013

Progenitor recruitment and adipogenic lipolysis contribute to the anabolic actions of parathyroid hormone on the skeleton

article

Prolonged signaling at the parathyroid hormone receptor by peptide ligands targeted to a specific receptor conformation

scholarly article

Proximal femoral structure and the prediction of hip fracture in men: a large prospective study using QCT.

scientific article published on August 2008

QCT measures of bone strength at the thoracic and lumbar spine: the Framingham Study

scientific article published on March 2012

Quantifying the material and structural determinants of bone strength

scientific article published on December 2009

Rac signaling in osteoblastic cells is required for normal bone development but is dispensable for hematopoietic development

scientific article published on 28 November 2011

Racial Differences in Bone Microarchitecture and Estimated Strength at the Distal Radius and Distal Tibia in Older Adolescent Girls: a Cross-Sectional Study.

scientific article published on 7 July 2016

Randomized trial of once-weekly parathyroid hormone (1-84) on bone mineral density and remodeling

scientific article published on 18 March 2008

Recombinant human bone morphogenetic protein-2 delivered in an injectable calcium phosphate paste accelerates osteotomy-site healing in a nonhuman primate model.

scientific article published in September 2004

Recommendations for optimal care of the fragility fracture patient to reduce the risk of future fracture

scientific article

Red and White Blood Cell Counts Are Associated With Bone Marrow Adipose Tissue, Bone Mineral Density, and Bone Microarchitecture in Premenopausal Women

scientific article published on 20 February 2020

Regressions for estimating muscle parameters in the thoracic and lumbar trunk for use in musculoskeletal modeling

scientific article published on 22 October 2011

Regulation of lean mass, bone mass, and exercise tolerance by the central melanocortin system

scientific article

Relation of body composition, fat mass, and serum lipids to osteoporotic fractures and bone mineral density in Chinese men and women

scientific article published in January 2006

Reply to: Change in Bone Density and Reduction in Fracture Risk: A Meta-Regression of Published Trials

scientific article published on 21 August 2019

Response letter to the editor

scientific article

Response to: Some Questions About the Article "The Efficacy and Safety of Vertebral Augmentation: A Second ASBMR Task Force Report"

scientific article published on 19 November 2019

Retaining Residual Ovarian Tissue following Ovarian Failure Has Limited Influence on Bone Loss in Aged Mice

scientific article

Risedronate reduces intracortical porosity in women with osteoporosis.

scientific article

Risk of Stress Fracture Varies by Race/Ethnic Origin in a Cohort Study of 1.3 Million US Army Soldiers

scientific article

Role of trabecular microarchitecture and its heterogeneity parameters in the mechanical behavior of ex vivo human L3 vertebrae

scientific article

SIKs control osteocyte responses to parathyroid hormone

scientific article published on 19 October 2016

Sclerostin antibody inhibits skeletal deterioration due to reduced mechanical loading ⬇️

scientific article published on April 1, 2013

Serum FGF-21 levels are associated with worsened radial trabecular bone microarchitecture and decreased radial bone strength in women with anorexia nervosa

scientific article published on 11 April 2015

Serum IGF-1 determines skeletal strength by regulating subperiosteal expansion and trait interactions

scientific article published on August 2009

Serum complexes of insulin-like growth factor-1 modulate skeletal integrity and carbohydrate metabolism

scientific article published on 24 October 2008

Spaceflight environment induces mitochondrial oxidative damage in ocular tissue

scientific article

Specimen size and porosity can introduce error into microCT-based tissue mineral density measurements

scientific article

Spinal Loading Patterns From Biomechanical Modeling Explain the High Incidence of Vertebral Fractures in the Thoracolumbar Region

scientific article

Spontaneous mutation of Dock7 results in lower trabecular bone mass and impaired periosteal expansion in aged female Misty mice

scientific article

Stk11 (Lkb1) deletion in the osteoblast lineage leads to high bone turnover, increased trabecular bone density and cortical porosity

scientific article

Structural and functional properties of bone are compromised in amyotrophic lateral sclerosis mice

scientific article published on 23 March 2018

Suppression of Wnt signaling by Dkk1 attenuates PTH-mediated stromal cell response and new bone formation

scientific article

Systems genetics in diversity outbred mice inform BMD GWAS and identify determinants of bone strength

scientific article published on 07 June 2021

Technology insight: noninvasive assessment of bone strength in osteoporosis

scientific article published on 22 April 2008

Teriparatide and raloxifene reduce the risk of new adjacent vertebral fractures in postmenopausal women with osteoporosis. Results from two randomized controlled trials

scientific article published in June 2009

Teriparatide increases bone formation and bone mineral density in adult women with anorexia nervosa

scientific article published on 23 January 2014

The Efficacy and Safety of Vertebral Augmentation: A Second ASBMR Task Force Report

scientific article published on 01 January 2019

The effect of thoracic kyphosis and sagittal plane alignment on vertebral compressive loading ⬇️

scientific article published on October 1, 2012

The effects of GATA-1 and NF-E2 deficiency on bone biomechanical, biochemical, and mineral properties

scientific article

The effects of parathyroid hormone and alendronate alone or in combination in postmenopausal osteoporosis

scientific article published on 20 September 2003

The heparin-binding domain of IGFBP-2 has insulin-like growth factor binding-independent biologic activity in the growing skeleton

scientific article

The heparin-binding domain of IGFBP-2 has insulin-like growth factor binding-independent biologic activity in the growing skeleton.

scientific article published in December 2011

The rib cage reduces intervertebral disc pressures in cadaveric thoracic spines by sharing loading under applied dynamic moments

scientific article published on 12 October 2017

The role of adaptive bone formation in the etiology of stress fracture

scientific article

Theoretical effects of fully ductile versus fully brittle behaviors of bone tissue on the strength of the human proximal femur and vertebral body

scientific article published on 12 March 2015

Theoretical implications of the biomechanical fracture threshold

scientific article published on October 2008

Thoracic Kyphosis and Physical Function: The Framingham Study

scientific article

Treatment With a Soluble Bone Morphogenetic Protein Type 1A Receptor (BMPR1A) Fusion Protein Increases Bone Mass and Bone Formation in Mice Subjected to Hindlimb Unloading

Treatment with a soluble receptor for activin improves bone mass and structure in the axial and appendicular skeleton of female cynomolgus macaques (Macaca fascicularis).

scientific article published on 23 September 2009

Treatment-Related Changes in Bone Turnover and Fracture Risk Reduction in Clinical Trials of Anti-Resorptive Drugs: A Meta-Regression

scientific article published on 10 January 2018

Treatment-related changes in bone mineral density as a surrogate biomarker for fracture risk reduction: meta-regression analyses of individual patient data from multiple randomised controlled trials

scientific article published on 01 August 2020

Trochanteric soft tissue thickness and hip fracture in older men

scientific article

Two-year changes in bone density after Roux-en-Y gastric bypass surgery

scientific article

Vertebral Strength and Estimated Fracture Risk Across the BMI Spectrum in Women

scientific article published on 31 August 2015

Vertebral Volumetric Bone Density and Strength Are Impaired in Women With Low-Weight and Atypical Anorexia Nervosa

scientific article published on 12 October 2016

Vertebral fracture assessment using standard bone densitometry equipment predicts incident fractures in women

scientific article published on 7 October 2008

Vertebral size, bone density, and strength in men and women matched for age and areal spine BMD

scientific article

beta-Arrestin2 regulates the differential response of cortical and trabecular bone to intermittent PTH in female mice

scientific article

miR-30-5p functions as a tumor suppressor and novel therapeutic tool by targeting the oncogenic Wnt/β-catenin/BCL9 pathway

scientific article

rhBMP-2 induces transient bone resorption followed by bone formation in a nonhuman primate core-defect model

scientific article published in February 2010

rhBMP-2/calcium phosphate matrix accelerates osteotomy-site healing in a nonhuman primate model at multiple treatment times and concentrations

scientific article published in January 2006

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