List of works - Jens Wrammert

3M-052, a synthetic TLR-7/8 agonist, induces durable HIV-1 envelope-specific plasma cells and humoral immunity in nonhuman primates

scientific article published on 01 June 2020

A three-dose intramuscular injection schedule of anthrax vaccine adsorbed generates sustained humoral and cellular immune responses to protective antigen and provides long-term protection against inhalation anthrax in rhesus macaques

scientific article

Adjuvanting a Simian Immunodeficiency Virus Vaccine with Toll-Like Receptor Ligands Encapsulated in Nanoparticles Induces Persistent Antibody Responses and Enhanced Protection in TRIM5α Restrictive Macaques

scientific article

Affinity selection and repertoire shift: paradoxes as a consequence of somatic mutation? ⬇️

scientific article published on April 1, 1998

An Amphibian Host Defense Peptide Is Virucidal for Human H1 Hemagglutinin-Bearing Influenza Viruses ⬇️

scientific article

Antibody pressure by a human monoclonal antibody targeting the 2009 pandemic H1N1 virus hemagglutinin drives the emergence of a virus with increased virulence in mice

scientific article

Antibody-Secreting Cell Responses after Vibrio cholerae O1 Infection and Oral Cholera Vaccination in Adults in Bangladesh ⬇️

scientific article published on August 14, 2013

Antigen-specific memory B-cell responses to Vibrio cholerae O1 infection in Bangladesh

scientific article published on 15 June 2009

Antigenic Drift of the Influenza A(H1N1)pdm09 Virus Neuraminidase Results in Reduced Effectiveness of A/California/7/2009 (H1N1pdm09)-Specific Antibodies

scientific article published in 2019

B Cell Responses during Secondary Dengue Virus Infection Are Dominated by Highly Cross-Reactive, Memory-Derived Plasmablasts

scientific article published on 30 March 2016

B cell responses to influenza infection and vaccination

scientific article published on January 2015

BALDR: a computational pipeline for paired heavy and light chain immunoglobulin reconstruction in single-cell RNA-seq data

scientific article published on 20 March 2018

Broadly Reactive Human Monoclonal Antibodies Elicited following Pandemic H1N1 Influenza Virus Exposure Protect Mice against Highly Pathogenic H5N1 Challenge

scholarly article by Raffael Nachbagauer published in August 2018

Broadly cross-reactive antibodies dominate the human B cell response against 2009 pandemic H1N1 influenza virus infection

scientific article

Broadly cross-reactive antibodies dominate the human B cell response against 2009 pandemic H1N1 influenza virus infection

scientific article published on 7 February 2011

Complement-dependent lysis of influenza a virus-infected cells by broadly cross-reactive human monoclonal antibodies

scientific article published on 12 October 2011

Corrigendum: Rapid generation of fully human monoclonal antibodies specific to a vaccinating antigen

scientific article published on November 2014

Cross-Reactive Dengue Virus Antibodies Augment Zika Virus Infection of Human Placental Macrophages

scholarly article published by Carolyn Coyne in 2018

Cross-reactive humoral responses to influenza and their implications for a universal vaccine

scientific article

Dengue virus infection induces expansion of a CD14(+)CD16(+) monocyte population that stimulates plasmablast differentiation

scientific article

Evaluation of multiplex assay platforms for detection of influenza hemagglutinin subtype specific antibody responses

scientific article published on 17 January 2017

Frequency and phenotype of human immunodeficiency virus envelope-specific B cells from patients with broadly cross-neutralizing antibodies

scientific article published on 15 October 2008

Hemagglutinin stalk antibodies elicited by the 2009 pandemic influenza virus as a mechanism for the extinction of seasonal H1N1 viruses

scientific article

High Affinity Antibodies against Influenza Characterize the Plasmablast Response in SLE Patients After Vaccination

scientific article published on 7 May 2015

Human antibody responses after dengue virus infection are highly cross-reactive to Zika virus

scientific article

Human immune memory to yellow fever and smallpox vaccination

scientific article published on 4 December 2008

Humoral Immune Responses Against Zika Virus Infection and the Importance of Preexisting Flavivirus Immunity

scientific article published in December 2017

Humoral and Cell-Mediated Immune Responses to Alternate Booster Schedules of Anthrax Vaccine Adsorbed in Humans

scientific article

Humoral cross-reactivity between Zika and dengue viruses: implications for protection and pathology

scientific article (publication date: 10 May 2017)

Identification of a novel thioredoxin-related protein, PC-TRP, which is preferentially expressed in plasma cells

scientific article published on January 2004

IgG antibodies to dengue enhanced for FcγRIIIA binding determine disease severity

scientific article

Immune history profoundly affects broadly protective B cell responses to influenza.

scientific article

Immune history shapes specificity of pandemic H1N1 influenza antibody responses.

scientific article

Impaired Antibody-mediated Protection and Defective IgA B-Cell Memory in Experimental Infection of Adults with Respiratory Syncytial Virus

scientific article published on May 2015

Implications of broadly neutralizing antibodies in the development of a universal influenza vaccine

scientific article

In vitro assessment of the immunological significance of a human monoclonal antibody directed to the influenza a virus nucleoprotein

scientific article published on 12 June 2013

Induction of broadly cross-reactive antibody responses to the influenza HA stem region following H5N1 vaccination in humans.

scientific article

Induction of human plasmablasts during infection with antibiotic-resistant nosocomial bacteria

scientific article

Influenza Infection in Humans Induces Broadly Cross-Reactive and Protective Neuraminidase-Reactive Antibodies

scientific article published in April 2018

Kinetics of antibody response to influenza vaccination in renal transplant recipients

scholarly article by Shivaprakash Gangappa et al published April 2019 in Transplant Immunology

Lack of peripheral memory B cell responses in recovered patients with severe acute respiratory syndrome: a six-year follow-up study

scientific article

Limited efficacy of inactivated influenza vaccine in elderly individuals is associated with decreased production of vaccine-specific antibodies

scientific article

Ly6C expression differentiates plasma cells from other B cell subsets in mice

article

Maintenance of serological memory

scientific article published on May 2008

Most influenza a virions fail to express at least one essential viral protein

scientific article published on 2 January 2013

Novel multiplex assay platforms to detect influenza A hemagglutinin subtype-specific antibody responses for high-throughput and in-field applications

scientific article published on 16 February 2017

Pandemic H1N1 influenza vaccine induces a recall response in humans that favors broadly cross-reactive memory B cells

scientific article

Postnatal Zika virus infection is associated with persistent abnormalities in brain structure, function, and behavior in infant macaques

scientific article published in April 2018

Potent Plasmablast-Derived Antibodies Elicited by the National Institutes of Health Dengue Vaccine

scientific article published on 6 September 2017

Pre-Existing Dengue Immunity Drives a DENV-Biased Plasmablast Response in ZIKV-Infected Patient

article

Preexisting human antibodies neutralize recently emerged H7N9 influenza strains.

scientific article

Proteome-wide analysis of the serological response to vaccinia and smallpox

scientific article published on May 2007

Rapid and massive virus-specific plasmablast responses during acute dengue virus infection in humans

scientific article published on 11 January 2012

Rapid cloning of high-affinity human monoclonal antibodies against influenza virus

scientific article

Rapid generation of fully human monoclonal antibodies specific to a vaccinating antigen

scientific article

Rapid generation of neutralizing antibody responses in COVID-19 patients

scientific article published on 08 May 2020

Robust memory responses against influenza vaccination in pemphigus patients previously treated with rituximab

scientific article

Single-Cell Analysis of the Plasmablast Response to Vibrio cholerae Demonstrates Expansion of Cross-Reactive Memory B Cells

scientific article published on 20 December 2016

Strong differential regulation of serum and mucosal IgA responses as revealed in CD28-deficient mice using cholera toxin adjuvant

article

Strong, but Age-Dependent, Protection Elicited by a Deoxyribonucleic Acid/Modified Vaccinia Ankara Simian Immunodeficiency Virus Vaccine

scientific article published on January 2016

Systems analysis of protective immune responses to RTS,S malaria vaccination in humans

scientific article published on 13 February 2017

Systems biology of vaccination for seasonal influenza in humans

scientific article

Vaccine induction of antibodies and tissue-resident CD8+ T cells enhances protection against mucosal SHIV-infection in young macaques

Vaccine-induced plasmablast responses in rhesus macaques: phenotypic characterization and a source for generating antigen-specific monoclonal antibodies

scientific article

Zika Virus Infects Human Placental Macrophages

scientific article

List of works by Jens Wrammert

3M-052, a synthetic TLR-7/8 agonist, induces durable HIV-1 envelope-specific plasma cells and humoral immunity in nonhuman primates

A three-dose intramuscular injection schedule of anthrax vaccine adsorbed generates sustained humoral and cellular immune responses to protective antigen and provides long-term protection against inhalation anthrax in rhesus macaques

Adjuvanting a Simian Immunodeficiency Virus Vaccine with Toll-Like Receptor Ligands Encapsulated in Nanoparticles Induces Persistent Antibody Responses and Enhanced Protection in TRIM5α Restrictive Macaques

Affinity selection and repertoire shift: paradoxes as a consequence of somatic mutation? ⬇️

An Amphibian Host Defense Peptide Is Virucidal for Human H1 Hemagglutinin-Bearing Influenza Viruses ⬇️

Antibody pressure by a human monoclonal antibody targeting the 2009 pandemic H1N1 virus hemagglutinin drives the emergence of a virus with increased virulence in mice

Antibody-Secreting Cell Responses after Vibrio cholerae O1 Infection and Oral Cholera Vaccination in Adults in Bangladesh ⬇️

Antigen-specific memory B-cell responses to Vibrio cholerae O1 infection in Bangladesh

Antigenic Drift of the Influenza A(H1N1)pdm09 Virus Neuraminidase Results in Reduced Effectiveness of A/California/7/2009 (H1N1pdm09)-Specific Antibodies

B Cell Responses during Secondary Dengue Virus Infection Are Dominated by Highly Cross-Reactive, Memory-Derived Plasmablasts

B cell responses to influenza infection and vaccination

BALDR: a computational pipeline for paired heavy and light chain immunoglobulin reconstruction in single-cell RNA-seq data

Broadly Reactive Human Monoclonal Antibodies Elicited following Pandemic H1N1 Influenza Virus Exposure Protect Mice against Highly Pathogenic H5N1 Challenge

Broadly cross-reactive antibodies dominate the human B cell response against 2009 pandemic H1N1 influenza virus infection

Broadly cross-reactive antibodies dominate the human B cell response against 2009 pandemic H1N1 influenza virus infection

Complement-dependent lysis of influenza a virus-infected cells by broadly cross-reactive human monoclonal antibodies

Corrigendum: Rapid generation of fully human monoclonal antibodies specific to a vaccinating antigen

Cross-Reactive Dengue Virus Antibodies Augment Zika Virus Infection of Human Placental Macrophages

Cross-reactive humoral responses to influenza and their implications for a universal vaccine

Dengue virus infection induces expansion of a CD14(+)CD16(+) monocyte population that stimulates plasmablast differentiation

Evaluation of multiplex assay platforms for detection of influenza hemagglutinin subtype specific antibody responses

Frequency and phenotype of human immunodeficiency virus envelope-specific B cells from patients with broadly cross-neutralizing antibodies

Hemagglutinin stalk antibodies elicited by the 2009 pandemic influenza virus as a mechanism for the extinction of seasonal H1N1 viruses

High Affinity Antibodies against Influenza Characterize the Plasmablast Response in SLE Patients After Vaccination

Human antibody responses after dengue virus infection are highly cross-reactive to Zika virus

Human immune memory to yellow fever and smallpox vaccination

Humoral Immune Responses Against Zika Virus Infection and the Importance of Preexisting Flavivirus Immunity

Humoral and Cell-Mediated Immune Responses to Alternate Booster Schedules of Anthrax Vaccine Adsorbed in Humans

Humoral cross-reactivity between Zika and dengue viruses: implications for protection and pathology

Identification of a novel thioredoxin-related protein, PC-TRP, which is preferentially expressed in plasma cells

IgG antibodies to dengue enhanced for FcγRIIIA binding determine disease severity

Immune history profoundly affects broadly protective B cell responses to influenza.

Immune history shapes specificity of pandemic H1N1 influenza antibody responses.

Impaired Antibody-mediated Protection and Defective IgA B-Cell Memory in Experimental Infection of Adults with Respiratory Syncytial Virus

Implications of broadly neutralizing antibodies in the development of a universal influenza vaccine

In vitro assessment of the immunological significance of a human monoclonal antibody directed to the influenza a virus nucleoprotein

Induction of broadly cross-reactive antibody responses to the influenza HA stem region following H5N1 vaccination in humans.

Induction of human plasmablasts during infection with antibiotic-resistant nosocomial bacteria

Influenza Infection in Humans Induces Broadly Cross-Reactive and Protective Neuraminidase-Reactive Antibodies

Kinetics of antibody response to influenza vaccination in renal transplant recipients

Lack of peripheral memory B cell responses in recovered patients with severe acute respiratory syndrome: a six-year follow-up study

Limited efficacy of inactivated influenza vaccine in elderly individuals is associated with decreased production of vaccine-specific antibodies

Ly6C expression differentiates plasma cells from other B cell subsets in mice

Maintenance of serological memory

Most influenza a virions fail to express at least one essential viral protein

Novel multiplex assay platforms to detect influenza A hemagglutinin subtype-specific antibody responses for high-throughput and in-field applications

Pandemic H1N1 influenza vaccine induces a recall response in humans that favors broadly cross-reactive memory B cells

Postnatal Zika virus infection is associated with persistent abnormalities in brain structure, function, and behavior in infant macaques

Potent Plasmablast-Derived Antibodies Elicited by the National Institutes of Health Dengue Vaccine

Pre-Existing Dengue Immunity Drives a DENV-Biased Plasmablast Response in ZIKV-Infected Patient

Preexisting human antibodies neutralize recently emerged H7N9 influenza strains.

Proteome-wide analysis of the serological response to vaccinia and smallpox

Rapid and massive virus-specific plasmablast responses during acute dengue virus infection in humans

Rapid cloning of high-affinity human monoclonal antibodies against influenza virus

Rapid generation of fully human monoclonal antibodies specific to a vaccinating antigen

Rapid generation of neutralizing antibody responses in COVID-19 patients

Robust memory responses against influenza vaccination in pemphigus patients previously treated with rituximab

Single-Cell Analysis of the Plasmablast Response to Vibrio cholerae Demonstrates Expansion of Cross-Reactive Memory B Cells

Strong differential regulation of serum and mucosal IgA responses as revealed in CD28-deficient mice using cholera toxin adjuvant

Strong, but Age-Dependent, Protection Elicited by a Deoxyribonucleic Acid/Modified Vaccinia Ankara Simian Immunodeficiency Virus Vaccine

Systems analysis of protective immune responses to RTS,S malaria vaccination in humans

Systems biology of vaccination for seasonal influenza in humans

Vaccine induction of antibodies and tissue-resident CD8+ T cells enhances protection against mucosal SHIV-infection in young macaques

Vaccine-induced plasmablast responses in rhesus macaques: phenotypic characterization and a source for generating antigen-specific monoclonal antibodies

Zika Virus Infects Human Placental Macrophages