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List of works by Bernard Hirschel

"The new Center will allow the professionalization of patient-oriented clinical research". Interview by Marina Casselyn, Michael Balavoine, Kiefer Bertrand

scientific article published in January 2008

A Controlled Study of Inhaled Pentamidine for Primary Prevention ofPneumocystis cariniiPneumonia

A Randomized Comparison of Second-Line Lopinavir/ Ritonavir Monotherapy versus Tenofovir/Lamivudine/ Lopinavir/Ritonavir in Patients Failing Nnrti Regimens: The HIV Star Study ⬇️

scientific article published on July 2, 2012

A comparison of initial antiretroviral therapy in the Swiss HIV Cohort Study and the recommendations of the International AIDS Society-USA.

scientific article

A controlled trial of granulocyte macrophage-colony stimulating factor during interruption of HAART.

scientific article published on July 2003

A new era of antiretroviral drug toxicity.

scientific article published on January 2009

A prospective study of efficacy and safety of once-daily saquinavir/ritonavir plus two nucleoside reverse transcriptase inhibitors in treatment-naive Thai patients.

scientific article

A prospective trial of structured treatment interruptions in human immunodeficiency virus infection

scientific article published in May 2003

A prospective, randomized trial of structured treatment interruption for patients with chronic HIV type 1 infection

scientific article published on 26 January 2005

A randomized comparison of second-line lopinavir/ritonavir monotherapy versus tenofovir/lamivudine/lopinavir/ritonavir in patients failing NNRTI regimens: the HIV STAR study

article

A randomized cross-over study to compare raltegravir and efavirenz (SWITCH-ER study).

scientific article

A randomized crossover study to compare efavirenz and etravirine treatment ⬇️

scientific article published on January 2, 2011

A randomized trial of simplified maintenance therapy with abacavir, lamivudine, and zidovudine in human immunodeficiency virus infection

scientific article

A validated assay by liquid chromatography-tandem mass spectrometry for the simultaneous quantification of elvitegravir and rilpivirine in HIV positive patients

scientific article

Abnormalities of body fat distribution in HIV-infected persons treated with antiretroviral drugs: The Swiss HIV Cohort Study

scientific article published in September 2002

Absence of resistance mutations in antiretroviral-naive patients treated with ritonavir-boosted saquinavir.

scientific article published on January 2006

Ambiguous nucleotide calls from population-based sequencing of HIV-1 are a marker for viral diversity and the age of infection

scientific article published on 10 January 2011

Antiretroviral Treatment and Osteonecrosis in Patients of the Swiss HIV Cohort Study: A Nested Case-Control Study

article

Antiretroviral treatment and osteonecrosis in patients of the Swiss HIV Cohort Study: a nested case-control study

scientific article published in September 2004

Antiretroviral treatment during pregnancy

Antiretroviral treatment outcome following genotyping in Thai children who failed dual nucleoside reverse transcriptase inhibitors

scientific article published on 21 August 2009

Association of pharmacogenetic markers with premature discontinuation of first-line anti-HIV therapy: an observational cohort study

scientific article

Biphasic decline of CD4 cell count during scheduled treatment interruptions

Body fat changes among antiretroviral-naive patients on PI- and NNRTI-based HAART in the Swiss HIV cohort study

scientific article

Brief report: incubation and duration of specific symptoms at acute retroviral syndrome as independent predictors of progression to AIDS.

scientific article published on April 2003

CD4 T-lymphocyte recovery in individuals with advanced HIV-1 infection receiving potent antiretroviral therapy for 4 years: the Swiss HIV Cohort Study

scientific article

CD4+ T cell count recovery in HIV type 1-infected patients is independent of class of antiretroviral therapy.

scientific article

CD4+ T-cell restoration after 48 weeks in the maraviroc treatment-experienced trials MOTIVATE 1 and 2.

scientific article published in August 2010

CD4-guided scheduled treatment interruptions compared with continuous therapy for patients infected with HIV-1: results of the Staccato randomised trial

scientific article published on August 2006

Capnocytophaga canimorsus prosthetic aortitis in an HIV-positive woman

scientific article published on 22 May 2013

Cellular Viral Rebound after Cessation of Potent Antiretroviral Therapy Predicted by Levels of Multiply Spliced HIV‐1 RNA Encodingnef

article

Changes in metabolic toxicity after switching from stavudine/didanosine to tenofovir/lamivudine--a Staccato trial substudy

scientific article

Choice of Initial Combination Antiretroviral Therapy in Individuals With HIV Infection: Determinants and Outcomes

scientific article published in September 2012

Clinical efficacy of early initiation of HAART in patients with asymptomatic HIV infection and CD4 cell count > 350 × 106/l

scientific article published in July 2002

Clinical features of acute retroviral syndrome differ by route of infection but not by gender and age.

scientific article published on November 2002

Cognitive dysfunction in HIV patients despite long-standing suppression of viremia

article

Comparative transcriptomics of extreme phenotypes of human HIV-1 infection and SIV infection in sooty mangabey and rhesus macaque

scientific article

Contribution of 20 single nucleotide polymorphisms of 13 genes to dyslipidemia associated with antiretroviral therapy.

scientific article

Contribution of genome-wide significant single-nucleotide polymorphisms and antiretroviral therapy to dyslipidemia in HIV-infected individuals: a longitudinal study

scientific article published on 18 September 2009

Correlates of self-reported nonadherence to antiretroviral therapy in HIV-infected patients: the Swiss HIV Cohort Study

scientific article published in March 2006

Determinants of sustained viral suppression in HIV-infected patients with self-reported poor adherence to antiretroviral therapy

scientific article

Diagnosing acute HIV infection

scientific article published on January 2012

Discontinuation of Primary Prophylaxis againstPneumocystis cariniiPneumonia in HIV-1–Infected Adults Treated with Combination Antiretroviral Therapy

article

Discontinuation of enfuvirtide in heavily pretreated HIV-infected individuals

scientific article published in July 2009

Divergent adaptation of hepatitis C virus genotypes 1 and 3 to human leukocyte antigen-restricted immune pressure

scientific article

Dose-dependent influence of didanosine on immune recovery in HIV-infected patients treated with tenofovir

scientific article published in November 2005

Drug resistance mutations during structured treatment interruptions

scientific article published in October 2003

Durability and outcome of initial antiretroviral treatments received during 2000--2005 by patients in the Swiss HIV Cohort Study

scientific article published on June 2008

Early antiretroviral therapy during primary HIV-1 infection results in a transient reduction of the viral setpoint upon treatment interruption

scientific article (publication date: 2011)

Ecological study of the predictors of successful management of dyslipidemia in HIV-infected patients on ART: the Swiss HIV Cohort Study

scientific article published in March 2007

Ecthyma Gangrenosum: Escherichia coli or Pseudomonas aeruginosa?

scientific article

Effect of early antiretroviral therapy during primary HIV-1 infection on cell-associated HIV-1 DNA and plasma HIV-1 RNA.

scientific article published in January 2011

Effect of rimonabant on weight reduction and cardiovascular risk

scientific article

Efficacy of a twice-daily antiretroviral regimen containing 100 mg ritonavir/400 mg indinavir in HIV-infected patients, by Ghosn et al.

scientific article published in January 2003

Emergence of HIV-1 drug resistance in previously untreated patients initiating combination antiretroviral treatment: a comparison of different regimen types

scientific article published on September 2007

Emergence of minor populations of human immunodeficiency virus type 1 carrying the M184V and L90M mutations in subjects undergoing structured treatment interruptions

scientific article published on 3 November 2003

Estimating the net contribution of interleukin-28B variation to spontaneous hepatitis C virus clearance

scientific article

Etravirine and Rilpivirine Resistance in HIV-1 Subtype Crf01_Ae-Infected Adults Failing Non-Nucleoside Reverse Transcriptase Inhibitor-Based Regimens ⬇️

scientific article published on January 1, 2011

Factors associated with the emergence of K65R in patients with HIV-1 infection treated with combination antiretroviral therapy containing tenofovir

scientific article published in April 2008

Failure to detect xenotropic murine leukemia virus-related virus in blood of individuals at high risk of blood-borne viral infections

scientific article

Failures of 1 week on, 1 week off antiretroviral therapies in a randomized trial

scientific article published in October 2003

Frequency and determinants of unprotected sex among HIV-infected persons: the Swiss HIV cohort study

scientific article published on 29 October 2010

Functional discrepancies in HIV-specific CD8+ T-lymphocyte populations are related to plasma virus load

scientific article published in November 2002

Genetic variation in IL28B is associated with chronic hepatitis C and treatment failure: a genome-wide association study

scientific article

Glitazones in lipodystrophy syndrome induced by highly active antiretroviral therapy

scientific article published in March 2003

HIV RNA in plasma rebounds within days during structured treatment interruptions

scientific article published in January 2003

HIV drugs for treatment, and for prevention

scientific article published on 26 May 2010

HIV increases markers of cardiovascular risk: results from a randomized, treatment interruption trial

scientific article published in May 2009

HIV rebounds from latently infected cells, rather than from continuing low-level replication

scholarly article

HIV transmission under highly active antiretroviral therapy

scientific article published in November 2008

HIV treatment for prevention

scientific article

HIV viral load monitoring in resource-limited regions: optional or necessary?

scientific article published on 28 November 2006

HIV-1 genital shedding in HIV-infected patients randomized to second-line lopinavir/ritonavir monotherapy versus tenofovir/lamivudine/lopinavir/ritonavir

scientific article published on 24 January 2014

HIV-AIDS 2008: the year in review

scientific article published in January 2009

HLA-Bw4 homozygosity is associated with an impaired CD4 T cell recovery after initiation of antiretroviral therapy.

scientific article published in June 2008

Health perceptions of African HIV-infected patients and their physicians

scientific article published on 30 November 2009

Hierarchical modeling gave plausible estimates of associations between metabolic syndrome and components of antiretroviral therapy

scientific article

Higher memory responses in HIV-infected and kidney transplanted patients than in healthy subjects following priming with the pandemic vaccine

scientific article

Highly active antiretroviral therapy (HAART) retreatment in patients on CD4-guided therapy achieved similar virologic suppression compared with patients on continuous HAART: the HIV Netherlands Australia Thailand Research Collaboration 001.4 study

scientific article published in August 2005

Human herpes virus 8 replication during disseminated tuberculosis in a man with human immunodeficiency virus: a case report

scientific article

Human herpes virus type 8 seroprevalence in pregnant women in Geneva, Switzerland

scientific article published on 23 June 2010

Human immunodeficiency virus-specific CD8(+) T-cell responses do not predict viral growth and clearance rates during structured intermittent antiretroviral therapy

scientific article

Humoral immunity to HIV-1: kinetics of antibody responses in chronic infection reflects capacity of immune system to improve viral set point

scientific article published on 8 June 2004

Immunological recovery and antiretroviral therapy in HIV-1 infection

scientific article

Impact of highly active antiretroviral therapy on the molecular epidemiology of newly diagnosed HIV infections

scientific article published in October 2012

Impact of occasional short interruptions of HAART on the progression of HIV infection: results from a cohort study

article

Impact of previous virological treatment failures and adherence on the outcome of antiretroviral therapy in 2007.

scientific article published on 14 December 2009

Impact of single nucleotide polymorphisms and of clinical risk factors on new‐onset diabetes mellitus in HIV‐infected individuals

scientific article

Imported cases of histoplasmosis

scientific article published in November 2009

Improved sensitivity of an interferon-gamma release assay (T-SPOT.TB™) in combination with tuberculin skin test for the diagnosis of latent tuberculosis in the presence of HIV co-infection

scientific article

Improved virological outcome in White patients infected with HIV-1 non-B subtypes compared to subtype B.

scientific article published on 13 October 2011

Incidence and risk factors for chronic elevation of alanine aminotransferase levels in HIV-infected persons without hepatitis b or c virus co-infection

scientific article published in February 2010

Incidence of HIV-1 Drug Resistance Among Antiretroviral Treatment–Naive Individuals Starting Modern Therapy Combinations ⬇️

scientific article published on November 4, 2011

Increased incidence of sexually transmitted infections in Geneva, Switzerland

scientific article

Increased mortality after a first myocardial infarction in human immunodeficiency virus-infected patients; a nested cohort study

scientific article

Infrequent replication of parvovirus B19 and erythrovirus genotypes 2 and 3 among HIV-infected patients with chronic anemia.

scientific article

Infrequent transmission of HIV-1 drug-resistant variants.

scientific article

Initial treatment for HIV infection--an embarrassment of riches

scientific article published in May 2008

Intermittent and sustained low-level HIV viral rebound in patients receiving potent antiretroviral therapy

article

Interrupting highly active antiretroviral therapy in patients with HIV.

scientific article

Interruptions of cART limits CD4 T-cell recovery and increases the risk for opportunistic complications and death.

scientific article published in February 2011

Interruptions of tenofovir/emtricitabine-based antiretroviral therapy in patients with HIV/hepatitis B virus co-infection

scientific article published in January 2008

Is autovaccination dead?

scientific article published in January 2003

Is unsafe sexual behaviour increasing among HIV-infected individuals?

scientific article published in August 2004

Kidney light chain disease in patients with the acquired immunodeficiency syndrome

scientific article

L-ornithine alpha-ketoglutarate in HIV infection: effects on muscle, gastrointestinal, and immune functions

scientific article

Late presentation of HIV-infected individuals

scientific article published on January 2007

Lipid profiles for antiretroviral-naive patients starting PI- and NNRTI-based therapy in the Swiss HIV cohort study.

scientific article

Long-Term Efficacy, Safety, and Tolerability of Indinavir-Based Therapy in Protease Inhibitor--Naive Adults with Advanced HIV Infection ⬇️

scientific article published on September 18, 2003

Long-term efficacy and safety of first-line therapy with once-daily saquinavir/ritonavir

scientific article published in January 2008

Long-term trends of HIV type 1 drug resistance prevalence among antiretroviral treatment-experienced patients in Switzerland

scientific article published in April 2009

Longitudinal analysis of patterns and predictors of changes in self-reported adherence to antiretroviral therapy: Swiss HIV Cohort Study

scientific article published in June 2010

Low bone mineral density, renal dysfunction, and fracture risk in HIV infection: a cross-sectional study

scientific article published in December 2009

Low human immunodeficiency virus envelope diversity correlates with low in vitro replication capacity and predicts spontaneous control of plasma viremia after treatment interruptions

scientific article

Micro-structural brain alterations in aviremic HIV+ patients with minor neurocognitive disorders: a multi-contrast study at high field

scientific article

Migrants from Sub-Saharan Africa in the Swiss HIV Cohort Study: access to antiretroviral therapy, disease progression and survival

scientific article

Modeling the influence of APOC3, APOE, and TNF polymorphisms on the risk of antiretroviral therapy-associated lipid disorders

scientific article

Molecular epidemiology reveals long-term changes in HIV type 1 subtype B transmission in Switzerland

scientific article published in May 2010

Nadir CD4 count and monthly income predict cervical squamous cell abnormalities in HIV-positive women in a resource-limited setting

scientific article published in August 2008

Neurocognitive impairment in patients randomized to second-line lopinavir/ritonavir-based antiretroviral therapy vs. lopinavir/ritonavir monotherapy ⬇️

scientific article published on September 20, 2012

New drugs, old drugs - dear drugs, cheap drugs

scientific article published in June 2002

No longitudinal mitochondrial DNA sequence changes in HIV-infected individuals with and without lipoatrophy

scientific article

Phylogenetic approach reveals that virus genotype largely determines HIV set-point viral load

scientific article published on 30 September 2010

Predicting the evolution of Kaposi sarcoma, in the highly active antiretroviral therapy era

Predictors of optimal viral suppression in patients switched to abacavir, lamivudine, and zidovudine: the Swiss HIV Cohort Study

scientific article published in October 2007

Proviral HIV-DNA predicts viral rebound and viral setpoint after structured treatment interruptions

article

Quantifiable cytotoxic T lymphocyte responses and HLA-related risk of progression to AIDS

scholarly article

Questions about the antimalarial amodiaquine

scientific article published in April 2003

Randomized controlled study demonstrating failure of LPV/r monotherapy in HIV: the role of compartment and CD4-nadir ⬇️

scientific article published on September 24, 2010

Reducing tuberculosis incidence by tuberculin skin testing, preventive treatment, and antiretroviral therapy in an area of low tuberculosis transmission

scientific article published on 28 November 2006

Relevance of HIV-1-specific CD4+ helper T-cell responses during structured treatment interruptions in patients with CD4+ T-cell nadir above 400/mm3.

scientific article published in July 2004

Replicative phenotyping adds value to genotypic resistance testing in heavily pre-treated HIV-infected individuals--the Swiss HIV Cohort Study

scientific article

Residual HIV-specific CD4 and CD8 T cell frequencies after prolonged antiretroviral therapy reflect pretreatment plasma virus load

scientific article published in November 2002

Review on structured treatment interruptions (STIs).

scientific article published in February 2007

Risk of influenza-like illness in an acute health care setting during community influenza epidemics in 2004-2005, 2005-2006, and 2006-2007: a prospective study

scientific article

Rivastigmine for HIV-associated neurocognitive disorders: a randomized crossover pilot study

scientific article published on 23 January 2013

Role of retroviral restriction factors in the interferon-α-mediated suppression of HIV-1 in vivo

scientific article published on 6 February 2012

Safety and efficacy of once-daily nevirapine dosing: a multicohort study

scientific article published in January 2009

Saquinavir trough concentration before and after switching NRTI to tenofovir in patients treated with once-daily saquinavir hard gel capsule/ritonavir 1600 mg/100 mg.

scientific article published in December 2004

Screening and isolation to control meticillin-resistant Staphylococcus aureus: sense, nonsense, and evidence

scientific article published on 20 August 2014

Severe leptospirosis with multiple organ failure successfully treated by plasma exchange and high-volume hemofiltration

scientific article published on 13 September 2011

Short-term clinical disease progression in HIV-1-positive patients taking combination antiretroviral therapy: the EuroSIDA risk-score.

scientific article published in September 2007

Small Dense Lipoproteins, Apolipoprotein B, and Risk of Coronary Events in HIV-Infected Patients on Antiretroviral Therapy

article

Stable partnership and progression to AIDS or death in HIV infected patients receiving highly active antiretroviral therapy: Swiss HIV cohort study

scientific article

Stimulation of HIV-specific cellular immunity by structured treatment interruption fails to enhance viral control in chronic HIV infection

scientific article

Structured treatment interruptions in HIV infection: benefit or disappointment?

scientific article published in June 2003

Subgroup analyses of maraviroc in previously treated R5 HIV-1 infection

scientific article

Substitution for protease inhibitors in HIV therapy

scientific article published in December 2003

Successful efavirenz dose reduction guided by therapeutic drug monitoring

scientific article published in January 2011

Supersensitive Viral Load Assay in Predicting CD4-Guided Treatment Failure

scientific article published on 16 October 2008

Supervised interruptions of antiretroviral therapy ⬇️

scientific article published on January 1, 2002

Switch to etravirine for HIV-positive patients receiving statin treatment: a prospective study

scientific article

Switching from protease inhibitors to efavirenz: differences in efficacy and tolerance among risk groups: a case-control study from the Swiss HIV Cohort

scientific article published on February 2002

Systemic antibody responses to gut commensal bacteria during chronic HIV-1 infection

scientific article published on 21 April 2011

The impact of combination antiretroviral therapy and its interruption on anxiety, stress, depression and quality of life in Thai patients

scientific article published on 15 September 2009

The impact of transmission clusters on primary drug resistance in newly diagnosed HIV-1 infection

scientific article

The individualized genetic barrier predicts treatment response in a large cohort of HIV-1 infected patients

scientific article (publication date: 2013)

The prevalence of erectile dysfunction and its association with antiretroviral therapy in HIV-infected men: the Swiss HIV Cohort Study

scientific article published on 12 September 2012

The role of CFTR and SPINK-1 mutations in pancreatic disorders in HIV-positive patients: a case-control study

scientific article published in July 2004

The role of compartment penetration in PI-Monotherapy: the Atazanavir-Ritonavir Monomaintenance (ATARITMO) Trial

The role of migration and domestic transmission in the spread of HIV-1 non-B subtypes in Switzerland

scientific article published in October 2011

The trap: professional exposure to human immunodeficiency virus antibody negative blood with high viral load

scientific article published in December 2007

Topical tacrolimus for effective treatment of eosinophilic folliculitis associated with human immunodeficiency virus infection

scientific article published in October 2005

Treatment modification in human immunodeficiency virus-infected individuals starting combination antiretroviral therapy between 2005 and 2008.

scientific article published in January 2010

Treatment of Clostridium difficile infection in a French university hospital

scientific article

Tuberculous Cutaneous Ulcers Associated with Miliary Tuberculosis in an Elderly Woman

scientific article published on 28 August 2009

Unsafe sex and increased incidence of hepatitis C virus infection among HIV-infected men who have sex with men: the Swiss HIV Cohort Study

scientific article

Unusual primary HIV infection with colonic ulcer complicated by hemorrhagic shock: a case report

scientific article published on 20 August 2010

Viral Suppression Rates in Salvage Treatment With Raltegravir Improved With the Administration of Genotypic Partially Active or Inactive Nucleoside/Tide Reverse Transcriptase Inhibitors

Viral resuppression and detection of drug resistance following interruption of a suppressive non-nucleoside reverse transcriptase inhibitor-based regimen

scientific article

Virological and immunological responses to efavirenz or boosted lopinavir as first-line therapy for patients with HIV.

scientific article published in January 2009

Weight-losing HIV-infected patients on recombinant human growth hormone for 12 wk: a national study

scientific article

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