List of works by Mark G. Lewis

A DNA vaccine against chikungunya virus is protective in mice and induces neutralizing antibodies in mice and nonhuman primates

scientific article

A highly intensified ART regimen induces long-term viral suppression and restriction of the viral reservoir in a simian AIDS model

scientific article

A virus-like particle vaccine for epidemic Chikungunya virus protects nonhuman primates against infection

scientific article

Activation drives PD-1 expression during vaccine-specific proliferation and following lentiviral infection in macaques

scientific article

Ad26/MVA therapeutic vaccination with TLR7 stimulation in SIV-infected rhesus monkeys

scientific article

An Enzyme-Linked Immunosorbent Assay (ELISA) for Methylphenidate (Ritalin(R)) in Urine ⬇️

scientific article published on September 1, 2003

An enzyme-linked immunosorbent assay for corticosteroid-binding globulin using monoclonal and polyclonal antibodies: decline in CBG following synthetic ACTH.

scientific article

An optimized SIV DNA vaccine can serve as a boost for Ad5 and provide partial protection from a high-dose SIVmac251 challenge

scientific article published on 8 March 2012

Animal models for COVID-19

scientific article published on 23 September 2020

Antibody and TLR7 agonist delay viral rebound in SHIV-infected monkeys

scientific article published in Nature

Antibody-mediated protection against SHIV challenge includes systemic clearance of distal virus

scientific article published on 18 August 2016

CD8+ cell depletion of SHIV89.6P-infected macaques induces CD4+ T cell proliferation that contributes to increased viral loads

scientific article published on 28 September 2009

Cellular immunity elicited by human immunodeficiency virus type 1/ simian immunodeficiency virus DNA vaccination does not augment the sterile protection afforded by passive infusion of neutralizing antibodies

scientific article published on October 2003

Characterization of founder viruses in very early SIV rectal transmission

scientific article

Chronic simian immunodeficiency virus infection is associated with contrasting phenotypes of dysfunctional Bcl6 germinal center B cells or Bcl6 Bcl2 non-germinal center B cells

scholarly article by Olusegun O Onabajo et al published November 2018 in Journal of Cellular and Molecular Medicine

Correlates of Protection Against SIVmac251 Infection in Rhesus Macaques Immunized With Chimpanzee-Derived Adenovirus Vectors.

scientific article published on 4 March 2018

Corrigendum to: Infection of monkeys by simian-human immunodeficiency viruses with transmitted/founder clade C HIV-1 envelopes [Virology 475 (2015) 37–45]

article

Corrigendum: Zika viral dynamics and shedding in rhesus and cynomolgus macaques

scientific article published on February 2017

DNA encoding an HIV-1 Gag/human lysosome-associated membrane protein-1 chimera elicits a broad cellular and humoral immune response in Rhesus macaques

scientific article

DNA vaccine protection against SARS-CoV-2 in rhesus macaques

scientific article published on 20 May 2020

Durability and correlates of vaccine protection against Zika virus in rhesus monkeys.

scientific article published in December 2017

Early establishment and antigen dependence of simian immunodeficiency virus-specific CD8+ T-cell defects

scientific article

Effect of chronic morphine administration on circulating T cell population dynamics in rhesus macaques

scientific article published on 20 September 2013

Effect of chronic morphine administration on circulating dendritic cells in SIV-infected rhesus macaques

scientific article published on 16 April 2016

Effects of antibody on viral kinetics in simian/human immunodeficiency virus infection: implications for vaccination

scientific article published on May 2004

Electroporation of synthetic DNA antigens offers protection in nonhuman primates challenged with highly pathogenic avian influenza virus

scientific article published on 11 February 2009

Enhanced potency of plasmid DNA microparticle human immunodeficiency virus vaccines in rhesus macaques by using a priming-boosting regimen with recombinant proteins

scientific article published on July 2005

Enhancement of DNA vaccine potency in rhesus macaques by electroporation

scientific article published in June 2004

Envelope residue 375 substitutions in simian-human immunodeficiency viruses enhance CD4 binding and replication in rhesus macaques

scientific article published on 31 May 2016

Evaluation of a multivalent vaccine against lymphatic filariasis in rhesus macaque model

scientific article

Evaluation of the mRNA-1273 Vaccine against SARS-CoV-2 in Nonhuman Primates

scientific article published on 28 July 2020

Eventual AIDS vaccine failure in a rhesus monkey by viral escape from cytotoxic T lymphocytes

scientific article published in Nature

Fetal Neuropathology in Zika Virus-Infected Pregnant Female Rhesus Monkeys

scientific article published on 28 March 2018

Full-length HIV-1 immunogens induce greater magnitude and comparable breadth of T lymphocyte responses to conserved HIV-1 regions compared with conserved-region-only HIV-1 immunogens in rhesus monkeys

scientific article published on 15 August 2012

Gold drug auranofin restricts the viral reservoir in the monkey AIDS model and induces containment of viral load following ART suspension

scientific article published in July 2011

High attenuation and immunogenicity of a simian immunodeficiency virus expressing a proteolysis-resistant inhibitor of NF-kappaB.

scientific article published on 30 October 2003

High dose of plasmid IL-15 inhibits immune responses in an influenza non-human primates immunogenicity model

scientific article

IL-15 treatment during acute simian immunodeficiency virus (SIV) infection increases viral set point and accelerates disease progression despite the induction of stronger SIV-specific CD8+ T cell responses

scientific article published on January 2008

IL-28B/IFN-lambda 3 drives granzyme B loading and significantly increases CTL killing activity in macaques

scientific article

Immune correlates of protection by mRNA-1273 vaccine against SARS-CoV-2 in nonhuman primates

scientific article

Immunogenicity of HIV virus-like particles in rhesus macaques by intranasal administration

scientific article

Immunogenicity of attenuated vesicular stomatitis virus vectors expressing HIV type 1 Env and SIV Gag proteins: comparison of intranasal and intramuscular vaccination routes

scientific article published in September 2004

Impact of antiretroviral treatment on gene expression in peripheral blood mononuclear cells from SIVmac251-infected macaques

scientific article published on 25 June 2007

Impact of vaccine-induced mucosal high-avidity CD8+ CTLs in delay of AIDS viral dissemination from mucosa

scientific article published on 22 December 2005

Impact of viral infection on the gene expression profiles of proliferating normal human peripheral blood mononuclear cells infected with HIV type 1 RF.

scientific article published on February 2002

Improved vaccine protection from simian AIDS by the addition of nonstructural simian immunodeficiency virus genes

scientific article published in January 2006

Independence of granzyme B secretion and interferon- gamma production during acute simian immunodeficiency virus infection

scientific article published on 14 April 2006

Infection of monkeys by simian-human immunodeficiency viruses with transmitted/founder clade C HIV-1 envelopes

scientific article published on 22 November 2014

Interleukin-15 but not interleukin-7 abrogates vaccine-induced decrease in virus level in simian immunodeficiency virus mac251-infected macaques

scientific article published in March 2007

Interleukin-15 increases effector memory CD8+ t cells and NK Cells in simian immunodeficiency virus-infected macaques

scientific article published on April 2005

Introduction of the YTE mutation into the non-immunogenic HIV bnAb PGT121 induces anti-drug antibodies in macaques

article

Investigational treatment suspension and enhanced cell-mediated immunity at rebound followed by drug-free remission of simian AIDS.

scientific article published on 16 July 2013

Lack of therapeutic efficacy of an antibody to α4β7 in SIVmac251-infected rhesus macaques

scientific article published on 05 September 2019

Long-term programming of antigen-specific immunity from gene expression signatures in the PBMC of rhesus macaques immunized with an SIV DNA vaccine

scientific article (publication date: 2011)

Modeling a safer smallpox vaccination regimen, for human immunodeficiency virus type 1-infected patients, in immunocompromised macaques

scientific article published on 10 October 2003

Mucosal and peripheral Lin- HLA-DR+ CD11c/123- CD13+ CD14- mononuclear cells are preferentially infected during acute simian immunodeficiency virus infection

scientific article published on 16 November 2011

Neutralizing antibody responses in macaques induced by human immunodeficiency virus type 1 monovalent or trivalent envelope glycoproteins

scientific article

Outcome of simian-human immunodeficiency virus strain 89.6p challenge following vaccination of rhesus macaques with human immunodeficiency virus Tat protein

scientific article published on April 2002

Pattern of SIVagm infection in patas monkeys suggests that host adaptation to simian immunodeficiency virus infection may result in resistance to infection and virus extinction

scientific article

Patterns of gene expression in peripheral blood mononuclear cells of rhesus macaques infected with SIVmac251 and exhibiting differential rates of disease progression

scientific article

Pharmacokinetics and immunogenicity of broadly neutralizing HIV monoclonal antibodies in macaques

scientific article

Plasmodium inui infection reduces the efficacy of a simian immunodeficiency virus DNA vaccine in a rhesus macaque model through alteration of the vaccine-induced immune response

scientific article

Prevention of SIVmac251 reservoir seeding in rhesus monkeys by early antiretroviral therapy

scientific article published in Nature Communications

Prior Exposure to Zika Virus Significantly Enhances Peak Dengue-2 Viremia in Rhesus Macaques

scientific article published on 5 September 2017

Protection against SARS-CoV-2 infection by a mucosal vaccine in rhesus macaques

scientific article published in 2021

Protection against SHIV Challenge by Subcutaneous Administration of the Plant-Derived PGT121 Broadly Neutralizing Antibody in Macaques

scientific article

Protection against simian/human immunodeficiency virus (SHIV) 89.6P in macaques after coimmunization with SHIV antigen and IL-15 plasmid

scholarly article

Protection of rhesus monkeys against infection with minimally pathogenic simian-human immunodeficiency virus: correlations with neutralizing antibodies and cytotoxic T cells

scientific article

Protective antibodies elicited by SARS-CoV-2 spike protein vaccination are boosted in the lung after challenge in nonhuman primates

Protective efficacy of adenovirus/protein vaccines against SIV challenges in rhesus monkeys

scientific article

Publisher Correction: Antibody and TLR7 agonist delay viral rebound in SHIV-infected monkeys

scientific article published in Nature

REGN-COV2 antibodies prevent and treat SARS-CoV-2 infection in rhesus macaques and hamsters

scientific article published on 09 October 2020

Rapid Inflammasome Activation following Mucosal SIV Infection of Rhesus Monkeys

scientific article published on 11 April 2016

Rapid development of a DNA vaccine for Zika virus

scientific article

Rapid seeding of the viral reservoir prior to SIV viraemia in rhesus monkeys

scientific article

Recapitulation of HIV-1 Env-antibody coevolution in macaques leading to neutralization breadth

scientific article published on 19 November 2020

Recombinant chimeric virus with wild-type dengue 4 virus premembrane and envelope and virulent yellow fever virus Asibi backbone sequences is dramatically attenuated in nonhuman primates

scientific article

Recombinant interleukin-7 induces proliferation of naive macaque CD4+ and CD8+ T cells in vivo

scientific article published on September 2004

Response of a simian immunodeficiency virus (SIVmac251) to raltegravir: a basis for a new treatment for simian AIDS and an animal model for studying lentiviral persistence during antiretroviral therapy

scientific article

Rhesus macaque lymph node PD-1(hi)CD4+ T cells express high levels of CXCR5 and IL-21 and display a CCR7(lo)ICOS+Bcl6+ T-follicular helper (Tfh) cell phenotype

scientific article

SARS-CoV-2 infection protects against rechallenge in rhesus macaques

scientific article

SIV Infection of Lung Macrophages

scientific article published on May 2015

Significant Depletion of CD4(+) T Cells Occurs in the Oral Mucosa during Simian Immunodeficiency Virus Infection with the Infected CD4(+) T Cell Reservoir Continuing to Persist in the Oral Mucosa during Antiretroviral Therapy

scientific article published on 30 April 2015

Simultaneous Coinfection of Macaques with Zika and Dengue Viruses Does not Enhance Acute Plasma Viremia but Leads to Activation of Monocyte Subsets and Biphasic Release of Pro-inflammatory Cytokines

scientific article published on 27 May 2019

Smallpox vaccine does not protect macaques with AIDS from a lethal monkeypox virus challenge

scientific article

Suppression of transforming growth factor β receptor 2 and Smad5 is associated with high levels of microRNA miR-155 in the oral mucosa during chronic simian immunodeficiency virus infection

scientific article

Sustained suppression of SHIV89.6P replication in macaques by vaccine-induced CD8+ memory T cells.

scientific article published in September 2008

Systemic immunization with CCL27/CTACK modulates immune responses at mucosal sites in mice and macaques

scientific article

T-cell receptor excision circles (TREC) in SHIV 89.6p and SIVmac251 models of HIV-1 infection

scientific article published in January 2004

TLR7 agonists induce transient viremia and reduce the viral reservoir in SIV-infected rhesus macaques on antiretroviral therapy.

scientific article

Targeted selection of HIV-specific antibody mutations by engineering B cell maturation

scientific article

Therapeutic efficacy of an Ad26/MVA vaccine with SIV gp140 protein and vesatolimod in ART-suppressed rhesus macaques

scientific article published on 18 May 2022

Therapeutic efficacy of potent neutralizing HIV-1-specific monoclonal antibodies in SHIV-infected rhesus monkeys

scientific article

Therapeutic vaccination with simian immunodeficiency virus (SIV)-DNA + IL-12 or IL-15 induces distinct CD8 memory subsets in SIV-infected macaques

scientific article published in June 2008

Two-Year Follow-Up of Macaques Developing Intermittent Control of the Human Immunodeficiency Virus Homolog Simian Immunodeficiency Virus SIVmac251 in the Chronic Phase of Infection

scientific article published on 13 May 2015

Type I interferon upregulates Bak and contributes to T cell loss during human immunodeficiency virus (HIV) infection

scientific article

Unique Th1/Th2 Phenotypes Induced during Priming and Memory Phases by Use of Interleukin-12 (IL-12) or IL-28B Vaccine Adjuvants in Rhesus Macaques ⬇️

scientific article published on August 4, 2010

Use of interleukin 15 to enhance interferon-gamma production by antigen-specific stimulated lymphocytes from rhesus macaques.

scientific article published in August 2003

Vaccination of macaques with long-standing SIVmac251 infection lowers the viral set point after cessation of antiretroviral therapy.

scientific article published in November 2002

Viral reservoir is suppressed but not eliminated by CD8 vaccine specific lymphocytes

scientific article published in February 2010

Zika Virus Persistence in the Central Nervous System and Lymph Nodes of Rhesus Monkeys

scientific article (publication date: April 2017)

Zika convalescent macaques display delayed induction of anmanestic cross-neutralizing antibody responses after dengue infection.

scientific article published on 13 July 2018

Zika viral dynamics and shedding in rhesus and cynomolgus macaques

scientific article (publication date: December 2016)

Zika virus protection by a single low-dose nucleoside-modified mRNA vaccination

scientific article

mRNA-1273 protects against SARS-CoV-2 beta infection in nonhuman primates

scholarly article by Kizzmekia Corbett et al published 20 August 2021 in Nature Immunology

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