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List of works by Xiangguo Qiu

A Role for Fc Function in Therapeutic Monoclonal Antibody-Mediated Protection against Ebola Virus

scientific article published on 01 August 2018

A Single Dose Respiratory Recombinant Adenovirus-Based Vaccine Provides Long-Term Protection for Non-Human Primates from Lethal Ebola Infection

scientific article published on 14 November 2014

A Two-Antibody Pan-Ebolavirus Cocktail Confers Broad Therapeutic Protection in Ferrets and Nonhuman Primates

scientific article published in 2019

Adenovirus-Vectored Vaccine Provides Postexposure Protection to Ebola Virus-Infected Nonhuman Primates

scientific article

An Adenovirus Vaccine Expressing Ebola Virus Variant Makona Glycoprotein Is Efficacious in Guinea Pigs and Nonhuman Primates

scientific article published on 4 August 2016

Analysis of the expressed heavy chain variable-region genes of Macaca fascicularis and isolation of monoclonal antibodies specific for the Ebola virus' soluble glycoprotein

scientific article

Antibodies from a Human Survivor Define Sites of Vulnerability for Broad Protection against Ebolaviruses.

scientific article published on May 2017

Antibody Treatment of Ebola and Sudan Virus Infection via a Uniquely Exposed Epitope within the Glycoprotein Receptor-Binding Site

scientific article published on 4 May 2016

Antibody therapeutics for Ebola virus disease

scientific article published on 27 January 2016

Antibody therapy for Ebola: is the tide turning around?

scientific article published on 06 February 2014

Antiviral activity of quercetin-3-β-O-D-glucoside against Zika virus infection.

scientific article published on 5 September 2017

Assessing Antiviral Countermeasures Using Mouse Models of Ebolavirus Infection

scientific article published on January 2017

Assessment of the potential for host-targeted iminosugars UV-4 and UV-5 activity against filovirus infections in vitro and in vivo

scientific article published on 28 November 2016

Can Ebola virus become endemic in the human population?

scientific article

Cellular-Beacon-Mediated Counting for the Ultrasensitive Detection of Ebola Virus on an Integrated Micromagnetic Platform

scientific article published in 2018

Characterization of Reston virus infection in ferrets

scientific article published on 02 March 2019

Characterization of Sudan Ebolavirus infection in ferrets

scientific article published on 8 May 2017

Characterization of Zaire ebolavirus glycoprotein-specific monoclonal antibodies ⬇️

scientific article published on August 31, 2011

Characterization of a Bivalent Vaccine Capable of Inducing Protection Against Both Ebola and Cross-clade H5N1 Influenza in Mice

scientific article

Characterization of host immune responses in Ebola virus infections

scientific article published on 18 April 2014

Clinical Evaluation of Ebola Virus Disease Therapeutics

scientific article

Complete protection of the BALB/c and C57BL/6J mice against Ebola and Marburg virus lethal challenges by pan-filovirus T-cell epigraph vaccine

scientific article published on 28 February 2019

Comprehensive functional analysis of N-linked glycans on Ebola virus GP1.

scientific article published on 28 January 2014

Computer-Aided Discovery and Characterization of Novel Ebola Virus Inhibitors.

scientific article published on 6 April 2018

Cooperativity Enables Non-neutralizing Antibodies to Neutralize Ebolavirus

scientific article published on April 2017

Correction to: Impact of intensive care unit supportive care on the physiology of Ebola virus disease in a universally lethal non-human primate model

scientific article published on 04 December 2019

Deep-sequencing of Marburg virus genome during sequential mouse passaging and cell-culture adaptation reveals extensive changes over time

scientific article

Delivering Prolonged Intensive Care to a Non-human Primate: A High Fidelity Animal Model of Critical Illness

scientific article

Designing Efficacious Vesicular Stomatitis Virus-Vectored Vaccines Against Ebola Virus

scientific article

Development and Characterization of a Guinea Pig-Adapted Sudan Virus

scientific article

Development of a Human Antibody Cocktail that Deploys Multiple Functions to Confer Pan-Ebolavirus Protection

scientific article published in 2019

Development of an antigen detection assay for early point-of-care diagnosis of Zaire ebolavirus

scientific article published on 03 November 2020

Development of experimental and early investigational drugs for the treatment of Ebola virus infections

scientific article published on 12 June 2015

Diagnostic strategies for Ebola virus detection

scientific article published in March 2016

Ebola GP-specific monoclonal antibodies protect mice and guinea pigs from lethal Ebola virus infection

scientific article published on 20 March 2012

Ebola viral load at diagnosis associates with patient outcome and outbreak evolution

scientific article

Ebola virus infection kinetics in chimeric mice reveal a key role of T cells as barriers for virus dissemination

scientific article published on 03 March 2017

Ebola virus transmission in guinea pigs

scientific article

Emetine inhibits Zika and Ebola virus infections through two molecular mechanisms: inhibiting viral replication and decreasing viral entry.

scientific article published on 5 June 2018

Equine immunoglobulin F(ab') fragments protect mice from Rift Valley fever virus infection

scientific article published on 07 September 2018

Equine-Origin Immunoglobulin Fragments Protect Nonhuman Primates from Ebola Virus Disease

Establishment and characterization of a lethal mouse model for the Angola strain of Marburg virus

scientific article

Evaluation of transmission risks associated with in vivo replication of several high containment pathogens in a biosafety level 4 laboratory

scientific article published on 25 July 2014

Ferrets Infected with Bundibugyo Virus or Ebola Virus Recapitulate Important Aspects of Human Filovirus Disease

scientific article published on 03 August 2016

From bench to almost bedside: the long road to a licensed Ebola virus vaccine

scientific article published on 17 November 2017

Funding vaccines for emerging infectious diseases

scientific article published in December 2017

Gene Transfer of ZMapp Antibodies Mediated By Recombinant Adeno-Associated Virus Protects Against Ebola Infections

scientific article published on 27 November 2017

Generation and Characterization of Anti-Filovirus Nucleoprotein Monoclonal Antibodies

scholarly article by Md Niaz Rahim et al published 14 March 2019 in Viruses

Identification of a clinical compound losmapimod that blocks Lassa virus entry

scientific article published on 04 April 2019

Immune Response to Marburg Virus Angola Infection in Nonhuman Primates

scientific article published on 9 May 2015

Immune parameters correlate with protection against ebola virus infection in rodents and nonhuman primates

scientific article published on October 2012

Immunization with vesicular stomatitis virus vaccine expressing the Ebola glycoprotein provides sustained long-term protection in rodents

scientific article published on 27 August 2014

Immunization-Elicited Broadly Protective Antibody Reveals Ebolavirus Fusion Loop as a Site of Vulnerability.

scientific article published on May 2017

Impact of intensive care unit supportive care on the physiology of Ebola virus disease in a universally lethal non-human primate model

scientific article published on 13 September 2019

In Vivo Delivery of Synthetic Human DNA-Encoded Monoclonal Antibodies Protect against Ebolavirus Infection in a Mouse Model

scientific article published on 01 November 2018

Inactivation of Zaire ebolavirus Variant Makona in Human Serum Samples Analyzed by Enzyme-Linked Immunosorbent Assay

scientific article published on 28 August 2016

Incorporation of Ebola glycoprotein into HIV particles facilitates dendritic cell and macrophage targeting and enhances HIV-specific immune responses

article

Intra-host Ebola viral adaption during human infection

scientific article published on 20 February 2019

Intramuscular Adeno-Associated Virus-Mediated Expression of Monoclonal Antibodies Provides 100% Protection Against Ebola Virus Infection in Mice

scientific article published on 20 January 2018

Intranasal immunization with an adenovirus vaccine protects guinea pigs from Ebola virus transmission by infected animals

scientific article published on 14 January 2015

Marburg and Ravn Virus Infections Do Not Cause Observable Disease in Ferrets

scholarly article by Gary Wong et al published 22 November 2018 in Journal of Infectious Diseases

Modeling Ebola Virus Transmission Using Ferrets

article

Modelling the effect of early detection of Ebola

scientific article published on 19 January 2015

Molecular characterization of the monoclonal antibodies composing ZMAb: a protective cocktail against Ebola virus

scientific article

Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus

scientific article published on December 2016

Monoclonal antibodies combined with adenovirus-vectored interferon significantly extend the treatment window in Ebola virus-infected guinea pigs

scientific article

More Challenges From Ebola: Infection of the Central Nervous System

scientific article

Mucosal immunization of cynomolgus macaques with the VSVDeltaG/ZEBOVGP vaccine stimulates strong ebola GP-specific immune responses

scientific article

Nanozyme-strip for rapid local diagnosis of Ebola

scientific article published on 11 May 2015

Naturally-occurring single mutations in Ebola observably impact infectivity

scholarly article by Gary Wong et al published 17 October 2018 in Journal of Virology

Noncovalent SUMO-interaction motifs in HIV integrase play important roles in SUMOylation, cofactor binding, and virus replication

article

Optimization of Prime-Boost Vaccination Strategies Against Mouse-Adapted Ebolavirus in a Short-Term Protection Study

scientific article published on 2 June 2015

Pathogenicity Comparison Between the Kikwit and Makona Ebola Virus Variants in Rhesus Macaques

scientific article published on 19 September 2016

Peste des Petits Ruminants Virus-Like Particles Induce a Potent Humoral and Cellular Immune Response in Goats

scientific article published on 05 October 2019

Post-exposure immunotherapy for two ebolaviruses and Marburg virus in nonhuman primates

scientific article published in Nature Communications

Post-exposure therapy of filovirus infections

scientific article

Postexposure Protective Efficacy of T-705 (Favipiravir) Against Sudan Virus Infection in Guinea Pigs

scholarly article by Md N Rahim et al published 22 November 2018 in Journal of Infectious Diseases

Potent neutralizing monoclonal antibodies against Ebola virus infection

scientific article published on 16 May 2016

Potent neutralizing monoclonal antibodies against Ebola virus isolated from vaccinated donors

scientific article published on 01 January 2020

Production and characterization of monoclonal antibodies against different epitopes of Ebola virus antigens.

scientific article published on 19 March 2007

Progression of Ebola Therapeutics During the 2014-2015 Outbreak

scientific article published on 13 January 2016

Prophylactic Efficacy of Quercetin 3-β-O-d-Glucoside against Ebola Virus Infection

scientific article published on 13 June 2016

Protective Efficacy and Long-Term Immunogenicity in Cynomolgus Macaques by Ebola Virus Glycoprotein Synthetic DNA Vaccines

scientific article published on 01 January 2019

Purification and characterization of monoclonal IgG antibodies recognizing Ebola virus glycoprotein

scientific article published on 31 July 2018

Retrospective studies: excellent tools to complement surveillance

scientific article published on 14 November 2013

Reversion of advanced Ebola virus disease in nonhuman primates with ZMapp

scientific article

Small Animal Models for Evaluating Filovirus Countermeasures

scientific article published on 19 February 2018

Spread of ZIKV and YFV to China: Potential Implications

scientific article

Structures of protective antibodies reveal sites of vulnerability on Ebola virus

scientific article

Successful treatment of Marburg virus with orally administrated T-705 (Favipiravir) in a mouse model

scientific article published on 21 January 2018

Successful treatment of ebola virus-infected cynomolgus macaques with monoclonal antibodies

scientific article published on June 2012

Sustained protection against Ebola virus infection following treatment of infected nonhuman primates with ZMAb

scientific article

Synergistic drug combination effectively blocks Ebola virus infection

scientific article

Systematic Analysis of Monoclonal Antibodies against Ebola Virus GP Defines Features that Contribute to Protection

Tangeretin, an extract from Citrus peels, blocks cellular entry of arenaviruses that cause viral hemorrhagic fever

scientific article published on 16 October 2018

Testing Experimental Therapies in a Guinea Pig Model for Hemorrhagic Fever

scientific article published on January 2018

The Cytokine Response Profile of Ebola Virus Disease in a Large Cohort of Rhesus Macaques Treated With Monoclonal Antibodies

The Makona Variant of Ebola Virus Is Highly Lethal to Immunocompromised Mice and Immunocompetent Ferrets

scholarly article by Gary Wong et al published 22 November 2018 in Journal of Infectious Diseases

The Roles of Ebola Virus Soluble Glycoprotein in Replication, Pathogenesis, and Countermeasure Development

scientific article published on 31 October 2019

The Tetherin Antagonism of the Ebola Virus Glycoprotein Requires an Intact Receptor-Binding Domain and Can Be Blocked by GP1-Specific Antibodies

scientific article published on 05 October 2016

The emergence of antibody therapies for Ebola

scientific article

The multiple roles of sGP in Ebola pathogenesis

scientific article

Treatment with hyperimmune equine immunoglobulin or immunoglobulin fragments completely protects rodents from Ebola virus infection

scientific article published on 12 April 2016

Two-mAb cocktail protects macaques against the Makona variant of Ebola virus

scientific article

Ultrasensitive Ebola Virus Detection Based on Electroluminescent Nanospheres and Immunomagnetic Separation

scientific article

VSVΔG/EBOV GP-induced innate protection enhances natural killer cell activity to increase survival in a lethal mouse adapted Ebola virus infection

scientific article published on February 2015

Virus inoculation and treatment regimens for evaluating anti-filovirus monoclonal antibody efficacy in vivo

scientific article published on 01 March 2019

mAbs and Ad-vectored IFN-α therapy rescue Ebola-infected nonhuman primates when administered after the detection of viremia and symptoms

scientific article published on October 2013

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