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List of works by Darwyn Kobasa

A (H1N1) pdm09 HA D222 variants associated with severity and mortality in patients during a second wave in Mexico

scientific article

Aberrant innate immune response in lethal infection of macaques with the 1918 influenza virus

scientific article

Amino Acids Responsible for the Absolute Sialidase Activity of the Influenza A Virus Neuraminidase: Relationship to Growth in the Duck Intestine ⬇️

scientific article published on December 1, 2001

Amino acid residues contributing to the substrate specificity of the influenza A virus neuraminidase

scientific article

Assessment of the efficacy of commercially available and candidate vaccines against a pandemic H1N1 2009 virus.

scientific article

Avian influenza viruses that cause highly virulent infections in humans exhibit distinct replicative properties in contrast to human H1N1 viruses.

scientific article

Balanced hemagglutinin and neuraminidase activities are critical for efficient replication of influenza A virus

scientific article

Cellular immune response in the presence of protective antibody levels correlates with protection against 1918 influenza in ferrets ⬇️

scientific article published on 04 January 2011

Changes in H3 influenza A virus receptor specificity during replication in humans

scientific article

Characterization of Mengo virus neutralization epitopes ⬇️

scientific article published on March 1, 1991

Characterization of Mengo virus neutralization epitopes. II. Infection of mice with an attenuated virus

scientific article published in December 1995

Characterization of a trypsin-dependent avian influenza H5N1-pseudotyped HIV vector system for high throughput screening of inhibitory molecules

scientific article published on 06 March 2008

Co-administration of certain DNA vaccine combinations expressing different H5N1 influenza virus antigens can be beneficial or detrimental to immune protection

scientific article

Comprehending a Killer: The Akt/mTOR Signaling Pathways Are Temporally High-Jacked by the Highly Pathogenic 1918 Influenza Virus.

scientific article

DNA vaccination protects mice against Zika virus-induced damage to the testes

scientific article

Delivering Prolonged Intensive Care to a Non-human Primate: A High Fidelity Animal Model of Critical Illness

scientific article

Detection of airborne severe acute respiratory syndrome (SARS) coronavirus and environmental contamination in SARS outbreak units

scientific article published on 18 March 2005

Development and Characterization of a Guinea Pig-Adapted Sudan Virus

scientific article

Development and Characterization of a Sin Nombre Virus Transmission Model in Peromyscus maniculatus

scholarly article by Bryce M Warner et al published 21 February 2019 in Viruses

Development of neutralizing monoclonal antibodies against the pandemic H1N1 virus (2009) using plasmid DNA immunogen.

scientific article

Ebola viral load at diagnosis associates with patient outcome and outbreak evolution

scientific article

Ebola virus VP40 late domains are not essential for viral replication in cell culture

scientific article

Ebola virus requires phosphatidylinositol (3,5) bisphosphate production for efficient viral entry

scientific article published on 11 October 2017

Emerging influenza viruses: past and present.

scientific article

Enhanced neurovirulence of borna disease virus variants associated with nucleotide changes in the glycoprotein and L polymerase genes

scientific article

Enhanced virulence of influenza A viruses with the haemagglutinin of the 1918 pandemic virus.

scientific article

Evaluation of a neonatal rat model for prediction of mumps virus neurovirulence in humans

scientific article published on June 2000

Evaluation of conserved and variable influenza antigens for immunization against different isolates of H5N1 viruses.

scientific article

Generation and Characterization of Anti-Filovirus Nucleoprotein Monoclonal Antibodies

scholarly article by Md Niaz Rahim et al published 14 March 2019 in Viruses

Hemagglutinin-Neuraminidase Balance Influences the Virulence Phenotype of a Recombinant H5N3 Influenza A Virus Possessing a Polybasic HA0 Cleavage Site

scientific article

Heterosubtypic protection against pathogenic human and avian influenza viruses via in vivo electroporation of synthetic consensus DNA antigens

scientific article

Highly Pathogenic H5N1 and Novel H7N9 Influenza A Viruses Induce More Profound Proteomic Host Responses than Seasonal and Pandemic H1N1 Strains.

scientific article

Human macrophage C-type lectin specific for galactose and N-acetylgalactosamine promotes filovirus entry

scientific article published on March 2004

Human polyclonal antibodies produced in transchromosomal cattle prevent lethal Zika virus infection and testicular atrophy in mice

scientific article published on 8 September 2017

Identification of Mengo virus T helper cell epitopes

scientific article published on November 1994

Inhibition of multiple subtypes of influenza A virus in cell cultures with morpholino oligomers

scientific article

Intranasal administration of alpha interferon reduces seasonal influenza A virus morbidity in ferrets

scientific article

Intranasal antibody gene transfer in mice and ferrets elicits broad protection against pandemic influenza

scientific article

Lethal influenza virus infection in macaques is associated with early dysregulation of inflammatory related genes

scientific article

Limited Effects of Type I Interferons on Kyasanur Forest Disease Virus in Cell Culture

scientific article

Molecular determinants of Ebola virus virulence in mice

scientific article published in July 2006

Naturally-occurring single mutations in Ebola observably impact infectivity

scholarly article by Gary Wong et al published 17 October 2018 in Journal of Virology

Neuraminidase hemadsorption activity, conserved in avian influenza A viruses, does not influence viral replication in ducks ⬇️

scientific article published on September 1, 1997

Novel avian influenza H7N3 strain outbreak, British Columbia

scientific article

Pandemic swine-origin H1N1 influenza A virus isolates show heterogeneous virulence in macaques

scientific article

Partial protection against H5N1 influenza in mice with a single dose of a chimpanzee adenovirus vector expressing nucleoprotein

scientific article

Pathobiological Characterization of a Novel Reassortant Highly Pathogenic H5N1 Virus Isolated in British Columbia, Canada, 2015.

scientific article published on 18 March 2016

Pathogenicity of Nipah henipavirus Bangladesh in a swine host

article published in 2019

Post-exposure treatment with whole inactivated H5N1 avian influenza virus protects against lethal homologous virus infection in mice

scientific article published on 12 July 2016

Potent vesicular stomatitis virus-based avian influenza vaccines provide long-term sterilizing immunity against heterologous challenge.

scientific article

Prior Infection of Chickens with H1N1 or H1N2 Avian Influenza Elicits Partial Heterologous Protection against Highly Pathogenic H5N1 ⬇️

scientific article published on December 11, 2012

Prior infection of chickens with H1N1 avian influenza virus elicits heterologous protection against highly pathogenic H5N2 ⬇️

scientific article published on October 19, 2012

Proteolytic activation of the 1918 influenza virus hemagglutinin

scientific article published on 21 January 2009

Quantitative proteomic analyses of influenza virus-infected cultured human lung cells

scientific article

Randomized controlled ferret study to assess the direct impact of 2008-09 trivalent inactivated influenza vaccine on A(H1N1)pdm09 disease risk

scientific article

Rapid one-step construction of a Middle East Respiratory Syndrome (MERS-CoV) infectious clone system by homologous recombination

scientific article published on 23 July 2016

Recently emerged swine influenza A virus (H2N3) causes severe pneumonia in Cynomolgus macaques

scientific article published in 2012

Reduction of Neuraminidase Activity Exacerbates Disease in 2009 Pandemic Influenza Virus-Infected Mice

scientific article

The 2009 pandemic H1N1 D222G hemagglutinin mutation alters receptor specificity and increases virulence in mice but not in ferrets

scientific article

The Disinfection Characteristics of Ebola Virus Outbreak Variants

scientific article (publication date: 2 December 2016)

The Makona Variant of Ebola Virus Is Highly Lethal to Immunocompromised Mice and Immunocompetent Ferrets

scholarly article by Gary Wong et al published 22 November 2018 in Journal of Infectious Diseases

The interaction between the Nipah virus nucleocapsid protein and phosphoprotein regulates virus replication

scientific article published in Scientific Reports

Vectored expression of the broadly neutralizing antibody FI6 in mouse airway provides partial protection against a new avian influenza A virus, H7N9.

scientific article

Vesicular stomatitis virus vectors expressing avian influenza H5 HA induce cross-neutralizing antibodies and long-term protection.

scientific article

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