List of works by Kimberly A Dowd

A CRISPR screen defines a signal peptide processing pathway required by flaviviruses

scientific article

A VSV-based Zika virus vaccine protects mice from lethal challenge

scientific article published on 23 July 2018

A Virus-Like Particle Vaccine Elicits Broad Neutralizing Antibody Responses in Humans to All Chikungunya Virus Genotypes

scientific article published on 21 September 2016

A dynamic landscape for antibody binding modulates antibody-mediated neutralization of West Nile virus ⬇️

scientific article

A novel approach for the rapid mutagenesis and directed evolution of the structural genes of west nile virus

scientific article

A single mutation in the envelope protein modulates flavivirus antigenicity, stability, and pathogenesis

scientific article (publication date: 16 February 2017)

Acceleration of hepatitis C virus envelope evolution in humans is consistent with progressive humoral immune selection during the transition from acute to chronic infection

scientific article published on 3 March 2010

Antibody-mediated neutralization of flaviviruses: a reductionist view

scientific article

B cell response and mechanisms of antibody protection to West Nile virus

scientific article published on 03 March 2014

Broadly Neutralizing Activity of Zika Virus-Immune Sera Identifies a Single Viral Serotype ⬇️

scientific article

CD4+ T-Cell-Dependent Reduction in Hepatitis C Virus-Specific Neutralizing Antibody Responses After Coinfection With Human Immunodeficiency Virus

scientific article

Combined effects of the structural heterogeneity and dynamics of flaviviruses on antibody recognition

scientific article

Complex phenotypes in mosquitoes and mice associated with neutralization escape of a Dengue virus type 1 monoclonal antibody

scientific article published on 9 March 2012

Context-Dependent Cleavage of the Capsid Protein by the West Nile Virus Protease Modulates the Efficiency of Virus Assembly

scientific article published on 10 June 2015

Development of a highly protective combination monoclonal antibody therapy against Chikungunya virus

scientific article (publication date: 2013)

Engineered Dengue Virus Domain III Proteins Elicit Cross-Neutralizing Antibody Responses in Mice

article

Enhancing dengue virus maturation using a stable furin over-expressing cell line

scientific article published on 12 July 2016

Genotypic Differences in Dengue Virus Neutralization Are Explained by a Single Amino Acid Mutation That Modulates Virus Breathing

scientific article

Hepatitis C virus infection of neuroepithelioma cell lines

scientific article published on 9 June 2010

High-programmed death-1 levels on hepatitis C virus-specific T cells during acute infection are associated with viral persistence and require preservation of cognate antigen during chronic infection

scientific article

Impact of viral attachment factor expression on antibody-mediated neutralization of flaviviruses

scientific article published on 10 January 2013

Maternal Neutralizing Antibody and Transmission of Hepatitis C Virus to Infants

scientific article (publication date: December 2008)

Mechanism and significance of cell type-dependent neutralization of flaviviruses

scientific article

Modified mRNA Vaccines Protect against Zika Virus Infection

scientific article published on 16 February 2017

Modified mRNA Vaccines Protect against Zika Virus Infection

scientific article published on March 2017

Netrin binds discrete subdomains of DCC and UNC5 and mediates interactions between DCC and heparin

scientific article (publication date: 29 August 2003)

Poorly neutralizing cross-reactive antibodies against the fusion loop of West Nile virus envelope protein protect in vivo via Fcgamma receptor and complement-dependent effector mechanisms

scientific article published on 14 September 2011

Potent dengue virus neutralization by a therapeutic antibody with low monovalent affinity requires bivalent engagement

scientific article

Pseudo-infectious reporter virus particles for measuring antibody-mediated neutralization and enhancement of dengue virus infection

scientific article published on January 2014

Rapid development of a DNA vaccine for Zika virus

scientific article

Safety and tolerability of chikungunya virus-like particle vaccine in healthy adults: a phase 1 dose-escalation trial

scientific article published on 14 August 2014

Safety, tolerability, and immunogenicity of two Zika virus DNA vaccine candidates in healthy adults: randomised, open-label, phase 1 clinical trials

scientific article published on 4 December 2017

Selection pressure from neutralizing antibodies drives sequence evolution during acute infection with hepatitis C virus

scientific article

Shake, rattle, and roll: Impact of the dynamics of flavivirus particles on their interactions with the host

scientific article

Spontaneous control of primary hepatitis C virus infection and immunity against persistent reinfection

scientific article published on 24 September 2009

Structural Basis of Differential Neutralization of DENV-1 Genotypes by an Antibody that Recognizes a Cryptic Epitope

scientific article

Structural Basis of Zika Virus-Specific Antibody Protection

scientific article published on 26 July 2016

Structure and function analysis of therapeutic monoclonal antibodies against dengue virus type 2.

scientific article

The Fc region of an antibody impacts the neutralization of West Nile viruses in different maturation states

scientific article published on 09 October 2013

The Many Faces of a Dynamic Virion: Implications of Viral Breathing on Flavivirus Biology and Immunogenicity

scientific article published on 01 September 2018

The infectivity of prM-containing partially mature West Nile virus does not require the activity of cellular furin-like proteases

scientific article published on 31 August 2011

The type-specific neutralizing antibody response elicited by a dengue vaccine candidate is focused on two amino acids of the envelope protein

scientific article

Vaccine Mediated Protection Against Zika Virus-Induced Congenital Disease

scientific article published on July 2017

Zika Virus Is Not Uniquely Stable at Physiological Temperatures Compared to Other Flaviviruses

scientific article

Zika virus protection by a single low-dose nucleoside-modified mRNA vaccination

scientific article

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