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List of works by Michael J. Keating

462Impact of Pre-transplant LVAD Therapy on Survival and Infectious Complications in Heart Transplant Recipients.

scientific article

A high-density SNP genome-wide linkage search of 206 families identifies susceptibility loci for chronic lymphocytic leukemia

scientific article published on 8 August 2007

A phase 2 study of idelalisib plus rituximab in treatment-naïve older patients with chronic lymphocytic leukemia

scientific article published on 15 October 2015

A phase 2 study of yttrium-90 ibritumomab tiuxetan (Zevalin) in patients with chronic lymphocytic leukemia

scientific article

A phase I study of fludarabine, cytarabine, and oxaliplatin therapy in patients with relapsed or refractory acute myeloid leukemia

scientific article

A phase I-II trial of fludarabine, bendamustine and rituximab (FBR) in previously treated patients with CLL.

scientific article

A phase II study of the combination of rituximab and granulocyte macrophage colony stimulating factor as treatment of patients with chronic lymphocytic leukemia

scientific article

A phase II trial of eltrombopag for patients with chronic lymphocytic leukaemia (CLL) and thrombocytopenia

scientific article published on 08 November 2018

A randomized trial of liposomal daunorubicin and cytarabine versus liposomal daunorubicin and topotecan with or without thalidomide as initial therapy for patients with poor prognosis acute myelogenous leukemia or myelodysplastic syndrome

scientific article published in March 2003

A retrospective comparison of three sequential groups of patients with Recurrent/Refractory chronic lymphocytic leukemia treated with fludarabine-based regimens

scientific article

A systematic approach to diagnosis of mature T-cell leukemias reveals heterogeneity among WHO categories

scientific article published on 25 March 2004

A two-gene signature, SKI and SLAMF1, predicts time-to-treatment in previously untreated patients with chronic lymphocytic leukemia

scientific article

Aberrant LPL Expression, Driven by STAT3, Mediates Free Fatty Acid Metabolism in CLL Cells

scientific article published on 2 March 2015

Activation of the B-cell receptor successively activates NF-κB and STAT3 in chronic lymphocytic leukemia cells

scientific article

Activity of alemtuzumab in patients with CD52-positive acute leukemia

scientific article published on 01 June 2006

Adult acute megakaryocytic leukemia: an analysis of 37 patients treated at M.D. Anderson Cancer Center

scientific article published on 25 August 2005

Alemtuzumab as treatment for residual disease after chemotherapy in patients with chronic lymphocytic leukemia

scientific article published in December 2003

Alemtuzumab by continuous intravenous infusion followed by subcutaneous injection plus rituximab in the treatment of patients with chronic lymphocytic leukemia recurrence

scientific article published on May 2010

Alemtuzumab: validation of a sensitive and simple enzyme-linked immunosorbent assay

scientific article published in December 2004

Allogeneic blood or marrow transplantation for chronic lymphocytic leukaemia: timing of transplantation and potential effect of fludarabine on acute graft-versus-host disease

scientific article published on 01 May 1997

Allogeneic haematopoietic transplantation for Richter's syndrome

scientific article published on 01 September 2000

Alterations of mitochondrial biogenesis in chronic lymphocytic leukemia cells with loss of p53.

scientific article published on 17 September 2016

Alvimopan in the setting of colorectal resection with an ostomy: To use or not to use?

scientific article published on 7 December 2016

Amifostine does not reduce the toxicity of the fludarabine and cyclophosphamide regimen in patients with chronic lymphocytic leukemia

scientific article

Anaplastic large cell lymphoma with involvement of the pancreas presenting as panniculitis in a patient with a history of acute myeloid leukemia--case report and review of the literature.

scientific article published on December 2006

Array CGH analysis of chronic lymphocytic leukemia reveals frequent cryptic monoallelic and biallelic deletions of chromosome 22q11 that include the PRAME gene.

scientific article

Array Comparative Genomic Hybridization Analysis Identifies Recurrent Gain of Chromosome 2p25.3 Involving the ACP1 and MYCN Genes in Chronic Lymphocytic Leukemia ⬇️

scientific article published on May 5, 2011

Assessment of chronic lymphocytic leukemia and small lymphocytic lymphoma by absolute lymphocyte counts in 2,126 patients: 20 years of experience at the University of Texas M.D. Anderson Cancer Center

scientific article published in October 2007

Association of a microRNA/TP53 feedback circuitry with pathogenesis and outcome of B-cell chronic lymphocytic leukemia

scientific article published on January 2011

Association of gene mutations with time-to-first treatment in 384 treatment-naive chronic lymphocytic leukaemia patients

scientific article published on 26 June 2019

At High Levels, Constitutively Activated STAT3 Induces Apoptosis of Chronic Lymphocytic Leukemia Cells

scientific article published on 13 April 2016

Atypical chronic lymphocytic leukemia with polyglandular autoimmune endocrinopathy type II: a complex profile

scientific article

Aurora-A kinase nuclear expression in chronic lymphocytic leukemia.

scientific article

Autoimmune cytopenias in patients with chronic lymphocytic leukemia treated with ibrutinib

scientific article published on 24 March 2016

Autologous and allogeneic bone marrow transplantation for chronic lymphocytic leukemia: preliminary results

scientific article published on 01 April 1994

Azacitidine in fludarabine-refractory chronic lymphocytic leukemia: a phase II study

scientific article

B cell receptor signaling regulates metabolism in Chronic Lymphocytic Leukemia

scientific article

B-Lymphoblastic Leukemia in Patients With Chronic Lymphocytic Leukemia: A Report of Four Cases

scientific article

B-cell antigen receptor signaling enhances chronic lymphocytic leukemia cell migration and survival: specific targeting with a novel spleen tyrosine kinase inhibitor, R406.

scientific article published on 02 June 2009

Biological and clinical heterogeneity of B-cell chronic lymphocytic leukemia

scientific article

Biological and metabolic effects of IACS-010759, an OxPhos inhibitor, on chronic lymphocytic leukemia cells.

scientific article

Biological validation of differentially expressed genes in chronic lymphocytic leukemia identified by applying multiple statistical methods to oligonucleotide microarrays

scientific article published on August 2005

Biology and treatment of chronic lymphocytic leukemia

scientific article published on January 2003

Blood collection methods affect cellular protein integrity: implications for clinical trial biomarkers and ZAP-70 in CLL.

scientific article published on August 2014

Bone marrow cyclooxygenase-2 levels are elevated in chronic-phase chronic myeloid leukaemia and are associated with reduced survival

scientific article published in October 2002

CCL3 (MIP-1α) plasma levels and the risk for disease progression in chronic lymphocytic leukemia ⬇️

scientific article published on November 29, 2010

CCL3 and CCL4 are biomarkers for B cell receptor pathway activation and prognostic serum markers in diffuse large B cell lymphoma

scientific article

CD28 costimulation improves expansion and persistence of chimeric antigen receptor-modified T cells in lymphoma patients

scientific article

CD4(-)/CD8(-) variant of T-cell large granular lymphocytic leukemia or hepatosplenic T-cell lymphoma: a clinicopathologic dilemma

scientific article published on 22 June 2013

Calreticulin as a novel B-cell receptor antigen in chronic lymphocytic leukemia

scientific article published on 27 July 2017

Cardiac toxicity of alemtuzumab in patients with mycosis fungoides/Sézary syndrome

scientific article published on 8 April 2004

Carfilzomib Triggers Cell Death in Chronic Lymphocytic Leukemia by Inducing Proapoptotic and Endoplasmic Reticulum Stress Responses

scientific article published on 29 March 2016

Caspase-8 dependent histone acetylation by a novel proteasome inhibitor, NPI-0052: a mechanism for synergy in leukemia cells

scientific article published on 30 January 2009

Cell death of bioenergetically compromised and transcriptionally challenged CLL lymphocytes by chlorinated ATP

scientific article published on 17 February 2005

Characteristics associated with important clinical end points in patients with chronic lymphocytic leukemia at initial treatment

scientific article published on 17 February 2009

Characterization of 4 mantle cell lymphoma cell lines

scientific article (publication date: April 2003)

Chemoimmunotherapy may overcome the adverse prognostic significance of 11q deletion in previously untreated patients with chronic lymphocytic leukemia

scientific article

Chemoimmunotherapy of chronic lymphocytic leukemia

scientific article published on September 2007

Chemoimmunotherapy of chronic lymphocytic leukemia

scientific article published on 6 July 2010

Chemoimmunotherapy with a modified hyper-CVAD and rituximab regimen improves outcome in de novo Philadelphia chromosome-negative precursor B-lineage acute lymphoblastic leukemia

scientific article

Chemoimmunotherapy with fludarabine, cyclophosphamide, and rituximab for relapsed and refractory chronic lymphocytic leukemia

scientific article

Chemoimmunotherapy with hyper-CVAD plus rituximab for the treatment of adult Burkitt and Burkitt-type lymphoma or acute lymphoblastic leukemia

scientific article

Chlorinated adenosine analogue induces AMPK and autophagy in chronic lymphocytic leukaemia cells during therapy

scientific article published on 24 July 2017

Chronic lymphocytic leukaemia CD20 expression is dependent on the genetic subtype: a study of quantitative flow cytometry and fluorescent in-situ hybridization in 510 patients

scientific article

Chronic lymphocytic leukemia With t(2;14)(p16;q32) involves the BCL11A and IgH genes and is associated with atypical morphologic features and unmutated IgVH genes

scientific article published in May 2009

Chronic lymphocytic leukemia and myeloproliferative neoplasms concurrently diagnosed: clinical and biological characteristics

scientific article published on 24 September 2015

Chronic lymphocytic leukemia presenting in association with aplastic anemia

scientific article

Chronic lymphocytic leukemia with central nervous system involvement: a high-risk disease?

scientific article

Chronic lymphocytic leukemia with t(14;19)(q32;q13) is characterized by atypical morphologic and immunophenotypic features and distinctive genetic features.

scientific article

Circulating CD20 and CD52 in patients with non-Hodgkin's lymphoma or Hodgkin's disease

scientific article published on 01 December 2003

Circulating CD52 and CD20 levels at end of treatment predict for progression and survival in patients with chronic lymphocytic leukaemia treated with fludarabine, cyclophosphamide and rituximab (FCR).

scientific article published on 6 November 2009

Circulating Ki-67 index in plasma as a biomarker and prognostic indicator in chronic lymphocytic leukemia

scientific article

Circulating heat shock protein 70 and progression in patients with chronic myeloid leukemia

scientific article

Clinical and molecular characteristics of XPO1 mutations in patients with chronic lymphocytic leukemia

scientific article published on 28 July 2016

Clinical characteristics, response to therapy, and survival of African American patients diagnosed with chronic lymphocytic leukemia: joint experience of the MD Anderson Cancer Center and Duke University Medical Center

scientific article

Clinical effects of alemtuzumab (Campath-1H) in B-cell chronic lymphocytic leukemia

scientific article

Clinical implications of cancer gene mutations in patients with chronic lymphocytic leukemia treated with lenalidomide

scientific article

Clinical outcomes and prognostic factors in patients with Richter's syndrome treated with chemotherapy or chemoimmunotherapy with or without stem-cell transplantation

scientific article

Clinical relevance of soluble HLA-I and beta2-microglobulin levels in non-Hodgkin's lymphoma and Hodgkin's disease

scientific article published on 20 March 2006

Clofarabine, a novel nucleoside analog, is active in pediatric patients with advanced leukemia ⬇️

scientific article published on October 9, 2003

Clonal evolution in patients with chronic lymphocytic leukaemia developing resistance to BTK inhibition

scientific article published on 20 May 2016

Combination of Pim kinase inhibitors and Bcl-2 antagonists in chronic lymphocytic leukemia cells

scientific article published on 19 June 2015

Combining Anti-Mir-155 with Chemotherapy for the Treatment of Lung Cancers

scientific article published on 30 November 2016

Comparison of Acalabrutinib, A Selective Bruton Tyrosine Kinase Inhibitor, with Ibrutinib in Chronic Lymphocytic Leukemia Cells

scientific article

Complete cytogenetic and molecular responses to interferon-alpha-based therapy for chronic myelogenous leukemia are associated with excellent long-term prognosis

scientific article

Complex karyotype is a stronger predictor than del(17p) for an inferior outcome in relapsed or refractory chronic lymphocytic leukemia patients treated with ibrutinib-based regimens

scientific article published on 20 July 2015

Concomitant ventral phalloplasty during penile implant surgery: a novel procedure that optimizes patient satisfaction and their perception of phallic length after penile implant surgery

scientific article published in September 2007

Consolidation treatment with lenalidomide following front-line or salvage chemoimmunotherapy in chronic lymphocytic leukemia

scientific article published on 10 August 2017

Constitutive Phosphorylation of STAT3 by the CK2-BLNK-CD5 Complex

scientific article published on 27 January 2017

Correction: Novel Role of NOX in Supporting Aerobic Glycolysis in Cancer Cells with Mitochondrial Dysfunction and as a Potential Target for Cancer Therapy

scientific article published on 11 December 2017

Correlation between FDG/PET, histology, characteristics, and survival in 332 patients with chronic lymphoid leukemia

scientific article

Cost-effectiveness of adding rituximab to fludarabine and cyclophosphamide for the treatment of previously untreated chronic lymphocytic leukemia ⬇️

scientific article published on September 19, 2011

Critical appraisal of the role of rituximab in the treatment of patients with previously untreated or treated chronic lymphocytic leukemia (CLL) ⬇️

scientific article published on June 21, 2010

Cross-talk between chronic lymphocytic leukemia cells and bone marrow endothelial cells: role of signal transducer and activator of transcription 3 ⬇️

scientific article published on July 5, 2011

Current guidelines in defining therapeutic strategies

scientific article published in August 2004

Customized oligonucleotide array-based comparative genomic hybridization as a clinical assay for genomic profiling of chronic lymphocytic leukemia

scientific article

Cyclophosphamide, fludarabine, alemtuzumab, and rituximab as salvage therapy for heavily pretreated patients with chronic lymphocytic leukemia ⬇️

scientific article published on June 13, 2011

DNA repair initiation induces expression of ribonucleotide reductase in human chronic lymphocytic leukemia cells ⬇️

scientific article published on July 29, 2013

De novo deletion 17p13.1 chronic lymphocytic leukemia shows significant clinical heterogeneity: the M. D. Anderson and Mayo Clinic experience

scientific article published on 04 May 2009

Del(20q) in patients with chronic lymphocytic leukemia: a therapy-related abnormality involving lymphoid or myeloid cells

scientific article published on 8 May 2015

Describing a Transcription Factor Dependent Regulation of the MicroRNA Transcriptome

scientific article published on 15 June 2016

Detection of Richter's transformation of chronic lymphocytic leukemia by PET/CT.

scientific article published in August 2006

Detection of nucleophosmin gene mutations in plasma from patients with acute myeloid leukemia: clinical significance and implications

scientific article published in January 2009

Diverse marrow stromal cells protect CLL cells from spontaneous and drug-induced apoptosis: development of a reliable and reproducible system to assess stromal cell adhesion-mediated drug resistance

scientific article published on 17 September 2009

Dynamic changes in CCL3 and CCL4 plasma concentrations in patients with chronic lymphocytic leukaemia managed with observation.

scientific article published on 21 October 2016

Dynamic changes of the normal B lymphocyte repertoire in CLL in response to ibrutinib or FCR chemo-immunotherapy

scientific article published on 15 January 2018

Dynamic model for predicting death within 12 months in patients with primary or post-polycythemia vera/essential thrombocythemia myelofibrosis

scientific article published on 28 September 2009

Early results of a chemoimmunotherapy regimen of fludarabine, cyclophosphamide, and rituximab as initial therapy for chronic lymphocytic leukemia

scientific article

Economic Burden of Chronic Lymphocytic Leukemia in the Era of Oral Targeted Therapies in the United States

scientific article published on 21 November 2016

Effective Elimination of Cancer Stem Cells By a Novel Drug Combination Strategy ⬇️

scientific article published on January 1, 2013

Effective elimination of fludarabine-resistant CLL cells by PEITC through a redox-mediated mechanism

scientific article published on 23 June 2008

Effects of the proteasome inhibitor, bortezomib, on apoptosis in isolated lymphocytes obtained from patients with chronic lymphocytic leukemia.

scientific article published in October 2003

Efficacy and predictors of response of lenalidomide and rituximab in patients with treatment-naive and relapsed CLL

scientific article published on 01 May 2019

Emerging information on the use of rituximab in chronic lymphocytic leukemia

scientific article

Engraftment of allogeneic hematopoietic progenitor cells with purine analog-containing chemotherapy: harnessing graft-versus-leukemia without myeloablative therapy

scientific article published on 01 June 1997

Enzymatic activity of circulating proteasomes correlates with clinical behavior in patients with chronic lymphocytic leukemia

scientific article published in March 2008

Epstein-Barr Virus MicroRNAs are Expressed in Patients with Chronic Lymphocytic Leukemia and Correlate with Overall Survival

scientific article

Epstein-Barr virus in patients with chronic lymphocytic leukemia: a pilot study

scientific article published in May 2006

Epstein-Barr virus latent membrane protein 1 mRNA is expressed in a significant proportion of patients with chronic lymphocytic leukemia

scientific article

Epstein-Barr virus-positive B-cell lymphoproliferative disorders arising in immunodeficient patients previously treated with fludarabine for low-grade B-cell neoplasms

scientific article published in May 2002

Eradication of bone marrow minimal residual disease may prompt early treatment discontinuation in CLL.

scientific article

Eradication of minimal residual disease in hairy cell leukemia

scientific article

Establishment of baseline toxicity expectations with standard frontline chemotherapy in acute myelogenous leukemia

scientific article published on 02 August 2007

Evaluation of bendamustine in combination with fludarabine in primary chronic lymphocytic leukemia cells

scientific article

Experience with alemtuzumab plus rituximab in patients with relapsed and refractory lymphoid malignancies

scientific article published on 09 January 2003

Experience with rituximab immunotherapy as an early intervention in patients with Rai stage 0 to II chronic lymphocytic leukemia

scientific article

Expression of executioner procaspases and their activation by a procaspase-activating compound in chronic lymphocytic leukemia cells

scientific article

Externally validated predictive clinical model for untreated del(17p13.1) chronic lymphocytic leukemia patients

scientific article published on 22 July 2015

FCR and bevacizumab treatment in patients with relapsed chronic lymphocytic leukemia

scientific article

Factors Associated with Neurologists' Provision of MS Patient Care

scientific article

Factors influencing interest in providing MS patient care among physiatry residents

scientific article published in January 2014

Factors influencing professional life satisfaction among neurologists

scientific article

Factors influencing the desire to provide MS patient care in clinical practice among physiatrists

scientific article

Fine-needle aspiration biopsy findings in patients with small lymphocytic lymphoma transformed to hodgkin lymphoma

scientific article published in October 2007

Fludarabine and mitoxantrone for patients with chronic lymphocytic leukemia

scientific article published in June 2004

Fludarabine increases oxaliplatin cytotoxicity in normal and chronic lymphocytic leukemia lymphocytes by suppressing interstrand DNA crosslink removal

scientific article published on 5 September 2006

Fludarabine, cyclophosphamide and rituximab plus granulocyte macrophage colony-stimulating factor as frontline treatment for patients with chronic lymphocytic leukemia ⬇️

scientific article published on July 29, 2013

Fludarabine, cyclophosphamide, and multiple-dose rituximab as frontline therapy for chronic lymphocytic leukemia

scientific article

Fludarabine, cyclophosphamide, and rituximab chemoimmunotherapy is highly effective treatment for relapsed patients with CLL.

scientific article

Fludarabine, cyclophosphamide, and rituximab treatment achieves long-term disease-free survival in IGHV-mutated chronic lymphocytic leukemia

scientific article published on 22 October 2015

Fludarabine, cyclophosphamide, mitoxantrone plus rituximab (FCM-R) in frontline CLL <70 Years

scientific article published on 30 July 2009

Foresight: Scotland Decides

article

Forodesine, an inhibitor of purine nucleoside phosphorylase, induces apoptosis in chronic lymphocytic leukemia cells

scientific article published on 15 June 2006

Forodesine: review of preclinical and clinical data

scientific article

Fractionated cyclophosphamide, vincristine, liposomal daunorubicin, and dexamethasone plus rituximab and granulocyte-macrophage-colony stimulating factor (GM-CSF) alternating with methotrexate and cytarabine plus rituximab and GM-CSF in patients wit

scientific article published in April 2003

Free radical stress in chronic lymphocytic leukemia cells and its role in cellular sensitivity to ROS-generating anticancer agents

scientific article published on 16 January 2003

Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia

scientific article

Frontline chemoimmunotherapy with fludarabine, cyclophosphamide, alemtuzumab, and rituximab for high-risk chronic lymphocytic leukemia ⬇️

scientific article published on July 12, 2011

Functional Differences between IgM and IgD Signaling in Chronic Lymphocytic Leukemia

scientific article published on 17 August 2016

Gemtuzumab, fludarabine, cytarabine, and cyclosporine in patients with newly diagnosed acute myelogenous leukemia or high-risk myelodysplastic syndromes

scientific article published in March 2003

Generation of Functional CLL-Specific Cord Blood CTL Using CD40-Ligated CLL APC ⬇️

scientific article published on December 19, 2012

Genome-wide DNA methylation profiling of chronic lymphocytic leukemia allows identification of epigenetically repressed molecular pathways with clinical impact

scientific article published on 16 August 2010

Genomic variation by whole-genome SNP mapping arrays predicts time-to-event outcome in patients with chronic lymphocytic leukemia: a comparison of CLL and HapMap genotypes

scientific article published on 27 December 2012

Gossypol, a BH3 mimetic, induces apoptosis in chronic lymphocytic leukemia cells

scientific article published on 19 June 2008

Graft-versus-leukaemia effect after non-myeloablative haematopoietic transplantation can overcome the unfavourable expression of ZAP-70 in refractory chronic lymphocytic leukaemia

scientific article published on 01 May 2007

Guidelines for diagnosis, indications for treatment, response assessment and supportive management of chronic lymphocytic leukemia

scientific article published on 14 March 2018

Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines

scientific article

Hematopoietic stem cell transplantation for chronic lymphocytic leukemia

scientific article published on 01 November 1998

High TCL1 levels are a marker of B-cell receptor pathway responsiveness and adverse outcome in chronic lymphocytic leukemia

scientific article published on 21 September 2009

High expression of activation-induced cytidine deaminase (AID) and splice variants is a distinctive feature of poor-prognosis chronic lymphocytic leukemia

scientific article published on 13 February 2003

High fluorescence in situ hybridization percentage of deletion 11q in patients with chronic lymphocytic leukemia is an independent predictor of adverse outcome

scientific article published on 30 March 2015

High serum thymidine kinase 1 level predicts poorer survival in patients with chronic lymphocytic leukemia

scientific article published on September 2010

High-dose caspofungin combination antifungal therapy in patients with hematologic malignancies and hematopoietic stem cell transplantation

scientific article published in February 2007

High-dose chemotherapy for chronic lymphocytic leukemia: Eligibility, timing, and benefit? ⬇️

scientific article published on 01 February 1998

High-level expression of the T-cell chemokines CCL3 and CCL4 by chronic lymphocytic leukemia B cells in nurselike cell cocultures and after BCR stimulation

scientific article published on 12 December 2008

Histone deacetylases mediate the silencing of miR-15a, miR-16, and miR-29b in chronic lymphocytic leukemia ⬇️

scientific article published on November 16, 2011

Hodgkin transformation of chronic lymphocytic leukemia: the M. D. Anderson Cancer Center experience

scientific article published in September 2006

Hyperuricemic syndromes in cancer patients

scientific article

Ibrutinib Therapy Increases T Cell Repertoire Diversity in Patients with Chronic Lymphocytic Leukemia

scientific article published on 11 January 2017

Ibrutinib efficacy and tolerability in patients with relapsed chronic lymphocytic leukemia following allogeneic HCT.

scientific article

Ibrutinib for patients with relapsed or refractory chronic lymphocytic leukaemia with 17p deletion (RESONATE-17): a phase 2, open-label, multicentre study

scientific article published on 13 September 2016

Ibrutinib increases the risk of atrial fibrillation, potentially through inhibition of cardiac PI3K-Akt signaling.

scientific article published in December 2014

Ibrutinib inhibits free fatty acid metabolism in chronic lymphocytic leukemia

scientific article published on 21 February 2018

Idelalisib and bendamustine combination is synergistic and increases DNA damage response in chronic lymphocytic leukemia cells

scientific article published on 07 February 2017

Identification and validation of biomarkers of IgV(H) mutation status in chronic lymphocytic leukemia using microfluidics quantitative real-time polymerase chain reaction technology

scientific article

Imatinib mesylate for Philadelphia chromosome-positive, chronic-phase myeloid leukemia after failure of interferon-alpha: follow-up results.

scientific article

Imatinib mesylate therapy improves survival in patients with newly diagnosed Philadelphia chromosome-positive chronic myelogenous leukemia in the chronic phase: comparison with historic data

scientific article

Immune anaemias in patients with chronic lymphocytic leukaemia treated with fludarabine, cyclophosphamide and rituximab--incidence and predictors

scientific article published in March 2007

Immunohistochemical detection of ZAP70 in chronic lymphocytic leukemia predicts immunoglobulin heavy chain gene mutation status and time to progression

scientific article

Impaired bactericidal but not fungicidal activity of polymorphonuclear neutrophils in patients with chronic lymphocytic leukemia

scientific article published on 20 February 2013

Importance of minimal residual disease in hairy cell leukemia: monoclonal antibodies as a therapeutic strategy

scientific article published on October 2009

In vitro effects of STI 571-containing drug combinations on the growth of Philadelphia-positive chronic myelogenous leukemia cells

scientific article published in May 2002

Increased apoptosis in bone marrow B lymphocytes but not T lymphocytes in myelodysplastic syndrome

scientific article published in May 2003

Increased telomerase activity is associated with shorter survival in patients with chronic phase chronic myeloid leukemia

scientific article published in March 2003

Inhibition of glycolysis in cancer cells: a novel strategy to overcome drug resistance associated with mitochondrial respiratory defect and hypoxia.

scientific article published in January 2005

Inhibition of mitochondrial respiration: a novel strategy to enhance drug-induced apoptosis in human leukemia cells by a reactive oxygen species-mediated mechanism

scientific article

Input subsidies to improve smallholder maize productivity in Malawi: toward an african green revolution

scientific article

Intensive chemotherapy does not benefit most older patients (age 70 years or older) with acute myeloid leukemia

scientific article published on 28 July 2010

Interest in providing multiple sclerosis care and subspecializing in multiple sclerosis among neurology residents

scientific article published on January 2014

Intrinsic oxidative stress in cancer cells: a biochemical basis for therapeutic selectivity ⬇️

scientific article published on November 11, 2003

Is Modern Medical Management Changing Ultimate Patient Outcomes in Inflammatory Bowel Disease?

scientific article published on 15 September 2016

Isoform-selective phosphoinositide 3'-kinase inhibitors inhibit CXCR4 signaling and overcome stromal cell-mediated drug resistance in chronic lymphocytic leukemia: a novel therapeutic approach

scientific article

Isolation of a novel chronic lymphocytic leukemic (CLL) cell line and development of an in vivo mouse model of CLL.

scientific article published on 19 October 2015

K-rasG12V transformation leads to mitochondrial dysfunction and a metabolic switch from oxidative phosphorylation to glycolysis ⬇️

scientific article published on August 30, 2011

Kinetics of CLL cells in tissues and blood during therapy with the BTK inhibitor ibrutinib

scientific article

LDOC1 mRNA is differentially expressed in chronic lymphocytic leukemia and predicts overall survival in untreated patients

scientific article

Late relapses in acute myeloid leukemia: analysis of characteristics and outcome

scientific article

Lenalidomide as initial therapy of elderly patients with chronic lymphocytic leukemia

scientific article

Lenalidomide induces complete and partial remissions in patients with relapsed and refractory chronic lymphocytic leukemia

scientific article

Lenalidomide induces long-lasting responses in elderly patients with chronic lymphocytic leukemia ⬇️

scientific article published on June 25, 2013

Lenalidomide-induced graft-vs.-Leukemia effect in a patient with chronic lymphocytic leukemia who relapsed after allogeneic stem cell transplant

scientific article

Leukemia cell proliferation and death in chronic lymphocytic leukemia patients on therapy with the BTK inhibitor ibrutinib

scientific article published on 26 January 2017

Long-term Follow-up of Treatment with Ibrutinib and Rituximab in Patients with High-Risk Chronic Lymphocytic Leukemia.

scientific article

Long-term durable remission by cladribine followed by rituximab in patients with hairy cell leukaemia: update of a phase II trial

scientific article published on 15 June 2016

Long-term follow-up of patients receiving allogeneic stem cell transplant for chronic lymphocytic leukaemia: mixed T-cell chimerism is associated with high relapse risk and inferior survival

scientific article published on 14 March 2017

Long-term follow-up of patients with CLL treated with allogeneic hematopoietic transplantation

scientific article published in January 2002

Long-term follow-up results of the combination of topotecan and cytarabine and other intensive chemotherapy regimens in myelodysplastic syndrome

scientific article published in March 2006

Long-term outcomes for patients with chronic lymphocytic leukemia who discontinue ibrutinib

scientific article

Long-term results of first salvage treatment in CLL patients treated initially with FCR (fludarabine, cyclophosphamide, rituximab)

scientific article

Long-term results of the fludarabine, cyclophosphamide, and rituximab regimen as initial therapy of chronic lymphocytic leukemia

scientific article published on 14 April 2008

Low-dose alemtuzumab (Campath) in myeloablative allogeneic stem cell transplantation for CD52-positive malignancies: decreased incidence of acute graft-versus-host-disease with unique pharmacokinetics

scientific article published in April 2004

MYC translocation in chronic lymphocytic leukaemia is associated with increased prolymphocytes and a poor prognosis

scientific article published on 8 May 2008

Management guidelines for use of alemtuzumab in B-cell chronic lymphocytic leukemia

scientific article published on March 2004

Management of adverse events associated with idelalisib treatment: expert panel opinion

scientific article published on March 2015

Management of chronic lymphocytic leukemia: a changing field

scientific article

Management of chronic myeloid leukemia during pregnancy among patients treated with a tyrosine kinase inhibitor: a single-Center experience

scientific article published on 07 December 2020

Mature T-cell leukemias

scientific article

Mayo Clinic office visit. Germs and you. An interview with Michael Keating, M.D.

scientific article published in September 2005

Mechanism of action of SNS-032, a novel cyclin-dependent kinase inhibitor, in chronic lymphocytic leukemia

scientific article published on 20 February 2009

Mechanisms of cell death of chronic lymphocytic leukemia lymphocytes by RNA-directed agent, 8-NH2-adenosine

scientific article published in September 2005

Membranoproliferative glomerulonephritis and acute renal failure in a patient with chronic lymphocytic leukemia: Response to obinutuzumab.

scientific article published on 23 June 2016

Metabolic alterations in highly tumorigenic glioblastoma cells: preference for hypoxia and high dependency on glycolysis

scientific article

Metabolism pathways in chronic lymphocytic leukemia

scientific article published on 8 December 2015

Mitochondrial respiration defects in cancer cells cause activation of Akt survival pathway through a redox-mediated mechanism

scientific article

Molecular differences between small and large cells in patients with chronic lymphocytic leukemia

scientific article

Monoclonal antibodies in chronic lymphocytic leukemia

scientific article published on September 2006

Monoclonal antibody combinations in CLL: evolving strategies

scientific article published on January 2006

Multifaceted actions of 8-amino-adenosine kill BCR–ABL positive cells ⬇️

scientific article published on April 23, 2012

Multiple-dose granulocyte-macrophage-colony-stimulating factor plus 23-valent polysaccharide pneumococcal vaccine in patients with chronic lymphocytic leukemia: a prospective, randomized trial of safety and immunogenicity

scientific article

Multivariable model for time to first treatment in patients with chronic lymphocytic leukemia

scientific article published on 03 October 2011

Myeloid sarcoma is associated with superior event-free survival and overall survival compared with acute myeloid leukemia

scientific article published on September 2008

Myelosuppression after frontline fludarabine, cyclophosphamide, and rituximab in patients with chronic lymphocytic leukemia: analysis of persistent and new-onset cytopenia

scientific article

Mylotarg, fludarabine, cytarabine (ara-C), and cyclosporine (MFAC) regimen as post-remission therapy in acute myelogenous leukemia

scientific article published on 9 September 2003

New aspects of the treatment of chronic lymphocytic leukemia

scientific article published on December 2006

Non-codingRNA sequence variations in human chronic lymphocytic leukemia and colorectal cancer

scientific article

Nonablative allogeneic stem cell transplantation for chronic lymphocytic leukemia: impact of rituximab on immunomodulation and survival

scientific article

Nonmyeloablative allogeneic stem cell transplantation in relapsed/refractory chronic lymphocytic leukemia: long-term follow-up, prognostic factors, and effect of human leukocyte histocompatibility antigen subtype on outcome

scientific article

Nonstochastic pairing of immunoglobulin heavy and light chains expressed by chronic lymphocytic leukemia B cells is predicated on the heavy chain CDR3.

scientific article

Novel immune-based treatment strategies for chronic lymphocytic leukemia

scientific article

Novel role of NOX in supporting aerobic glycolysis in cancer cells with mitochondrial dysfunction and as a potential target for cancer therapy

scientific article

Novel role of p53 in maintaining mitochondrial genetic stability through interaction with DNA Pol gamma

scientific article

OSW-1: a natural compound with potent anticancer activity and a novel mechanism of action

scientific article published on December 2005

Ofatumumab and Lenalidomide for Patients with Relapsed or Refractory Chronic Lymphocytic Leukemia: Correlation between Responses and Immune Characteristics

scientific article published on 05 January 2016

Optimizing treatment for elderly patients with acute promyelocytic leukemia: is it time to replace chemotherapy with all-trans retinoic acid and arsenic trioxide?

scientific article published on November 2006

Other malignancies in chronic lymphocytic leukemia/small lymphocytic lymphoma

scientific article published on 29 December 2008

Outcome of patients with acute myelogenous leukemia after second salvage therapy

scientific article published on August 2005

Outcome with the hyper-CVAD regimens in lymphoblastic lymphoma

scientific article

Outcomes of Patients With Chronic Lymphocytic Leukemia and Richter's Transformation After Transplantation Failure

scientific article published on 6 April 2015

Outcomes of first-line treatment for chronic lymphocytic leukemia with 17p deletion

scientific article

Outcomes of patients with chronic lymphocytic leukemia after discontinuing ibrutinib

scientific article published on 8 January 2015

Outcomes of patients with chronic lymphocytic leukemia treated with first-line idelalisib plus rituximab after cessation of treatment for toxicity

scientific article

Overcoming resistance to histone deacetylase inhibitors in human leukemia with the redox modulating compound β-phenylethyl isothiocyanate

scientific article

Overexpression of the CXCR5 chemokine receptor, and its ligand, CXCL13 in B-cell chronic lymphocytic leukemia

scientific article

PIM kinase inhibitor, AZD1208, inhibits protein translation and induces autophagy in primary chronic lymphocytic leukemia cells

Personalized medicine in CLL: Current status and future perspectives ⬇️

scientific article published on July 20, 2013

Perspectives on the use of new diagnostic tools in the treatment of chronic lymphocytic leukemia

scientific article

Pharmacokinetic and pharmacodynamic evaluation of ibrutinib for the treatment of chronic lymphocytic leukemia: rationale for lower doses

scientific article

Pharmacokinetics and pharmacodynamics of plasma clofarabine and cellular clofarabine triphosphate in patients with acute leukemias.

scientific article published in December 2003

Pharmacological and Protein Profiling Suggests Venetoclax (ABT-199) as Optimal Partner with Ibrutinib in Chronic Lymphocytic Leukemia

scientific article

Pharmacotherapy of relapsed/refractory chronic lymphocytic leukemia.

scientific article published on 26 April 2017

Phase 2 and pharmacodynamic study of oral forodesine in patients with advanced, fludarabine-treated chronic lymphocytic leukemia

scientific article

Phase 2 clinical and pharmacologic study of clofarabine in patients with refractory or relapsed acute leukemia

scientific article

Phase 2 study of cladribine followed by rituximab in patients with hairy cell leukemia ⬇️

scientific article published on August 5, 2011

Phase I clinical and pharmacology study of clofarabine in patients with solid and hematologic cancers.

scientific article published in March 2003

Phase I study of obatoclax mesylate (GX15-070), a small molecule pan-Bcl-2 family antagonist, in patients with advanced chronic lymphocytic leukemia

scientific article

Phase I trial of nelarabine in indolent leukemias

scientific article

Phase I trials using Sleeping Beauty to generate CD19-specific CAR T cells

scientific article published on 02 August 2016

Phase I-II clinical trial of oxaliplatin, fludarabine, cytarabine, and rituximab therapy in aggressive relapsed/refractory chronic lymphocytic leukemia or Richter syndrome

scientific article

Phase I-II study of oxaliplatin, fludarabine, cytarabine, and rituximab combination therapy in patients with Richter's syndrome or fludarabine-refractory chronic lymphocytic leukemia

scientific article published in January 2008

Phase II study of alemtuzumab in chronic lymphoproliferative disorders

scientific article

Phase II study of alemtuzumab in combination with pentostatin in patients with T-cell neoplasms

scientific article

Phase II study of cladribine and cyclophosphamide in patients with chronic lymphocytic leukemia and prolymphocytic leukemia

scientific article

Phase II study of fludarabine, cytarabine (Ara-C), cyclophosphamide, cisplatin and GM-CSF (FACPGM) in patients with Richter's syndrome or refractory lymphoproliferative disorders

scientific article

Phase II study of lenalidomide and rituximab as salvage therapy for patients with relapsed or refractory chronic lymphocytic leukemia

scientific article published on 26 December 2012

Phase II study of single-agent bortezomib for the treatment of patients with fludarabine-refractory B-cell chronic lymphocytic leukemia

scientific article

Pilot experience with continuous infusion alemtuzumab in patients with fludarabine-refractory chronic lymphocytic leukemia

scientific article published on 21 December 2007

Plasma Viral miRNAs Indicate a High Prevalence of Occult Viral Infections

scientific article

Plasma thrombopoietin compared with immunoglobulin heavy-chain mutation status as a predictor of survival in chronic lymphocytic leukemia

scientific article

Preclinical combination of TP-0903, an AXL inhibitor and B-PAC-1, a procaspase-activating compound with ibrutinib in chronic lymphocytic leukemia

scientific article published on 6 October 2015

Predicting survival in chronic lymphocytic leukemia ⬇️

scientific article published on March 1, 2012

Pregnancy among patients with chronic myeloid leukemia treated with imatinib

scientific article published on 30 January 2006

Pregnancy in a patient with hypereosinophilic syndrome

scientific article published on July 2008

Prognostic factors and scoring systems in chronic myelomonocytic leukemia: a retrospective analysis of 213 patients

scientific article (publication date: February 2002)

Prognostic implications of chromosome 17 abnormalities in the context of monosomal karyotype in patients with acute myeloid leukemia and complex cytogenetics

scientific article

Prognostic nomogram and index for overall survival in previously untreated patients with chronic lymphocytic leukemia

scientific article

Prognostic significance of CD20 expression in adults with de novo precursor B-lineage acute lymphoblastic leukemia

scientific article

Prognostic value of miR-155 in individuals with monoclonal B-cell lymphocytosis and patients with B chronic lymphocytic leukemia

scientific article published on 02 July 2013

Proliferation and apoptosis in acute and chronic leukemias and myelodysplastic syndrome

scientific article

Proteasome enzymatic activities in plasma as risk stratification of patients with acute myeloid leukemia and advanced-stage myelodysplastic syndrome

scientific article

Proteasome inhibitor carfilzomib complements ibrutinib's action in chronic lymphocytic leukemia

scientific article published in January 2015

Proteomic-based prediction of clinical behavior in adult acute lymphoblastic leukemia

scientific article

Proteomics profiling identifies induction of caveolin-1 in chronic lymphocytic leukemia cells by bone marrow stromal cells

scientific article published on 3 October 2017

Rapid resolution of Mycobacterium marinum chronic skin infection during lenalidomide therapy for chronic lymphocytic leukemia

scientific article published in April 2008

Reactivation of Smac-mediated apoptosis in chronic lymphocytic leukemia cells: mechanistic studies of Smac mimetic

scientific article published on 29 March 2016

Refractory chronic lymphocytic leukemia complicated by hypercalcemia treated with allogeneic bone marrow transplantation. Case report and review

scientific article published on August 1994

Relative increase in leukemia-specific DNA in peripheral blood plasma from patients with acute myeloid leukemia and myelodysplasia ⬇️

scientific article published on October 23, 2003

Relative value of ZAP-70, CD38, and immunoglobulin mutation status in predicting aggressive disease in chronic lymphocytic leukemia

scientific article published on 24 June 2008

Relevance of the immunoglobulin VH somatic mutation status in patients with chronic lymphocytic leukemia treated with fludarabine, cyclophosphamide, and rituximab (FCR) or related chemoimmunotherapy regimens

scientific article published on 02 December 2008

Results of a phase 1-2 study of clofarabine in combination with cytarabine (ara-C) in relapsed and refractory acute leukemias

scientific article published on 14 October 2004

Results of decitabine (5-aza-2'deoxycytidine) therapy in 130 patients with chronic myelogenous leukemia

scientific article (publication date: August 2003)

Results of second salvage therapy in 673 adults with acute myelogenous leukemia treated at a single institution since 2000.

scientific article published on 12 April 2018

Retrospect of hematological malignancies 2012.

scientific article

Richter syndrome: biology, incidence, and therapeutic strategies

scientific article

Richter transformation of CLL.

scientific article

Richter's transformation in chronic lymphocytic leukemia.

scientific article

Risk categories and refractory CLL in the era of chemoimmunotherapy

scientific article published on 06 March 2012

Rituximab in B-cell disorders other than non-Hodgkin's lymphoma.

scientific article

Rituximab in relapsed or refractory hairy cell leukemia

scientific article

Routine sequencing in CLL has prognostic implications and provides new insight into pathogenesis and targeted treatments

scientific article published on 28 March 2019

Ruxolitinib for symptom control in patients with chronic lymphocytic leukaemia: a single-group, phase 2 trial

scientific article

STAT-3 Activates NF-κB in Chronic Lymphocytic Leukemia Cells ⬇️

scientific article published on March 1, 2011

STAT3 is constitutively acetylated on lysine 685 residues in chronic lymphocytic leukemia cells

STAT3 is constitutively phosphorylated on serine 727 residues, binds DNA, and activates transcription in CLL cells

scientific article

STAT3-Induced Wnt5a Provides Chronic Lymphocytic Leukemia Cells with Survival Advantage

scientific article published on 23 October 2019

STAT3-activated CD36 facilitates fatty acid uptake in chronic lymphocytic leukemia cells.

scientific article

STAT3-activated GM-CSFRα translocates to the nucleus and protects CLL cells from apoptosis

scientific article

Safety and activity of ibrutinib plus rituximab for patients with high-risk chronic lymphocytic leukaemia: a single-arm, phase 2 study

scientific article

Second cancers and Richter transformation are the leading causes of death in patients with trisomy 12 chronic lymphocytic leukemia

scientific article

Second cancers in patients with chronic lymphocytic leukemia who received frontline fludarabine, cyclophosphamide and rituximab therapy: distribution and clinical outcomes

scientific article published on 19 November 2014

Selection of rituximab dosage in chronic lymphocytic leukemia: where is the evidence? ⬇️

scientific article published on September 28, 2012

Self-administered, subcutaneous alemtuzumab to treat residual disease in patients with chronic lymphocytic leukemia

scientific article

Shifting paradigms in the treatment of chronic lymphocytic leukemia

scientific article

Signal transducer and activator of transcription (STAT)-3 regulates microRNA gene expression in chronic lymphocytic leukemia cells

scientific article published on June 2013

Signal transducer and activator of transcription-3 induces microRNA-155 expression in chronic lymphocytic leukemia

scientific article

Simultaneous homoharringtonine and interferon-alpha in the treatment of patients with chronic-phase chronic myelogenous leukemia

scientific article

Single agent thalidomide in patients with relapsed or refractory acute myeloid leukaemia

scientific article published in November 2003

Single-agent liposomal all-trans retinoic acid can cure some patients with untreated acute promyelocytic leukemia: an update of The University of Texas M. D. Anderson Cancer Center Series.

scientific article

SnapShot: chronic lymphocytic leukemia

scientific article published on 10 November 2014

Specific activation of microRNA106b enables the p73 apoptotic response in chronic lymphocytic leukemia by targeting the ubiquitin ligase Itch for degradation

scientific article published on 18 December 2008

Stat3 activates the receptor tyrosine kinase like orphan receptor-1 gene in chronic lymphocytic leukemia cells ⬇️

scientific article published on July 29, 2010

Statin and aspirin use is associated with improved outcome of FCR therapy in relapsed/refractory chronic lymphocytic leukemia

scientific article published on February 2014

Stem cell transplantation for chronic lymphocytic leukemia: should not more patients get a transplant?

scientific article published in August 2004

Stimulation of the B-cell receptor activates the JAK2/STAT3 signaling pathway in chronic lymphocytic leukemia cells

scientific article

Stromal control of cystine metabolism promotes cancer cell survival in chronic lymphocytic leukaemia ⬇️

scientific article published on February 19, 2012

Successful treatment of refractory disseminated Mycobacterium avium complex infection with the addition of linezolid and mefloquine

scientific article published in April 2002

Sudden onset of the blastic phase of chronic myelogenous leukemia: patterns and implications

scientific article published in July 2003

Superoxide dismutase as a target for the selective killing of cancer cells

scientific article published in Nature

Surgical Site Infections after Colon Surgery: What the SIR Doesn’t Tell You.

scientific article published on 4 October 2017

Survival advantage with imatinib mesylate therapy in chronic-phase chronic myelogenous ;eukemia (CML-CP) after IFN-alpha failure and in late CML-CP, comparison with historical controls

scientific article

Systemic depletion of L-cyst(e)ine with cyst(e)inase increases reactive oxygen species and suppresses tumor growth

scientific article

Systemic mastocytosis in association with chronic lymphocytic leukemia: a rare diagnosis

scientific article published on 22 May 2007

T-cell prolymphocytic leukemia: a single-institution experience

scientific article published on 01 November 2005

TAD: a web interface and database for tissue microarrays.

scientific article published on January 2002

Targeting DNA repair in chronic lymphocytic leukemia cells with a novel acyclic nucleotide analogue, GS-9219.

scientific article published on 12 May 2009

Targeting endoplasmic reticulum protein transport: a novel strategy to kill malignant B cells and overcome fludarabine resistance in CLL.

scientific article published on 6 September 2005

Targeting inflammatory pathways in chronic lymphocytic leukemia ⬇️

scientific article published on August 12, 2013

Targeting p53-deficient chronic lymphocytic leukemia cells in vitro and in vivo by ROS-mediated mechanism

scientific article published on 19 September 2016

Telomerase activity is not a prognostic factor in chronic lymphocytic leukemia

scientific article published in July 2004

Thalidomide therapy for myelofibrosis with myeloid metaplasia

scientific article published on 01 May 2006

The Addition of All-Trans Retinoic Acid to Chemotherapy May Not Improve the Outcome of Patient with NPM1 Mutated Acute Myeloid Leukemia

scientific article published on 6 September 2013

The Bruton tyrosine kinase inhibitor PCI-32765 thwarts chronic lymphocytic leukemia cell survival and tissue homing in vitro and in vivo ⬇️

scientific article published on December 16, 2011

The CD38 ectoenzyme family: advances in basic science and clinical practice

scientific article published on November 2006

The CXCR4-STAT3-IL-10 Pathway Controls the Immunoregulatory Function of Chronic Lymphocytic Leukemia and Is Modulated by Lenalidomide

scientific article published in January 2017

The PI3-kinase delta inhibitor idelalisib (GS-1101) targets integrin-mediated adhesion of chronic lymphocytic leukemia (CLL) cell to endothelial and marrow stromal cells

scientific article

The Spiegelmer NOX-A12, a novel CXCL12 inhibitor, interferes with chronic lymphocytic leukemia cell motility and causes chemosensitization

scientific article

The Stromal Microenvironment Modulates Mitochondrial Oxidative Phosphorylation in Chronic Lymphocytic Leukemia Cells

scientific article published on 29 August 2017

The absolute percent deviation of IGHV mutation rather than a 98% cut-off predicts survival of chronic lymphocytic leukaemia patients treated with fludarabine, cyclophosphamide and rituximab

scientific article published on 21 November 2017

The addition of CD20 monoclonal antibodies to lenalidomide improves response rates and survival in relapsed/refractory patients with chronic lymphocytic leukaemia relative to lenalidomide monotherapy - the MD Anderson Cancer Center experience

scientific article published on 30 March 2015

The clinical and diagnostic relevance of CD23 expression in the chronic lymphoproliferative disease

scientific article published in March 2002

The clinical significance of large cells in bone marrow in patients with chronic lymphocytic leukemia

scientific article

The growth factor fusion construct containing B-lymphocyte stimulator (BLyS) and the toxin rGel induces apoptosis specifically in BAFF-R-positive CLL cells

scientific article published on 21 November 2006

The landscape of genetic mutations in patients with chronic lymphocytic leukaemia and complex karyotype

scientific article published on 25 July 2019

The phosphoinositide 3′-kinase delta inhibitor, CAL-101, inhibits B-cell receptor signaling and chemokine networks in chronic lymphocytic leukemia ⬇️

scientific article published on July 29, 2011

The prognostic difference of monoallelic versus biallelic deletion of 13q in chronic lymphocytic leukemia

scientific article

The prognostic significance of serum beta2 microglobulin levels in acute myeloid leukemia and prognostic scores predicting survival: analysis of 1,180 patients

scientific article

The proteasome inhibitor NPI-0052 is a more effective inducer of apoptosis than bortezomib in lymphocytes from patients with chronic lymphocytic leukemia

scientific article published in July 2006

The proteasome inhibitor PS-341 inhibits growth and induces apoptosis in Bcr/Abl-positive cell lines sensitive and resistant to imatinib mesylate

scientific article published in August 2003

The role of clofarabine in hematologic and solid malignancies--development of a next-generation nucleoside analog

scientific article

The role of cytogenetic abnormalities as a prognostic marker in primary myelofibrosis: applicability at the time of diagnosis and later during disease course

scientific article published on 8 January 2009

The role of gemtuzumab ozogamicin in acute leukaemia therapy

scientific article

The significance of spliceosome mutations in chronic lymphocytic leukemia

scientific article

The synthetic heat shock protein 90 (Hsp90) inhibitor EC141 induces degradation of Bcr-Abl p190 protein and apoptosis of Ph-positive acute lymphoblastic leukemia cells

scientific article

Therapeutic advances in leukemia and myelodysplastic syndrome over the past 40 years

scientific article published on October 2008

Therapeutic role of alemtuzumab (Campath-1H) in patients who have failed fludarabine: results of a large international study

scientific article

Three newly approved drugs for chronic lymphocytic leukemia: incorporating ibrutinib, idelalisib, and obinutuzumab into clinical practice

scientific article published on 19 February 2015

Toward the potential cure of leukemias in the next decade

scientific article published on 06 October 2018

Transcription inhibition by flavopiridol: mechanism of chronic lymphocytic leukemia cell death

scientific article published on 21 June 2005

Transient down-modulation of CD20 by rituximab in patients with chronic lymphocytic leukemia

scientific article

Transplant-lite: induction of graft-versus-malignancy using fludarabine-based nonablative chemotherapy and allogeneic blood progenitor-cell transplantation as treatment for lymphoid malignancies ⬇️

scientific article published on 01 August 1998

Treatment of Philadelphia chromosome-positive acute lymphocytic leukemia with hyper-CVAD and imatinib mesylate

scientific article published on 9 October 2003

Treatment of fludarabine-refractory chronic lymphocytic leukemia

scientific article

Treatment of patients with fludarabine-refractory chronic lymphocytic leukemia: need for new treatment options

scientific article published on July 2010

Treatment of philadelphia chromosome-positive, accelerated-phase chronic myelogenous leukemia with imatinib mesylate.

scientific article

Treatment with lenalidomide modulates T‐cell immunophenotype and cytokine production in patients with chronic lymphocytic leukemia ⬇️

scientific article published on February 24, 2011

Trisomy 12 chronic lymphocytic leukemia expresses a unique set of activated and targetable pathways

scholarly article by Lynne V Abruzzo et al published 5 July 2018 in Haematologica

Trisomy 12 is associated with an abbreviated redistribution lymphocytosis during treatment with the BTK inhibitor ibrutinib in patients with chronic lymphocytic leukaemia

scientific article published on 18 December 2014

UCN-01 (7-hydroxystaurosporine) inhibits DNA repair and increases cytotoxicity in normal lymphocytes and chronic lymphocytic leukemia lymphocytes.

scientific article published in February 2002

Updated guidelines on the management of cytomegalovirus reactivation in patients with chronic lymphocytic leukemia treated with alemtuzumab

scientific article published on September 2006

Use of CAR-Transduced Natural Killer Cells in CD19-Positive Lymphoid Tumors

scientific article published on 01 February 2020

Use of IGHV3-21 in chronic lymphocytic leukemia is associated with high-risk disease and reflects antigen-driven, post-germinal center leukemogenic selection

scientific article published on 7 March 2008

Valganciclovir prevents cytomegalovirus reactivation in patients receiving alemtuzumab-based therapy

scientific article published on 26 November 2007

Validation of oligonucleotide microarray data using microfluidic low-density arrays: a new statistical method to normalize real-time RT-PCR data

scientific article

What is the Best Frontline Therapy for Patients with CLL and 17p Deletion? ⬇️

scientific article published on March 1, 2011

Whole-genome scanning by array comparative genomic hybridization as a clinical tool for risk assessment in chronic lymphocytic leukemia

scientific article

Yttrium-90 ibritumomab tiuxetan radioimmunotherapy in Richter syndrome

scientific article

ZAP-70 compared with immunoglobulin heavy-chain gene mutation status as a predictor of disease progression in chronic lymphocytic leukemia

scientific article published in August 2004

miRNAs involvement in the pathogenesis of Richter's syndrome

scholarly article by Katrien Van Roosbroeck et al published 8 November 2018 in Haematologica

microRNA fingerprinting of CLL patients with chromosome 17p deletion identify a miR-21 score that stratifies early survival

scientific article published on 14 April 2010

p53 expression by immunohistochemistry is an important determinant of survival in patients with chronic lymphocytic leukemia receiving frontline chemo-immunotherapy

scientific article published on October 2009

β2 -microglobulin normalization within 6 months of ibrutinib-based treatment is associated with superior progression-free survival in patients with chronic lymphocytic leukemia

scientific article published on 20 November 2015

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