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List of works by Beate Schwer

A conformational rearrangement in the spliceosome sets the stage for Prp22-dependent mRNA release

scientific article

A function of yeast mRNA cap methyltransferase, Abd1, in transcription by RNA polymerase II.

scientific article

A fungal anticodon nuclease ribotoxin exploits a secondary cleavage site to evade tRNA repair

scientific article

A long noncoding (lnc) RNA governs expression of the phosphate transporter Pho84 in fission yeast and has cascading effects on the flanking prt lncRNA and pho1 genes

scientific article published on 2 February 2018

A positive feedback loop links opposing functions of P-TEFb/Cdk9 and histone H2B ubiquitylation to regulate transcript elongation in fission yeast

scientific article

ATP-dependent remodeling of the spliceosome: intragenic suppressors of release-defective mutants of Saccharomyces cerevisiae Prp22

scientific article

An encephalitozoon cuniculi ortholog of the RNA polymerase II carboxyl-terminal domain (CTD) serine phosphatase Fcp1.

scientific article

An essential role for trimethylguanosine RNA caps in Saccharomyces cerevisiae meiosis and their requirement for splicing of SAE3 and PCH2 meiotic pre - mRNAs ⬇️

scientific article published on March 11, 2011

Biochemical and genetic analysis of RNA cap guanine-N2 methyltransferases from Giardia lamblia and Schizosaccharomyces pombe

scientific article published on 6 February 2007

Characterization of a mimivirus RNA cap guanine-N2 methyltransferase

scientific article published on 13 February 2009

Characterization of the NTPase, RNA-binding, and RNA helicase activities of the DEAH-box splicing factor Prp22.

scientific article

Characterization of the Schizosaccharomyces pombe Spt5-Spt4 complex

scientific article published on 21 May 2009

Characterization of the tRNA ligases of pathogenic fungi Aspergillus fumigatus and Coccidioides immitis

scientific article published on 4 August 2016

Composition of yeast snRNPs and snoRNPs in the absence of trimethylguanosine caps reveals nuclear cap binding protein as a gained U1 component implicated in the cold-sensitivity of tgs1Δ cells

scientific article

Crystal structure, mutational analysis and RNA-dependent ATPase activity of the yeast DEAD-box pre-mRNA splicing factor Prp28.

scientific article

Deciphering the RNA Polymerase II CTD Code in Fission Yeast ⬇️

scientific article published on June 23, 2011

Defining essential elements and genetic interactions of the yeast Lsm2-8 ring and demonstration that essentiality of Lsm2-8 is bypassed via overexpression of U6 snRNA or the U6 snRNP subunit Prp24.

scientific article published on 3 April 2018

Defining the DNA Binding Site Recognized by the Fission Yeast Zn2Cys6 Transcription Factor Pho7 and Its Role in Phosphate Homeostasis

scientific article published on 15 August 2017

Defining the Mer1 and Nam8 meiotic splicing regulons by cDNA rescue

scientific article

Determinants of Nam8-dependent splicing of meiotic pre-mRNAs ⬇️

scientific article published on January 5, 2011

Determinants of eukaryal cell killing by the bacterial ribotoxin PrrC.

scientific article

Distinctive structural basis for DNA recognition by the fission yeast Zn2Cys6 transcription factor Pho7 and its role in phosphate homeostasis.

scientific article published in November 2018

Domain Requirements and Genetic Interactions of the Mud1 Subunit of the Saccharomyces cerevisiae U1 snRNP.

scientific article

Fission yeast RNA triphosphatase reads an Spt5 CTD code

scientific article

Functional interaction of Rpb1 and Spt5 C-terminal domains in co-transcriptional histone modification

scientific article published on 14 August 2015

Functional interactions between Prp8, Prp18, Slu7, and U5 snRNA during the second step of pre-mRNA splicing

scientific article

Genetic analysis of poxvirus mRNA cap methyltransferase: suppression of conditional mutations in the stimulatory D12 subunit by second-site mutations in the catalytic D1 subunit

scientific article published on 23 May 2006

Genetic and biochemical analysis of the functional domains of yeast tRNA ligase

scientific article published on 21 August 2003

Genetic and biochemical analysis of yeast and human cap trimethylguanosine synthase: functional overlap of 2,2,7-trimethylguanosine caps, small nuclear ribonucleoprotein components, pre-mRNA splicing factors, and RNA decay pathways

scientific article published on 05 September 2008

Genetic and structural analysis of the essential fission yeast RNA polymerase II CTD phosphatase Fcp1.

scientific article published on 16 April 2015

Genetic interactions of hypomorphic mutations in the m7G cap-binding pocket of yeast nuclear cap binding complex: an essential role for Cbc2 in meiosis via splicing of MER3 pre-mRNA

scientific article

How Slu7 and Prp18 cooperate in the second step of yeast pre-mRNA splicing

scientific article

How an mRNA capping enzyme reads distinct RNA polymerase II and Spt5 CTD phosphorylation codes

scientific article

Human RNA 5'-kinase (hClp1) can function as a tRNA splicing enzyme in vivo

scientific article published on 22 July 2008

Individual letters of the RNA polymerase II CTD code govern distinct gene expression programs in fission yeast

scientific article

Mammalian 2',3' cyclic nucleotide phosphodiesterase (CNP) can function as a tRNA splicing enzyme in vivo

scientific article published on 19 December 2007

Mechanistic insights into the manganese-dependent phosphodiesterase activity of yeast Dbr1 with bis-p-nitrophenylphosphate and branched RNA substrates

scientific article published on 7 October 2016

Motifs IV and V in the DEAH box splicing factor Prp22 are important for RNA unwinding, and helicase-defective Prp22 mutants are suppressed by Prp8.

scientific article published on 19 December 2003

Mutational Analysis ofEncephalitozoon cuniculimRNA Cap (Guanine-N7) Methyltransferase, Structure of the Enzyme Bound to Sinefungin, and Evidence That Cap Methyltransferase Is the Target of Sinefungin's Antifungal Activity

scientific article published in Journal of Biological Chemistry

Mutational analyses of trimethylguanosine synthase (Tgs1) and Mud2: proteins implicated in pre-mRNA splicing

scientific article

Mutations in PRP43 that uncouple RNA-dependent NTPase activity and pre-mRNA splicing function

scientific article published on May 2006

Ntr1 activates the Prp43 helicase to trigger release of lariat-intron from the spliceosome

scientific article

Phospho-site mutants of the RNA Polymerase II C-terminal domain alter subtelomeric gene expression and chromatin modification state in fission yeast

scientific article published on 08 July 2016

Poly(A) site choice and Pol2 CTD Serine-5 status govern lncRNA control of phosphate-responsive tgp1 gene expression in fission yeast

scientific article published on 9 November 2017

Portability and fidelity of RNA-repair systems

scholarly article

Poxvirus mRNA cap methyltransferase. Bypass of the requirement for the stimulatory subunit by mutations in the catalytic subunit and evidence for intersubunit allostery

scientific article published on 16 May 2006

Prp43 is an essential RNA-dependent ATPase required for release of lariat-intron from the spliceosome

scientific article

Punctuation and syntax of the RNA polymerase II CTD code in fission yeast

scientific article published on 15 October 2012

RNA polymerase II CTD phospho-sites Ser5 and Ser7 govern phosphate homeostasis in fission yeast

scientific article

RNA repair: an antidote to cytotoxic eukaryal RNA damage

scientific article published on July 2008

Separable functions of the fission yeast Spt5 carboxyl-terminal domain (CTD) in capping enzyme binding and transcription elongation overlap with those of the RNA polymerase II CTD

scientific article

Sinefungin resistance of Saccharomyces cerevisiae arising from Sam3 mutations that inactivate the AdoMet transporter or from increased expression of AdoMet synthase plus mRNA cap guanine-N7 methyltransferase

scientific article

Structural basis for recognition of intron branchpoint RNA by yeast Msl5 and selective effects of interfacial mutations on splicing of yeast pre-mRNAs

scientific article

Structure-function analysis and genetic interactions of the Luc7 subunit of the Saccharomyces cerevisiae U1 snRNP.

scientific article published on 27 June 2016

Structure-function analysis and genetic interactions of the SmG, SmE, and SmF subunits of the yeast Sm protein ring

scientific article published on 14 July 2016

Structure-function analysis and genetic interactions of the Yhc1, SmD3, SmB, and Snp1 subunits of yeast U1 snRNP and genetic interactions of SmD3 with U2 snRNP subunit Lea1.

scientific article published on 20 April 2015

Structure-function analysis of the 5' end of yeast U1 snRNA highlights genetic interactions with the Msl5*Mud2 branchpoint-binding complex and other spliceosome assembly factors

scientific article published on 10 June 2013

Structure-function analysis of the Yhc1 subunit of yeast U1 snRNP and genetic interactions of Yhc1 with Mud2, Nam8, Mud1, Tgs1, U1 snRNA, SmD3 and Prp28.

scientific article published on 04 February 2014

Structure-function analysis of the kinase-CPD domain of yeast tRNA ligase (Trl1) and requirements for complementation of tRNA splicing by a plant Trl1 homolog

scientific article

Structure-function analysis of the yeast NAD+-dependent tRNA 2'-phosphotransferase Tpt1

scientific article

Structure-function analysis of yeast RNA debranching enzyme (Dbr1), a manganese-dependent phosphodiesterase

scientific article

Structure-guided mutational analysis of T4 RNA ligase 1.

scientific article

Structure–function analysis and genetic interactions of the yeast branchpoint binding protein Msl5 ⬇️

scientific article published on January 28, 2012

TFIIH and P-TEFb coordinate transcription with capping enzyme recruitment at specific genes in fission yeast

scientific article published on March 2009

Tat stimulates cotranscriptional capping of HIV mRNA.

scientific article

The C-terminal domain of T4 RNA ligase 1 confers specificity for tRNA repair

scientific article published on 21 June 2007

The PAF complex and Prf1/Rtf1 delineate distinct Cdk9-dependent pathways regulating transcription elongation in fission yeast

scientific article

Transcription of lncRNA prt, clustered prt RNA sites for Mmi1 binding, and RNA polymerase II CTD phospho-sites govern the repression of pho1 gene expression under phosphate-replete conditions in fission yeast

scientific article published on 10 May 2016

Two Routes to Genetic Suppression of RNA Trimethylguanosine Cap Deficiency via C-Terminal Truncation of U1 snRNP Subunit Snp1 or Overexpression of RNA Polymerase Subunit Rpo26

scientific article published on 24 April 2015

Will the circle be unbroken: specific mutations in the yeast Sm protein ring expose a requirement for assembly factor Brr1, a homolog of Gemin2.

scientific article published on 14 December 2016

Yeast-based genetic system for functional analysis of poxvirus mRNA cap methyltransferase

scientific article published on July 2003

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