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List of works by Stewart Shuman

2'-Phosphate cyclase activity of RtcA: a potential rationale for the operon organization of RtcA with an RNA repair ligase RtcB in Escherichia coli and other bacterial taxa

scientific article published on 14 August 2013

A dual role for mycobacterial RecO in RecA-dependent homologous recombination and RecA-independent single-strand annealing

scientific article published on 7 January 2013

A function of yeast mRNA cap methyltransferase, Abd1, in transcription by RNA polymerase II.

scientific article

A fungal anticodon nuclease ribotoxin exploits a secondary cleavage site to evade tRNA repair

scientific article

A kinetic framework for tRNA ligase and enforcement of a 2'-phosphate requirement for ligation highlights the design logic of an RNA repair machine

scientific article published on 20 March 2013

A long noncoding (lnc) RNA governs expression of the phosphate transporter Pho84 in fission yeast and has cascading effects on the flanking prt lncRNA and pho1 genes

scientific article published on 2 February 2018

A phosphate-binding histidine of binuclear metallophosphodiesterase enzymes is a determinant of 2',3'-cyclic nucleotide phosphodiesterase activity

scientific journal article

A primer-dependent polymerase function of pseudomonas aeruginosa ATP-dependent DNA ligase (LigD)

scientific journal article

Active site mapping and substrate specificity of bacterial Hen1, a manganese-dependent 3' terminal RNA ribose 2'O-methyltransferase

scientific article

An RNA ligase from Deinococcus radiodurans

scientific article

An encephalitozoon cuniculi ortholog of the RNA polymerase II carboxyl-terminal domain (CTD) serine phosphatase Fcp1.

scientific article

An end-healing enzyme from Clostridium thermocellum with 5' kinase, 2',3' phosphatase, and adenylyltransferase activities

scientific article

An essential role for trimethylguanosine RNA caps in Saccharomyces cerevisiae meiosis and their requirement for splicing of SAE3 and PCH2 meiotic pre - mRNAs ⬇️

scientific article published on March 11, 2011

Analysis of the DNA joining repertoire of Chlorella virus DNA ligase and a new crystal structure of the ligase-adenylate intermediate

scientific article

Arabidopsis C-terminal domain phosphatase-like 1 and 2 are essential Ser-5-specific C-terminal domain phosphatases

scholarly article

Atomic force microscopy shows that vaccinia topoisomerase IB generates filaments on DNA in a cooperative fashion

scientific article

Bacterial nonhomologous end joining ligases preferentially seal breaks with a 3'-OH monoribonucleotide

scientific article published on 17 January 2008

Bacteriophage T4 RNA ligase 2 (gp24.1) exemplifies a family of RNA ligases found in all phylogenetic domains

scientific article

Benzo[c]phenanthrene adducts and nogalamycin inhibit DNA transesterification by vaccinia topoisomerase

scientific article published on 23 March 2004

Biochemical and genetic analysis of RNA cap guanine-N2 methyltransferases from Giardia lamblia and Schizosaccharomyces pombe

scientific article published on 6 February 2007

Box H/ACA snoRNAs are preferred substrates for the trimethylguanosine synthase in the divergent unicellular eukaryote Trichomonas vaginalis

scientific article

Cap analog substrates reveal three clades of cap guanine-N2 methyltransferases with distinct methyl acceptor specificities

scientific article

Cellular strategies for regulating DNA supercoiling: a single-molecule perspective

scientific article published on August 2010

Characterization of 3'-Phosphate RNA Ligase Paralogs RtcB1, RtcB2, and RtcB3 from Myxococcus xanthus Highlights DNA and RNA 5'-Phosphate Capping Activity of RtcB3.

scientific article

Characterization of Agrobacterium tumefaciens DNA ligases C and D

scientific article published on 8 May 2007

Characterization of Mycobacterium smegmatis PolD2 and PolD1 as RNA/DNA polymerases homologous to the POL domain of bacterial DNA ligase D.

scientific article published on 11 December 2012

Characterization of Runella slithyformis HD-Pnk, a bifunctional DNA/RNA end-healing enzyme composed of an N-terminal 2',3' -phosphoesterase HD domain and a C-terminal 5' -OH polynucleotide kinase domain

scientific article published on 28 November 2016

Characterization of a baculovirus enzyme with RNA ligase, polynucleotide 5'-kinase, and polynucleotide 3'-phosphatase activities

scientific article published on 26 January 2004

Characterization of a mimivirus RNA cap guanine-N2 methyltransferase

scientific article published on 13 February 2009

Characterization of bacteriophage KVP40 and T4 RNA ligase 2.

scientific article published in February 2004

Characterization of mimivirus DNA topoisomerase IB suggests horizontal gene transfer between eukaryal viruses and bacteria

scientific article published on January 2006

Characterization of mimivirus NAD+-dependent DNA ligase

scientific article published on 14 July 2006

Characterization of polynucleotide kinase/phosphatase enzymes from Mycobacteriophages omega and Cjw1 and vibriophage KVP40.

scientific article

Characterization of the 2',3' cyclic phosphodiesterase activities of Clostridium thermocellum polynucleotide kinase-phosphatase and bacteriophage lambda phosphatase

scientific article

Characterization of the CTD phosphatase Fcp1 from fission yeast. Preferential dephosphorylation of serine 2 versus serine 5.

scientific article

Characterization of the Schizosaccharomyces pombe Cdk9/Pch1 protein kinase: Spt5 phosphorylation, autophosphorylation, and mutational analysis

scientific article published on 5 August 2003

Characterization of the Schizosaccharomyces pombe Spt5-Spt4 complex

scientific article published on 21 May 2009

Characterization of the tRNA ligases of pathogenic fungi Aspergillus fumigatus and Coccidioides immitis

scientific article published on 4 August 2016

Characterization of three mycobacterial DinB (DNA polymerase IV) paralogs highlights DinB2 as naturally adept at ribonucleotide incorporation

scientific article

Chlorella virus RNA triphosphatase. Mutational analysis and mechanism of inhibition by tripolyphosphate

scientific article published on 13 February 2002

Composition of yeast snRNPs and snoRNPs in the absence of trimethylguanosine caps reveals nuclear cap binding protein as a gained U1 component implicated in the cold-sensitivity of tgs1Δ cells

scientific article

Crystal Structure and Biochemical Characterization of a Mycobacterium smegmatis AAA-Type Nucleoside Triphosphatase Phosphohydrolase (Msm0858).

scientific article published on 7 March 2016

Crystal Structure of Vaccinia Virus mRNA Capping Enzyme Provides Insights into the Mechanism and Evolution of the Capping Apparatus

scientific article published on 4 March 2014

Crystal structure and mutational analysis of Mycobacterium smegmatis FenA highlight active site amino acids and three metal ions essential for flap endonuclease and 5' exonuclease activities

scientific article published on 9 April 2018

Crystal structure and nonhomologous end-joining function of the ligase component of Mycobacterium DNA ligase D.

scientific article published on 13 February 2006

Crystal structure of Rcl1, an essential component of the eukaryal pre-rRNA processosome implicated in 18s rRNA biogenesis

scientific article

Crystal structure, mutational analysis and RNA-dependent ATPase activity of the yeast DEAD-box pre-mRNA splicing factor Prp28.

scientific article

Cyclin-dependent kinase 9 (Cdk9) of fission yeast is activated by the CDK-activating kinase Csk1, overlaps functionally with the TFIIH-associated kinase Mcs6, and associates with the mRNA cap methyltransferase Pcm1 in vivo

scientific article

DNA3'pp5'G de-capping activity of aprataxin: effect of cap nucleoside analogs and structural basis for guanosine recognition

scientific article published on 24 May 2015

Deciphering the RNA Polymerase II CTD Code in Fission Yeast ⬇️

scientific article published on June 23, 2011

Defining essential elements and genetic interactions of the yeast Lsm2-8 ring and demonstration that essentiality of Lsm2-8 is bypassed via overexpression of U6 snRNA or the U6 snRNP subunit Prp24.

scientific article published on 3 April 2018

Defining the DNA Binding Site Recognized by the Fission Yeast Zn2Cys6 Transcription Factor Pho7 and Its Role in Phosphate Homeostasis

scientific article published on 15 August 2017

Defining the Mer1 and Nam8 meiotic splicing regulons by cDNA rescue

scientific article

Defining the active site of Schizosaccharomyces pombe C-terminal domain phosphatase Fcp1.

scientific article

Deinococcus radiodurans HD-Pnk, a Nucleic Acid End-Healing Enzyme, Abets Resistance to Killing by Ionizing Radiation and Mitomycin C

article published in 2018

Deinococcus radiodurans RNA ligase exemplifies a novel ligase clade with a distinctive N-terminal module that is important for 5'-PO4 nick sealing and ligase adenylylation but dispensable for phosphodiester formation at an adenylylated nick

scientific article

Deletion of the rnl gene encoding a nick-sealing RNA ligase sensitizes Deinococcus radiodurans to ionizing radiation

scientific article

Determinants of Nam8-dependent splicing of meiotic pre-mRNAs ⬇️

scientific article published on January 5, 2011

Determinants of eukaryal cell killing by the bacterial ribotoxin PrrC.

scientific article

Determinants of the cytotoxicity of PrrC anticodon nuclease and its amelioration by tRNA repair

scientific article published on 18 November 2011

Different strategies for carboxyl-terminal domain (CTD) recognition by serine 5-specific CTD phosphatases

scientific article

Discrimination of RNA from DNA by polynucleotide phosphorylase

scientific article published on 11 September 2013

Distinct Contributions of Enzymic Functional Groups to the 2',3'-Cyclic Phosphodiesterase, 3'-Phosphate Guanylylation, and 3'-ppG/5'-OH Ligation Steps of the Escherichia coli RtcB Nucleic Acid Splicing Pathway

scientific article published on 8 February 2016

Distinctive effects of domain deletions on the manganese-dependent DNA polymerase and DNA phosphorylase activities of Mycobacterium smegmatis polynucleotide phosphorylase

scientific article published on 18 April 2013

Distinctive kinetics and substrate specificities of plant and fungal tRNA ligases

scientific article published on 19 February 2014

Distinctive structural basis for DNA recognition by the fission yeast Zn2Cys6 transcription factor Pho7 and its role in phosphate homeostasis.

scientific article published in November 2018

Division of labor among Mycobacterium smegmatis RNase H enzymes: RNase H1 activity of RnhA or RnhC is essential for growth whereas RnhB and RnhA guard against killing by hydrogen peroxide in stationary phase

scientific article

Domain Requirements and Genetic Interactions of the Mud1 Subunit of the Saccharomyces cerevisiae U1 snRNP.

scientific article

Domain requirements for DNA unwinding by mycobacterial UvrD2, an essential DNA helicase

scientific article published on 15 August 2008

Dual mechanisms whereby a broken RNA end assists the catalysis of its repair by T4 RNA ligase 2.

scientific article published on 25 April 2005

Dynamics of phosphodiester synthesis by DNA ligase

scholarly article

Effects of 3'-OH and 5'-PO4 base mispairs and damaged base lesions on the fidelity of nick sealing by Deinococcus radiodurans RNA ligase

scientific article published on 14 February 2014

Effects of DNA3'pp5'G capping on 3' end repair reactions and of an embedded pyrophosphate-linked guanylate on ribonucleotide surveillance

scientific article

Encephalitozoon cuniculi mRNA cap (guanine N-7) methyltransferase: methyl acceptor specificity, inhibition BY S-adenosylmethionine analogs, and structure-guided mutational analysis

scientific article

Essential constituents of the 3'-phosphoesterase domain of bacterial DNA ligase D, a nonhomologous end-joining enzyme

scientific article published on 25 July 2005

Fcp1 directly recognizes the C-terminal domain (CTD) and interacts with a site on RNA polymerase II distinct from the CTD.

scientific article

Fission yeast RNA triphosphatase reads an Spt5 CTD code

scientific article

Friction and torque govern the relaxation of DNA supercoils by eukaryotic topoisomerase IB.

scientific article

Functional dissection of the DNA interface of the nucleotidyltransferase domain of chlorella virus DNA ligase

scientific article

Functional interaction of Rpb1 and Spt5 C-terminal domains in co-transcriptional histone modification

scientific article published on 14 August 2015

Gap filling activities of Pseudomonas DNA ligase D (LigD) polymerase and functional interactions of LigD with the DNA end-binding Ku protein

scientific journal article

Genetic analysis of poxvirus mRNA cap methyltransferase: suppression of conditional mutations in the stimulatory D12 subunit by second-site mutations in the catalytic D1 subunit

scientific article published on 23 May 2006

Genetic and biochemical analysis of the functional domains of yeast tRNA ligase

scientific article published on 21 August 2003

Genetic and biochemical analysis of yeast and human cap trimethylguanosine synthase: functional overlap of 2,2,7-trimethylguanosine caps, small nuclear ribonucleoprotein components, pre-mRNA splicing factors, and RNA decay pathways

scientific article published on 05 September 2008

Genetic and structural analysis of the essential fission yeast RNA polymerase II CTD phosphatase Fcp1.

scientific article published on 16 April 2015

Genetic interactions of hypomorphic mutations in the m7G cap-binding pocket of yeast nuclear cap binding complex: an essential role for Cbc2 in meiosis via splicing of MER3 pre-mRNA

scientific article

Giardia lamblia RNA cap guanine-N2 methyltransferase (Tgs2).

scientific article published on 25 July 2005

Homodimeric quaternary structure is required for the in vivo function and thermal stability of Saccharomyces cerevisiae and Schizosaccharomyces pombe RNA triphosphatases

scientific article

Homologous recombination mediated by the mycobacterial AdnAB helicase without end resection by the AdnAB nucleases

scientific article

How an RNA ligase discriminates RNA versus DNA damage

scientific article published in October 2004

How an mRNA capping enzyme reads distinct RNA polymerase II and Spt5 CTD phosphorylation codes

scientific article

Human RNA 5'-kinase (hClp1) can function as a tRNA splicing enzyme in vivo

scientific article published on 22 July 2008

Impact of DNA3'pp5'G capping on repair reactions at DNA 3' ends

scientific article

Individual letters of the RNA polymerase II CTD code govern distinct gene expression programs in fission yeast

scientific article

Interactions between fission yeast mRNA capping enzymes and elongation factor Spt5.

scientific article published on 13 March 2002

Intercalating polycyclic aromatic hydrocarbon-DNA adducts poison DNA religation by Vaccinia topoisomerase and act as roadblocks to digestion by exonuclease III.

scientific article

Kinetic Analysis of DNA Strand Joining by Chlorella Virus DNA Ligase and the Role of Nucleotidyltransferase Motif VI in Ligase Adenylylation ⬇️

scientific article published on June 28, 2012

Kinetic mechanism and fidelity of nick sealing by Escherichia coli NAD+-dependent DNA ligase (LigA).

scientific article published on 8 February 2016

Kinetic mechanism of nick sealing by T4 RNA ligase 2 and effects of 3'-OH base mispairs and damaged base lesions

scientific article published on 24 October 2013

Last stop on the road to repair: structure of E. coli DNA ligase bound to nicked DNA-adenylate

scientific article

Mammalian 2',3' cyclic nucleotide phosphodiesterase (CNP) can function as a tRNA splicing enzyme in vivo

scientific article published on 19 December 2007

Mapping the active site of vaccinia virus RNA triphosphatase ⬇️

scientific article published on April 25, 2003

Mapping the triphosphatase active site of baculovirus mRNA capping enzyme LEF4 and evidence for a two-metal mechanism

scientific article

Mechanism of RNA 2',3'-cyclic phosphate end healing by T4 polynucleotide kinase-phosphatase

scientific article published on 30 October 2012

Mechanism of nonhomologous end-joining in mycobacteria: a low-fidelity repair system driven by Ku, ligase D and ligase C

scientific journal article

Mechanism of the phosphatase component of Clostridium thermocellum polynucleotide kinase-phosphatase

scientific article published on 21 November 2005

Mechanistic insights into the manganese-dependent phosphodiesterase activity of yeast Dbr1 with bis-p-nitrophenylphosphate and branched RNA substrates

scientific article published on 7 October 2016

Mechanistic plasticity of DNA topoisomerase IB: phosphate electrostatics dictate the need for a catalytic arginine

scientific article

Mutational Analysis of 39 Residues of Vaccinia DNA Topoisomerase Identifies Lys-220, Arg-223, and Asn-228 as Important for Covalent Catalysis

scientific article published on 01 March 1997

Mutational Analysis ofEncephalitozoon cuniculimRNA Cap (Guanine-N7) Methyltransferase, Structure of the Enzyme Bound to Sinefungin, and Evidence That Cap Methyltransferase Is the Target of Sinefungin's Antifungal Activity

scientific article published in Journal of Biological Chemistry

Mutational analyses of trimethylguanosine synthase (Tgs1) and Mud2: proteins implicated in pre-mRNA splicing

scientific article

Mutational analysis defines the 5'-kinase and 3'-phosphatase active sites of T4 polynucleotide kinase

scientific article published on February 2002

Mutational analysis of Mycobacterium UvrD1 identifies functional groups required for ATP hydrolysis, DNA unwinding, and chemomechanical coupling

scientific article published on May 2009

Mutational analysis of bacteriophage T4 RNA ligase 1. Different functional groups are required for the nucleotidyl transfer and phosphodiester bond formation steps of the ligation reaction

scientific article published on 24 May 2003

Mutational analysis of baculovirus phosphatase identifies structural residues important for triphosphatase activity in vitro and in vivo

scientific article published in November 2002

Mutational analysis of the 5'-OH oligonucleotide phosphate acceptor site of T4 polynucleotide kinase

scientific article

Mutational analysis of the guanylyltransferase component of Mammalian mRNA capping enzyme

scientific article published on July 2003

Mutational analysis of vaccinia virus mRNA cap (guanine-N7) methyltransferase reveals essential contributions of the N-terminal peptide that closes over the active site

scientific article published on 17 September 2008

Mycobacterial nonhomologous end joining mediates mutagenic repair of chromosomal double-strand DNA breaks

scientific article

Mycobacterium smegmatis DinB2 misincorporates deoxyribonucleotides and ribonucleotides during templated synthesis and lesion bypass

scientific article

Mycobacterium smegmatis HelY Is an RNA-Activated ATPase/dATPase and 3'-to-5' Helicase That Unwinds 3'-Tailed RNA Duplexes and RNA:DNA Hybrids

scientific article

Mycobacterium smegmatis Lhr Is a DNA-dependent ATPase and a 3'-to-5' DNA translocase and helicase that prefers to unwind 3'-tailed RNA:DNA hybrids

scientific article published on 2 April 2013

Mycobacterium smegmatis RqlH defines a novel clade of bacterial RecQ-like DNA helicases with ATP-dependent 3′–5′ translocase and duplex unwinding activities ⬇️

scientific article published on January 28, 2012

Mycobacterium smegmatis SftH exemplifies a distinctive clade of superfamily II DNA-dependent ATPases with 3′ to 5′ translocase and helicase activities ⬇️

scientific article published on May 27, 2012

NAD+-dependent synthesis of a 5'-phospho-ADP-ribosylated RNA/DNA cap by RNA 2'-phosphotransferase Tpt1

Nanomolar Inhibitors of Trypanosoma brucei RNA Triphosphatase

scientific article

Novel 3'-ribonuclease and 3'-phosphatase activities of the bacterial non-homologous end-joining protein, DNA ligase D

scientific journal article

Novel Mechanism of RNA Repair by RtcB via Sequential 2′,3′-Cyclic Phosphodiesterase and 3′-Phosphate/5′-Hydroxyl Ligation Reactions ⬇️

scientific article published on October 31, 2011

Novel triphosphate phosphohydrolase activity of Clostridium thermocellum TTM, a member of the triphosphate tunnel metalloenzyme superfamily

scientific article

Nucleotide misincorporation, 3'-mismatch extension, and responses to abasic sites and DNA adducts by the polymerase component of bacterial DNA ligase D.

scientific article

Parallel analysis of ribonucleotide-dependent deletions produced by yeast Top1 in vitro and in vivo

scientific article published on June 2016

Phospho-site mutants of the RNA Polymerase II C-terminal domain alter subtelomeric gene expression and chromatin modification state in fission yeast

scientific article published on 08 July 2016

Poly(A) site choice and Pol2 CTD Serine-5 status govern lncRNA control of phosphate-responsive tgp1 gene expression in fission yeast

scientific article published on 9 November 2017

Portability and fidelity of RNA-repair systems

scholarly article

Poxvirus mRNA cap methyltransferase. Bypass of the requirement for the stimulatory subunit by mutations in the catalytic subunit and evidence for intersubunit allostery

scientific article published on 16 May 2006

Punctuation and syntax of the RNA polymerase II CTD code in fission yeast

scientific article published on 15 October 2012

RNA 3'-phosphate cyclase (RtcA) catalyzes ligase-like adenylylation of DNA and RNA 5'-monophosphate ends ⬇️

scientific article published on November 22, 2010

RNA ligase RtcB splices 3′-phosphate and 5′-OH ends via covalent RtcB-(histidinyl)-GMP and polynucleotide-(3′)pp(5′)G intermediates ⬇️

scientific article published on April 2, 2012

RNA polymerase II CTD phospho-sites Ser5 and Ser7 govern phosphate homeostasis in fission yeast

scientific article

RNA repair: an antidote to cytotoxic eukaryal RNA damage

scientific article published on July 2008

RNA substrate specificity and structure-guided mutational analysis of bacteriophage T4 RNA ligase 2.

scientific article published on 13 April 2004

RecF and RecR Play Critical Roles in the Homologous Recombination and Single-Strand Annealing Pathways of Mycobacteria

scientific article published on 20 July 2015

Remote phosphate contacts trigger assembly of the active site of DNA topoisomerase IB.

scientific article

Reprogramming the tRNA-splicing activity of a bacterial RNA repair enzyme

scientific article published on 8 May 2007

Rewriting the rules for end joining via enzymatic splicing of DNA 3'-PO4 and 5'-OH ends

scientific article

Role of nucleotidyltransferase motifs I, III and IV in the catalysis of phosphodiester bond formation by Chlorella virus DNA ligase

scientific article published on February 2002

RtcB is the RNA ligase component of an Escherichia coli RNA repair operon

scientific article

RtcB, a novel RNA ligase, can catalyze tRNA splicing and HAC1 mRNA splicing in vivo

scientific article

Schizosaccharomyces pombe carboxyl-terminal domain (CTD) phosphatase Fcp1: distributive mechanism, minimal CTD substrate, and active site mapping

scientific article published on 29 December 2003

Separable functions of the fission yeast Spt5 carboxyl-terminal domain (CTD) in capping enzyme binding and transcription elongation overlap with those of the RNA polymerase II CTD

scientific article

Sequence-specific 1H N, 13C, and 15N backbone resonance assignments of the 34 kDa Paramecium bursaria Chlorella virus 1 (PBCV1) DNA ligase

scientific article

Sequence-specific 1H, 13C and 15N assignments of the phosphoesterase (PE) domain of Pseudomonas aeruginosa DNA ligase D (LigD).

scientific article published on 7 January 2011

Sinefungin resistance of Saccharomyces cerevisiae arising from Sam3 mutations that inactivate the AdoMet transporter or from increased expression of AdoMet synthase plus mRNA cap guanine-N7 methyltransferase

scientific article

Site-specific DNA transesterification by vaccinia topoisomerase: effects of benzo[alpha]pyrene-dA, 8-oxoguanine, 8-oxoadenine and 2-aminopurine modifications

scientific article published on 8 August 2003

Solution NMR studies of Chlorella virus DNA ligase-adenylate

scientific article

Solution structure and DNA-binding properties of the phosphoesterase domain of DNA ligase D ⬇️

scientific article published on November 13, 2011

Specificity and mechanism of RNA cap guanine-N2 methyltransferase (Tgs1).

scientific article published on 7 December 2004

Structural Insights to How Mammalian Capping Enzyme Reads the CTD Code ⬇️

scientific article published on June 16, 2011

Structural and Biochemical Analysis of the Phosphate Donor Specificity of the Polynucleotide Kinase Component of the Bacterial Pnkp•Hen1 RNA Repair System

scientific article

Structural basis for recognition of intron branchpoint RNA by yeast Msl5 and selective effects of interfacial mutations on splicing of yeast pre-mRNAs

scientific article

Structural basis for the GTP specificity of the RNA kinase domain of fungal tRNA ligase

scientific article published on 20 November 2017

Structural insights to the metal specificity of an archaeal member of the LigD 3'-phosphoesterase DNA repair enzyme family

scientific article

Structure and mechanism of E. coli RNA 2',3'-cyclic phosphodiesterase

scientific article

Structure and mechanism of RNA ligase

scientific article

Structure and mechanism of T4 polynucleotide kinase: an RNA repair enzyme

scientific article

Structure and mechanism of the 2',3' phosphatase component of the bacterial Pnkp-Hen1 RNA repair system

scientific article

Structure and mechanism of the polynucleotide kinase component of the bacterial Pnkp-Hen1 RNA repair system

scientific article

Structure and two-metal mechanism of a eukaryal nick-sealing RNA ligase

scientific article

Structure of a CRISPR-associated protein Cas2 fromDesulfovibrio vulgaris

scientific article

Structure of an mRNA capping enzyme bound to the phosphorylated carboxy-terminal domain of RNA polymerase II

scientific article

Structure of bacterial LigD 3'-phosphoesterase unveils a DNA repair superfamily

scientific article

Structure of mycobacterial 3'-to-5' RNA:DNA helicase Lhr bound to a ssDNA tracking strand highlights distinctive features of a novel family of bacterial helicases

scientific article published on 20 November 2017

Structure of tRNA splicing enzyme Tpt1 illuminates the mechanism of RNA 2'-PO recognition and ADP-ribosylation

scientific article published in Nature Communications

Structure, Mechanism, and Specificity of a Eukaryal tRNA Restriction Enzyme Involved in Self-Nonself Discrimination

scientific article

Structure-Function Analysis of Trypanosoma brucei RNA Triphosphatase and Evidence for a Two-metal Mechanism ⬇️

scientific article published on December 19, 2003

Structure-Function Analysis of the OB and Latch Domains of Chlorella Virus DNA Ligase ⬇️

scientific article published on April 28, 2011

Structure-activity relationships in Kluyveromyces lactis gamma-toxin, a eukaryal tRNA anticodon nuclease

scientific article published on 21 April 2009

Structure-activity relationships in human RNA 3'-phosphate cyclase

scientific article published on 18 August 2009

Structure-function analysis and genetic interactions of the Luc7 subunit of the Saccharomyces cerevisiae U1 snRNP.

scientific article published on 27 June 2016

Structure-function analysis and genetic interactions of the SmG, SmE, and SmF subunits of the yeast Sm protein ring

scientific article published on 14 July 2016

Structure-function analysis and genetic interactions of the Yhc1, SmD3, SmB, and Snp1 subunits of yeast U1 snRNP and genetic interactions of SmD3 with U2 snRNP subunit Lea1.

scientific article published on 20 April 2015

Structure-function analysis of Plasmodium RNA triphosphatase and description of a triphosphate tunnel metalloenzyme superfamily that includes Cet1-like RNA triphosphatases and CYTH proteins

scientific article

Structure-function analysis of T4 RNA ligase 2.

scientific article published on 27 February 2003

Structure-function analysis of the 5' end of yeast U1 snRNA highlights genetic interactions with the Msl5*Mud2 branchpoint-binding complex and other spliceosome assembly factors

scientific article published on 10 June 2013

Structure-function analysis of the Yhc1 subunit of yeast U1 snRNP and genetic interactions of Yhc1 with Mud2, Nam8, Mud1, Tgs1, U1 snRNA, SmD3 and Prp28.

scientific article published on 04 February 2014

Structure-function analysis of the kinase-CPD domain of yeast tRNA ligase (Trl1) and requirements for complementation of tRNA splicing by a plant Trl1 homolog

scientific article

Structure-function analysis of the yeast NAD+-dependent tRNA 2'-phosphotransferase Tpt1

scientific article

Structure-function analysis of vaccinia virus mRNA cap (guanine-N7) methyltransferase

scientific article published on 6 February 2008

Structure-function analysis of yeast RNA debranching enzyme (Dbr1), a manganese-dependent phosphodiesterase

scientific article

Structure-function analysis of yeast tRNA ligase

scientific article published on June 2005

Structure-guided Mutational Analysis of the Nucleotidyltransferase Domain of Escherichia coli DNA Ligase (LigA).

scientific article

Structure-guided mutational analysis of T4 RNA ligase 1.

scientific article

Structure-guided mutational analysis of the OB, HhH, and BRCT domains of Escherichia coli DNA ligase

scientific article

Structure-guided mutational analysis of the nucleotidyltransferase domain of Escherichia coli NAD+-dependent DNA ligase (LigA).

scientific article published on 24 January 2005

Structures and activities of archaeal members of the LigD 3'-phosphoesterase DNA repair enzyme superfamily

scientific article

Structures of RNA 3'-phosphate cyclase bound to ATP reveal the mechanism of nucleotidyl transfer and metal-assisted catalysis

scientific article

Structures of bacterial polynucleotide kinase in a michaelis complex with nucleoside triphosphate (NTP)-Mg2+ and 5'-OH RNA and a mixed substrate-product complex with NTP-Mg2+ and a 5'-phosphorylated oligonucleotide

scientific article published on 29 September 2014

Structure–function analysis and genetic interactions of the yeast branchpoint binding protein Msl5 ⬇️

scientific article published on January 28, 2012

Structure–function analysis of the 3′ phosphatase component of T4 polynucleotide kinase/phosphatase

scientific article

Structure–function relations in the NTPase domain of the antiviral tRNA ribotoxin Escherichia coli PrrC ⬇️

scientific article published on March 2, 2012

Substrate specificity and mutational analysis of Kluyveromyces lactis gamma-toxin, a eukaryal tRNA anticodon nuclease

scientific article published on 24 May 2011

Substrate specificity and structure-function analysis of the 3'-phosphoesterase component of the bacterial NHEJ protein, DNA ligase D.

scientific article published on 14 March 2006

Tat stimulates cotranscriptional capping of HIV mRNA.

scientific article

The C-terminal domain of T4 RNA ligase 1 confers specificity for tRNA repair

scientific article published on 21 June 2007

The DNA Repair Repertoire of Mycobacterium smegmatis FenA Includes the Incision of DNA 5' Flaps and the Removal of 5' Adenylylated Products of Aborted Nick Ligation

scientific article published on 19 June 2017

The PAF complex and Prf1/Rtf1 delineate distinct Cdk9-dependent pathways regulating transcription elongation in fission yeast

scientific article

The Structure of Fcp1, an Essential RNA Polymerase II CTD Phosphatase

scientific article

The adenylyltransferase domain of bacterial Pnkp defines a unique RNA ligase family

scientific article

The domain order of mammalian capping enzyme can be inverted and baculovirus phosphatase can function in cap formation in vivo

scientific article

The pathways and outcomes of mycobacterial NHEJ depend on the structure of the broken DNA ends

scientific article

The sequential 2',3'-cyclic phosphodiesterase and 3'-phosphate/5'-OH ligation steps of the RtcB RNA splicing pathway are GTP-dependent ⬇️

scientific article published on June 22, 2012

Transcription of lncRNA prt, clustered prt RNA sites for Mmi1 binding, and RNA polymerase II CTD phospho-sites govern the repression of pho1 gene expression under phosphate-replete conditions in fission yeast

scientific article published on 10 May 2016

Two Routes to Genetic Suppression of RNA Trimethylguanosine Cap Deficiency via C-Terminal Truncation of U1 snRNP Subunit Snp1 or Overexpression of RNA Polymerase Subunit Rpo26

scientific article published on 24 April 2015

Two-metal versus one-metal mechanisms of lysine adenylylation by ATP-dependent and NAD+-dependent polynucleotide ligases

scientific article

Will the circle be unbroken: specific mutations in the yeast Sm protein ring expose a requirement for assembly factor Brr1, a homolog of Gemin2.

scientific article published on 14 December 2016

Yeast-based genetic system for functional analysis of poxvirus mRNA cap methyltransferase

scientific article published on July 2003

Yeast-like mRNA capping apparatus in Giardia lamblia

scientific article published on 19 November 2004

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