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List of works by Kevin A. Janes

A High-throughput Assay for Phosphoprotein-specific Phosphatase Activity in Cellular Extracts ⬇️

scientific article published on December 11, 2012

A biological approach to computational models of proteomic networks

scientific article

A cell non-autonomous mechanism of yeast chronological aging regulated by caloric restriction and one-carbon metabolism

scientific article published on 26 November 2020

A compendium of signals and responses triggered by prodeath and prosurvival cytokines

scientific article published on 18 July 2005

A high-throughput quantitative multiplex kinase assay for monitoring information flow in signaling networks: application to sepsis-apoptosis

scientific article published on 26 June 2003

A multiplexed homogeneous fluorescence-based assay for protein kinase activity in cell lysates

scientific article

A systems model of signaling identifies a molecular basis set for cytokine-induced apoptosis

scientific article published in December 2005

A time- and matrix-dependent TGFBR3-JUND-KRT5 regulatory circuit in single breast epithelial cells and basal-like premalignancies

scientific article

Adenoviral vector saturates Akt pro-survival signaling and blocks insulin-mediated rescue of tumor necrosis-factor-induced apoptosis

scientific article published on 29 August 2006

An ERK-p38 Subnetwork Coordinates Host Cell Apoptosis and Necrosis during Coxsackievirus B3 Infection ⬇️

scientific article published on January 16, 2013

An analysis of critical factors for quantitative immunoblotting

scientific article

An engineering design approach to systems biology

scientific article

An ultrasensitive fiveplex activity assay for cellular kinases

scientific article published on 19 December 2019

Applying computational modeling to drug discovery and development

scientific article published on September 2006

Astrocytic trans-Differentiation Completes a Multicellular Paracrine Feedback Loop Required for Medulloblastoma Tumor Growth

scientific article published on 23 January 2020

Automated brightfield morphometry of 3D organoid populations by OrganoSeg

scientific article

Bringing systems biology to cancer, immunology and infectious disease

scientific article

CIRCOAST: A Statistical Hypothesis Test for Cellular Colocalization with Network Structures

CIRCOAST: a statistical hypothesis test for cellular colocalization with network structures

scientific article published in February 2019

Cell-to-Cell Transcript Variability: Seeing Signal in the Noise

scientific article

Chitosan nanoparticles as delivery systems for doxorubicin

scientific article published on 01 June 2001

Chitosan-DNA nanoparticles as gene carriers: synthesis, characterization and transfection efficiency

scientific article

Common effector processing mediates cell-specific responses to stimuli

scientific article

Computational Models of Reactive Oxygen Species as Metabolic Byproducts and Signal-Transduction Modulators

scientific article

Corrigendum to: "Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven Cancers" [EBioMedicine 8 (2016) 117-131].

scientific article published on 31 October 2017

Cue-signal-response analysis of TNF-induced apoptosis by partial least squares regression of dynamic multivariate data

scientific article published in January 2004

Cytokine-induced signaling networks prioritize dynamic range over signal strength

scientific article published on October 2008

Data-driven modelling of signal-transduction networks

scientific article

Distinct MUNC lncRNA structural domains regulate transcription of different promyogenic factors

scientific article published on 01 February 2022

Enteral versus parenteral nutrition in cancer patients: evidences and controversies

scientific article

Fragile epitopes-Antibody's guess is as good as yours

scientific article published on 28 January 2020

Fragmentation of Small-Cell Lung Cancer Regulatory States in Heterotypic Microenvironments

publication published on 02 February 2021

Identifying single-cell molecular programs by stochastic profiling

scientific article

In situ 10-cell RNA sequencing in tissue and tumor biopsy samples

scientific article published on 20 March 2019

Intersection of FOXO- and RUNX1-mediated gene expression programs in single breast epithelial cells during morphogenesis and tumor progression ⬇️

scientific article published on August 22, 2011

Low molecular weight chitosan nanoparticles as new carriers for nasal vaccine delivery in mice

scientific article published in January 2004

Modeling the complete kinetics of coxsackievirus B3 reveals human determinants of host-cell feedback

scientific article published on 18 March 2021

Modeling the latent dimensions of multivariate signaling datasets

scientific article

Models of signalling networks – what cell biologists can gain from them and give to them ⬇️

scientific article published on May 1, 2013

Multiscale Models of Cell Signaling ⬇️

scientific article published on April 3, 2012

Network Architecture Predisposes an Enzyme to Either Pharmacologic or Genetic Targeting

scientific article

Non-genetic heterogeneity caused by differential single-cell adhesion

scientific article published on 23 June 2014

Normal morphogenesis of epithelial tissues and progression of epithelial tumors

scientific article

Pairwise network mechanisms in the host signaling response to coxsackievirus B3 infection ⬇️

scientific article published on September 10, 2010

Pan-Cancer Drivers Are Recurrent Transcriptional Regulatory Heterogeneities in Early-Stage Luminal Breast Cancer

publication published on 02 February 2021

Parameterizing cell-to-cell regulatory heterogeneities via stochastic transcriptional profiles

scientific article

Paring down signaling complexity

scientific article published on July 2010

Polysaccharide colloidal particles as delivery systems for macromolecules

scientific article

Premalignant Oligodendrocyte Precursor Cells Stall in a Heterogeneous State of Replication Stress Prior to Gliomagenesis

publication published on 02 February 2021

Profiling Subcellular Protein Phosphatase Responses to Coxsackievirus B3 Infection of Cardiomyocytes

scientific article

RUNX1 and its understudied role in breast cancer ⬇️

scientific article published on October 15, 2011

Robust latent-variable interpretation of in vivo regression models by nested resampling

scientific article published on 23 December 2019

Science Signaling Podcast for 7 June 2016: Modeling signal integration

scientific article

Simultaneous Profiling of 194 Distinct Receptor Transcripts in Human Cells ⬇️

scientific article published on August 6, 2013

Single-cell states versus single-cell atlases - two classes of heterogeneity that differ in meaning and method

scientific article

Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven Cancers

scientific article

Sporadic activation of an oxidative stress-dependent NRF2-p53 signaling network in breast epithelial spheroids and premalignancies

scientific article published on 14 April 2020

Stochastic profiling of transcriptional regulatory heterogeneities in tissues, tumors and cultured cells ⬇️

scientific article published on January 10, 2013

TNF-insulin crosstalk at the transcription factor GATA6 is revealed by a model that links signaling and transcriptomic data tensors

scientific article

The receptor tyrosine kinase Ror is required for dendrite regeneration in Drosophila neurons

scientific article published on 12 March 2020

The response of human epithelial cells to TNF involves an inducible autocrine cascade

scientific article published on March 2006

Tumor-Suppressor Inactivation of GDF11 Occurs by Precursor Sequestration in Triple-Negative Breast Cancer

scientific article published in November 2017

When microarrays Met epidermal-cell migration

scientific article published on July 2008

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