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List of works by Krzysztof Mrózek

11q23 balanced chromosome aberrations in treatment-related myelodysplastic syndromes and acute leukemia: report from an international workshop

scientific article published in April 2002

A genome-wide association study of susceptibility to acute lymphoblastic leukemia in adolescents and young adults

scientific article

A pediatric regimen for older adolescents and young adults with acute lymphoblastic leukemia: results of CALGB 10403

scientific article published on 18 January 2019

ASXL1 mutations identify a high-risk subgroup of older patients with primary cytogenetically normal AML within the ELN Favorable genetic category

scientific article

Abnormal Cytogenetics at Date of Morphologic Complete Remission Predicts Short Overall and Disease-Free Survival, and Higher Relapse Rate in Adult Acute Myeloid Leukemia: Results From Cancer and Leukemia Group B Study 8461

article

Acquired copy number alterations in adult acute myeloid leukemia genomes

scholarly article

Acute myeloid leukemia with adverse cytogenetic risk ⬇️

scientific article published on August 1, 2012

Acute myeloid leukemia with complex karyotypes and abnormal chromosome 21: Amplification discloses overexpression of APP, ETS2, and ERG genes

scholarly article

Additional cytogenetic abnormalities in adults with Philadelphia chromosome-positive acute lymphoblastic leukaemia: a study of the Cancer and Leukaemia Group B.

scientific article

Additional gene mutations may refine the 2017 European LeukemiaNet classification in adult patients with de novo acute myeloid leukemia aged <60 years

scientific article published on 27 May 2020

Adult de novo acute myeloid leukemia with t(6;11)(q27;q23): results from Cancer and Leukemia Group B Study 8461 and review of the literature

scientific article published in September 2004

Advances in molecular genetics and treatment of core-binding factor acute myeloid leukemia

scientific article

Adverse prognostic significance of KIT mutations in adult acute myeloid leukemia with inv(16) and t(8;21): a Cancer and Leukemia Group B Study

scientific article

Age-related prognostic impact of different types of DNMT3A mutations in adults with primary cytogenetically normal acute myeloid leukemia

scientific article

Allogeneic hematopoietic cell transplantation compared to chemotherapy consolidation in older acute myeloid leukemia (AML) patients 60-75 years in first complete remission (CR1): an alliance (A151509), SWOG, ECOG-ACRIN, and CIBMTR study

scientific article published on 09 May 2019

Author Correction: The long non-coding RNA HOXB-AS3 regulates ribosomal RNA transcription in NPM1-mutated acute myeloid leukemia

scientific article published on 29 July 2020

BAALC and ERG expression levels are associated with outcome and distinct gene and microRNA expression profiles in older patients with de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study

scientific article

COLIA1-PDGFB gene fusion in dermatofibrosarcoma protuberans. molecular analysis of a case with an unusual large marker containing sequences from chromosomes 7, 8, 17, 21, and 22

scientific article published on 01 June 2002

CREB-binding protein regulates apoptosis and growth of HMECs grown in reconstituted ECM via laminin-5.

scientific article published on 11 October 2005

Cancer and leukemia group B leukemia correlative science committee: major accomplishments and future directions

scientific article

Central review of cytogenetics is necessary for cooperative group correlative and clinical studies of adult acute leukemia: the Cancer and Leukemia Group B experience

scientific article published on August 2008

Chromosome aberrations, gene mutations and expression changes, and prognosis in adult acute myeloid leukemia

scientific article published on January 2006

Chromosome abnormalities at onset of complete remission are associated with worse outcome in patients with acute myeloid leukemia and an abnormal karyotype at diagnosis: CALGB 8461 (Alliance).

scientific article

Clinical and functional significance of circular RNAs in cytogenetically normal AML

scientific article published on 01 January 2020

Clinical and molecular characterization of patients with acute myeloid leukemia and sole trisomies of chromosomes 4, 8, 11, 13 or 21

scientific article published on 28 August 2019

Clinical outcome and gene- and microRNA-expression profiling according to the Wilms tumor 1 (WT1) single nucleotide polymorphism rs16754 in adult de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study

scientific article

Clinical outcome of de novo acute myeloid leukaemia patients with normal cytogenetics is affected by molecular genetic alterations: a concise review

scientific article

Clinical relevance of mutations and gene-expression changes in adult acute myeloid leukemia with normal cytogenetics: are we ready for a prognostically prioritized molecular classification?

scientific article published on 7 September 2006

Clinical role of microRNAs in cytogenetically normal acute myeloid leukemia: miR-155 upregulation independently identifies high-risk patients

scientific article published on 06 May 2013

Clinical significance of the most common chromosome translocations in adult acute myeloid leukemia

scientific article published in January 2008

Combination of dasatinib with chemotherapy in previously untreated core binding factor acute myeloid leukemia: CALGB 10801

scientific article published on 01 February 2020

Comparison of reduced-intensity hematopoietic cell transplantation with chemotherapy in patients age 60-70 years with acute myelogenous leukemia in first remission

scientific article

Complex karyotype in de novo acute myeloid leukemia: typical and atypical subtypes differ molecularly and clinically

scientific article published on 08 February 2019

Comprehensive cytogenetic and molecular genetic characterization of the TI-1 acute myeloid leukemia cell line reveals cross-contamination with K-562 cell line

scientific article published in March 2002

Core-binding factor acute myeloid leukemia with inv(16): Older age and high white blood cell count are risk factors for treatment failure

scientific article published on 14 September 2020

Core-binding factor acute myeloid leukemia with t(8;21): Risk factors and a novel scoring system (I-CBFit)

Cytogenetic and molecular findings in 75 clear cell renal cell carcinomas

scientific article published on 01 May 2005

Cytogenetic, molecular genetic, and clinical characteristics of acute myeloid leukemia with a complex karyotype

scientific article published on August 2008

Cytogenetics and molecular genetics of acute lymphoblastic leukemia

scientific article published on 01 October 2009

Cytogenetics in acute leukemia

scientific article

Deregulation of DUX4 and ERG in acute lymphoblastic leukemia

scientific article published on 24 October 2016

Diagnostic and Prognostic Value of Cytogenetics in Acute Myeloid Leukemia ⬇️

scientific article published on December 1, 2011

Discovery of clinically relevant fusions in pediatric cancer

scientific article published on 04 December 2021

Dose intensification of daunorubicin and cytarabine during treatment of adult acute lymphoblastic leukemia: results of Cancer and Leukemia Group B Study 19802.

scientific article

Epigenetics meets genetics in acute myeloid leukemia: clinical impact of a novel seven-gene score

scientific article published on 30 December 2013

Evidence for Phenotypic Plasticity in Aggressive Triple-Negative Breast Cancer: Human Biology Is Recapitulated by a Novel Model System ⬇️

scientific article published on September 25, 2012

Expression analyses identify MLL as a prominent target of 11q23 amplification and support an etiologic role for MLL gain of function in myeloid malignancies

scientific article published on 28 August 2003

Expression and functional relevance of long non-coding RNAs in acute myeloid leukemia stem cells

scientific article published on 11 March 2019

Expression and prognostic impact of lncRNAs in acute myeloid leukemia

scientific article

FLT3 D835/I836 mutations are associated with poor disease-free survival and a distinct gene-expression signature among younger adults with de novo cytogenetically normal acute myeloid leukemia lacking FLT3 internal tandem duplications

scientific article

FLT3 internal tandem duplication associates with adverse outcome and gene- and microRNA-expression signatures in patients 60 years of age or older with primary cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study

scientific article

Favorable prognostic impact of NPM1 mutations in older patients with cytogenetically normal de novo acute myeloid leukemia and associated gene- and microRNA-expression signatures: a Cancer and Leukemia Group B study

scientific article

GAS6 expression identifies high-risk adult AML patients: potential implications for therapy

scientific article

Genetic Characterization and Prognostic Relevance of Acquired Uniparental Disomies in Cytogenetically Normal Acute Myeloid Leukemia

scientific article published on 02 August 2019

Genome-wide association study identifies an acute myeloid leukemia susceptibility locus near BICRA

scientific article published on 05 October 2018

Genomic analyses identify recurrent MEF2D fusions in acute lymphoblastic leukaemia

scientific article

High BAALC expression associates with other molecular prognostic markers, poor outcome, and a distinct gene-expression signature in cytogenetically normal patients younger than 60 years with acute myeloid leukemia: a Cancer and Leukemia Group B (CAL

scientific article published on 31 March 2008

High Expression Levels of theETS-Related Gene,ERG, Predict Adverse Outcome and Improve Molecular Risk-Based Classification of Cytogenetically Normal Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study

article

High Frequency and Poor Outcome of Philadelphia Chromosome-Like Acute Lymphoblastic Leukemia in Adults

scientific article published on 21 November 2016

IDH1 and IDH2 gene mutations identify novel molecular subsets within de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study

scientific article

Implementation of standardized variant-calling nomenclature in the age of next-generation sequencing: where do we stand?

scientific article published on 24 January 2019

In rare acute myeloid leukemia patients harboring both RUNX1 and NPM1 mutations, RUNX1 mutations are unusual in structure and present in the germline

scientific article published on 10 June 2013

Independent confirmation of a prognostic gene-expression signature in adult acute myeloid leukemia with a normal karyotype: a Cancer and Leukemia Group B study

scientific article published on 2 May 2006

Influence of new molecular prognostic markers in patients with karyotypically normal acute myeloid leukemia: recent advances

scientific article published on March 2007

Intensive induction is effective in selected octogenarian acute myeloid leukemia patients: prognostic significance of karyotype and selected molecular markers used in the European LeukemiaNet classification

scientific article published on 04 October 2013

Isolated trisomy of chromosomes 8, 11, 13 and 21 is an adverse prognostic factor in adults with de novo acute myeloid leukemia: results from Cancer and Leukemia Group B 8461.

scientific article published in November 2002

Lenalidomide-mediated enhanced translation of C/EBPα-p30 protein up-regulates expression of the antileukemic microRNA-181a in acute myeloid leukemia

scientific article published on 25 October 2012

Long-term disease-free survivors with cytogenetically normal acute myeloid leukemia and MLL partial tandem duplication: a Cancer and Leukemia Group B study

scientific article published on 6 March 2007

Low expression of MN1 associates with better treatment response in older patients with de novo cytogenetically normal acute myeloid leukemia

scientific article published on 9 August 2011

Low-dose interleukin-2 immunotherapy does not improve outcome of patients age 60 years and older with acute myeloid leukemia in first complete remission: Cancer and Leukemia Group B Study 9720.

scientific article

MicroRNA expression in acute myeloid leukemia

scientific article published on April 2009

MicroRNA expression in cytogenetically normal acute myeloid leukemia

scientific article

MicroRNA expression profiling in acute myeloid and chronic lymphocytic leukaemias

scientific article published on June 2009

Molecular cytogenetic characterization of the KG‐1 and KG‐1a acute myeloid leukemia cell lines by use of spectral karyotyping and fluorescence in situ hybridization ⬇️

scientific article published on November 1, 2003

Molecular heterogeneity and prognostic biomarkers in adults with acute myeloid leukemia and normal cytogenetics

scientific article

Molecular signatures in acute myeloid leukemia.

scientific article

Mutation patterns identify adult patients with de novo acute myeloid leukemia aged 60 years or older who respond favorably to standard chemotherapy: an analysis of Alliance studies

scientific article published on 25 February 2018

Mutational Landscape and Gene Expression Patterns in Adult Acute Myeloid Leukemias with Monosomy 7 as a Sole Abnormality

scientific article published on 26 October 2016

Mutational landscape and clinical outcome of patients with de novo acute myeloid leukemia and rearrangements involving 11q23/KMT2A

scientific article published on 05 October 2020

Mutations associated with a 17-gene leukemia stem cell score and the score's prognostic relevance in the context of the European LeukemiaNet classification of acute myeloid leukemia

scientific article published on 14 August 2019

Mutations of the Wilms tumor 1 gene (WT1) in older patients with primary cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study

scientific article

NF1 mutations are recurrent in adult acute myeloid leukemia and confer poor outcome

New recurrent balanced translocations in acute myeloid leukemia and myelodysplastic syndromes: Cancer and leukemia group B 8461 ⬇️

scientific article published on December 10, 2012

Outcome of induction and postremission therapy in younger adults with acute myeloid leukemia with normal karyotype: a cancer and leukemia group B study

scientific article published on 8 November 2004

Overexpression of the ETS-related gene, ERG, predicts a worse outcome in acute myeloid leukemia with normal karyotype: a Cancer and Leukemia Group B study

scientific article

PAX5-driven subtypes of B-progenitor acute lymphoblastic leukemia

scientific article published on 14 January 2019

Patients with acute myeloid leukemia and RAS mutations benefit most from postremission high-dose cytarabine: a Cancer and Leukemia Group B study

scientific article

Persistence of DNMT3A R882 mutations during remission does not adversely affect outcomes of patients with acute myeloid leukaemia

scientific article published on August 2016

Poor Survival and Differential Impact of Genetic Features of Black Patients with Acute Myeloid Leukemia

scientific article published on 04 December 2020

Pretreatment cytogenetic abnormalities are predictive of induction success, cumulative incidence of relapse, and overall survival in adult patients with de novo acute myeloid leukemia: results from Cancer and Leukemia Group B (CALGB 8461)

scientific article (publication date: 15 December 2002)

Pretreatment cytogenetics add to other prognostic factors predicting complete remission and long-term outcome in patients 60 years of age or older with acute myeloid leukemia: results from Cancer and Leukemia Group B 8461.

scientific article published on 7 March 2006

Prognostic and Biologic Relevance of Clinically Applicable Long Noncoding RNA Profiling in Older Patients with Cytogenetically Normal Acute Myeloid Leukemia

scientific article published on 04 June 2019

Prognostic and biologic significance of long non-coding RNA profiling in younger adults with cytogenetically normal acute myeloid leukemia

scientific article published on 04 May 2017

Prognostic and biological significance of the proangiogenic factor EGFL7 in acute myeloid leukemia

scientific article published on 22 May 2017

Prognostic factors and outcome of core binding factor acute myeloid leukemia patients with t(8;21) differ from those of patients with inv(16): a Cancer and Leukemia Group B study

scientific article published in August 2005

Prognostic gene mutations and distinct gene- and microRNA-expression signatures in acute myeloid leukemia with a sole trisomy 8.

scientific article

Prognostic impact of the CD34+/CD38- cell burden in patients with acute myeloid leukemia receiving allogeneic stem cell transplantation

scientific article published on 30 January 2017

Prognostic importance of MN1 transcript levels, and biologic insights from MN1-associated gene and microRNA expression signatures in cytogenetically normal acute myeloid leukemia: a cancer and leukemia group B study

scientific article

Prognostic significance of additional cytogenetic abnormalities in newly diagnosed patients with Philadelphia chromosome-positive chronic myelogenous leukemia treated with interferon-alpha: a Cancer and Leukemia Group B study.

scientific article published in July 2004

Prognostic significance of expression of a single microRNA, miR-181a, in cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study

scientific article

Prognostic significance of the European LeukemiaNet standardized system for reporting cytogenetic and molecular alterations in adults with acute myeloid leukemia

scientific article

Prognostic significance of, and gene and microRNA expression signatures associated with, CEBPA mutations in cytogenetically normal acute myeloid leukemia with high-risk molecular features: a Cancer and Leukemia Group B Study

scientific article published on 22 September 2008

Publisher Correction: The long non-coding RNA HOXB-AS3 regulates ribosomal RNA transcription in NPM1-mutated acute myeloid leukemia

scientific article published on 07 January 2020

RUNX1 mutations are associated with poor outcome in younger and older patients with cytogenetically normal acute myeloid leukemia and with distinct gene and MicroRNA expression signatures

scientific article

Randomized trial of 10 days of decitabine ± bortezomib in untreated older patients with AML: CALGB 11002 (Alliance)

scholarly article published 26 December 2018

Rare t(X;14)(q28;q32) translocation reveals link between MTCP1 and chronic lymphocytic leukemia

scientific article published on 03 November 2021

Repetitive cycles of high-dose cytarabine benefit patients with acute myeloid leukemia and inv(16)(p13q22) or t(16;16)(p13;q22): results from CALGB 8461.

scientific article published in March 2004

Reply to K. Orendi et al ⬇️

scientific article published on June 20, 2013

Response: Conflicting data on the prognostic significance of FLT3-TKD mutations in cytogenetically normal acute myeloid leukemia (CN-AML) might be related to many factors, including techniques used to detect FLT3-TKD, differences in patient populati

scientific article published in July 2008

SPARC promotes leukemic cell growth and predicts acute myeloid leukemia outcome

scientific article published on 03 March 2014

Spectral karyotyping in patients with acute myeloid leukemia and a complex karyotype shows hidden aberrations, including recurrent overrepresentation of 21q, 11q, and 22q.

scientific article published on June 2002

TET2 mutations improve the new European LeukemiaNet risk classification of acute myeloid leukemia: a Cancer and Leukemia Group B study

scientific article

Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia

scientific article

Ten-year outcome of patients with acute myeloid leukemia not treated with allogeneic transplantation in first complete remission

scholarly article published 10 July 2018

The long non-coding RNA HOXB-AS3 regulates ribosomal RNA transcription in NPM1-mutated acute myeloid leukemia

scientific article published on 25 November 2019

Unique balanced chromosome abnormalities in treatment-related myelodysplastic syndromes and acute myeloid leukemia: report from an international workshop

scientific article published in April 2002

Wilms' tumor 1 gene mutations independently predict poor outcome in adults with cytogenetically normal acute myeloid leukemia: a cancer and leukemia group B study

scientific article

inv(16)/t(16;16) acute myeloid leukemia with non-type A CBFB-MYH11 fusions associate with distinct clinical and genetic features and lack KIT mutations

scientific article published on 16 November 2012

miR-3151 Interplays With its Host Gene BAALC and Independently Impacts on Outcome of Older Patients With Cytogenetically Normal Acute Myeloid Leukemia by Direct Deregulation of TP53

article

miR-3151 interplays with its host gene BAALC and independently affects outcome of patients with cytogenetically normal acute myeloid leukemia

scientific article

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