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List of works by Emanuela Ottaviani

A case report of acute myeloid leukemia and neurofibromatosis 1.

scientific article published in June 2013

A polymorphism in the chromosome 9p21 ANRIL locus is associated to Philadelphia positive acute lymphoblastic leukemia

scientific article

Assessment of the interlaboratory variability and robustness of JAK2V617F mutation assays: A study involving a consortium of 19 Italian laboratories

scientific article published on 6 March 2017

Association of 3q21q26 syndrome with different RPN1/EVI1 fusion transcripts

scientific article

Association of essential thrombocythemia and non-Hodgkin lymphoma: a single-centre experience.

scientific article published in March 2009

B-cell acute lymphoblastic leukemia as evolution of a 8p11 myeloproliferative syndrome with t(8;22)(p11;q11) and BCR-FGFR1 fusion gene.

scientific article

CDKN2A/B alterations impair prognosis in adult BCR-ABL1-positive acute lymphoblastic leukemia patients.

scientific article

Chromothripsis in acute myeloid leukemia: biological features and impact on survival

scientific article published on 23 February 2018

Clonal eosinophils are a morphologic hallmark of ETV6/ABL1 positive acute myeloid leukemia

scientific article published in August 2002

Comparison between patients with Philadelphia-positive chronic phase chronic myeloid leukemia who obtained a complete cytogenetic response within 1 year of imatinib therapy and those who achieved such a response after 12 months of treatment

scientific article published in January 2006

Comparison of JAK2(V617F) -positive essential thrombocythaemia and early primary myelofibrosis: The impact of mutation burden and histology

scientific article

Complex chromosomal rearrangements leading to MECOM overexpression are recurrent in myeloid malignancies with various 3q abnormalities

Complex variant Philadelphia translocations involving the short arm of chromosome 6 in chronic myeloid leukemia.

scientific article published on February 2002

Crucial factors of the inflammatory microenvironment (IL-1β/TNF-α/TIMP-1) promote the maintenance of the malignant hemopoietic clone of myelofibrosis: an in vitro study

scientific article

Cryptic translocation of PML/RARA on 17q. A rare event in acute promyelocytic leukemia

scientific article

Cyclin D1 overexpression is a favorable prognostic variable for newly diagnosed multiple myeloma patients treated with high-dose chemotherapy and single or double autologous transplantation.

scientific article

Detection of serine 473 phosphorylated Akt in acute myeloid leukaemia blasts by flow cytometry

scientific article

Diabetes insipidus as first manifestation of acute myeloid leukaemia with EVI-1-positive, 3q21q26 syndrome and T cell-line antigen expression: what is the EVI-1 gene role?

scientific article published on August 2002

Efficacy of Azacitidine in the treatment of adult patients aged 65 years or older with AML.

scientific article published on 10 November 2016

Epigenetically induced ectopic expression of UNCX impairs the proliferation and differentiation of myeloid cells

scientific article

Expression of spliced oncogenic Ikaros isoforms in Philadelphia-positive acute lymphoblastic leukemia patients treated with tyrosine kinase inhibitors: implications for a new mechanism of resistance

scientific article

Farnesyltransferase inhibition in hematologic malignancies: the clinical experience with tipifarnib.

scientific article published on April 2008

IKAROS deletions dictate a unique gene expression signature in patients with adult B-cell acute lymphoblastic leukemia

scientific article

Identification and molecular characterization of recurrent genomic deletions on 7p12 in the IKZF1 gene in a large cohort of BCR-ABL1-positive acute lymphoblastic leukemia patients: on behalf of Gruppo Italiano Malattie Ematologiche dell'Adulto Acute

scientific article

Identification of different Ikaros cDNA transcripts in Philadelphia-positive adult acute lymphoblastic leukemia by a high-throughput capillary electrophoresis sizing method

article published in 2008

Imatinib mesylate can induce complete molecular remission in FIP1L1-PDGFR-a positive idiopathic hypereosinophilic syndrome.

scientific article published in February 2004

Imatinib mesylate in the treatment of c-kit-positive acute myeloid leukemia: is this the real target?

scientific article published in January 2005

In vitro and in vivo single-agent efficacy of checkpoint kinase inhibition in acute lymphoblastic leukemia

scientific article

Indoleamine 2,3-dioxygenase-expressing leukemic dendritic cells impair a leukemia-specific immune response by inducing potent T regulatory cells

scientific article published on 26 August 2010

JAK2 V617F mutation in essential thrombocythemia: correlation with clinical characteristics, response to therapy and long-term outcome in a cohort of 275 patients

scientific article published in February 2009

Long-term efficacy and safety of nilotinib therapy after imatinib failure in eosinophilic myeloproliferative neoplasm and ETV6-ABL rearrangement.

scientific article

Long-term follow-up of 386 consecutive patients with essential thrombocythemia: safety of cytoreductive therapy

scientific article published in April 2009

Long-term follow-up of essential thrombocythemia in young adults: treatment strategies, major thrombotic complications and pregnancy outcomes. A study of 76 patients

scientific article published on 15 January 2010

Low-dose imatinib mesylate leads to rapid induction of major molecular responses and achievement of complete molecular remission in FIP1L1-PDGFRA-positive chronic eosinophilic leukemia

scientific article published on 13 February 2007

May the correlation between Kit-D816 mutation and AML1-ETO level change the use of prognostic factors in t(8;21) AML?

scientific article

Molecular and chromosomal alterations: new therapies for relapsed acute myeloid leukemia

scientific article published on February 2008

Multicentre phase III trial on fludarabine, cytarabine (Ara-C), and idarubicin versus idarubicin, Ara-C and etoposide for induction treatment of younger, newly diagnosed acute myeloid leukaemia patients

scientific article

NPM1 mutations may reveal acute myeloid leukemia in cases otherwise morphologically diagnosed as myelodysplastic syndromes or myelodysplastic/myeloproliferative neoplasms

scientific article published on 12 May 2015

No preferential sensitivity of t(8;21) acute myeloid leukemias to cytosine arabinoside in vitro: is intensity of therapy or high dose Ara-C crucial for response?

scientific article published in July 2004

Poor outcome of adult acute lymphoblastic leukemia patients carrying the (1;19)(q23;p13) translocation

Rapid detection of Flt3 mutations in acute myeloid leukemia patients by denaturing HPLC.

scientific article published in October 2003

Revealing very small FLT3 ITD mutated clones by ultra-deep sequencing analysis has important clinical implications in AML patients

scientific article published on 5 September 2015

Soft tissue and skeletal involvement in FIP1L1-PDGFR-alpha positive chronic eosinophilic leukemia: imatinib mesylate may induce complete molecular and imaging remission

scientific article published in August 2004

Targeting the p53-MDM2 interaction by the small-molecule MDM2 antagonist Nutlin-3a: a new challenged target therapy in adult Philadelphia positive acute lymphoblastic leukemia patients

scientific article published on 12 February 2016

The relevance of a low JAK2V617F allele burden in clinical practice: a monocentric study

scientific article published on 31 March 2017

Use of a high sensitive nanofluidic array for the detection of rare copies of BCR-ABL1 transcript in patients with Philadelphia-positive acute lymphoblastic leukemia in complete response

scientific article published on 18 February 2014

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