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Authors whose works are in public domain in at least one jurisdiction

List of works by Dirk Hose

A high-risk signature for patients with multiple myeloma established from the molecular classification of human myeloma cell lines

scientific article

A magnetic resonance imaging-based prognostic scoring system to predict outcome in transplant-eligible patients with multiple myeloma

scientific article published on 20 March 2015

A new method for class prediction based on signed-rank algorithms applied to Affymetrix microarray experiments

scientific article

A tissue-based approach to selection of reference genes for quantitative real-time PCR in a sheep osteoporosis model

scientific article published on 19 December 2017

Antigen-mediated regulation in monoclonal gammopathies and myeloma

scientific article published on 19 April 2018

Association between magnetic resonance imaging patterns and baseline disease features in multiple myeloma: analyzing surrogates of tumour mass and biology

scientific article published on 15 January 2016

Autologous retransplantation for patients with recurrent multiple myeloma: a single-center experience with 200 patients

scientific article published on 10 April 2013

Baseline characteristics, chromosomal alterations, and treatment affecting prognosis of deletion 17p in newly diagnosed myeloma

scientific article published on 10 August 2016

Bone marrow stromal cell interaction reduces syndecan-1 expression and induces kinomic changes in myeloma cells

scientific article published on 20 March 2010

Bortezomib induction and maintenance treatment in patients with newly diagnosed multiple myeloma: results of the randomized phase III HOVON-65/ GMMG-HD4 trial

scientific article published on 16 July 2012

CD200 is a new prognostic factor in multiple myeloma

scientific article published on 31 August 2006

CD24, CD27, CD36 and CD302 gene expression for outcome prediction in patients with multiple myeloma

scientific article published on 30 October 2017

Cellular uptake kinetics of bortezomib in relation to efficacy in myeloma cells and the influence of drug transporters

scientific article

Cereblon-binding proteins expression levels correlate with hyperdiploidy in newly diagnosed multiple myeloma patients

scholarly article by Katharina Kriegsmann et al published 29 January 2019 in Blood Cancer Journal

Changes in magnetic resonance imaging before and after autologous stem cell transplantation correlate with response and survival in multiple myeloma

scientific article

Characterization of a transitional preplasmablast population in the process of human B cell to plasma cell differentiation

scientific article

Chetomin, targeting HIF-1α/p300 complex, exhibits antitumour activity in multiple myeloma

scientific article published on 11 February 2016

Combining information regarding chromosomal aberrations t(4;14) and del(17p13) with the International Staging System classification allows stratification of myeloma patients undergoing autologous stem cell transplantation

scientific article

Common variation at 3q26.2, 6p21.33, 17p11.2 and 22q13.1 influences multiple myeloma risk

scientific journal article

Concomitant gain of 1q21 and MYC translocation define a poor prognostic subgroup of hyperdiploid multiple myeloma

scientific article published on 26 November 2015

Cytogenetic intraclonal heterogeneity of plasma cell dyscrasia in AL amyloidosis as compared with multiple myeloma

scientific article published on 01 October 2018

DNA methylation score is predictive of myeloma cell sensitivity to 5-azacitidine

scientific article

DNA repair pathways in human multiple myeloma: role in oncogenesis and potential targets for treatment

scientific article published on 09 August 2013

DNMTi/HDACi combined epigenetic targeted treatment induces reprogramming of myeloma cells in the direction of normal plasma cells

scientific article published on 2 March 2018

Dendritic Glycopolymer as Drug Delivery System for Proteasome Inhibitor Bortezomib in a Calcium Phosphate Bone Cement: First Steps Toward a Local Therapy of Osteolytic Bone Lesions

scientific article published on 28 May 2015

Development of gene expression-based score to predict sensitivity of multiple myeloma cells to DNA methylation inhibitors

scientific article

Drug Release as a function of bioactivity, incubation regime, liquid, and initial load: Release of bortezomib from calcium phosphate-containing silica/collagen xerogels

scientific article published on 29 May 2017

Drug metabolism and clearance system in tumor cells of patients with multiple myeloma

scientific article published on March 2015

Expression of EGF-family receptors and amphiregulin in multiple myeloma. Amphiregulin is a growth factor for myeloma cells

scientific article

Expression of genes encoding for proteins involved in heparan sulphate and chondroitin sulphate chain synthesis and modification in normal and malignant plasma cells

scientific article published on 02 March 2009

Forced KLF4 expression increases the generation of mature plasma cells and uncovers a network linked with plasma cell stage

scientific article published on 26 May 2016

From Bench to Bedside: A View on Bioinformatics Pipelines

scientific article published in January 2017

Gain of chromosome 1q21 is an independent adverse prognostic factor in light chain amyloidosis patients treated with melphalan/dexamethasone

article by Tilmann Bochtler et al published 23 January 2014 in Amyloid

Gene expression of anti- and pro-apoptotic proteins in malignant and normal plasma cells

scientific article

Gene expression profiling and real-time PCR analyses identify novel potential cancer-testis antigens in multiple myeloma

scientific article

Gene expression profiling for molecular classification of multiple myeloma in newly diagnosed patients

scientific article published on 23 June 2010

Gene expression profiling in multiple myeloma--reporting of entities, risk, and targets in clinical routine

scientific article published on 10 October 2011

Genes with a spike expression are clustered in chromosome (sub)bands and spike (sub)bands have a powerful prognostic value in patients with multiple myeloma

scientific article

GenomicScape: an easy-to-use web tool for gene expression data analysis. Application to investigate the molecular events in the differentiation of B cells into plasma cells

scientific article

Growth factors in multiple myeloma: a comprehensive analysis of their expression in tumor cells and bone marrow environment using Affymetrix microarrays

scientific article

Heparanase influences expression and shedding of syndecan-1, and its expression by the bone marrow environment is a bad prognostic factor in multiple myeloma

scientific article

High cereblon expression is associated with better survival in patients with newly diagnosed multiple myeloma treated with thalidomide maintenance.

scientific article published on 11 December 2012

Human reaming debris: a source of multipotent stem cells

scientific article published on 24 November 2004

Hyperdiploidy is less frequent in AL amyloidosis compared with monoclonal gammopathy of undetermined significance and inversely associated with translocation t(11;14).

scientific article published on 10 February 2011

Identification of HLA-A2 restricted T-cell epitopes within the conserved region of the immunoglobulin G heavy-chain in patients with multiple myeloma

scientific article published on 19 March 2008

Identification of a new HLA-A2-restricted T-cell epitope within HM1.24 as immunotherapy target for multiple myeloma

scientific article published in April 2006

Identification of pluripotent and adult stem cell genes unrelated to cell cycle and associated with poor prognosis in multiple myeloma

scientific article

Immunochemical, ultrastructural and electrophysiological investigations of bone-derived stem cells in the course of neuronal differentiation

scientific article published on 18 January 2006

Immunomodulatory drugs thalidomide and lenalidomide affect osteoblast differentiation of human bone marrow stromal cells in vitro.

scientific article published on 2 April 2014

Inherited genetic susceptibility to monoclonal gammopathy of unknown significance

scientific article published on 21 January 2014

Inhibiting the anaphase promoting complex/cyclosome induces a metaphase arrest and cell death in multiple myeloma cells

scientific article published on 26 December 2015

Inhibition of DEPDC1A, a bad prognostic marker in multiple myeloma, delays growth and induces mature plasma cell markers in malignant plasma cells

scientific article published on 2013

Inhibition of aurora kinases for tailored risk-adapted treatment of multiple myeloma

scientific article published on 26 January 2009

Insulin like growth factor binding protein 7 (IGFBP7) expression is linked to poor prognosis but may protect from bone disease in multiple myeloma

scientific article

Krüppel-like factor 4 blocks tumor cell proliferation and promotes drug resistance in multiple myeloma

scientific article published on 12 April 2013

Lenalidomide enhances antigen-specific activity and decreases CD45RA expression of T cells from patients with multiple myeloma

scientific article published on 15 June 2011

Lenalidomide enhances myeloma-specific T-cell responses in vivo and in vitro

scientific article published on 18 February 2016

MYEOV is a prognostic factor in multiple myeloma

scientific article published on 18 September 2010

Melan-A/MART1 analog peptide triggers anti-myeloma T-cells through crossreactivity with HM1.24.

scientific article

Microarray-based understanding of normal and malignant plasma cells

scientific article

Modeling risk stratification in human cancer

scientific article

Molecular pathogenesis of multiple myeloma: chromosomal aberrations, changes in gene expression, cytokine networks, and the bone marrow microenvironment

scientific article published on January 2011

Novel recurrent chromosomal aberrations detected in clonal plasma cells of light chain amyloidosis patients show potential adverse prognostic effect: first results from a genome-wide copy number array analysis

scientific article published on 24 March 2017

Osteoclast-gene expression profiling reveals osteoclast-derived CCR2 chemokines promoting myeloma cell migration

scientific article

Prognostic impact of cytogenetic aberrations in AL amyloidosis patients after high-dose melphalan: a long-term follow-up study

scientific article published on 2 June 2016

Prognostic significance of increased bone marrow microcirculation in newly diagnosed multiple myeloma: results of a prospective DCE-MRI study

scientific article published on 29 July 2015

Progression in smoldering myeloma is independently determined by the chromosomal abnormalities del(17p), t(4;14), gain 1q, hyperdiploidy, and tumor load

scientific article published on 21 October 2013

Proliferation is a central independent prognostic factor and target for personalized and risk-adapted treatment in multiple myeloma

scientific article

Quantification of plasma cell dynamics using mathematical modelling

scientific article published on 24 January 2018

Rationale and design of the German-speaking myeloma multicenter group (GMMG) trial HD6: a randomized phase III trial on the effect of elotuzumab in VRD induction/consolidation and lenalidomide maintenance in patients with newly diagnosed myeloma

article

Report of the European Myeloma Network on multiparametric flow cytometry in multiple myeloma and related disorders

scientific article published on 11 February 2008

STEAP1 is overexpressed in cancers: a promising therapeutic target

scientific article

Sorafenib in patients with refractory or recurrent multiple myeloma

scientific article published on 15 March 2013

Stability of the proteasome inhibitor bortezomib in cell based assays determined by ultra-high performance liquid chromatography coupled to tandem mass spectrometry

T cell-based targeted immunotherapies for patients with multiple myeloma

scientific article published on 19 September 2014

Targeting NF-kappaB pathway with an IKK2 inhibitor induces inhibition of multiple myeloma cell growth

scientific article published on 3 June 2007

Thalidomide maintenance therapy maturates the T cell compartment and compromises antigen-specific antitumor immunity in patients with multiple myeloma

scientific article published on 8 November 2012

The 7p15.3 (rs4487645) association for multiple myeloma shows strong allele-specific regulation of the MYC-interacting gene CDCA7L in malignant plasma cells

scientific article published on 5 December 2014

The CCND1 c.870G>A polymorphism is a risk factor for t(11;14)(q13;q32) multiple myeloma

scientific article

The glycome of normal and malignant plasma cells

scientific article

The role of IGF-1 as a major growth factor for myeloma cell lines and the prognostic relevance of the expression of its receptor

scientific article published on 18 February 2009

Thymosin beta4 in multiple myeloma: friend or foe.

scientific article published on April 2010

Thymosin β4 has tumor suppressive effects and its decreased expression results in poor prognosis and decreased survival in multiple myeloma

scientific article

Timing of the high-dose therapy in the area of new drugs.

scientific article

Translocation t(11;14) is associated with adverse outcome in patients with newly diagnosed AL amyloidosis when treated with bortezomib-based regimens

scientific article published on 16 March 2015

Tumor cells in multiple myeloma patients inhibit myeloma-reactive T cells through carcinoembryonic antigen-related cell adhesion molecule-6.

scientific article published on 19 April 2013

miRNAs in multiple myeloma--a survival relevant complex regulator of gene expression

scientific article published on 12 October 2015

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