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List of works by Shmuel Yaccoby

A Cyclin-Dependent Kinase Inhibitor, Dinaciclib, Impairs Homologous Recombination and Sensitizes Multiple Myeloma Cells to PARP Inhibition

scientific article published on 30 December 2015

A peptide nucleic acid targeting nuclear RAD51 sensitizes multiple myeloma cells to melphalan treatment

scientific article published on 21 May 2015

A prospective evaluation of the biochemical, metabolic, hormonal and structural bone changes associated with bortezomib response in multiple myeloma patients ⬇️

scientific article published on October 15, 2010

Advances in the understanding of myeloma bone disease and tumour growth

scientific article

Adverse Metaphase Cytogenetics Can Be Overcome by Adding Bortezomib and Thalidomide to Fractionated Melphalan Transplants.

scientific article published on 3 November 2016

Antibody-based inhibition of DKK1 suppresses tumor-induced bone resorption and multiple myeloma growth in vivo

scientific article published on 26 October 2006

Antimyeloma efficacy of thalidomide in the SCID-hu model

scientific article published on 8 August 2002

CYR61/CCN1 overexpression in the myeloma microenvironment is associated with superior survival and reduced bone disease

scientific article

Cancer and the microenvironment: myeloma-osteoclast interactions as a model

scientific article published in March 2004

Characterization of the molecular mechanism of the bone-anabolic activity of carfilzomib in multiple myeloma

scientific article

Combinatorial efficacy of anti-CS1 monoclonal antibody elotuzumab (HuLuc63) and bortezomib against multiple myeloma

scientific article published on September 2009

Consequences of Daily Administered Parathyroid Hormone on Myeloma Growth, Bone Disease, and Molecular Profiling of Whole Myelomatous Bone ⬇️

scientific article published on December 20, 2010

Consequences of interactions between the bone marrow stroma and myeloma

scientific article published on January 1, 2003

Ellipticine derivative NSC 338258 represents a potential new antineoplastic agent for the treatment of multiple myeloma

scientific article

Establishment and exploitation of hyperdiploid and non-hyperdiploid human myeloma cell lines

scientific article published on September 2007

Ex vivo-expanded natural killer cells demonstrate robust proliferation in vivo in high-risk relapsed multiple myeloma patients

scientific article

Fenretinide inhibits myeloma cell growth, osteoclastogenesis and osteoclast viability

scientific article published on 15 May 2009

Fibroblast activation protein (FAP) is upregulated in myelomatous bone and supports myeloma cell survival

scientific article published in April 2006

Four genes predict high risk of progression from smoldering to symptomatic multiple myeloma (SWOG S0120).

scientific article published on 28 May 2015

Highly activated and expanded natural killer cells for multiple myeloma immunotherapy ⬇️

scientific article published on March 14, 2012

Human Placenta-Derived Adherent Cells Prevent Bone loss, Stimulate Bone formation, and Suppress Growth of Multiple Myeloma in Bone ⬇️

scientific article published on February 1, 2011

Identification of early growth response protein 1 (EGR-1) as a novel target for JUN-induced apoptosis in multiple myeloma

scientific article

Inhibitor of DASH proteases affects expression of adhesion molecules in osteoclasts and reduces myeloma growth and bone disease

scientific article published on 08 April 2009

Inhibitory effects of osteoblasts and increased bone formation on myeloma in novel culture systems and a myelomatous mouse model

scientific article

Low expression of hexokinase-2 is associated with false-negative FDG-positron emission tomography in multiple myeloma

scientific article published on 21 April 2017

Monoclonal antibody therapy in multiple myeloma: where do we stand and where are we going?

scientific article published on 17 February 2016

Myeloma interacts with the bone marrow microenvironment to induce osteoclastogenesis and is dependent on osteoclast activity

scientific article published in February 2002

NAMPT/PBEF1 enzymatic activity is indispensable for myeloma cell growth and osteoclast activity

scientific article

Osteoblastogenesis and tumor growth in myeloma

scientific article

Primary myeloma interaction and growth in coculture with healthy donor hematopoietic bone marrow

scientific article published on 6 November 2015

Repression of multiple myeloma growth and preservation of bone with combined radiotherapy and anti-angiogenic agent

scientific article

Response to bortezomib and activation of osteoblasts in multiple myeloma

scientific article published on September 2006

Response to bortezomib is associated to osteoblastic activation in patients with multiple myeloma

scientific article published in October 2005

Risk factors for MDS and acute leukemia following total therapy 2 and 3 for multiple myeloma

scientific article published on 19 April 2013

Role of Bruton's tyrosine kinase in myeloma cell migration and induction of bone disease

scientific article published on 28 March 2013

Role of decorin in the antimyeloma effects of osteoblasts

scientific article published on 24 April 2008

Seven-year median time to progression with thalidomide for smoldering myeloma: partial response identifies subset requiring earlier salvage therapy for symptomatic disease

scientific article

Soluble syndecan-1 promotes growth of myeloma tumors in vivo

scientific article (publication date: 15 July 2002)

Standard and novel imaging methods for multiple myeloma: correlates with prognostic laboratory variables including gene expression profiling data ⬇️

scientific article published on June 24, 2012

Targeting beta2-microglobulin for induction of tumor apoptosis in human hematological malignancies

scientific article published on October 2006

The ephrinB2/EphB4 axis is dysregulated in osteoprogenitors from myeloma patients and its activation affects myeloma bone disease and tumor growth

scientific article published on 13 July 2009

The molecular classification of multiple myeloma

scientific article

The oxidative stress response regulates DKK1 expression through the JNK signaling cascade in multiple myeloma plasma cells

scientific article published on 25 January 2007

The phenotypic plasticity of myeloma plasma cells as expressed by dedifferentiation into an immature, resilient, and apoptosis-resistant phenotype

scientific article

The presence of large focal lesions is a strong independent prognostic factor in multiple myeloma

scientific article published on 5 July 2018

The prognostic value of the depth of response in multiple myeloma depends on the time of assessment, risk status and molecular subtype

scientific article published on 18 May 2017

The proteasome inhibitor, bortezomib suppresses primary myeloma and stimulates bone formation in myelomatous and nonmyelomatous bones in vivo

scientific article published on January 2009

The syndecan-1 heparan sulfate proteoglycan is a viable target for myeloma therapy

scientific article

Therapeutic effects of intrabone and systemic mesenchymal stem cell cytotherapy on myeloma bone disease and tumor growth

scientific article

Two States of Myeloma Stem Cells

scientific article published on 3 October 2017

Wnt3a signaling within bone inhibits multiple myeloma bone disease and tumor growth

scientific article published on 14 March 2008

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